MetaADEDB 2.0 @ LMMD
Oseltamivir
(VSZGPKBBMSAYNT-RRFJBIMHSA-N)
Structure
SMILES
CCOC(=O)C1=C[C@H]([C@@H]([C@H](C1)N)NC(=O)C)OC(CC)CC
Type(s)
Approved
ATC code(s)
J05AH02
Molecular Formula:
C16H28N2O4
Molecular Weight:
312.405
Log P:
2.3766
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
90.65
CAS Number(s):
196618-13-0
Synonym(s)
1.
Oseltamivir
2.
GS 4071
3.
GS 4104
4.
GS-4071
5.
GS-4104
6.
GS4071
7.
GS4104
8.
Tamiflu
External Link(s)
MeSHD053139
PubChem Compound65028
BindingDB5025
ChEBI7798
CHEMBLCHEMBL1229
DrugBankDB00198
DrugCentral2001
KEGGcpd:C08092
dr:D00900
dr:D08306
Therapeutic Target DatabaseD0O5NK
ZINC3929508
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1No adverse eventFAERS: 111US FAERS
2Drug exposure during pregnancyFAERS: 60OFFSIDES
US FAERS
3Pathogen resistanceFAERS: 57OFFSIDES
US FAERS
4PregnancyFAERS: 54US FAERS
5Drug ineffectiveFAERS: 49US FAERS
6PneumoniaFAERS: 33SIDER
US FAERS
7Respiratory FailureFAERS: 28OFFSIDES
US FAERS
8VomitingFAERS: 27SIDER
US FAERS
9Drug resistanceFAERS: 15OFFSIDES
US FAERS
10ThrombocytopeniaFAERS: 13SIDER
US FAERS
11InfluenzaFAERS: 10SIDER
US FAERS
12LeukopeniaFAERS: 9US FAERS
13Maternal exposure during pregnancyFAERS: 9US FAERS
14NauseaFAERS: 9SIDER
US FAERS
15DeliriumFAERS: 8SIDER
US FAERS
16HeadacheFAERS: 8SIDER
US FAERS
17AnxietyFAERS: 7OFFSIDES
SIDER
US FAERS
18DehydrationFAERS: 6OFFSIDES
US FAERS
19Maternal exposure timing unspecifiedFAERS: 6US FAERS
20StillbirthFAERS: 6US FAERS
21Alanine aminotransferase abnormalFAERS: 5OFFSIDES
US FAERS
22Aspartate aminotransferase abnormalFAERS: 5OFFSIDES
US FAERS
23Product taste abnormalFAERS: 5US FAERS
24Respiratory distressFAERS: 5US FAERS
25ScreamingFAERS: 5OFFSIDES
US FAERS
26SepsisFAERS: 5US FAERS
27ShockFAERS: 5US FAERS
28BronchitisFAERS: 4SIDER
US FAERS
29EczemaFAERS: 4SIDER
US FAERS
30ErythemaFAERS: 4US FAERS
31Otitis MediaFAERS: 4SIDER
US FAERS
32PainFAERS: 4SIDER
US FAERS
33PeriproctitisFAERS: 4OFFSIDES
US FAERS
34PharyngitisFAERS: 4US FAERS
35PruritusFAERS: 4US FAERS
36Stevens-Johnson SyndromeFAERS: 425811541CTD
OFFSIDES
SIDER
US FAERS
37Acute Coronary SyndromeFAERS: 3US FAERS
38AgitationFAERS: 3SIDER
US FAERS
39AstheniaFAERS: 3SIDER
US FAERS
40AsthmaFAERS: 3SIDER
US FAERS
41Cardiac ArrestFAERS: 3US FAERS
42CryingFAERS: 3OFFSIDES
US FAERS
43Diabetic KetoacidosisFAERS: 3US FAERS
44DisorientationFAERS: 3US FAERS
45DizzinessFAERS: 3SIDER
US FAERS
46Emotional distressFAERS: 3US FAERS
47EncephalitisFAERS: 3OFFSIDES
SIDER
US FAERS
48FatigueFAERS: 3SIDER
US FAERS
49Live BirthFAERS: 3OFFSIDES
US FAERS
50LymphopeniaFAERS: 3US FAERS
51Oropharyngeal painFAERS: 3OFFSIDES
SIDER
US FAERS
52RestlessnessFAERS: 3US FAERS
53RhabdomyolysisFAERS: 3OFFSIDES
US FAERS
54TremorFAERS: 3US FAERS
55UrticariaFAERS: 3SIDER
US FAERS
56Abdominal Compartment SyndromeFAERS: 2US FAERS
57Abdominal PainFAERS: 2SIDER
US FAERS
58AcidosisFAERS: 2US FAERS
59AgeusiaFAERS: 2US FAERS
60Alanine Aminotransferase IncreasedFAERS: 2US FAERS
61AmnesiaFAERS: 2OFFSIDES
US FAERS
62AngerFAERS: 2OFFSIDES
US FAERS
63AngioedemaFAERS: 2SIDER
US FAERS
64Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
65Atrial FibrillationFAERS: 2US FAERS
66Blood amylase increasedFAERS: 2US FAERS
67Body height below normalFAERS: 2US FAERS
68Depressed Level of ConsciousnessFAERS: 2OFFSIDES
US FAERS
69Depressed moodFAERS: 2US FAERS
70DysphoniaFAERS: 2US FAERS
71EpilepsyFAERS: 2OFFSIDES
US FAERS
72EpistaxisFAERS: 2SIDER
US FAERS
73Feeling abnormalFAERS: 2SIDER
US FAERS
74HypotensionFAERS: 2US FAERS
75HypoxiaFAERS: 2OFFSIDES
US FAERS
76InfectionFAERS: 2SIDER
US FAERS
77MalaiseFAERS: 2US FAERS
78MeningitisFAERS: 2US FAERS
79Middle insomniaFAERS: 2US FAERS
80MyalgiaFAERS: 2SIDER
US FAERS
81NeutropeniaFAERS: 2US FAERS
82PalpitationsFAERS: 2US FAERS
83PneumonitisFAERS: 2US FAERS
84PneumothoraxFAERS: 2OFFSIDES
US FAERS
85Psychiatric symptomFAERS: 2OFFSIDES
US FAERS
86PyelocaliectasisFAERS: 2US FAERS
87Rash erythematousFAERS: 2US FAERS
88Sinus bradycardiaFAERS: 2US FAERS
89SinusitisFAERS: 2SIDER
US FAERS
90StrabismusFAERS: 2US FAERS
91Sudden deathFAERS: 2OFFSIDES
US FAERS
92Therapy cessationFAERS: 2US FAERS
93Thrombosis in deviceFAERS: 2US FAERS
94UnderweightFAERS: 2US FAERS
95Unresponsive to stimuliFAERS: 2US FAERS
96Visual ImpairmentFAERS: 2SIDER
US FAERS
97jaundiceFAERS: 2SIDER
US FAERS
98Adverse eventFAERS: 1OFFSIDES
US FAERS
99Altered state of consciousnessFAERS: 1OFFSIDES
US FAERS
100Anal abscessFAERS: 1US FAERS
101AnosmiaFAERS: 1US FAERS
102ArthralgiaFAERS: 1SIDER
US FAERS
103Audiogram abnormalFAERS: 1US FAERS
104Back PainFAERS: 1SIDER
US FAERS
105BlepharitisFAERS: 1US FAERS
106Blood creatinine increasedFAERS: 1US FAERS
107BradycardiaFAERS: 1US FAERS
108BronchiectasisFAERS: 1US FAERS
109BronchiolitisFAERS: 1US FAERS
110Cerebral disorderFAERS: 1US FAERS
111Cerebrovascular accidentFAERS: 1US FAERS
112Chest discomfortFAERS: 1US FAERS
113ChillsFAERS: 1US FAERS
114ColitisFAERS: 1US FAERS
115Congenital HypothyroidismFAERS: 1US FAERS
116ConstipationFAERS: 1US FAERS
117Conversion disorderFAERS: 1US FAERS
118Dacryostenosis congenitalFAERS: 1US FAERS
119Deep Vein ThrombosisFAERS: 1US FAERS
120DiplopiaFAERS: 1OFFSIDES
US FAERS
121Drug level increasedFAERS: 1US FAERS
122Duodenal ulcer perforationFAERS: 1US FAERS
123DysarthriaFAERS: 1US FAERS
124DysgeusiaFAERS: 1US FAERS
125Educational problemFAERS: 1US FAERS
126Escherichia sepsisFAERS: 1US FAERS
127Febrile NeutropeniaFAERS: 1US FAERS
128Flank PainFAERS: 1US FAERS
129FlushingFAERS: 1US FAERS
130FormicationFAERS: 1US FAERS
131GastroenteritisFAERS: 1US FAERS
132Guillain-Barre SyndromeFAERS: 1US FAERS
133HELLP SyndromeFAERS: 1US FAERS
134Hepatic EncephalopathyFAERS: 1US FAERS
135HepatomegalyFAERS: 1US FAERS
136Hepatorenal SyndromeFAERS: 1US FAERS
137HypersensitivityFAERS: 1SIDER
US FAERS
138Intentional product misuseFAERS: 1US FAERS
139IntertrigoFAERS: 1US FAERS
140LaryngitisFAERS: 1US FAERS
141LeptospirosisFAERS: 1US FAERS
142LethargyFAERS: 1US FAERS
143LeukocytosisFAERS: 1US FAERS
144Liver palpable subcostalFAERS: 1OFFSIDES
US FAERS
145Low birth weight babyFAERS: 1US FAERS
146LymphadenitisFAERS: 1US FAERS
147Macular degenerationFAERS: 1US FAERS
148Mental status changesFAERS: 1US FAERS
149Muscle tightnessFAERS: 1US FAERS
150Musculoskeletal PainFAERS: 1US FAERS
151Musculoskeletal chest painFAERS: 1US FAERS
152Myocardial InfarctionFAERS: 1US FAERS
153Neck PainFAERS: 1US FAERS
154Neonatal disorderFAERS: 1US FAERS
155Neonatal infectionFAERS: 1US FAERS
156NervousnessFAERS: 1US FAERS
157OligohydramniosFAERS: 1US FAERS
158PallorFAERS: 1US FAERS
159Panic DisorderFAERS: 1US FAERS
160PapuleFAERS: 1US FAERS
161ParanoiaFAERS: 1US FAERS
162PericarditisFAERS: 1US FAERS
163Personality ChangeFAERS: 1OFFSIDES
US FAERS
164PetechiaeFAERS: 1US FAERS
165Pre-EclampsiaFAERS: 1US FAERS
166PresyncopeFAERS: 1US FAERS
167Product blister packaging issueFAERS: 1US FAERS
168Product label issueFAERS: 1US FAERS
169Product packaging confusionFAERS: 1US FAERS
170Productive CoughFAERS: 1US FAERS
171Pulmonary function test decreasedFAERS: 1US FAERS
172Respiratory arrestFAERS: 1US FAERS
173RetchingFAERS: 1US FAERS
174Septic ShockFAERS: 1US FAERS
175Skin UlcerFAERS: 1US FAERS
176SomnolenceFAERS: 1US FAERS
177Spina Bifida OccultaFAERS: 1US FAERS
178StomatitisFAERS: 1US FAERS
179Supraventricular tachycardiaFAERS: 1OFFSIDES
US FAERS
180Therapeutic response changedFAERS: 1US FAERS
181Throat irritationFAERS: 1US FAERS
182Tongue exfoliationFAERS: 1US FAERS
183TonsillitisFAERS: 1US FAERS
184Toxic Epidermal NecrolysisFAERS: 1SIDER
US FAERS
185Transient psychosisFAERS: 1US FAERS
186Umbilical herniaFAERS: 1US FAERS
187Ventilation perfusion mismatchFAERS: 1US FAERS
188Weight decreasedFAERS: 1US FAERS
189treatment failureFAERS: 1US FAERS
190Abdominal tendernessOFFSIDES
191Abnormal visionOFFSIDES
192Accidental overdoseOFFSIDES
193AcheSIDER
194Acute bronchitisOFFSIDES
195Acute respiratory failureOFFSIDES
196Acute tonsillitisSIDER
197Alice in Wonderland SyndromeOFFSIDES
198Anaphylactic shockSIDER
199Anaphylactoid ReactionSIDER
200AnencephalyOFFSIDES
201Angina PectorisSIDER
202AngiomyolipomaOFFSIDES
203Angiotensin converting enzyme increasedOFFSIDES
204AnhedoniaOFFSIDES
205AnophthalmosOFFSIDES
206AnorexiaOFFSIDES
207Antinuclear antibody increasedOFFSIDES
208Asthma aggravatedSIDER
209AuraOFFSIDES
210Autoimmune thyroiditisOFFSIDES
211AutomatismOFFSIDES
212Autonomic neuropathyOFFSIDES
213Blood and lymphatic system disordersSIDER
214Blood creatine phosphokinase increasedOFFSIDES
215Blood lactate dehydrogenase increasedOFFSIDES
216Blood urea abnormalOFFSIDES
217Body TemperatureOFFSIDES
218Bone density decreasedOFFSIDES
219Bone marrow myelogram abnormalOFFSIDES
220Brain ContusionOFFSIDES
221Brain DeathOFFSIDES
222BruxismOFFSIDES
223Cardiac discomfortOFFSIDES
224Cardiac enzymes increasedOFFSIDES
225Cardioactive drug level increasedOFFSIDES
226CarotidyniaOFFSIDES
227Catheter sepsisOFFSIDES
228Cell DeathOFFSIDES
229ChokingOFFSIDES
230CholangiolitisOFFSIDES
231ChromaturiaOFFSIDES
232Chronic sinusitisOFFSIDES
233Circumstance or information capable of leading to medication errorOFFSIDES
234Coagulation factor VII level decreasedOFFSIDES
235Complications of maternal exposure to therapeutic drugsOFFSIDES
236ConfabulationOFFSIDES
237ConjunctivitisSIDER
238Delirium febrileOFFSIDES
239Denture wearerOFFSIDES
240DermatitisSIDER
241DermatomyositisOFFSIDES
242Diabetes MellitusSIDER
243DiarrheaOFFSIDES
244Disease ProgressionOFFSIDES
245Disseminated Intravascular CoagulationOFFSIDES
246Disseminated intravascular coagulation in newbornOFFSIDES
247Drug administration errorOFFSIDES
248Drug exposure via breast milkOFFSIDES
249DyscalculiaOFFSIDES
250DyslaliaOFFSIDES
251DyspepsiaSIDER
252Ear and labyrinth disordersSIDER
253Economic problemOFFSIDES
254Eczema allergic atopicSIDER
255Ejection Fraction DecreasedOFFSIDES
256Emotional disorderOFFSIDES
257EnterocolitisOFFSIDES
258Eosinophilic myocarditisOFFSIDES
259Erythema MultiformeOFFSIDES
SIDER
260Erythema NodosumOFFSIDES
261Eustachian tube disorderOFFSIDES
262Eye RednessSIDER
263Eye painSIDER
264Eyelid Function DisorderOFFSIDES
265Fat intoleranceOFFSIDES
266Febrile bone marrow aplasiaOFFSIDES
267FibromyalgiaOFFSIDES
268Gastric mucosal lesionOFFSIDES
269Gastrointestinal PainSIDER
270Genital erosionOFFSIDES
271Gingival HyperplasiaOFFSIDES
272Global AmnesiaOFFSIDES
273GlobulinuriaOFFSIDES
274GoiterOFFSIDES
275Granulocyte count decreasedOFFSIDES
276Hallucinations, mixedOFFSIDES
277Hay feverOFFSIDES
278Head BangingOFFSIDES
279Hemorrhagic colitisSIDER
280Hepatitis AOFFSIDES
281HepatitisSIDER
282HepatotoxicitySIDER
283Herpes simplex hepatitisOFFSIDES
284HypertransaminasaemiaOFFSIDES
285HypophagiaOFFSIDES
286Inappropriate affectOFFSIDES
287IncontinenceOFFSIDES
288Incorrect dose administeredOFFSIDES
289Infectious MononucleosisOFFSIDES
290InfestationSIDER
291Influenza serology positiveOFFSIDES
292Injury asphyxiationOFFSIDES
293Left atrial hypertrophyOFFSIDES
294Leukopenia neonatalOFFSIDES
295Life expectancy shortenedOFFSIDES
296LymphadenopathySIDER
297Lymphocyte count abnormalOFFSIDES
298Lymphocyte stimulation test positiveOFFSIDES
299Mastication disorderOFFSIDES
300Medical device removalOFFSIDES
301MetamorphopsiaOFFSIDES
302MoaningOFFSIDES
303MoroseOFFSIDES
304Musculoskeletal discomfortSIDER
305MyelitisOFFSIDES
306Myocardial fibrosisOFFSIDES
307NasopharyngitisSIDER
308Neonatal aspirationOFFSIDES
309Nephrotic SyndromeOFFSIDES
310Neurologic Manifestations15566030CTD
311Neutropenic colitisOFFSIDES
312NoduleOFFSIDES
313Oculomucocutaneous syndromeOFFSIDES
314Oropharyngeal discomfortSIDER
315Oropharyngeal plaqueOFFSIDES
316Orthomyxoviridae Infections28233349CTD
317OsteolysisOFFSIDES
318OsteopeniaOFFSIDES
319OverdoseOFFSIDES
320PROTHROMBIN TIMEOFFSIDES
321PanniculitisOFFSIDES
322Peritonsillar AbscessSIDER
323Pharyngeal StenosisOFFSIDES
324Physical disabilityOFFSIDES
325Pneumococcal sepsisOFFSIDES
326PoriomaniaOFFSIDES
327Postoperative wound complicationOFFSIDES
328Pre-existing condition improvedOFFSIDES
329Product tamperingOFFSIDES
330Prolonged expirationOFFSIDES
331Pulmonary hypertensive crisisOFFSIDES
332RalesOFFSIDES
333Rectal polypOFFSIDES
334Relapsing FeverOFFSIDES
335Retinal VasculitisOFFSIDES
336Rhinovirus infectionOFFSIDES
337SalmonellaOFFSIDES
338Sjogren's SyndromeOFFSIDES
339Sleep TalkingOFFSIDES
340SnoringOFFSIDES
341Sputum retentionOFFSIDES
342Staphylococcal Scalded Skin SyndromeOFFSIDES
343StaringOFFSIDES
344Status EpilepticusOFFSIDES
345StridorOFFSIDES
346Subcutaneous AbscessOFFSIDES
347SwellingSIDER
348TachyphreniaOFFSIDES
349Tarsal Tunnel SyndromeOFFSIDES
350Therapy non-responderOFFSIDES
351Tracheostomy malfunctionOFFSIDES
352Traumatic fractureOFFSIDES
353Trigeminal palsyOFFSIDES
354Troponin I increasedOFFSIDES
355Vaccination failureOFFSIDES
356Ventricular FlutterOFFSIDES
357VertigoSIDER
358Violence-related symptomOFFSIDES
359Viral labyrinthitisOFFSIDES
360Viral test positiveOFFSIDES
361Visual disturbanceOFFSIDES
SIDER
362muscle injuryOFFSIDES
363nervous system disorderSIDER
364pseudomembranous colitisSIDER
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