Nalidixic Acid
(MHWLWQUZZRMNGJ-UHFFFAOYSA-N)
Structure
- SMILES
- CCn1cc(C(=O)O)c(=O)c2c1nc(C)cc2
- Type(s)
- Approved; Investigational
- ATC code(s)
- J01MB02
- Molecular Formula:
- C12H12N2O3
- Molecular Weight:
- 232.235
- Log P:
- 1.4230
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 1
- TPSA:
- 72.19
- CAS Number(s):
- 389-08-2
Synonym(s)
1.
Nalidixic Acid
2.
Nalidixin
3.
Nalidixate Sodium
4.
Nalidixate Sodium Anhydrous
5.
Nevigramon
6.
Sodium Nalidixic Acid, Anhydrous
7.
Sodium Nalidixic Acid, Monohydrate
8.
Acid, Nalidixic
9.
Anhydrous, Nalidixate Sodium
10.
Sodium Anhydrous, Nalidixate
11.
Sodium, Nalidixate
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 3 | US FAERS | |
| 2 | Pain | FAERS: 3 Canada Vigilance: 1 | 3147757 | CTD Canada Vigilance US FAERS |
| 3 | Agitation | FAERS: 2 | US FAERS | |
| 4 | Dependence | FAERS: 2 | US FAERS | |
| 5 | Product quality issue | FAERS: 2 | US FAERS | |
| 6 | Somnolence | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance SIDER US FAERS | |
| 7 | Accidental overdose | FAERS: 1 | US FAERS | |
| 8 | Bradycardia | FAERS: 1 | US FAERS | |
| 9 | Chills | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 10 | Cold sweat | FAERS: 1 | US FAERS | |
| 11 | Feeling Cold | FAERS: 1 | US FAERS | |
| 12 | Mydriasis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | Staring | FAERS: 1 | US FAERS | |
| 14 | Abdominal Pain | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 15 | Abdominal discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 16 | Abducens Nerve Diseases | 5313954 | CTD | |
| 17 | Acid-Base Imbalance | 847456 | CTD | |
| 18 | Acidosis | 17175866 | CTD | |
| 19 | Anaphylactic shock | SIDER | ||
| 20 | Anaphylactoid Reaction | SIDER | ||
| 21 | Anemia, Hemolytic | 1597360 4190560 | CTD | |
| 22 | Angioedema | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 23 | Anxiety | Canada Vigilance: 1 | Canada Vigilance | |
| 24 | Arthralgia | Canada Vigilance: 3 | Canada Vigilance SIDER | |
| 25 | Arthritis | Canada Vigilance: 2 | Canada Vigilance | |
| 26 | Arthropathy | Canada Vigilance: 1 | Canada Vigilance | |
| 27 | Asthenia | Canada Vigilance: 4 | Canada Vigilance SIDER | |
| 28 | Ataxia | Canada Vigilance: 1 | Canada Vigilance | |
| 29 | Back Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 30 | Bronchospasm | Canada Vigilance: 2 | Canada Vigilance | |
| 31 | Cerebellar Hypoplasia | Canada Vigilance: 1 | Canada Vigilance | |
| 32 | Cerebral Arteriosclerosis | SIDER | ||
| 33 | Chemical and Drug Induced Liver Injury | 4143406 | CTD | |
| 34 | Cholestasis | 4143406 | CTD SIDER | |
| 35 | Chromatopsia | Canada Vigilance: 2 | Canada Vigilance | |
| 36 | Cochlear Diseases | 1622440 | CTD | |
| 37 | Confusion | 7360651 | CTD | |
| 38 | Conjunctivitis | Canada Vigilance: 1 | Canada Vigilance | |
| 39 | Cyanosis | Canada Vigilance: 1 | Canada Vigilance | |
| 40 | Depressed Level of Consciousness | Canada Vigilance: 1 | Canada Vigilance | |
| 41 | Dermatitis | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 42 | Diplopia | SIDER | ||
| 43 | Disorientation | Canada Vigilance: 3 | Canada Vigilance | |
| 44 | Dizziness | Canada Vigilance: 8 | Canada Vigilance SIDER | |
| 45 | Drowsiness | SIDER | ||
| 46 | Drug Overdose | 553453 1972527 17175866 | CTD | |
| 47 | Dysentery, Bacillary | 1972527 | CTD | |
| 48 | Dysentery | 10063299 | CTD | |
| 49 | Dyspepsia | Canada Vigilance: 1 | Canada Vigilance | |
| 50 | Eosinophilia | SIDER | ||
| 51 | Epilepsy | SIDER | ||
| 52 | Erythema Multiforme | SIDER | ||
| 53 | Erythema | Canada Vigilance: 4 | Canada Vigilance SIDER | |
| 54 | Flushing | Canada Vigilance: 2 | Canada Vigilance | |
| 55 | Gastrointestinal Pain | SIDER | ||
| 56 | Hallucinations | 7360651 | CTD | |
| 57 | Headache | Canada Vigilance: 5 | Canada Vigilance SIDER | |
| 58 | Hyperglycemia | 589309 1445173 | CTD | |
| 59 | Hyperkinesia | Canada Vigilance: 1 | Canada Vigilance | |
| 60 | Hypersensitivity | Canada Vigilance: 2 | Canada Vigilance | |
| 61 | Hypotension | Canada Vigilance: 1 | Canada Vigilance | |
| 62 | Intracranial Hypertension | CTD | ||
| 63 | Joint stiffness | SIDER | ||
| 64 | Kidney Diseases | 1136371 | CTD | |
| 65 | Leukopenia | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 66 | Malaise | Canada Vigilance: 1 | Canada Vigilance | |
| 67 | Metabolic acidosis | SIDER | ||
| 68 | Musculoskeletal discomfort | SIDER | ||
| 69 | Myalgia | Canada Vigilance: 1 | Canada Vigilance | |
| 70 | Nausea | Canada Vigilance: 6 | Canada Vigilance SIDER | |
| 71 | Optic Neuritis | SIDER | ||
| 72 | Pallor | Canada Vigilance: 1 | Canada Vigilance | |
| 73 | Palpitations | Canada Vigilance: 3 | Canada Vigilance | |
| 74 | Papilledema | 4583929 5313954 6025983 | CTD | |
| 75 | Petechiae | Canada Vigilance: 2 | Canada Vigilance | |
| 76 | Pharyngitis | Canada Vigilance: 2 | Canada Vigilance | |
| 77 | Photophobia | Canada Vigilance: 5 | Canada Vigilance | |
| 78 | Polyarthritis | Canada Vigilance: 1 | Canada Vigilance | |
| 79 | Pruritus | Canada Vigilance: 8 | Canada Vigilance SIDER | |
| 80 | Pseudotumor Cerebri | 1972527 4604984 10063299 | CTD | |
| 81 | Psychoses, Substance-Induced | 17175866 | CTD | |
| 82 | Purpura | Canada Vigilance: 3 | Canada Vigilance | |
| 83 | Rash erythematous | Canada Vigilance: 3 | Canada Vigilance | |
| 84 | Respiration Disorders | 17175866 | CTD | |
| 85 | Restlessness | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Retinal Detachment | Canada Vigilance: 1 | Canada Vigilance | |
| 87 | Seizures | CTD | ||
| 88 | Sense of oppression | Canada Vigilance: 1 | Canada Vigilance | |
| 89 | Serum Sickness | Canada Vigilance: 1 | Canada Vigilance | |
| 90 | Stevens-Johnson Syndrome | SIDER | ||
| 91 | Strabismus | 5313954 | CTD | |
| 92 | Swelling | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 93 | Syncope | Canada Vigilance: 1 | Canada Vigilance | |
| 94 | Tachycardia | Canada Vigilance: 4 | Canada Vigilance | |
| 95 | Thrombocytopenia | SIDER | ||
| 96 | Thrombocytopenic purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 97 | Trauma | SIDER | ||
| 98 | Tremor | Canada Vigilance: 2 | Canada Vigilance | |
| 99 | Urologic Diseases | 1136371 | CTD | |
| 100 | Urticaria | Canada Vigilance: 13 | Canada Vigilance SIDER | |
| 101 | Vertigo | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 102 | Visual Impairment | Canada Vigilance: 3 | Canada Vigilance SIDER | |
| 103 | Vomiting | Canada Vigilance: 3 | CTD SIDER Canada Vigilance | |
| 104 | jaundice | 4653901 | CTD |
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