MetaADEDB 2.0 @ LMMD
lanreotide
(DEXPIBGCLCPUHE-UISHROKMSA-N)
Structure
SMILES
CC(=O)O.NCCCC[C@@H]1NC(=O)[C@H](NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](NC1=O)C(C)C)C(=O)N[C@H](C(=O)N)[C@H](O)C)NC(=O)[C@@H](Cc1ccc2c(c1)cccc2)N)Cc1c[nH]c2c1cccc2
Molecular Formula:
C56H73N11O12S2
Molecular Weight:
1156.380
Log P:
5.4392
Hydrogen Bond Acceptor:
24
Hydrogen Bond Donor:
14
TPSA:
442.98
CAS Number(s):
N/A
Synonym(s)
1.
lanreotide
2.
188Re-lanreotide
3.
2-naphthylalanyl-cyclo(cysteinyl-tyrosyl-tryptophyl-lysyl-valyl-cysteinyl)-threoninamide
4.
BIM 23014
5.
BIM 23014C
6.
BIM-23014
7.
DC 13-116
8.
DC-13-116
9.
DC13-116
10.
L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2-7)-disulfide
11.
Nal-cyclo(Cys-Tyr-Trp-Lys-Val-Cys)-Thr-NH2
12.
Nal-cyclo(Cys-Tyr-Trp-Lys-Val-Cys)Thr-NH2
13.
Somatulin
14.
Somatulina
15.
Somatuline
16.
lanreotide acetate
17.
lanreotide-SR
18.
naphthalenyl-cyclo(cysteinyl-tyrosyl-tryptophyl-lysyl-valyl-cysteinyl)threoninamide
19.
naphthyl-cyclo(Cys-Tyr-Trp-Lys-Val-Cys)Thr-NH2
External Link(s)
MeSHC060347
PubChem Compound6918010
CHEMBLCHEMBL1201184
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Injection site painFAERS: 118US FAERS
2Inappropriate schedule of drug administrationFAERS: 95US FAERS
3NauseaFAERS: 60US FAERS
4FatigueFAERS: 53US FAERS
5Injection site massFAERS: 47US FAERS
6MalaiseFAERS: 47US FAERS
7Abdominal PainFAERS: 44US FAERS
8HeadacheFAERS: 43US FAERS
9VomitingFAERS: 39US FAERS
10FlatulenceFAERS: 31US FAERS
11Disease ProgressionFAERS: 29US FAERS
12Drug ineffectiveFAERS: 28US FAERS
13PainFAERS: 26US FAERS
14DizzinessFAERS: 25US FAERS
15AstheniaFAERS: 22US FAERS
16ArthralgiaFAERS: 21US FAERS
17Incorrect route of drug administrationFAERS: 20US FAERS
18Weight decreasedFAERS: 20US FAERS
19AlopeciaFAERS: 19US FAERS
20Injection site noduleFAERS: 19US FAERS
21CholelithiasisFAERS: 18US FAERS
22Drug dose omissionFAERS: 18US FAERS
23Abdominal discomfortFAERS: 17US FAERS
24Feeling abnormalFAERS: 17US FAERS
25AnxietyFAERS: 13US FAERS
26Blood glucose increasedFAERS: 13US FAERS
27DehydrationFAERS: 13US FAERS
28Insulin-like growth factor increasedFAERS: 13US FAERS
29Adverse eventFAERS: 12US FAERS
30PneumoniaFAERS: 12US FAERS
31Product dose omissionFAERS: 12US FAERS
32FlushingFAERS: 11US FAERS
33Back PainFAERS: 10US FAERS
34Cerebrovascular accidentFAERS: 10US FAERS
35LethargyFAERS: 10US FAERS
36ConstipationFAERS: 9US FAERS
37General physical health deteriorationFAERS: 9US FAERS
38Injection site pruritusFAERS: 9US FAERS
39Chest PainFAERS: 8US FAERS
40Intestinal ObstructionFAERS: 8US FAERS
41Wrong technique in product usage processFAERS: 8US FAERS
42Blood growth hormone increasedFAERS: 7US FAERS
43Injection site bruisingFAERS: 7US FAERS
44Terminal stateFAERS: 7US FAERS
45Blood glucose decreasedFAERS: 6US FAERS
46BradycardiaFAERS: 6US FAERS
47Drug administration errorFAERS: 6US FAERS
48Feeling ColdFAERS: 6US FAERS
49MyalgiaFAERS: 6US FAERS
50Product use issueFAERS: 6US FAERS
51PruritusFAERS: 6US FAERS
52TremorFAERS: 6US FAERS
53AcromegalyFAERS: 5US FAERS
54CholestasisFAERS: 5US FAERS
55Cytolytic hepatitisFAERS: 5US FAERS
56Drug administered at inappropriate siteFAERS: 5US FAERS
57EructationFAERS: 5US FAERS
58Incorrect drug administration durationFAERS: 5US FAERS
59Injection site erythemaFAERS: 5US FAERS
60Malignant neoplasm progressionFAERS: 5US FAERS
61MetastasisFAERS: 5US FAERS
62Neck PainFAERS: 5US FAERS
63Needle issueFAERS: 5US FAERS
64PancreatitisFAERS: 5US FAERS
65SinusitisFAERS: 5US FAERS
66SomnolenceFAERS: 5US FAERS
67SyncopeFAERS: 5US FAERS
68Therapy cessationFAERS: 5US FAERS
69Unevaluable eventFAERS: 5US FAERS
70AbscessFAERS: 4US FAERS
71ArthritisFAERS: 4US FAERS
72Blood potassium decreasedFAERS: 4US FAERS
73ChillsFAERS: 4US FAERS
74DisorientationFAERS: 4US FAERS
75DyspepsiaFAERS: 4US FAERS
76HypersensitivityFAERS: 4US FAERS
77IleusFAERS: 4US FAERS
78Incorrect product storageFAERS: 4US FAERS
79Memory impairmentFAERS: 4US FAERS
80Musculoskeletal PainFAERS: 4US FAERS
81Myocardial InfarctionFAERS: 4US FAERS
82OverdoseFAERS: 4US FAERS
83PericarditisFAERS: 4US FAERS
84Peripheral swellingFAERS: 4US FAERS
85Post procedural complicationFAERS: 4US FAERS
86Urinary tract infectionFAERS: 4US FAERS
87UrticariaFAERS: 4US FAERS
88VertigoFAERS: 4US FAERS
89Alanine Aminotransferase IncreasedFAERS: 3US FAERS
90Blood glucose fluctuationFAERS: 3US FAERS
91Chest discomfortFAERS: 3US FAERS
92CholecystitisFAERS: 3US FAERS
93Cold sweatFAERS: 3US FAERS
94Depressed Level of ConsciousnessFAERS: 3US FAERS
95Diabetes MellitusFAERS: 3US FAERS
96DiscomfortFAERS: 3US FAERS
97Drug ineffective for unapproved indicationFAERS: 3US FAERS
98DyscheziaFAERS: 3US FAERS
99Eye painFAERS: 3US FAERS
100Frustration tolerance decreasedFAERS: 3US FAERS
101Hospice CareFAERS: 3US FAERS
102Incorrect storage of drugFAERS: 3US FAERS
103InfluenzaFAERS: 3US FAERS
104Injection Site ReactionFAERS: 3US FAERS
105Injection site abscessFAERS: 3US FAERS
106Injection site discomfortFAERS: 3US FAERS
107Injection site granulomaFAERS: 3US FAERS
108Injection site scarFAERS: 3US FAERS
109Injection site warmthFAERS: 3US FAERS
110Lack of injection site rotationFAERS: 3US FAERS
111MalnutritionFAERS: 3US FAERS
112NasopharyngitisFAERS: 3US FAERS
113Night sweatsFAERS: 3US FAERS
114NoduleFAERS: 3US FAERS
115PallorFAERS: 3US FAERS
116PalpitationsFAERS: 3US FAERS
117PancytopeniaFAERS: 3US FAERS
118Prescribed overdoseFAERS: 3US FAERS
119Product quality issueFAERS: 3US FAERS
120Spinal column stenosisFAERS: 3US FAERS
121Therapeutic response unexpectedFAERS: 3US FAERS
122ThrombocytopeniaFAERS: 3US FAERS
123AbasiaFAERS: 2US FAERS
124Activities of daily living impairedFAERS: 2US FAERS
125AmnesiaFAERS: 2US FAERS
126AngioedemaFAERS: 2US FAERS
127AscitesFAERS: 2US FAERS
128Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
129AsthmaFAERS: 2US FAERS
130Atrial FibrillationFAERS: 2US FAERS
131BedriddenFAERS: 2US FAERS
132BlindnessFAERS: 2US FAERS
133Blood alkaline phosphatase increasedFAERS: 2US FAERS
134Bone density decreasedFAERS: 2US FAERS
135CholangitisFAERS: 2US FAERS
136ColitisFAERS: 2US FAERS
137CryingFAERS: 2US FAERS
138CystitisFAERS: 2US FAERS
139CystFAERS: 2US FAERS
140Disseminated Intravascular CoagulationFAERS: 2US FAERS
141DysarthriaFAERS: 2US FAERS
142EpistaxisFAERS: 2US FAERS
143ErythemaFAERS: 2US FAERS
144Gamma-Glutamyltransferase IncreasedFAERS: 2US FAERS
145Gastrointestinal PainFAERS: 2US FAERS
146Gastrointestinal infectionFAERS: 2US FAERS
147GranulomaFAERS: 2US FAERS
148HerniaFAERS: 2US FAERS
149Hormone level abnormalFAERS: 2US FAERS
150HungerFAERS: 2US FAERS
151HypotensionFAERS: 2US FAERS
152Impaired work abilityFAERS: 2US FAERS
153Inappropriate schedule of product administrationFAERS: 2US FAERS
154Incorrect route of product administrationFAERS: 2US FAERS
155InfectionFAERS: 2US FAERS
156InflammationFAERS: 2US FAERS
157Injection site infectionFAERS: 2US FAERS
158Injection site necrosisFAERS: 2US FAERS
159Joint stiffnessFAERS: 2US FAERS
160Joint swellingFAERS: 2US FAERS
161LaryngitisFAERS: 2US FAERS
162LymphadenopathyFAERS: 2US FAERS
163Magnesium DeficiencyFAERS: 2US FAERS
164MenorrhagiaFAERS: 2US FAERS
165MicrolithiasisFAERS: 2US FAERS
166Musculoskeletal chest painFAERS: 2US FAERS
167NephrolithiasisFAERS: 2US FAERS
168Nerve injuryFAERS: 2US FAERS
169Poor quality sleepFAERS: 2US FAERS
170PresyncopeFAERS: 2US FAERS
171Product physical consistency issueFAERS: 2US FAERS
172Product storage errorFAERS: 2US FAERS
173Quality of life decreasedFAERS: 2US FAERS
174SciaticaFAERS: 2US FAERS
175Septic ShockFAERS: 2US FAERS
176Serotonin SyndromeFAERS: 2US FAERS
177ThirstFAERS: 2US FAERS
178ThrombosisFAERS: 2US FAERS
179jaundiceFAERS: 2US FAERS
180Abdominal adhesionsFAERS: 1US FAERS
181Abdominal massFAERS: 1US FAERS
182Accidental overdoseFAERS: 1US FAERS
183Acral overgrowthFAERS: 1US FAERS
184Administration related reactionFAERS: 1US FAERS
185AgeusiaFAERS: 1US FAERS
186Altered state of consciousnessFAERS: 1US FAERS
187Amylase increasedFAERS: 1US FAERS
188AngerFAERS: 1US FAERS
189Aortic AneurysmFAERS: 1US FAERS
190ApathyFAERS: 1US FAERS
191AphagiaFAERS: 1US FAERS
192AphoniaFAERS: 1US FAERS
193ArthropathyFAERS: 1US FAERS
194Atrioventricular BlockFAERS: 1US FAERS
195Biliary ColicFAERS: 1US FAERS
196Biliary FistulaFAERS: 1US FAERS
197Bladder painFAERS: 1US FAERS
198Blighted ovumFAERS: 1US FAERS
199Blood cholesterol increasedFAERS: 1US FAERS
200Blood cortisol increasedFAERS: 1US FAERS
201Blood count abnormalFAERS: 1US FAERS
202Blood glucose abnormalFAERS: 1US FAERS
203Blood growth hormone abnormalFAERS: 1US FAERS
204Blood growth hormone decreasedFAERS: 1US FAERS
205Blood homocysteine increasedFAERS: 1US FAERS
206Blood pressure fluctuationFAERS: 1US FAERS
207Blood prolactin increasedFAERS: 1US FAERS
208Blood thyroid stimulating hormone decreasedFAERS: 1US FAERS
209Blood triglycerides increasedFAERS: 1US FAERS
210Bone density abnormalFAERS: 1US FAERS
211Bone painFAERS: 1US FAERS
212Bowel movement irregularityFAERS: 1US FAERS
213Burning sensationFAERS: 1US FAERS
214Cancer PainFAERS: 1US FAERS
215Carcinoid Heart DiseaseFAERS: 1US FAERS
216Carcinoid crisisFAERS: 1US FAERS
217Cardiac ArrestFAERS: 1US FAERS
218CellulitisFAERS: 1US FAERS
219Cerebral disorderFAERS: 1US FAERS
220Cytoreductive SurgeryFAERS: 1US FAERS
221Dark circles under eyesFAERS: 1US FAERS
222DeafnessFAERS: 1US FAERS
223Deep Vein ThrombosisFAERS: 1US FAERS
224Depressed moodFAERS: 1US FAERS
225Device difficult to useFAERS: 1US FAERS
226Device malfunctionFAERS: 1US FAERS
227Device use errorFAERS: 1US FAERS
228Diabetes mellitus inadequate controlFAERS: 1US FAERS
229Diabetic KetoacidosisFAERS: 1US FAERS
230DiplegiaFAERS: 1US FAERS
231Drug DependenceFAERS: 1US FAERS
232Drug administered to patient of inappropriate ageFAERS: 1US FAERS
233Drug effect delayedFAERS: 1US FAERS
234Drug effect incompleteFAERS: 1US FAERS
235Drug prescribing errorFAERS: 1US FAERS
236DuodenitisFAERS: 1US FAERS
237DysgeusiaFAERS: 1US FAERS
238Emergency CareFAERS: 1US FAERS
239Emotional distressFAERS: 1US FAERS
240EndocarditisFAERS: 1US FAERS
241EpilepsyFAERS: 1US FAERS
242ExcoriationFAERS: 1US FAERS
243Exposure during breast feedingFAERS: 1US FAERS
244Eye irritationFAERS: 1US FAERS
245Fat necrosisFAERS: 1US FAERS
246Feeding tube complicationFAERS: 1US FAERS
247Feeling jitteryFAERS: 1US FAERS
248FibromyalgiaFAERS: 1US FAERS
249Gait inabilityFAERS: 1US FAERS
250Gallbladder painFAERS: 1US FAERS
251GastritisFAERS: 1US FAERS
252Gastroenteritis norovirusFAERS: 1US FAERS
253GastroenteritisFAERS: 1US FAERS
254Gastrointestinal obstructionFAERS: 1US FAERS
255Gastrointestinal sounds abnormalFAERS: 1US FAERS
256Gastrointestinal stoma complicationFAERS: 1US FAERS
257General physical condition abnormalFAERS: 1US FAERS
258Hepatic EncephalopathyFAERS: 1US FAERS
259Hepatic artery embolismFAERS: 1US FAERS
260Hepatic cyst infectionFAERS: 1US FAERS
261HyperchlorhydriaFAERS: 1US FAERS
262HyperlipasaemiaFAERS: 1US FAERS
263HyperparathyroidismFAERS: 1US FAERS
264Hyperplastic cholecystopathyFAERS: 1US FAERS
265HypersomniaFAERS: 1US FAERS
266HypersplenismFAERS: 1US FAERS
267HypokinesiaFAERS: 1US FAERS
268HypophagiaFAERS: 1US FAERS
269Incorrect dose administeredFAERS: 1US FAERS
270Incorrect drug administration rateFAERS: 1US FAERS
271Incorrect product administration durationFAERS: 1US FAERS
272Inflammatory marker increasedFAERS: 1US FAERS
273Injection site extravasationFAERS: 1US FAERS
274Injection site inflammationFAERS: 1US FAERS
275Injection site injuryFAERS: 1US FAERS
276Injection site urticariaFAERS: 1US FAERS
277Insulin-like growth factor decreasedFAERS: 1US FAERS
278Intentional product misuseFAERS: 1US FAERS
279Intercepted drug dispensing errorFAERS: 1US FAERS
280Intestinal resectionFAERS: 1US FAERS
281LeukopeniaFAERS: 1US FAERS
282Lip swellingFAERS: 1US FAERS
283Lipase increasedFAERS: 1US FAERS
284Liver AbscessFAERS: 1US FAERS
285Loss of personal independence in daily activitiesFAERS: 1US FAERS
286Low density lipoprotein increasedFAERS: 1US FAERS
287Lower respiratory tract infectionFAERS: 1US FAERS
288MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
289Macular degenerationFAERS: 1US FAERS
290MalabsorptionFAERS: 1US FAERS
291Male Orgasmic DisorderFAERS: 1US FAERS
292Mastication disorderFAERS: 1US FAERS
293Maternal exposure during pregnancyFAERS: 1US FAERS
294Meniscus injuryFAERS: 1US FAERS
295Metastatic NeoplasmFAERS: 1US FAERS
296Mineral deficiencyFAERS: 1US FAERS
297Mood swingsFAERS: 1US FAERS
298Muscle FatigueFAERS: 1US FAERS
299Muscle abscessFAERS: 1US FAERS
300Muscle strainFAERS: 1US FAERS
301Musculoskeletal stiffnessFAERS: 1US FAERS
302Nervous system neoplasm surgeryFAERS: 1US FAERS
303NervousnessFAERS: 1US FAERS
304NeutropeniaFAERS: 1US FAERS
305ObstructionFAERS: 1US FAERS
306Oropharyngeal painFAERS: 1US FAERS
307OsteodystrophyFAERS: 1US FAERS
308OsteoporosisFAERS: 1US FAERS
309Pancreatic carcinomaFAERS: 1US FAERS
310ParaplegiaFAERS: 1US FAERS
311PetechiaeFAERS: 1US FAERS
312PharyngitisFAERS: 1US FAERS
313Platelet count abnormalFAERS: 1US FAERS
314Pneumatosis intestinalisFAERS: 1US FAERS
315PolyneuropathyFAERS: 1US FAERS
316Post procedural bile leakFAERS: 1US FAERS
317PregnancyFAERS: 1US FAERS
318Product administered at inappropriate siteFAERS: 1US FAERS
319Product depositFAERS: 1US FAERS
320Product leakageFAERS: 1US FAERS
321Product physical issueFAERS: 1US FAERS
322Productive CoughFAERS: 1US FAERS
323Rectal tenesmusFAERS: 1US FAERS
324Respiratory FailureFAERS: 1US FAERS
325RestlessnessFAERS: 1US FAERS
326Retinal DetachmentFAERS: 1US FAERS
327RhabdomyolysisFAERS: 1US FAERS
328Rheumatoid ArthritisFAERS: 1US FAERS
329ScabFAERS: 1US FAERS
330Sinus headacheFAERS: 1US FAERS
331Skeletal injuryFAERS: 1US FAERS
332Skin hypertrophyFAERS: 1US FAERS
333Skin irritationFAERS: 1US FAERS
334Spinal fusion surgeryFAERS: 1US FAERS
335SplenomegalyFAERS: 1US FAERS
336SteatohepatitisFAERS: 1US FAERS
337Subcutaneous drug absorption impairedFAERS: 1US FAERS
338SubileusFAERS: 1US FAERS
339SwellingFAERS: 1US FAERS
340Symptom recurrenceFAERS: 1US FAERS
341TachycardiaFAERS: 1US FAERS
342Temperature intoleranceFAERS: 1US FAERS
343Therapeutic response changedFAERS: 1US FAERS
344ThyroidectomyFAERS: 1US FAERS
345TinnitusFAERS: 1US FAERS
346ToothacheFAERS: 1US FAERS
347Toxicity to various agentsFAERS: 1US FAERS
348Transaminases increasedFAERS: 1US FAERS
349TrismusFAERS: 1US FAERS
350Upper respiratory tract congestionFAERS: 1US FAERS
351Urine output increasedFAERS: 1US FAERS
352Very low density lipoprotein increasedFAERS: 1US FAERS
353Vital functions abnormalFAERS: 1US FAERS
354Vitamin A DeficiencyFAERS: 1US FAERS
355Vitamin D DeficiencyFAERS: 1US FAERS
356Vitamin K DeficiencyFAERS: 1US FAERS
357Vitreous degenerationFAERS: 1US FAERS
358WheezingFAERS: 1US FAERS
359muscle injuryFAERS: 1US FAERS
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