MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Euthyroid Sick Syndromes

(UMLS:C0015190)

Definition:: Conditions of abnormal THYROID HORMONES release in patients with apparently normal THYROID GLAND during severe systemic illness, physical TRAUMA, and psychiatric disturbances. It can be caused by the loss of endogenous hypothalamic input or by exogenous drug effects. The most common abnormality results in low T3 THYROID HORMONE with progressive decrease in THYROXINE; (T4) and TSH. Elevated T4 with normal T3 may be seen in diseases in which THYROXINE-BINDING GLOBULIN synthesis and release are increased.
UMLS ID:: C0015190
MeSH ID:: D005067

Classification:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.874.255

Synonym(s)

Euthyroid Sick Syndromes

EUTHYROID SICK SYNDROME

EUTHYROID SICK SYNDROME LOW T3 LOW T4 SYNDROME

Euthyroid Sick Syndrome

Euthyroid sick syndrome

SICK EUTHYROID SYNDROME

Sick Euthyroid Syndrome

Sick euthyroid syndrome

Sick-euthyroid syndrome

10.

euthyroid sick syndrome

11.

sick euthyroid syndrome

12.

sick-euthyroid; syndrome

13.

syndrome; sick-euthyroid

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Carbimazole	8542214	CTD
2	Prednisolone	8542214	CTD
3	Propylthiouracil	8542214	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Goiter	42.9%
2	Hyperthyroidism	42.9%
3	Hyperthyroxinemia	42.9%
4	Hypothyroidism	42.9%
5	Thyroiditis	42.9%
6	Secondary hypothyroidism	42.9%
7	Primary Hyperthyroidism	42.9%
8	Primary Hypothyroidism	42.9%
9	Thyrotoxicosis	31%
10	Thyroid Hormone Resistance Syndrome	31%
11	Hashimoto Disease	25.4%
12	Graves Disease	24.7%
13	Adrenal Gland Diseases	23.1%
14	Gonadal Disorders	23.1%
15	Parathyroid Diseases	23.1%
16	Thyroid Neoplasm	22.2%
17	Thyroid carcinoma	22.2%
18	Autoimmune thyroiditis	20.9%
19	Myxedema	20.5%
20	Thyroid Nodule	16%
21	Bone Diseases, Endocrine	15%
22	Endocrine Gland Neoplasms	15%
23	Congenital Hypothyroidism	14.7%
24	Diabetes Mellitus	14.6%
25	Pituitary Diseases	14.5%
26	Adrenal Cortex Diseases	14.3%
27	Hyperparathyroidism	14.3%
28	Hypogonadism	14.3%
29	Hypoparathyroidism	14.3%
30	Delayed Puberty	14.3%
31	Precocious Puberty	14.3%
32	Hypogonadotropic hypogonadism	14.3%
33	Testotoxicosis	14.3%
34	Adrenal Gland Neoplasms	14%
35	Parathyroid Neoplasms	11.1%
36	Dwarfism	10.9%
37	Cushing Syndrome	10.3%
38	Hyperaldosteronism	10.3%
39	Hyperparathyroidism, Secondary	10.3%
40	Hypoaldosteronism	10.3%
41	Hyperparathyroidism, Primary	10.3%
42	Testicular Diseases	9.5%
43	Ovarian Diseases	9.2%
44	Empty Sella Syndrome	9.1%
45	Hyperpituitarism	9.1%
46	Hypopituitarism	9.1%
47	Hypophysitis	9.1%
48	Hyperglycemic Hyperosmolar Nonketotic Coma	8.5%
49	Adrenocortical carcinoma	8.2%
50	ovarian neoplasm	7.8%
51	Addison Disease	7%
52	Diabetic Angiopathies	7%
53	Primary Adrenal Insufficiency	7%
54	Gestational Diabetes	7%
55	Latent Autoimmune Diabetes in Adults	7%
56	Diabetes Insipidus	6.8%
57	Diabetes Mellitus, Experimental	6.8%
58	Diabetic Neuropathies	6.8%
59	Orchitis	6.8%
60	Diabetic Amyotrophy	6.8%
61	Diabetic Autonomic Neuropathy	6.8%
62	Diabetic Cardiomyopathies	6.8%
63	Testicular Neoplasms	6.8%
64	Ovarian Hyperstimulation Syndrome	6.7%
65	Hyperprolactinemia	6.7%
66	Prolactinoma	6.6%
67	Growth Hormone-Secreting Pituitary Adenoma	6.6%
68	Diabetic Foot	6.6%
69	Nelson Syndrome	6.5%
70	Pituitary Adenoma	5.9%
71	Pituitary Neoplasms	5.9%
72	Hermaphroditism	5.6%
73	Disorders of Sex Development	5.6%
74	Pituitary Apoplexy	5.3%
75	Kallmann Syndrome	5.2%
76	granulosa cell tumor	5.1%
77	Carcinoma, Ovarian Epithelial	5.1%
78	Corpus Luteum Cyst	5.1%
79	Ovarian Cysts	5.1%
80	Gigantism	5.1%
81	Diabetic Nephropathy	5%
82	Acromegaly	5%
83	Anovulation	5%
84	Diabetic Ketoacidosis	5%
85	Oophoritis	5%
86	Multiple Endocrine Neoplasia	4.7%
87	Pancreatic Neoplasm	4.7%
88	Klinefelter Syndrome	4.5%
89	Diabetic Retinopathy	4.3%
90	Polycystic Ovary Syndrome	4.1%
91	Cryptorchidism	4.1%
92	Gonadal Dysgenesis	4%
93	Adrenogenital Syndrome	4%
94	Ovotesticular Disorders of Sex Development	4%
95	Leydig Cell Tumor	3.8%
96	Hyperandrogenism	3.6%
97	Multiple Endocrine Neoplasia Type 1	3.3%
98	Carcinoma, Pancreatic Ductal	2.5%
99	insulinoma	2.3%
100	Gastrinoma	2.3%
101	Glucagonoma	2.3%
102	Turner Syndrome	2.3%
103	Carcinoma, Endometrioid	2.3%
104	Renal Osteodystrophy	2%
105	Renal rickets	2%
106	Vipoma	2%
107	Waterhouse-Friderichsen Syndrome	2%
108	Denys-Drash Syndrome	1.2%
109	Adrenoleukodystrophy	1.1%

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