MetaADEDB 2.0 @ LMMD
Dronabinol
(CYQFCXCEBYINGO-IAGOWNOFSA-N)
Structure
SMILES
CCCCCc1cc(O)c2c(c1)OC([C@H]1[C@H]2C=C(C)CC1)(C)C
Type(s)
Approved; Illicit
ATC code(s)
A04AD10
Molecular Formula:
C21H30O2
Molecular Weight:
314.462
Log P:
5.7358
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
1
TPSA:
29.46
CAS Number(s):
1972-08-3; 6465-30-1; 26514
Synonym(s)
1.
Dronabinol
2.
THC
3.
Tetrahydrocannabinol
4.
delta(9)-THC
5.
9-ene-Tetrahydrocannabinol
6.
Marinol
7.
Tetrahydrocannabinol, (6a-trans)-Isomer
8.
Tetrahydrocannabinol, (6aR-cis)-Isomer
9.
Tetrahydrocannabinol, (6aS-cis)-Isomer
10.
Tetrahydrocannabinol, Trans-(+-)-Isomer
11.
Tetrahydrocannabinol, Trans-Isomer
12.
delta(1)-THC
13.
delta(1)-Tetrahydrocannabinol
14.
delta(9)-Tetrahydrocannabinol
15.
9 ene Tetrahydrocannabinol
16.
Tetrahydrocannabinol, Trans Isomer
External Link(s)
MeSHD013759
PubChem Compound16078
BindingDB50007391
60994
ChEBI66964
CHEMBLCHEMBL465
DrugBankDB00470
DrugCentral4109
IUPHAR/BPS Guide to PHARMACOLOGY2424
KEGGcpd:C06972
dr:D00306
Therapeutic Target DatabaseD0L4AI
D0P1FO
ZINC1530625
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 31US FAERS
2NauseaFAERS: 29
Canada Vigilance: 1		15323605CTD
OFFSIDES
Canada Vigilance
US FAERS
3VomitingFAERS: 22
Canada Vigilance: 2		7689702CTD
Canada Vigilance
US FAERS
4MalaiseFAERS: 15US FAERS
5Weight decreasedFAERS: 13US FAERS
6PainFAERS: 11

View details

11168564
11359533
12467995
19041390
 		CTD
OFFSIDES
US FAERS
7DizzinessFAERS: 10OFFSIDES
US FAERS
8Feeling abnormalFAERS: 9US FAERS
9Drug screen positiveFAERS: 8US FAERS
10Incorrect product storageFAERS: 8US FAERS
11SomnolenceFAERS: 8US FAERS
12Abdominal PainFAERS: 7
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
13Therapeutic response unexpectedFAERS: 7US FAERS
14AnxietyFAERS: 5OFFSIDES
US FAERS
15DehydrationFAERS: 5OFFSIDES
US FAERS
16Drug dose omissionFAERS: 5US FAERS
17Euphoric moodFAERS: 5US FAERS
18HeadacheFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
19ParanoiaFAERS: 5US FAERS
20Product taste abnormalFAERS: 5US FAERS
21Abdominal discomfortFAERS: 4OFFSIDES
US FAERS
22AstheniaFAERS: 4OFFSIDES
US FAERS
23Chest PainFAERS: 4OFFSIDES
US FAERS
24Myocardial InfarctionFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
25Post procedural complicationFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
26Product quality issueFAERS: 4US FAERS
27Product storage errorFAERS: 4US FAERS
28TremorFAERS: 4US FAERS
29Unevaluable eventFAERS: 4US FAERS
30Adverse eventFAERS: 3US FAERS
31ConstipationFAERS: 3US FAERS
32FatigueFAERS: 3OFFSIDES
US FAERS
33PancreatitisFAERS: 3US FAERS
34Product physical issueFAERS: 3US FAERS
35Throat irritationFAERS: 3US FAERS
36ThrombosisFAERS: 3US FAERS
37Wrong technique in drug usage processFAERS: 3US FAERS
38Wrong technique in product usage processFAERS: 3US FAERS
39AbasiaFAERS: 2US FAERS
40Activities of daily living impairedFAERS: 2OFFSIDES
US FAERS
41AngerFAERS: 2US FAERS
42AphasiaFAERS: 2US FAERS
43DisabilityFAERS: 2US FAERS
44Drug ineffective for unapproved indicationFAERS: 2US FAERS
45Drug prescribing errorFAERS: 2OFFSIDES
US FAERS
46DysarthriaFAERS: 2US FAERS
47DysgeusiaFAERS: 2OFFSIDES
US FAERS
48Electrolyte imbalanceFAERS: 2US FAERS
49Epinephrine increasedFAERS: 2US FAERS
50Exposure via skin contactFAERS: 2US FAERS
51FlatulenceFAERS: 2US FAERS
52HypophagiaFAERS: 2US FAERS
53Incorrect route of drug administrationFAERS: 2US FAERS
54Incorrect storage of drugFAERS: 2US FAERS
55InfectionFAERS: 2OFFSIDES
US FAERS
56Medication ErrorFAERS: 2US FAERS
57Medication residue presentFAERS: 2US FAERS
58Mental status changesFAERS: 2OFFSIDES
US FAERS
59PneumoniaFAERS: 2US FAERS
60Poor quality drug administeredFAERS: 2US FAERS
61Post-Traumatic Stress DisorderFAERS: 2US FAERS
62Prescribed overdoseFAERS: 2US FAERS
63Urine cannabinoids increasedFAERS: 2US FAERS
64nervous system disorderFAERS: 2US FAERS
65Accidental exposureFAERS: 1US FAERS
66AgitationFAERS: 1US FAERS
67AmnesiaFAERS: 1US FAERS
68Back PainFAERS: 1US FAERS
69Back disorderFAERS: 1US FAERS
70Blood glucose decreasedFAERS: 1US FAERS
71Blood glucose normalFAERS: 1US FAERS
72BronchitisFAERS: 1US FAERS
73Capsule issueFAERS: 1US FAERS
74Capsule physical issueFAERS: 1US FAERS
75Central pain syndromeFAERS: 1US FAERS
76Chest discomfortFAERS: 1US FAERS
77ChoreoathetosisFAERS: 1US FAERS
78Cogwheel RigidityFAERS: 1US FAERS
79Diabetes MellitusFAERS: 1US FAERS
80Diabetic KetoacidosisFAERS: 1US FAERS
81DisorientationFAERS: 1US FAERS
82Drug DependenceFAERS: 1US FAERS
83Drug administration errorFAERS: 1US FAERS
84Drug dispensing errorFAERS: 1US FAERS
85Drug effect delayedFAERS: 1US FAERS
86Drug effect incompleteFAERS: 1US FAERS
87Drug level increasedFAERS: 1US FAERS
88DyspepsiaFAERS: 1US FAERS
89DysuriaFAERS: 1OFFSIDES
US FAERS
90Enamel anomalyFAERS: 1US FAERS
91EructationFAERS: 1US FAERS
92FibromyalgiaFAERS: 1US FAERS
93Foaming at mouthFAERS: 1US FAERS
94Food AllergyFAERS: 1US FAERS
95GastroenteritisFAERS: 1OFFSIDES
US FAERS
96Gastrointestinal motility disorderFAERS: 1US FAERS
97Hepatic cancer stage IVFAERS: 1US FAERS
98Hospice CareFAERS: 1US FAERS
99HyperchlorhydriaFAERS: 1US FAERS
100HypotensionFAERS: 16257883
9190833		CTD
US FAERS
101Inappropriate schedule of drug administrationFAERS: 1OFFSIDES
US FAERS
102Incorrect route of product administrationFAERS: 1US FAERS
103Intervertebral Disc DegenerationFAERS: 1OFFSIDES
US FAERS
104LethargyFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
105LeukocytosisFAERS: 1US FAERS
106Limb discomfortFAERS: 1US FAERS
107Lip swellingFAERS: 1US FAERS
108Loss of personal independence in daily activitiesFAERS: 1US FAERS
109MalabsorptionFAERS: 1US FAERS
110MalnutritionFAERS: 1US FAERS
111Medication residueFAERS: 1US FAERS
112Mouth swellingFAERS: 1US FAERS
113Multiple SclerosisFAERS: 1US FAERS
114Muscle RigidityFAERS: 1US FAERS
115MyoclonusFAERS: 1US FAERS
116Occupational exposure to productFAERS: 1US FAERS
117Oropharyngeal painFAERS: 1US FAERS
118Osteogenesis ImperfectaFAERS: 1US FAERS
119OverdoseFAERS: 1US FAERS
120PalpitationsFAERS: 1US FAERS
121Patella replacementFAERS: 1US FAERS
122Pelvic massFAERS: 1US FAERS
123Peripheral swellingFAERS: 1US FAERS
124Pharmaceutical product complaintFAERS: 1US FAERS
125Post procedural infectionFAERS: 1US FAERS
126Pre-existing condition improvedFAERS: 1US FAERS
127Product shape issueFAERS: 1US FAERS
128Product substitution issueFAERS: 1US FAERS
129PruritusFAERS: 1US FAERS
130Pulmonary EmbolismFAERS: 1US FAERS
131Pulmonary FibrosisFAERS: 1US FAERS
132Respiratory arrestFAERS: 1US FAERS
133RetchingFAERS: 1US FAERS
134SepsisFAERS: 1US FAERS
135Superior Mesenteric Artery SyndromeFAERS: 1US FAERS
136SyncopeFAERS: 1US FAERS
137Therapeutic product effect delayedFAERS: 1US FAERS
138Therapeutic product effect incompleteFAERS: 1US FAERS
139Therapeutic response changedFAERS: 1US FAERS
140Tongue discomfortFAERS: 1US FAERS
141UrticariaFAERS: 1US FAERS
142VertigoFAERS: 1US FAERS
143Wrong patient received medicationFAERS: 1US FAERS
144Abdominal AbscessOFFSIDES
145Abnormal visionOFFSIDES
146Abnormalities, Drug-Induced29106691CTD
147Acid refluxOFFSIDES
148AcidosisOFFSIDES
149AcneOFFSIDES
150Activated partial thromboplastin time abnormalOFFSIDES
151Acute kidney injury16161930CTD
152Acute sinusitisOFFSIDES
153AgeusiaOFFSIDES
154AgraphiaOFFSIDES
155AkathisiaCanada Vigilance: 1Canada Vigilance
156Alanine Aminotransferase IncreasedOFFSIDES
157Alanine aminotransferase abnormalOFFSIDES
158AlveolitisOFFSIDES
159Amyotrophic Lateral Sclerosis15204022CTD
160AneurysmOFFSIDES
161AnhedoniaOFFSIDES
162AnhidrosisOFFSIDES
163AnorexiaOFFSIDES
164Anxiety Disorders8788864CTD
165Aortic AneurysmOFFSIDES
166ApneaOFFSIDES
167ArteriosclerosisOFFSIDES
168ArthritisOFFSIDES
169AscitesOFFSIDES
170Aseptic MeningitisOFFSIDES
171AtelectasisOFFSIDES
172Atherosclerosis15815632CTD
173Atrial tachycardiaOFFSIDES
174AuraOFFSIDES
175Bacterial test positiveOFFSIDES
176Biliary DyskinesiaOFFSIDES
177Biliary adenomaOFFSIDES
178Bilirubin conjugated increasedOFFSIDES
179Bipolar Disorder6295192CTD
180Bladder calculus removalOFFSIDES
181BlepharospasmOFFSIDES
182Blood calcium abnormalOFFSIDES
183Blood chloride abnormalOFFSIDES
184Blood creatinine increasedOFFSIDES
185Blood fibrinogen abnormalOFFSIDES
186Blood pH increasedOFFSIDES
187Blood potassium decreasedOFFSIDES
188Blood potassium increasedOFFSIDES
189Blood potassiumOFFSIDES
190Blood pressure fluctuationOFFSIDES
191Blood sodium abnormalOFFSIDES
192Blood sodium increasedOFFSIDES
193Blood sodiumOFFSIDES
194Blood testosterone decreasedOFFSIDES
195Blood urea abnormalOFFSIDES
196Blood urea increasedOFFSIDES
197Blood urine presentOFFSIDES
198Bone density decreasedOFFSIDES
199Bone fistulaOFFSIDES
200Bone fragmentationOFFSIDES
201Bone lesionOFFSIDES
202Bone painOFFSIDES
203Bone trimmingOFFSIDES
204Bradycardia652837
885163
9190833		CTD
205Brain Edema11517236
19782326		CTD
206Breast cancer recurrentOFFSIDES
207Breast tendernessOFFSIDES
208Carnitine deficiencyOFFSIDES
209Catalepsy

View details

2530142
3031535
8788864
10318961
11080195
12970091
18789920
19041390
 		CTD
210Cataract operationOFFSIDES
211Catheter placementOFFSIDES
212Catheter related complicationOFFSIDES
213Catheter related infectionOFFSIDES
214Catheter site cellulitisOFFSIDES
215Catheter site infectionOFFSIDES
216CellulitisOFFSIDES
217Cerebral ArteriosclerosisOFFSIDES
218Cerebral Infarction17289082CTD
219CheilitisOFFSIDES
220Choking sensationOFFSIDES
221ChromaturiaOFFSIDES
222Chronic Obstructive Airway DiseaseOFFSIDES
223Clostridium colitisOFFSIDES
224Clostridium difficile colitisOFFSIDES
225Cognition Disorders16510488
17578508
24776491		CTD
226ColitisOFFSIDES
227Concomitant disease progressionOFFSIDES
228ConfabulationOFFSIDES
229Congenital cystic kidney diseaseOFFSIDES
230Culture positiveOFFSIDES
231CystOFFSIDES
232Deafness NeurosensoryOFFSIDES
233DeafnessOFFSIDES
234DebridementOFFSIDES
235DemyelinationOFFSIDES
236Dental FistulaOFFSIDES
237Dental abscessOFFSIDES
238Dental cariesOFFSIDES
239Dental discomfortOFFSIDES
240Device leakageOFFSIDES
241Device occlusionOFFSIDES
242Device related infectionOFFSIDES
243Diabetes Mellitus, Experimental11357882CTD
244DiarrheaOFFSIDES
245Diffuse Large B-Cell LymphomaOFFSIDES
246Diffuse alveolar damageOFFSIDES
247DiplopiaOFFSIDES
248Disease ProgressionOFFSIDES
249Disseminated Intravascular Coagulation16161930CTD
OFFSIDES
250DiverticulumOFFSIDES
251Drug withdrawal headacheOFFSIDES
252Dry skinOFFSIDES
253Duodenal ulcer perforationOFFSIDES
254DysphemiaOFFSIDES
255DystoniaCanada Vigilance: 1Canada Vigilance
256Ecchymosis16161930CTD
257Ejection Fraction DecreasedOFFSIDES
258Electromechanical dissociationOFFSIDES
259Emotional disorderOFFSIDES
260Endodontic procedureOFFSIDES
261EnteritisOFFSIDES
262Enterococcal infectionOFFSIDES
263EpicondylitisOFFSIDES
264Epidural AbscessOFFSIDES
265Epilepsy821787CTD
266EpistaxisOFFSIDES
267Erosive gastritisOFFSIDES
268ErythemaOFFSIDES
269Eustachian tube disorderOFFSIDES
270ExcoriationOFFSIDES
271Exfoliative rashOFFSIDES
272Failure to ThriveOFFSIDES
273Fat necrosisOFFSIDES
274Febrile NeutropeniaOFFSIDES
275FormicationOFFSIDES
276GammopathyOFFSIDES
277General physical health deteriorationOFFSIDES
278Glioma10700234CTD
279GranulocytosisOFFSIDES
280Hearing aid userOFFSIDES
281HiccoughOFFSIDES
282Huntington Disease20929960CTD
283HydronephrosisOFFSIDES
284HyperpigmentationOFFSIDES
285Hypovolemia16161930CTD
286HypoxiaOFFSIDES
287Immune reconstitution syndromeOFFSIDES
288Implant site dischargeOFFSIDES
289Infected cystOFFSIDES
290Inflammation7689702CTD
291Infusion site mobility decreasedOFFSIDES
292Intermittent ClaudicationOFFSIDES
293Intervertebral disc disorderOFFSIDES
294Kidney FailureOFFSIDES
295Leukopenia neonatalOFFSIDES
296Leukopenia30130528CTD
297Life expectancy shortenedOFFSIDES
298Liver transplant rejectionOFFSIDES
299Loose toothOFFSIDES
300LymphedemaOFFSIDES
301MacroglossiaOFFSIDES
302Malignant neoplasm progressionOFFSIDES
303Malignant tumour excisionOFFSIDES
304Mallory-Weiss SyndromeOFFSIDES
305Marijuana Abuse18563365CTD
306Mass excisionOFFSIDES
307Mastication disorderOFFSIDES
308Medical device complicationOFFSIDES
309Medical device removalOFFSIDES
310Memory Disorders

View details

16406104
16510488
16936704
21767554
 		CTD
311Metastases to adrenalsOFFSIDES
312Metastatic NeoplasmOFFSIDES
313Metastatic Renal Cell CarcinomaOFFSIDES
314Monoclonal immunoglobulin presentOFFSIDES
315Morphine Dependence9734704
10727732		CTD
316Motion SicknessOFFSIDES
317Movement Disorders

View details

9748483
10802025
15882845
16137723
20929960
22226049
 		CTD
318Mucosal erosionOFFSIDES
319Multiple MyelomaOFFSIDES
320Multiple drug overdoseOFFSIDES
321Multiple sclerosis relapseOFFSIDES
322Muscle WeaknessOFFSIDES
323Musculoskeletal chest painOFFSIDES
324Mycobacterium avium complex immune restoration diseaseOFFSIDES
325Nasal mucosal disorderOFFSIDES
326Nephrogenic Fibrosing DermopathyOFFSIDES
327NephrolithiasisOFFSIDES
328Nerve BlockOFFSIDES
329Nerve Degeneration11517236
15640759		CTD
330Neural Tube Defects19040278CTD
331Neutrophil count abnormalOFFSIDES
332NocturiaOFFSIDES
333NoduleOFFSIDES
334ObstructionOFFSIDES
335Open woundOFFSIDES
336Opioid-Related Disorders16823391CTD
337Oral infectionOFFSIDES
338OsteomyelitisOFFSIDES
339OsteoporosisOFFSIDES
340PallorOFFSIDES
341Peptostreptococcus infectionOFFSIDES
342PericarditisOFFSIDES
343PeriodontitisOFFSIDES
344Personality Disorders6324245CTD
345Pleural InfectionOFFSIDES
346PneumothoraxOFFSIDES
347Poisoning23494106CTD
348PolyuriaOFFSIDES
349Portal Vein ThrombosisOFFSIDES
350Pregnancy Complications16886060CTD
351Prenatal Exposure Delayed Effects

View details

7776847
8968950
9188039
9734704
10727732
12456917
17578508
21820648
30594692
 		CTD
352Primary sequestrumOFFSIDES
353Productive CoughOFFSIDES
354Prostate examination abnormalOFFSIDES
355Prosthesis ImplantationOFFSIDES
356Prothrombin time abnormalOFFSIDES
357Psychoses, Substance-Induced16612464CTD
358Pulmonary Edema19782326CTD
359Pulmonary radiation injuryOFFSIDES
360Purpura16161930CTD
361PurulenceOFFSIDES
362Quadriplegia16161930CTD
363Residual urineOFFSIDES
364Respiratory FailureOFFSIDES
365Respiratory tract congestionOFFSIDES
366Respiratory tract infection fungalOFFSIDES
367Rhabdomyolysis16161930CTD
368RhinitisOFFSIDES
369RhonchiOFFSIDES
370Saliva alteredOFFSIDES
371Seizures

View details

841172
982057
6268703
6299864
7689702
12954810
22079489
 		CTD
372SequestrectomyOFFSIDES
373SeromaOFFSIDES
374Skin ErosionOFFSIDES
375Skin neoplasm excisionOFFSIDES
376Stem cell transplantOFFSIDES
377Stereotypic Movement Disorder9988095CTD
378StressOFFSIDES
379Substance Withdrawal Syndrome

View details

988178
2560590
10727732
11359533
 		CTD
380Substance-Related Disorders21300050CTD
381Sudden deathOFFSIDES
382Tachycardia885163
6257883		CTD
383Teeth brittleOFFSIDES
384Tongue bitingOFFSIDES
385Tooth ErosionOFFSIDES
386Tooth ExtractionOFFSIDES
387Tooth InfectionOFFSIDES
388Tooth ResorptionOFFSIDES
389Urinary tract infection enterococcalOFFSIDES
390Veillonella infectionOFFSIDES
391Venous occlusionOFFSIDES
392Visual disturbanceOFFSIDES
393Vitreous DetachmentOFFSIDES
394Wound ComplicationOFFSIDES
395Wound dehiscenceOFFSIDES
396Wound infection staphylococcalOFFSIDES
397colonoscopyOFFSIDES
398kyphosisOFFSIDES
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