MetaADEDB 2.0 @ LMMD
Dipyrone
(DJGAAPFSPWAYTJ-UHFFFAOYSA-M)
Structure
SMILES
CN(c1c(C)n(n(c1=O)c1ccccc1)C)CS(=O)(=O)[O-].[Na+]
Molecular Formula:
C13H16N3NaO4S
Molecular Weight:
333.339
Log P:
1.5041
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
0
TPSA:
95.75
CAS Number(s):
68-89-3; 5907-38-0
Synonym(s)
1.
Dipyrone
2.
Metamizole
3.
Methampyrone
4.
Noramidopyrine Methanesulfonate
5.
Algopyrin
6.
Analgin
7.
Biopyrin
8.
Dipyronium
9.
Metamizol
10.
Metamizole Sodium
11.
Methamizole
12.
Narone
13.
Noramidopyrine Methanesulfonate Sodium
14.
Normelubrine
15.
Novalgetol
16.
Novalgin
17.
Novamidazophen
18.
Novaminsulfone
19.
Optalgin
20.
Pyralgin
21.
Sulpyrin
22.
Sulpyrine
External Link(s)
MeSHD004177
PubChem Compound522325
ChEBI59033
CHEMBLCHEMBL487894
KEGGdr:D08190
Therapeutic Target DatabaseD0K9LD
D06JRD
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1OverdoseFAERS: 60US FAERS
2Accidental overdoseFAERS: 33OFFSIDES
US FAERS
3Hepatic necrosisFAERS: 28US FAERS
4CholestasisFAERS: 2712445177CTD
US FAERS
5Drug ineffectiveFAERS: 21US FAERS
6VomitingFAERS: 18US FAERS
7Toxicity to various agentsFAERS: 17US FAERS
8HypotensionFAERS: 14US FAERS
9Alanine Aminotransferase IncreasedFAERS: 12OFFSIDES
US FAERS
10Metabolic acidosisFAERS: 12OFFSIDES
US FAERS
11Aspartate Aminotransferase IncreasedFAERS: 11US FAERS
12Incorrect dose administeredFAERS: 8US FAERS
13NauseaFAERS: 8OFFSIDES
US FAERS
14UrticariaFAERS: 812396961CTD
US FAERS
15Abdominal PainFAERS: 7OFFSIDES
US FAERS
16Blood glucose increasedFAERS: 7US FAERS
17HepatotoxicityFAERS: 7OFFSIDES
US FAERS
18ErythemaFAERS: 6US FAERS
19General physical health deteriorationFAERS: 6OFFSIDES
US FAERS
20Suicide attemptFAERS: 6US FAERS
21Drug effect incompleteFAERS: 5US FAERS
22Hepatic EncephalopathyFAERS: 5US FAERS
23Stevens-Johnson SyndromeFAERS: 5OFFSIDES
US FAERS
24jaundiceFAERS: 5US FAERS
25AgitationFAERS: 4US FAERS
26Blood pH decreasedFAERS: 4US FAERS
27DehydrationFAERS: 4OFFSIDES
US FAERS
28Drug abuseFAERS: 4US FAERS
29Exposure during breast feedingFAERS: 4US FAERS
30HypoxiaFAERS: 4US FAERS
31MalaiseFAERS: 4US FAERS
32Respiratory FailureFAERS: 4OFFSIDES
US FAERS
33SomnolenceFAERS: 4US FAERS
34Toxic Epidermal NecrolysisFAERS: 4US FAERS
35Unresponsive to stimuliFAERS: 4US FAERS
36Accidental underdoseFAERS: 3US FAERS
37Cardiac ArrestFAERS: 3US FAERS
38Depressed Level of ConsciousnessFAERS: 3US FAERS
39Drug dispensing errorFAERS: 3US FAERS
40HypersensitivityFAERS: 3US FAERS
41Medication ErrorFAERS: 3US FAERS
42Mental status changesFAERS: 3US FAERS
43Myocardial InfarctionFAERS: 3US FAERS
44NystagmusFAERS: 3US FAERS
45Prescribed overdoseFAERS: 3US FAERS
46SepsisFAERS: 3US FAERS
47TachycardiaFAERS: 3US FAERS
48Ammonia increasedFAERS: 2US FAERS
49Amylase increasedFAERS: 2US FAERS
50Analgesic drug level above therapeuticFAERS: 2US FAERS
51AngioedemaFAERS: 2US FAERS
52AnxietyFAERS: 2US FAERS
53ArthralgiaFAERS: 2US FAERS
54Blood creatine phosphokinase increasedFAERS: 2US FAERS
55Blood glucose decreasedFAERS: 2US FAERS
56Blood lactate dehydrogenase increasedFAERS: 2OFFSIDES
US FAERS
57Brain DeathFAERS: 2US FAERS
58BronchiolitisFAERS: 2US FAERS
59CardiotoxicityFAERS: 2US FAERS
60Drug level increasedFAERS: 2US FAERS
61Drug toxicityFAERS: 2US FAERS
62EosinophiliaFAERS: 2US FAERS
63FatigueFAERS: 2US FAERS
64FlushingFAERS: 2US FAERS
65HeadacheFAERS: 27954762CTD
US FAERS
66HepatomegalyFAERS: 2US FAERS
67Intentional self-injuryFAERS: 2US FAERS
68LethargyFAERS: 2US FAERS
69Liver transplant rejectionFAERS: 2US FAERS
70MydriasisFAERS: 2US FAERS
71NeutropeniaFAERS: 2US FAERS
72No adverse eventFAERS: 2US FAERS
73OliguriaFAERS: 2US FAERS
74PainFAERS: 2

View details

2378946
9592021
11794927
12063090
14598202
19617648
23872152
 		CTD
US FAERS
75Post procedural complicationFAERS: 2US FAERS
76Refusal of treatment by relativeFAERS: 2US FAERS
77Renal tubular necrosisFAERS: 2US FAERS
78Respiratory distressFAERS: 2US FAERS
79Respiratory syncytial virus bronchiolitisFAERS: 2US FAERS
80Respiratory syncytial virus test positiveFAERS: 2US FAERS
81Sinus TachycardiaFAERS: 2US FAERS
82ThrombocytopeniaFAERS: 2US FAERS
83WheezingFAERS: 2US FAERS
84Accidental deathFAERS: 1US FAERS
85Accidental drug intake by childFAERS: 1US FAERS
86Accidental exposure to productFAERS: 1US FAERS
87Accidental exposureFAERS: 1US FAERS
88AcidosisFAERS: 1US FAERS
89AgranulocytosisFAERS: 13747087CTD
US FAERS
90Amino acid level decreasedFAERS: 1US FAERS
91Analgesic drug level increasedFAERS: 1US FAERS
92Anaphylactic shockFAERS: 1US FAERS
93Angina PectorisFAERS: 1US FAERS
94AscitesFAERS: 1OFFSIDES
US FAERS
95AspergillosisFAERS: 1US FAERS
96AtelectasisFAERS: 1US FAERS
97Biopsy liver abnormalFAERS: 1US FAERS
98Blood alkaline phosphatase increasedFAERS: 1US FAERS
99Blood amylase increasedFAERS: 1US FAERS
100Blood chloride increasedFAERS: 1US FAERS
101Blood creatinine increasedFAERS: 1OFFSIDES
US FAERS
102Blood electrolytes abnormalFAERS: 1US FAERS
103Blood pH increasedFAERS: 1US FAERS
104Blood phosphorus decreasedFAERS: 1US FAERS
105Blood potassium decreasedFAERS: 1OFFSIDES
US FAERS
106Blood sodium decreasedFAERS: 1US FAERS
107Blood sodium increasedFAERS: 1US FAERS
108BronchiectasisFAERS: 1US FAERS
109BronchospasmFAERS: 1US FAERS
110CatatoniaFAERS: 1US FAERS
111Cerebral InfarctionFAERS: 1US FAERS
112Chest PainFAERS: 1US FAERS
113ChillsFAERS: 1US FAERS
114ClonusFAERS: 1US FAERS
115Coma scale abnormalFAERS: 1US FAERS
116Conjunctival pallorFAERS: 1US FAERS
117Cytolytic hepatitisFAERS: 1US FAERS
118Depressed moodFAERS: 1US FAERS
119Diabetes InsipidusFAERS: 1US FAERS
120Diabetic KetoacidosisFAERS: 1US FAERS
121Disease complicationFAERS: 1US FAERS
122DizzinessFAERS: 1US FAERS
123Drug administered to patient of inappropriate ageFAERS: 1US FAERS
124Drug clearance increasedFAERS: 1US FAERS
125Drug level above therapeuticFAERS: 1US FAERS
126Drug prescribing errorFAERS: 1OFFSIDES
US FAERS
127Drug screen positiveFAERS: 1US FAERS
128Electrolyte imbalanceFAERS: 1US FAERS
129Fat necrosisFAERS: 1US FAERS
130Flank PainFAERS: 1US FAERS
131FlatulenceFAERS: 1US FAERS
132Gastrointestinal sounds abnormalFAERS: 1US FAERS
133HyperreflexiaFAERS: 1US FAERS
134HypertransaminasaemiaFAERS: 1US FAERS
135HypophagiaFAERS: 1US FAERS
136HyporeflexiaFAERS: 1US FAERS
137Incorrect route of drug administrationFAERS: 1US FAERS
138InfectionFAERS: 1OFFSIDES
US FAERS
139Intentional drug misuseFAERS: 1US FAERS
140Joint swellingFAERS: 1US FAERS
141KetonuriaFAERS: 1US FAERS
142KetosisFAERS: 1US FAERS
143Lactate pyruvate ratio increasedFAERS: 1US FAERS
144Leukocytoclastic vasculitisFAERS: 1US FAERS
145LeukocytosisFAERS: 1US FAERS
146LeukopeniaFAERS: 1US FAERS
147Lip swellingFAERS: 1US FAERS
148Livedo ReticularisFAERS: 1US FAERS
149Lymph node palpableFAERS: 1US FAERS
150Milk soy protein intoleranceFAERS: 1US FAERS
151Multiple drug overdoseFAERS: 1US FAERS
152NervousnessFAERS: 1US FAERS
153Neurological decompensationFAERS: 1US FAERS
154Ocular vascular disorderFAERS: 1US FAERS
155PCO2 decreasedFAERS: 1US FAERS
156PallorFAERS: 1US FAERS
157PancytopeniaFAERS: 1US FAERS
158PapuleFAERS: 1US FAERS
159Perianal erythemaFAERS: 1US FAERS
160Pharmaceutical product complaintFAERS: 1US FAERS
161PneumoniaFAERS: 121429049CTD
US FAERS
162PneumothoraxFAERS: 1US FAERS
163PoisoningFAERS: 1US FAERS
164PolyuriaFAERS: 1US FAERS
165Poor quality sleepFAERS: 1US FAERS
166PresyncopeFAERS: 1US FAERS
167Product formulation issueFAERS: 1US FAERS
168Product packaging issueFAERS: 1US FAERS
169Product quality issueFAERS: 1US FAERS
170Productive CoughFAERS: 1US FAERS
171Propofol Infusion SyndromeFAERS: 1US FAERS
172PruritusFAERS: 1US FAERS
173Pulmonary FibrosisFAERS: 1US FAERS
174Pulmonary arterial pressure increasedFAERS: 1US FAERS
175Pulmonary vascular disorderFAERS: 1US FAERS
176PurpuraFAERS: 1US FAERS
177Quality of life decreasedFAERS: 1US FAERS
178Reaction to drug excipientsFAERS: 1US FAERS
179Renal tubular disorderFAERS: 1OFFSIDES
US FAERS
180Respiratory arrestFAERS: 1US FAERS
181RhabdomyolysisFAERS: 1US FAERS
182ScreamingFAERS: 1US FAERS
183Septic embolusFAERS: 1US FAERS
184ShockFAERS: 1US FAERS
185Similar reaction on previous exposure to drugFAERS: 1US FAERS
186Skin tightnessFAERS: 1US FAERS
187Staphylococcus test positiveFAERS: 1US FAERS
188StressFAERS: 1US FAERS
189StuporFAERS: 1US FAERS
190Thermal burnFAERS: 1US FAERS
191Thrombocytopenic purpuraFAERS: 1US FAERS
192TinnitusFAERS: 1US FAERS
193Toxicologic test abnormalFAERS: 1US FAERS
194Transaminases increasedFAERS: 1OFFSIDES
US FAERS
195Ventricular hypertrophyFAERS: 1US FAERS
196Weaning failureFAERS: 1US FAERS
197Wrong drug administeredFAERS: 1US FAERS
198nervous system disorderFAERS: 1US FAERS
199AbscessOFFSIDES
200Acute myocardial infarctionOFFSIDES
201Acute respiratory failureOFFSIDES
202AgraphiaOFFSIDES
203Anal FissureOFFSIDES
204AnosmiaOFFSIDES
205Arterial InjuryOFFSIDES
206Arterial thrombosisOFFSIDES
207ArthropathyOFFSIDES
208AsphyxiaOFFSIDES
209Autoimmune thrombocytopeniaOFFSIDES
210Bile Duct StenosisOFFSIDES
211Bile duct necrosisOFFSIDES
212BlepharoptosisOFFSIDES
213Blood albumin decreasedOFFSIDES
214Blood antidiuretic hormone decreasedOFFSIDES
215Blood osmolarity decreasedOFFSIDES
216Blood phosphorus increasedOFFSIDES
217Blood sodiumOFFSIDES
218Blood thyroid stimulating hormone increasedOFFSIDES
219Blood urea increasedOFFSIDES
220Bone density decreasedOFFSIDES
221Bone erosionOFFSIDES
222Bone painOFFSIDES
223Brain natriuretic peptide increasedOFFSIDES
224Bulbar palsyOFFSIDES
225Cardioactive drug level increasedOFFSIDES
226Chemical and Drug Induced Liver Injury12445177CTD
227Chronic left ventricular failureOFFSIDES
228Clostridium difficile colitisOFFSIDES
229Congenital tricuspid valve incompetenceOFFSIDES
230Conjunctival depositOFFSIDES
231Corneal ScarOFFSIDES
232CyanosisOFFSIDES
233Dental abscessOFFSIDES
234Depression suicidalOFFSIDES
235DiarrheaOFFSIDES
236Diastolic dysfunctionOFFSIDES
237Disseminated Intravascular CoagulationOFFSIDES
238DrowsinessOFFSIDES
239Drug Eruptions12396961CTD
240Drug administration errorOFFSIDES
241DysuriaOFFSIDES
242EcthymaOFFSIDES
243Edema2998815CTD
244Electrocardiogram changeOFFSIDES
245Erosive gastritisOFFSIDES
246ErysipelasOFFSIDES
247EscharOFFSIDES
248Escherichia sepsisOFFSIDES
249Exanthema12445177CTD
250Exposure to toxic agentOFFSIDES
251Fatty LiverOFFSIDES
252Febrile NeutropeniaOFFSIDES
253Fever11852909CTD
254FibrosarcomaOFFSIDES
255Fistula dischargeOFFSIDES
256Gamma-Glutamyltransferase IncreasedOFFSIDES
257Gastrointestinal infectionOFFSIDES
258Genital dischargeOFFSIDES
259Genital erosionOFFSIDES
260GoiterOFFSIDES
261Granuloma12445177CTD
262HaematotoxicityOFFSIDES
263Hepatic artery stenosisOFFSIDES
264Hepatic congestionOFFSIDES
265Hepatic vein occlusionOFFSIDES
266Hepatitis B positiveOFFSIDES
267Hepatitis BOFFSIDES
268HepatitisOFFSIDES
269HidradenitisOFFSIDES
270Hyperalgesia2998815
8814464
9592021		CTD
271Hypertensive heart diseaseOFFSIDES
272HyperventilationOFFSIDES
273Immunosuppressant drug levelOFFSIDES
274Immunosuppressant drug level decreasedOFFSIDES
275Injection site inflammationOFFSIDES
276Intestinal anastomosis complicationOFFSIDES
277Kidney FailureOFFSIDES
278Leukopenia neonatalOFFSIDES
279Lip erosionOFFSIDES
280Liver Neoplasms, Experimental6150874
10077225		CTD
281MediastinitisOFFSIDES
282Mucosal erosionOFFSIDES
283Narcotic intoxicationOFFSIDES
284Nephrotic SyndromeOFFSIDES
285Neutropenic colitisOFFSIDES
286Open woundOFFSIDES
287OrthopneaOFFSIDES
288PROTHROMBIN TIMEOFFSIDES
289Pain of skinOFFSIDES
290Pain, Postoperative12577163CTD
291Panic DisorderOFFSIDES
292Performance status decreasedOFFSIDES
293Pericardial effusionOFFSIDES
294PericarditisOFFSIDES
295PolydactylyOFFSIDES
296Prenatal Exposure Delayed Effects8862987CTD
297Pseudomyxoma PeritoneiOFFSIDES
298Pulmonary congestionOFFSIDES
299PyelonephritisOFFSIDES
300Renal Colic10753031CTD
301Reticulocyte count decreasedOFFSIDES
302Ruptured cerebral aneurysmOFFSIDES
303Septic ShockOFFSIDES
304Soft tissue necrosisOFFSIDES
305Spinal Cord Diseases2378946CTD
306SpondylitisOFFSIDES
307SubileusOFFSIDES
308Substance Withdrawal Syndrome7954762CTD
309Synovial CystOFFSIDES
310SynovitisOFFSIDES
311TenosynovitisOFFSIDES
312ThyroiditisOFFSIDES
313Ultrasound scan abnormalOFFSIDES
314Vaginal abscessOFFSIDES
315Vascular encephalopathyOFFSIDES
316Visual disturbanceOFFSIDES
317Wound InfectionOFFSIDES
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