MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Anovulation

(UMLS:C0003128)

Definition:: Suspension or cessation of OVULATION in animals or humans with follicle-containing ovaries (OVARIAN FOLLICLE). Depending on the etiology, OVULATION may be induced with appropriate therapy.
UMLS ID:: C0003128
MeSH ID:: D000858

Classification 1:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.500.056.630.050

Classification 2:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.391.630.050

Classification 3:

Name:

Reproductive and Urinary Physiological Phenomena
MeSH Tree Number(s):: G08.686.784.690.080

Synonym(s)

Anovulation

OVULATION FAILURE

Ovulation absent

absent ovulation

anovulation

failure; ovulation

ovulation absent

ovulation failure

ovulation; failure

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Clomiphene	7570363 18161408	CTD
2	Diethylhexyl Phthalate	19874833	CTD
3	Dihydrotestosterone	23690868	CTD
4	Letrozole	28619389	CTD
5	Linagliptin	28619389	CTD
6	Medroxyprogesterone		SIDER
7	Norethindrone		SIDER
8	Norinyl	26820455	CTD
9	indole-3-carbinol	28619389	CTD
10	mono-(2-ethylhexyl)phthalate	19874833	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Oophoritis	39.9%
2	Ovarian Hyperstimulation Syndrome	38.3%
3	Corpus Luteum Cyst	32.4%
4	Ovarian Cysts	32.4%
5	ovarian neoplasm	28.6%
6	Polycystic Ovary Syndrome	23.9%
7	Premature Menopause	22.3%
8	Salpingitis	19.3%
9	Multiple Pregnancy	19.1%
10	granulosa cell tumor	18.4%
11	Carcinoma, Ovarian Epithelial	18.4%
12	Carcinoma, Endometrioid	17.6%
13	Fertilization	17.1%
14	Pregnancy	17.1%
15	Endometritis	16.5%
16	Superovulation	16.2%
17	Puberty	15.9%
18	Hypogonadism	14.9%
19	Delayed Puberty	14.9%
20	Precocious Puberty	14.9%
21	Hypogonadotropic hypogonadism	14.9%
22	Testotoxicosis	14.9%
23	Adnexitis	14.7%
24	Pelvic Inflammatory Disease	14.7%
25	Endometriosis	14.3%
26	Uterine Diseases	14.3%
27	Vaginal Diseases	14.3%
28	Vulvar Diseases	14.3%
29	Endometrioma	14.3%
30	Hermaphroditism	12.2%
31	Disorders of Sex Development	12.2%
32	Testicular Diseases	12.1%
33	Parametritis	12.1%
34	Infertility	11.6%
35	Unwanted pregnancy	11.3%
36	Breech Presentation	11%
37	Fallopian Tube Neoplasms	10.5%
38	Menarche	9.8%
39	Menopause	9.8%
40	Andropause	9.8%
41	Urologic Diseases	9.3%
42	Vulvovaginitis	9%
43	Kallmann Syndrome	8.7%
44	Sexually Transmitted Diseases	8.6%
45	Adrenal Gland Diseases	8.6%
46	Parathyroid Diseases	8.6%
47	Thyroid Diseases	8.6%
48	Endometrial Hyperplasia	8.5%
49	Pyometra	8.5%
50	Vaginitis	8.5%
51	Vulvitis	8.5%
52	Vaginal Discharge	8.5%
53	Vulvodynia	8.5%
54	Uterine Inversion	8.5%
55	Live Birth	8.5%
56	Genital Herpes	8.3%
57	Uterine Neoplasms	8.1%
58	Vaginal Neoplasms	8.1%
59	Vulvar Neoplasms	8.1%
60	Uterine Cancer	8.1%
61	Orchitis	7.9%
62	Urogenital Abnormalities	7.8%
63	Klinefelter Syndrome	7.7%
64	Gonadal Dysgenesis	7.7%
65	Adrenogenital Syndrome	7.7%
66	Ovotesticular Disorders of Sex Development	7.7%
67	Pregnancy Complications	7.3%
68	Uterine Rupture	7.2%
69	Stillbirth	7%
70	Hyperandrogenism	7%
71	Bone Diseases, Endocrine	6.9%
72	Endocrine Gland Neoplasms	6.9%
73	Pruritus Vulvae	6.8%
74	Uterine hemorrhage	6.8%
75	Vaginal Fistula	6.8%
76	Diabetes Mellitus	6.8%
77	Uterine Prolapse	6.8%
78	Vaginal Prolapse	6.8%
79	Pituitary Diseases	6.8%
80	Postmenopause	6.8%
81	Adrenal Gland Neoplasms	6.7%
82	Testicular Neoplasms	6.6%
83	Bisexuality	5.9%
84	Homosexuality	5.9%
85	Gestational Diabetes	5.8%
86	Diabetes Insipidus	5.8%
87	Dyspareunia	5.8%
88	Parathyroid Neoplasms	5.8%
89	Thyroid Neoplasm	5.8%
90	Thyroid carcinoma	5.8%
91	Dwarfism	5.7%
92	Cryptorchidism	5.7%
93	Uterine Cervicitis	5.6%
94	Leukorrhea	5.6%
95	Candidiasis, Vulvovaginal	5.6%
96	Uterine Cervical Incompetence	5.5%
97	Endometrial Neoplasms	5.3%
98	Vesicovaginal Fistula	5.2%
99	Urinary Bladder Diseases	5%
100	Kidney Diseases	5%
101	Ureteral Diseases	5%
102	Urethral Diseases	5%
103	Urination Disorders	5%
104	Urolithiasis	5%
105	Adrenal Cortex Diseases	5%
106	Euthyroid Sick Syndromes	5%
107	Goiter	5%
108	Hyperparathyroidism	5%
109	Hyperthyroidism	5%
110	Hyperthyroxinemia	5%
111	Hypoparathyroidism	5%
112	Hypothyroidism	5%
113	Thyroiditis	5%
114	Secondary hypothyroidism	5%
115	Primary Hyperthyroidism	5%
116	Primary Hypothyroidism	5%
117	Bladder Exstrophy	5%
118	Epispadias	5%
119	Tuberculosis, Renal	4.9%
120	Genital Neoplasms, Female	4.9%
121	Fetal Weight	4.9%
122	Turner Syndrome	4.8%
123	Diabetic Nephropathy	4.6%
124	Bacterial Vaginosis	4.6%
125	Trichomonas Vaginitis	4.5%
126	Uterine Perforation	4.5%
127	Metrorrhagia	4.5%
128	Multicystic Dysplastic Kidney	4.3%
129	Urinary tract infection	4.2%
130	Anuria	4.2%
131	Ureterolithiasis	4.2%
132	Nephrolithiasis	4.2%
133	Urologic Neoplasms	4.2%
134	Horseshoe Kidney	4.2%
135	Diuresis	4.1%
136	Congenital Hypothyroidism	4.1%
137	Empty Sella Syndrome	3.9%
138	Hyperpituitarism	3.9%
139	Hypopituitarism	3.9%
140	Hypophysitis	3.9%
141	Graves Disease	3.8%
142	Menorrhagia	3.8%
143	Polyhydramnios	3.7%
144	Obstetric Labor Complications	3.7%
145	Ectopic Pregnancy	3.7%
146	Pregnancy, Prolonged	3.7%
147	Puerperal Disorders	3.7%
148	Oligohydramnios	3.7%
149	Prenatal Injuries	3.7%
150	Thyroid Nodule	3.7%
151	Urinary Bladder Fistula	3.7%
152	Bladder Neoplasm	3.7%
153	Kidney Neoplasm	3.7%
154	Ureteral Neoplasms	3.7%
155	Urethral Neoplasms	3.7%
156	Adrenocortical carcinoma	3.6%
157	Hypospadias	3.6%
158	Pituitary Adenoma	3.6%
159	Pituitary Neoplasms	3.6%
160	Denys-Drash Syndrome	3.5%
161	Bladder neck obstruction	3.5%
162	Leydig Cell Tumor	3.4%
163	Latent Autoimmune Diabetes in Adults	3.3%
164	Diabetes Mellitus, Experimental	3.3%
165	Glomerular Filtration Rate	3.3%
166	Abruptio Placentae	3.3%
167	Placenta Accreta	3.3%
168	Cushing Syndrome	3.3%
169	Hyperaldosteronism	3.3%
170	Hyperparathyroidism, Secondary	3.3%
171	Hypoaldosteronism	3.3%
172	Thyrotoxicosis	3.3%
173	Hyperparathyroidism, Primary	3.3%
174	Thyroid Hormone Resistance Syndrome	3.3%
175	Prolactinoma	3.2%
176	Growth Hormone-Secreting Pituitary Adenoma	3.2%
177	Fetal Diseases	3.1%
178	Pregnancy Complications, Cardiovascular	3.1%
179	Pregnancy Complications, Neoplastic	3.1%
180	Chorioamnionitis	3.1%
181	Pregnancy Complications, Hematologic	3%
182	Pregnancy Complications, Infectious	3%
183	Fetal Death	3%
184	Perinatal death	3%
185	Morning Sickness	3%
186	Cystitis	2.9%
187	Hydronephrosis	2.9%
188	Hyperoxaluria	2.9%
189	Kidney Cortex Necrosis	2.9%
190	Kidney Papillary Necrosis	2.9%
191	Nephritis	2.9%
192	Nephrosclerosis	2.9%
193	Nephrosis	2.9%
194	Perinephritis	2.9%
195	Kidney Failure	2.9%
196	Uremia	2.9%
197	Ureteral obstruction	2.9%
198	Ureterocele	2.9%
199	Urethral Obstruction	2.9%
200	Urethritis	2.9%
201	Vesico-Ureteral Reflux	2.9%
202	Urinary Retention	2.9%
203	Oxalosis	2.9%
204	Renal Insufficiency	2.9%
205	Kidney Calculi	2.9%
206	Ureteral Calculi	2.9%
207	Endometrial Stromal Sarcoma	2.9%
208	Chlamydia Infections	2.8%
209	Gonorrhea	2.8%
210	Pituitary Apoplexy	2.8%
211	Diabetic Foot	2.8%
212	Nelson Syndrome	2.8%
213	Puerperal Infection	2.7%
214	Postpartum Hemorrhage	2.7%
215	Addison Disease	2.7%
216	Diabetic Angiopathies	2.7%
217	Autoimmune thyroiditis	2.7%
218	Primary Adrenal Insufficiency	2.7%
219	Diabetic Neuropathies	2.6%
220	Myxedema	2.6%
221	Diabetic Amyotrophy	2.6%
222	Diabetic Autonomic Neuropathy	2.6%
223	Diabetic Cardiomyopathies	2.6%
224	Hyperprolactinemia	2.6%
225	Multiple Endocrine Neoplasia	2.5%
226	Pancreatic Neoplasm	2.5%
227	Syphilis	2.5%
228	Hepatorenal Syndrome	2.5%
229	Bacteriuria	2.5%
230	Glycosuria	2.5%
231	Hematuria	2.5%
232	Renal hypertension	2.5%
233	Oliguria	2.5%
234	Polyuria	2.5%
235	Proteinuria	2.5%
236	Pyuria	2.5%
237	Renal Artery Obstruction	2.5%
238	Renal Artery Stenosis	2.5%
239	Urinary Calculi	2.5%
240	Cystocele	2.4%
241	Nephrocalcinosis	2.4%
242	Urinary Incontinence	2.4%
243	Hyperglycemic Hyperosmolar Nonketotic Coma	2.4%
244	Hashimoto Disease	2.4%
245	Renal Osteodystrophy	2.4%
246	Renal rickets	2.4%
247	Pyelocystitis	2.4%
248	Gigantism	2.2%
249	Acromegaly	2.2%
250	Diabetic Ketoacidosis	2.2%
251	Mesoblastic Nephroma	2.2%
252	Renal Cell Carcinoma	2.1%
253	Papillary Renal Cell Carcinoma	2.1%
254	Enuresis	2.1%
255	Lymphogranuloma Venereum	2.1%
256	Pyelonephritis	2.1%
257	Abortion, Habitual	2%
258	Dystocia	2%
259	Eclampsia	2%
260	Fetal Membranes, Premature Rupture	2%
261	Placental Insufficiency	2%
262	Pre-Eclampsia	2%
263	Prenatal Exposure Delayed Effects	2%
264	HELLP Syndrome	2%
265	Placenta, Retained	2%
266	Glomerulonephritis	1.9%
267	Nephritis, Interstitial	1.9%
268	Lipoid nephrosis	1.9%
269	Nephrotic Syndrome	1.9%
270	Pyelitis	1.9%
271	Pyonephrosis	1.9%
272	Urethral Stenosis	1.9%
273	Nephrogenic Diabetes Insipidus	1.9%
274	Congenital Nephrogenic Diabetes Insipidus	1.9%
275	Acute kidney injury	1.9%
276	Urethral stricture	1.9%
277	Glycosuria, Renal	1.9%
278	AIDS-Associated Nephropathy	1.8%
279	Nephroblastoma	1.8%
280	Abortion, Veterinary	1.7%
281	Pregnancy Complications, Parasitic	1.7%
282	Diabetic Retinopathy	1.7%
283	Lactation Disorder	1.6%
284	Mastitis	1.6%
285	Depression, Postpartum	1.6%
286	Azotemia	1.6%
287	Embryo Loss	1.6%
288	Multiple Endocrine Neoplasia Type 1	1.6%
289	Fetal Resorption	1.6%
290	Hyperemesis Gravidarum	1.6%
291	Albuminuria	1.6%
292	Hemoglobinuria	1.6%
293	Hypertension, Renovascular	1.6%
294	Urge Incontinence	1.6%
295	Balkan Nephropathy	1.4%
296	Focal glomerulosclerosis	1.4%
297	Kidney Failure, Chronic	1.4%
298	Polycystic Kidney Diseases	1.4%
299	Diurnal Enuresis	1.4%
300	Fetal Growth Retardation	1.4%
301	Trophoblastic Neoplasms	1.4%
302	Renal Aminoacidurias	1.4%
303	Fanconi Syndrome	1.4%
304	Pseudohypoaldosteronism	1.4%
305	Liddle Syndrome	1.4%
306	Hemolytic-Uremic Syndrome	1.4%
307	Embolism, Amniotic Fluid	1.4%
308	Fetal Hypoxia	1.4%
309	Fetal Alcohol Spectrum Disorders	1.4%
310	Carcinoma, Pancreatic Ductal	1.3%
311	Glomerulonephritis, Membranoproliferative	1.3%
312	Premature Birth	1.2%
313	Renal tubular acidosis	1.2%
314	Zellweger Syndrome	1.1%
315	Waterhouse-Friderichsen Syndrome	1.1%
316	insulinoma	1.1%
317	Gastrinoma	1.1%
318	Glucagonoma	1.1%
319	Meconium Aspiration Syndrome	1.1%
320	Anti-Glomerular Basement Membrane Disease	1.1%
321	Lupus Nephritis	1%
322	Polycystic Kidney, Autosomal Dominant	1%
323	Cystinuria	1%
324	Atypical Hemolytic Uremic Syndrome	1%
325	Galactorrhea	1%
326	Hyperphosphaturia	1%
327	Vipoma	1%
328	Choriocarcinoma	0.7%
329	Adrenoleukodystrophy	0.7%
330	Hydatidiform Mole	0.5%
331	Hydrops Fetalis	0.5%
332	Familial Hypophosphatemic Rickets	0.5%

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