MetaADEDB 2.0 @ LMMD
Clofibrate
(KNHUKKLJHYUCFP-UHFFFAOYSA-N)
Structure
SMILES
CCOC(=O)C(Oc1ccc(cc1)Cl)(C)C
Type(s)
Approved; Investigational
ATC code(s)
C10AB01
Molecular Formula:
C12H15ClO3
Molecular Weight:
242.699
Log P:
3.0605
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
35.53
CAS Number(s):
637-07-0
Synonym(s)
1.
Clofibrate
2.
Athromidin
3.
Atromid
4.
Atromid S
5.
Clofibric Acid, Ethyl Ester
6.
Ethyl Chlorophenoxyisobutyrate
7.
Miscleron
8.
Miskleron
9.
Chlorophenoxyisobutyrate, Ethyl
External Link(s)
MeSHD002994
PubChem Compound2796
BindingDB50085047
ChEBI3750
CHEMBLCHEMBL565
DrugBankDB00636
DrugCentral694
IUPHAR/BPS Guide to PHARMACOLOGY2667
KEGGcpd:C06916
dr:D00279
Therapeutic Target DatabaseD0J5DC
ZINC56648
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute kidney injury55557
7437867
12503032		CTD
2Angina Pectoris795299CTD
3Atherosclerosis20573577CTD
4Back Pain55557
7437867		CTD
5Blood Coagulation Disorders19483382CTD
6Cardiomyopathies846520CTD
7Chemical and Drug Induced Liver Injury

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3714094
8742320
11006363
16924418
17188792
17585979
28495587
 		CTD
8Chest Pain3142389CTD
9Cholecystitis3547004CTD
10Cholelithiasis3547004
7157849		CTD
11Dermatitis, Allergic Contact11851881CTD
12Dermatitis, Irritant11851881CTD
13Dermatofibrosarcoma508572CTD
14Diabetes Insipidus846520CTD
15Diabetic Ketoacidosis416322CTD
16Disseminated Intravascular Coagulation6728507CTD
17Dyslipidemias9515185
16707586		CTD
18Dyspnea3515563CTD
19Edema661938CTD
20Erectile dysfunctionCanada Vigilance: 250074CTD
Canada Vigilance
21Exanthema7437867CTD
22FatigueCanada Vigilance: 1Canada Vigilance
23Fatty Liver, Alcoholic15016835CTD
24Fatty Liver15200495
16872304
19224547		CTD
25Gastrointestinal Neoplasms3547004CTD
26Granuloma661938CTD
27HeadacheCanada Vigilance: 1Canada Vigilance
28Heart Diseases6728507CTD
29Hemorrhage7206007CTD
30Hepatomegaly

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661938
2260096
3590187
3625448
6424681
6606240
8700121
9007043
11969379
12851107
15033592
18670166
19952500
20637823
22008526
22008536
22467018
28108177
28495587
 		CTD
31Hypercholesterolemia1175893
7080553
7157849		CTD
32Hyperglycemia11918743CTD
33Hyperlipoproteinemia Type IV417937CTD
34Hyperlipoproteinemias7080553
7157849		CTD
35Hyperoxaluria9030817CTD
36Hyperplasia9207284
10951269		CTD
37Hypertriglyceridemia

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226883
1143089
7080553
7157849
8593127
 		CTD
38Hypertrophy633072
28495587		CTD
39Inflammation15016835CTD
40Kidney Diseases21338618CTD
41Liver Neoplasms, Experimental

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728341
6850573
7139857
8055661
8597128
8968061
10600397
16800819
17636249
21035526
21214675
 		CTD
42Liver diseases

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8994295
9207284
10550479
10569642
 		CTD
43Liver neoplasms

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22084566
25058030
28108177
28899750
 		CTD
44Mitochondrial Diseases17499714CTD
45Mitochondrial Myopathies4072624
17562484		CTD
46Muscle Weakness

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54800
62135
63766
799549
3515563
6511338
 		CTD
47Muscular Atrophy6511338CTD
48MyalgiaCanada Vigilance: 1Canada Vigilance
49Myocardial Infarction666886
1874539
12087064		CTD
50Myoglobinuria846520CTD
51MyopathyCanada Vigilance: 2Canada Vigilance
52Myositis3547004CTD
53Nausea7437867CTD
54Necrosis

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661938
8742320
15016835
16465232
 		CTD
55Neoplasm Metastasis21080969CTD
56Nephritis, Interstitial7437867CTD
57Nephrotic SyndromeCanada Vigilance: 1Canada Vigilance
58Neurologic Manifestations1307471CTD
59Neuromuscular Diseases62135CTD
60Neuromuscular Manifestations63766CTD
61Niemann-Pick Disease, Type C9802331CTD
62Pain

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63766
204061
2089182
4115569
4126124
 		CTD
63Polyuria4115569CTD
64Precancerous Conditions

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2869179
8968061
20180811
21214675
 		CTD
65PruritusCanada Vigilance: 1Canada Vigilance
66Pulmonary Edema7206007CTD
67Rash follicularCanada Vigilance: 1Canada Vigilance
68Substance Withdrawal Syndrome532624CTD
69Uremia55557CTD
70Urinary RetentionCanada Vigilance: 1Canada Vigilance
71VomitingCanada Vigilance: 155557CTD
Canada Vigilance
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