MetaADEDB 2.0 @ LMMD
Insulin Lispro
(AIRYAONNMGRCGJ-FHFVDXKLSA-N)
Structure
SMILES
NCCCC[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)[C@H](O)C)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H]([C@H](CC)C)NC(=O)CN)CCC(=O)O)CCC(=O)N)C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)C(C)C)CC(C)C)Cc1ccc(cc1)O)CC(C)C)C)CCC(=O)O)C(C)C)CC(C)C)Cc1c[nH]cn1)CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc1ccccc1)N)CC(=O)N)CCC(=O)N)Cc1c[nH]cn1)CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)[C@H](CC)C)CO)[C@H](O)C)C(=O)N[C@H](C(=O)O)CC(=O)N)CCC(=O)O)CCCNC(=N)N)Cc1ccccc1)Cc1ccc(cc1)O
Molecular Formula:
C257H383N65O77S6
Molecular Weight:
5807.570
Log P:
5.2078
Hydrogen Bond Acceptor:
146
Hydrogen Bond Donor:
78
TPSA:
2450.87
CAS Number(s):
N/A
Synonym(s)
1.
Insulin Lispro
2.
28(B)-Lys-29(B)-Pro-Insulin
3.
28(B)-Lysine-29(B)-Prolineinsulin
4.
Humalog
5.
Humalog Kwikpen
6.
Insulin, Lys(28B)-Pro(29B)-
7.
Insulin, Lysyl(28B)-Prolyl(28B)-
8.
LYSPRO
9.
Lispro
10.
Kwikpen, Humalog
11.
Lispro, Insulin
External Link(s)
MeSHD061268
PubChem Compound118984450
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Blood glucose increasedFAERS: 30US FAERS
2Product dose omissionFAERS: 11US FAERS
3Drug ineffectiveFAERS: 10US FAERS
4Device operational issueFAERS: 7US FAERS
5Blood glucose decreasedFAERS: 5US FAERS
6Blood glucose fluctuationFAERS: 5US FAERS
7NauseaFAERS: 5US FAERS
8Blood glucose abnormalFAERS: 4US FAERS
9Injection site painFAERS: 4US FAERS
10Product storage errorFAERS: 4US FAERS
11Product use issueFAERS: 4US FAERS
12Diabetes mellitus inadequate controlFAERS: 3US FAERS
13DizzinessFAERS: 3US FAERS
14Inappropriate schedule of product administrationFAERS: 3US FAERS
15Unevaluable eventFAERS: 3US FAERS
16Visual ImpairmentFAERS: 3US FAERS
17Device leakageFAERS: 2US FAERS
18Diabetic KetoacidosisFAERS: 2US FAERS
19Incorrect dose administered by deviceFAERS: 2US FAERS
20Incorrect dose administeredFAERS: 2US FAERS
21OverdoseFAERS: 2US FAERS
22Product container issueFAERS: 2US FAERS
23Product quality issueFAERS: 2US FAERS
24Product use complaintFAERS: 2US FAERS
25VomitingFAERS: 2US FAERS
26Weight decreasedFAERS: 2US FAERS
27Wrong technique in product usage processFAERS: 2US FAERS
28Abdominal PainFAERS: 1US FAERS
29Accidental overdoseFAERS: 1US FAERS
30Adverse eventFAERS: 1US FAERS
31AgitationFAERS: 1US FAERS
32ArthralgiaFAERS: 1US FAERS
33Blood ketone body increasedFAERS: 1US FAERS
34Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
35DeafnessFAERS: 1US FAERS
36DehydrationFAERS: 1US FAERS
37DementiaFAERS: 1US FAERS
38Device breakageFAERS: 1US FAERS
39Device dispensing errorFAERS: 1US FAERS
40DiscomfortFAERS: 1US FAERS
41Drug dispensing errorFAERS: 1US FAERS
42Drug dose omissionFAERS: 1US FAERS
43Drug exposure during pregnancyFAERS: 1US FAERS
44Drug exposure via breast milkFAERS: 1US FAERS
45HeadacheFAERS: 1US FAERS
46HyperphagiaFAERS: 1US FAERS
47HypersensitivityFAERS: 1US FAERS
48HypophagiaFAERS: 1US FAERS
49Inappropriate schedule of drug administrationFAERS: 1US FAERS
50Incorrect dose administered by productFAERS: 1US FAERS
51Injection site extravasationFAERS: 1US FAERS
52Injection site pruritusFAERS: 1US FAERS
53Injection site scarFAERS: 1US FAERS
54Intentional product use issueFAERS: 1US FAERS
55KetoacidosisFAERS: 1US FAERS
56Ligament ruptureFAERS: 1US FAERS
57MalaiseFAERS: 1US FAERS
58NocturiaFAERS: 1US FAERS
59PalpitationsFAERS: 1US FAERS
60Pharyngeal swellingFAERS: 1US FAERS
61PneumoniaFAERS: 1US FAERS
62PolydipsiaFAERS: 1US FAERS
63Product contamination physicalFAERS: 1US FAERS
64Product measured potency issueFAERS: 1US FAERS
65Product selection errorFAERS: 1US FAERS
66Product supply issueFAERS: 1US FAERS
67PruritusFAERS: 1US FAERS
68Respiratory FailureFAERS: 1US FAERS
69Sinus TachycardiaFAERS: 1US FAERS
70SoporFAERS: 1US FAERS
71StillbirthFAERS: 1US FAERS
72Suicide attemptFAERS: 1US FAERS
73SyncopeFAERS: 1US FAERS
74Syringe issueFAERS: 1US FAERS
75TinnitusFAERS: 1US FAERS
76TremorFAERS: 1US FAERS
77Weight decrease neonatalFAERS: 1US FAERS
78treatment failureFAERS: 1US FAERS
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