MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Thyrotoxicosis

(UMLS:C0040156)

Definition:: A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.
UMLS ID:: C0040156
MeSH ID:: D013971

Classification:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.874.397.685

Synonym(s)

Thyrotoxicosis

THYROTOXICOSIS

Thyrotoxicosis with or without goiter

Thyrotoxicosis, NOS

Thyrotoxicosis, unspecified

thyroid; toxic

thyrotoxicosis

toxic; thyroid

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Amiodarone	View details 3592436 6305250 7658748 11716246 12647553 16320682 16556715 16798157 18020914 18334037 18598099 19584973	CTD
2	Betaxolol		SIDER
3	Carbimazole	6548829 8542214 14530534	CTD
4	Celiprolol		SIDER
5	Dexamethasone	9392993	CTD
6	Ergotamine	16871899	CTD
7	Iodine	View details 7930488 8615390 15251663 19294866	CTD
8	Iohexol		SIDER
9	Labetalol		SIDER
10	Lithium Carbonate	8909171 15251733	CTD
11	Lithium		SIDER
12	Melatonin	18421916	CTD
13	Methimazole	View details 1657745 10999814 11745832 15251733	CTD
14	Methylprednisolone	8909171	CTD
15	Potassium Iodide	9392993	CTD
16	Propranolol	4392540 8542214	CTD
17	Propylthiouracil	View details 1110434 5659292 11745832 14530534	CTD
18	Sunitinib		SIDER
19	Thyroxine	9653867	CTD
20	Vitamin D	1657745	CTD
21	calcium lactate	1657745	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Euthyroid Sick Syndromes	31%
2	Goiter	31%
3	Hyperthyroxinemia	31%
4	Hypothyroidism	31%
5	Thyroiditis	31%
6	Secondary hypothyroidism	31%
7	Primary Hypothyroidism	31%
8	Graves Disease	27%
9	Thyroid Hormone Resistance Syndrome	20%
10	Adrenal Gland Diseases	18.5%
11	Gonadal Disorders	18.5%
12	Parathyroid Diseases	18.5%
13	Thyroid Neoplasm	16.4%
14	Thyroid carcinoma	16.4%
15	Hashimoto Disease	14.8%
16	Autoimmune thyroiditis	13.6%
17	Myxedema	13.3%
18	Bone Diseases, Endocrine	12.2%
19	Endocrine Gland Neoplasms	12.2%
20	Diabetes Mellitus	11.9%
21	Pituitary Diseases	11.8%
22	Thyroid Nodule	10.5%
23	Adrenal Cortex Diseases	10.3%
24	Adrenal Gland Neoplasms	10.3%
25	Hyperparathyroidism	10.3%
26	Hypogonadism	10.3%
27	Hypoparathyroidism	10.3%
28	Delayed Puberty	10.3%
29	Precocious Puberty	10.3%
30	Hypogonadotropic hypogonadism	10.3%
31	Testotoxicosis	10.3%
32	Congenital Hypothyroidism	10.1%
33	Dwarfism	8.9%
34	Parathyroid Neoplasms	8.2%
35	Testicular Diseases	7%
36	Ovarian Diseases	6.7%
37	Empty Sella Syndrome	6.7%
38	Hyperpituitarism	6.7%
39	Hypopituitarism	6.7%
40	Hypophysitis	6.7%
41	Cushing Syndrome	6.7%
42	Hyperaldosteronism	6.7%
43	Hyperparathyroidism, Secondary	6.7%
44	Hypoaldosteronism	6.7%
45	Hyperparathyroidism, Primary	6.7%
46	ovarian neoplasm	5.5%
47	Gestational Diabetes	5.1%
48	Latent Autoimmune Diabetes in Adults	5.1%
49	Diabetes Insipidus	5%
50	Diabetes Mellitus, Experimental	5%
51	Hyperglycemic Hyperosmolar Nonketotic Coma	4.9%
52	Adrenocortical carcinoma	4.8%
53	Testicular Neoplasms	4.8%
54	Addison Disease	4.5%
55	Diabetic Angiopathies	4.5%
56	Primary Adrenal Insufficiency	4.5%
57	Diabetic Neuropathies	4.4%
58	Orchitis	4.4%
59	Diabetic Amyotrophy	4.4%
60	Diabetic Autonomic Neuropathy	4.4%
61	Diabetic Cardiomyopathies	4.4%
62	Pituitary Adenoma	4.4%
63	Pituitary Neoplasms	4.4%
64	Ovarian Hyperstimulation Syndrome	4.4%
65	Hyperprolactinemia	4.4%
66	Prolactinoma	4.4%
67	Growth Hormone-Secreting Pituitary Adenoma	4.4%
68	Hermaphroditism	4.1%
69	Disorders of Sex Development	4.1%
70	Pituitary Apoplexy	3.9%
71	Diabetic Foot	3.9%
72	Nelson Syndrome	3.9%
73	Multiple Endocrine Neoplasia	3.4%
74	Pancreatic Neoplasm	3.4%
75	Corpus Luteum Cyst	3.3%
76	Ovarian Cysts	3.3%
77	Gigantism	3.3%
78	Diabetic Nephropathy	3.3%
79	Kallmann Syndrome	3.3%
80	Acromegaly	3.3%
81	Anovulation	3.3%
82	Diabetic Ketoacidosis	3.3%
83	Oophoritis	3.3%
84	granulosa cell tumor	3.2%
85	Carcinoma, Ovarian Epithelial	3.2%
86	Klinefelter Syndrome	2.8%
87	Cryptorchidism	2.7%
88	Gonadal Dysgenesis	2.6%
89	Adrenogenital Syndrome	2.6%
90	Ovotesticular Disorders of Sex Development	2.6%
91	Diabetic Retinopathy	2.5%
92	Polycystic Ovary Syndrome	2.4%
93	Leydig Cell Tumor	2.2%
94	Multiple Endocrine Neoplasia Type 1	2.2%
95	Hyperandrogenism	2.1%
96	Carcinoma, Pancreatic Ductal	1.6%
97	Turner Syndrome	1.4%
98	insulinoma	1.4%
99	Gastrinoma	1.4%
100	Glucagonoma	1.4%
101	Carcinoma, Endometrioid	1.4%
102	Waterhouse-Friderichsen Syndrome	1.3%
103	Renal Osteodystrophy	1.2%
104	Renal rickets	1.2%
105	Vipoma	1.2%
106	Adrenoleukodystrophy	0.8%
107	Denys-Drash Syndrome	0.7%

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