candesartan cilexetil
(GHOSNRCGJFBJIB-UHFFFAOYSA-N)
Structure
- SMILES
- CCOc1nc2c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)c(ccc2)C(=O)OC(OC(=O)OC1CCCCC1)C
- Type(s)
- Approved
- Molecular Formula:
- C33H34N6O6
- Molecular Weight:
- 610.660
- Log P:
- 6.3191
- Hydrogen Bond Acceptor:
- 11
- Hydrogen Bond Donor:
- 1
- TPSA:
- 143.34
- CAS Number(s):
- 145040-37-5
Synonym(s)
1.
candesartan cilexetil
2.
1-(cyclohexylocarbonyloxy)ethyl-2-ethoxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)-1H-benzimidazole-7-carboxylate
3.
Amias
4.
Atacand
5.
Blopress
6.
Kenzen
7.
Parapres
8.
TCV 116
9.
TCV-116
External Link(s)
| MeSH | C077793 |
| PubChem Compound | 2540 |
| BindingDB | 50318907 |
| ChEBI | 3348 |
| CHEMBL | CHEMBL1014 |
| DrugBank | DB00796 |
| DrugCentral | 475 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 8352 |
| KEGG | cpd:C07709 dr:D00626 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 112 Canada Vigilance: 52 | Canada Vigilance US FAERS | |
| 2 | Malaise | FAERS: 77 Canada Vigilance: 8 | Canada Vigilance US FAERS | |
| 3 | Drug dose omission | FAERS: 74 | US FAERS | |
| 4 | Cerebrovascular accident | FAERS: 55 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 5 | Dizziness | FAERS: 54 Canada Vigilance: 23 | Canada Vigilance OFFSIDES US FAERS | |
| 6 | Headache | FAERS: 39 Canada Vigilance: 25 | Canada Vigilance US FAERS | |
| 7 | Fatigue | FAERS: 34 Canada Vigilance: 10 | Canada Vigilance OFFSIDES US FAERS | |
| 8 | Hypotension | FAERS: 27 | US FAERS | |
| 9 | Diabetes Mellitus | FAERS: 25 | US FAERS | |
| 10 | Blood pressure inadequately controlled | FAERS: 22 Canada Vigilance: 19 | Canada Vigilance OFFSIDES US FAERS | |
| 11 | Adverse event | FAERS: 20 | US FAERS | |
| 12 | Drug exposure during pregnancy | FAERS: 20 | US FAERS | |
| 13 | Nausea | FAERS: 19 Canada Vigilance: 30 | Canada Vigilance US FAERS | |
| 14 | Back Pain | FAERS: 18 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 15 | Weight decreased | FAERS: 18 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 16 | Chest Pain | FAERS: 17 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 17 | Oligohydramnios | FAERS: 17 | OFFSIDES US FAERS | |
| 18 | Asthenia | FAERS: 16 Canada Vigilance: 8 | Canada Vigilance OFFSIDES US FAERS | |
| 19 | Feeling abnormal | FAERS: 16 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 20 | Arthralgia | FAERS: 15 | US FAERS | |
| 21 | Myocardial Infarction | FAERS: 15 | US FAERS | |
| 22 | Pruritus | FAERS: 15 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 23 | Blood pressure fluctuation | FAERS: 14 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 24 | Memory impairment | FAERS: 14 | US FAERS | |
| 25 | Myalgia | FAERS: 14 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 26 | Angioedema | FAERS: 13 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 27 | Pain | FAERS: 13 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 28 | Intentional drug misuse | FAERS: 12 | US FAERS | |
| 29 | Stress | FAERS: 12 | US FAERS | |
| 30 | Abdominal Pain | FAERS: 11 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 31 | Anxiety | FAERS: 11 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 32 | Pneumonia | FAERS: 11 | US FAERS | |
| 33 | Alopecia | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 34 | Amnesia | FAERS: 10 | US FAERS | |
| 35 | Blood creatinine increased | FAERS: 10 Canada Vigilance: 3 | Canada Vigilance OFFSIDES US FAERS | |
| 36 | Joint swelling | FAERS: 10 | US FAERS | |
| 37 | Nasopharyngitis | FAERS: 10 | US FAERS | |
| 38 | Syncope | FAERS: 10 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 39 | Visual Impairment | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 40 | Bradycardia | FAERS: 9 | OFFSIDES US FAERS | |
| 41 | Dyspepsia | FAERS: 9 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 42 | Infarction | FAERS: 9 | US FAERS | |
| 43 | Palpitations | FAERS: 9 Canada Vigilance: 10 | Canada Vigilance US FAERS | |
| 44 | Vomiting | FAERS: 9 Canada Vigilance: 12 | Canada Vigilance US FAERS | |
| 45 | Wrong technique in drug usage process | FAERS: 9 | US FAERS | |
| 46 | Asthma | FAERS: 8 | OFFSIDES US FAERS | |
| 47 | Cardiac Arrest | FAERS: 8 | US FAERS | |
| 48 | Chest discomfort | FAERS: 8 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 49 | Gout | FAERS: 8 | US FAERS | |
| 50 | Joint injury | FAERS: 8 | US FAERS | |
| 51 | Maternal exposure during pregnancy | FAERS: 8 | US FAERS | |
| 52 | Nervousness | FAERS: 8 | US FAERS | |
| 53 | Sinusitis | FAERS: 8 | OFFSIDES US FAERS | |
| 54 | Suicide attempt | FAERS: 8 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 55 | Arthritis | FAERS: 7 | US FAERS | |
| 56 | Cholestasis | FAERS: 7 | US FAERS | |
| 57 | Incorrect dose administered | FAERS: 7 | US FAERS | |
| 58 | Vertigo | FAERS: 7 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 59 | Blood cholesterol increased | FAERS: 6 | US FAERS | |
| 60 | Erectile dysfunction | FAERS: 6 | US FAERS | |
| 61 | Glaucoma | FAERS: 6 | US FAERS | |
| 62 | Overdose | FAERS: 6 | US FAERS | |
| 63 | Therapeutic response unexpected | FAERS: 6 | US FAERS | |
| 64 | Abdominal discomfort | FAERS: 5 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 65 | Acute kidney injury | FAERS: 5 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 66 | Agitation | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 67 | Aphagia | FAERS: 5 | US FAERS | |
| 68 | Blood creatine phosphokinase increased | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 69 | Cataract | FAERS: 5 | OFFSIDES US FAERS | |
| 70 | Constipation | FAERS: 5 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 71 | Cytolytic hepatitis | FAERS: 5 | OFFSIDES US FAERS | |
| 72 | Erythema | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 73 | Hepatitis | FAERS: 5 | OFFSIDES US FAERS | |
| 74 | Hypertensive crisis | FAERS: 5 | US FAERS | |
| 75 | Influenza | FAERS: 5 | US FAERS | |
| 76 | Medication Error | FAERS: 5 | US FAERS | |
| 77 | Oropharyngeal pain | FAERS: 5 | US FAERS | |
| 78 | Pancreatitis | FAERS: 5 | US FAERS | |
| 79 | Pregnancy | FAERS: 5 | US FAERS | |
| 80 | Respiratory Failure | FAERS: 5 | OFFSIDES US FAERS | |
| 81 | Somnolence | FAERS: 5 | US FAERS | |
| 82 | Tinnitus | FAERS: 5 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 83 | Urinary tract infection | FAERS: 5 | US FAERS | |
| 84 | Anal Fissure | FAERS: 4 | US FAERS | |
| 85 | Aphasia | FAERS: 4 | US FAERS | |
| 86 | Blood cholesterol abnormal | FAERS: 4 | US FAERS | |
| 87 | Cardiomegaly | FAERS: 4 | 10779124 11518847 | CTD US FAERS |
| 88 | Cerebral Infarction | FAERS: 4 | US FAERS | |
| 89 | Chills | FAERS: 4 | US FAERS | |
| 90 | Disability | FAERS: 4 | US FAERS | |
| 91 | Drug prescribing error | FAERS: 4 | US FAERS | |
| 92 | Dysarthria | FAERS: 4 | US FAERS | |
| 93 | Dysgeusia | FAERS: 4 | US FAERS | |
| 94 | Dysphonia | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 95 | Dysuria | FAERS: 4 | US FAERS | |
| 96 | Flatulence | FAERS: 4 | US FAERS | |
| 97 | General physical health deterioration | FAERS: 4 | OFFSIDES US FAERS | |
| 98 | Hepatomegaly | FAERS: 4 | US FAERS | |
| 99 | Hypomania | FAERS: 4 | OFFSIDES US FAERS | |
| 100 | Intentional product misuse | FAERS: 4 | US FAERS | |
| 101 | Lethargy | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 102 | Limb injury | FAERS: 4 | US FAERS | |
| 103 | Lymphadenopathy | FAERS: 4 | US FAERS | |
| 104 | Microcephaly | FAERS: 4 | US FAERS | |
| 105 | Musculoskeletal Pain | FAERS: 4 | US FAERS | |
| 106 | Neutropenia | FAERS: 4 | US FAERS | |
| 107 | Presyncope | FAERS: 4 | US FAERS | |
| 108 | Renal tubular disorder | FAERS: 4 | OFFSIDES US FAERS | |
| 109 | Rhabdomyolysis | FAERS: 4 | OFFSIDES US FAERS | |
| 110 | Swelling | FAERS: 4 | US FAERS | |
| 111 | Thrombosis | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 112 | Wheezing | FAERS: 4 | US FAERS | |
| 113 | Abasia | FAERS: 3 | US FAERS | |
| 114 | Alanine Aminotransferase Increased | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 115 | Angina Pectoris | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 116 | Anosmia | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 117 | Anuria | FAERS: 3 | US FAERS | |
| 118 | Blood urea increased | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 119 | Bronchitis | FAERS: 3 | US FAERS | |
| 120 | Cellulitis | FAERS: 3 | US FAERS | |
| 121 | Colitis | FAERS: 3 | US FAERS | |
| 122 | Congenital cystic kidney disease | FAERS: 3 | US FAERS | |
| 123 | Deafness | FAERS: 3 | US FAERS | |
| 124 | Discomfort | FAERS: 3 | US FAERS | |
| 125 | Expired drug administered | FAERS: 3 | US FAERS | |
| 126 | Familial Tremor | FAERS: 3 | US FAERS | |
| 127 | Flushing | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 128 | Grip strength decreased | FAERS: 3 | US FAERS | |
| 129 | Hepatitis E antibody positive | FAERS: 3 | US FAERS | |
| 130 | Hypersensitivity | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 131 | Implantable defibrillator insertion | FAERS: 3 | US FAERS | |
| 132 | Intestinal Obstruction | FAERS: 3 | US FAERS | |
| 133 | Lip swelling | FAERS: 3 | US FAERS | |
| 134 | Musculoskeletal stiffness | FAERS: 3 | US FAERS | |
| 135 | Myopathy | FAERS: 3 | US FAERS | |
| 136 | Neck Pain | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 137 | Renal cyst | FAERS: 3 | US FAERS | |
| 138 | Rosacea | FAERS: 3 | US FAERS | |
| 139 | Sick Sinus Syndrome | FAERS: 3 | OFFSIDES US FAERS | |
| 140 | Skeletal injury | FAERS: 3 | US FAERS | |
| 141 | Tachycardia | FAERS: 3 | 11518847 | CTD US FAERS |
| 142 | Throat irritation | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 143 | Tremor | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 144 | White blood cell count decreased | FAERS: 3 | US FAERS | |
| 145 | Accidental drug intake by child | FAERS: 2 | US FAERS | |
| 146 | Accidental overdose | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 147 | Activities of daily living impaired | FAERS: 2 | OFFSIDES US FAERS | |
| 148 | Acute myocardial infarction | FAERS: 2 | OFFSIDES US FAERS | |
| 149 | Acute prerenal failure | FAERS: 2 | US FAERS | |
| 150 | Alpha 2 globulin increased | FAERS: 2 | US FAERS | |
| 151 | Aneurysm | FAERS: 2 | US FAERS | |
| 152 | Anhedonia | FAERS: 2 | OFFSIDES US FAERS | |
| 153 | Anorexia | FAERS: 2 | OFFSIDES US FAERS | |
| 154 | Aphonia | FAERS: 2 | US FAERS | |
| 155 | Arteriosclerosis | FAERS: 2 | OFFSIDES US FAERS | |
| 156 | Arthropathy | FAERS: 2 | US FAERS | |
| 157 | Ascites | FAERS: 2 | OFFSIDES US FAERS | |
| 158 | Aspartate Aminotransferase Increased | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 159 | Atrial Fibrillation | FAERS: 2 | US FAERS | |
| 160 | Aura | FAERS: 2 | US FAERS | |
| 161 | Bedridden | FAERS: 2 | US FAERS | |
| 162 | Biliary Dyskinesia | FAERS: 2 | US FAERS | |
| 163 | Blood glucose decreased | FAERS: 2 | OFFSIDES US FAERS | |
| 164 | Blood glucose increased | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 165 | Blood pressure immeasurable | FAERS: 2 | US FAERS | |
| 166 | Bronchopneumonia | FAERS: 2 | US FAERS | |
| 167 | Burning sensation | FAERS: 2 | US FAERS | |
| 168 | Cholangiolitis | FAERS: 2 | OFFSIDES US FAERS | |
| 169 | Chromaturia | FAERS: 2 | US FAERS | |
| 170 | Completed Suicide | FAERS: 2 | US FAERS | |
| 171 | Counterfeit drug administered | FAERS: 2 | US FAERS | |
| 172 | Crying | FAERS: 2 | US FAERS | |
| 173 | Depressed mood | FAERS: 2 | US FAERS | |
| 174 | Diabetic Nephropathy | FAERS: 2 | US FAERS | |
| 175 | Ecchymosis | FAERS: 2 | US FAERS | |
| 176 | Eczema | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 177 | Empyema | FAERS: 2 | US FAERS | |
| 178 | Eosinophilia | FAERS: 2 | US FAERS | |
| 179 | Epstein-Barr virus antibody positive | FAERS: 2 | US FAERS | |
| 180 | Feeling of body temperature change | FAERS: 2 | US FAERS | |
| 181 | Fibromyalgia | FAERS: 2 | US FAERS | |
| 182 | Formication | FAERS: 2 | US FAERS | |
| 183 | Gastritis | FAERS: 2 | US FAERS | |
| 184 | Hemiplegia | FAERS: 2 | US FAERS | |
| 185 | Hepatitis C | FAERS: 2 | US FAERS | |
| 186 | Hernia | FAERS: 2 | OFFSIDES US FAERS | |
| 187 | Hydronephrosis | FAERS: 2 | US FAERS | |
| 188 | Impaired work ability | FAERS: 2 | US FAERS | |
| 189 | Livedo Reticularis | FAERS: 2 | US FAERS | |
| 190 | Lymphopenia | FAERS: 2 | US FAERS | |
| 191 | Macular degeneration | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 192 | Malabsorption | FAERS: 2 | US FAERS | |
| 193 | Meningorrhagia | FAERS: 2 | US FAERS | |
| 194 | Microalbuminuria | FAERS: 2 | US FAERS | |
| 195 | Multiple drug overdose | FAERS: 2 | US FAERS | |
| 196 | Nephritis | FAERS: 2 | US FAERS | |
| 197 | Oliguria | FAERS: 2 | US FAERS | |
| 198 | Ovarian Hyperstimulation Syndrome | FAERS: 2 | OFFSIDES US FAERS | |
| 199 | Paresis | FAERS: 2 | US FAERS | |
| 200 | Patent ductus arteriosus | FAERS: 2 | US FAERS | |
| 201 | Pemphigus | FAERS: 2 | US FAERS | |
| 202 | Peripheral artery thrombosis | FAERS: 2 | US FAERS | |
| 203 | Peripheral swelling | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 204 | Peritoneal Dialysis | FAERS: 2 | US FAERS | |
| 205 | Product substitution issue | FAERS: 2 Canada Vigilance: 73 | Canada Vigilance US FAERS | |
| 206 | Pulmonary Valve Stenosis | FAERS: 2 | US FAERS | |
| 207 | Rash erythematous | FAERS: 2 | US FAERS | |
| 208 | Rectal discharge | FAERS: 2 | US FAERS | |
| 209 | Renal Artery Stenosis | FAERS: 2 | US FAERS | |
| 210 | Renal dysplasia | FAERS: 2 | US FAERS | |
| 211 | Respiratory distress | FAERS: 2 | US FAERS | |
| 212 | Secretion discharge | FAERS: 2 | US FAERS | |
| 213 | Septic Shock | FAERS: 2 | US FAERS | |
| 214 | Sexual Dysfunction | FAERS: 2 | US FAERS | |
| 215 | Shock | FAERS: 2 | US FAERS | |
| 216 | Skin reaction | FAERS: 2 | US FAERS | |
| 217 | Somnambulism | FAERS: 2 | US FAERS | |
| 218 | Stillbirth | FAERS: 2 | US FAERS | |
| 219 | Therapy cessation | FAERS: 2 | US FAERS | |
| 220 | Thrombocytopenia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 221 | Ulcer | FAERS: 2 | US FAERS | |
| 222 | Urinary Incontinence | FAERS: 2 | US FAERS | |
| 223 | Urinary Retention | FAERS: 2 | US FAERS | |
| 224 | Vasculitis | FAERS: 2 | US FAERS | |
| 225 | Venous occlusion | FAERS: 2 | US FAERS | |
| 226 | Wound Infection | FAERS: 2 | US FAERS | |
| 227 | Wrong drug administered | FAERS: 2 | US FAERS | |
| 228 | Ageusia | FAERS: 1 | US FAERS | |
| 229 | Allergy to chemicals | FAERS: 1 | US FAERS | |
| 230 | Angiosclerosis | FAERS: 1 | US FAERS | |
| 231 | Angiotensin converting enzyme inhibitor foetopathy | FAERS: 1 | US FAERS | |
| 232 | Aortic Aneurysm | FAERS: 1 | US FAERS | |
| 233 | Arteritis obliterans | FAERS: 1 | US FAERS | |
| 234 | Atrioventricular Block | FAERS: 1 | OFFSIDES US FAERS | |
| 235 | Autoimmune thrombocytopenia | FAERS: 1 | US FAERS | |
| 236 | Autonomic nervous system imbalance | FAERS: 1 | US FAERS | |
| 237 | Basal cell carcinoma | FAERS: 1 | US FAERS | |
| 238 | Basal ganglia stroke | FAERS: 1 | US FAERS | |
| 239 | Bile Duct Stenosis | FAERS: 1 | US FAERS | |
| 240 | Bipolar Disorder | FAERS: 1 | US FAERS | |
| 241 | Blindness | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 242 | Blood Glucose | FAERS: 1 | US FAERS | |
| 243 | Blood amylase increased | FAERS: 1 | US FAERS | |
| 244 | Blood creatine abnormal | FAERS: 1 | US FAERS | |
| 245 | Blood creatine increased | FAERS: 1 | US FAERS | |
| 246 | Blood creatine phosphokinase MB | FAERS: 1 | US FAERS | |
| 247 | Blood glucose abnormal | FAERS: 1 | US FAERS | |
| 248 | Blood immunoglobulin G increased | FAERS: 1 | US FAERS | |
| 249 | Blood potassium decreased | FAERS: 1 | OFFSIDES US FAERS | |
| 250 | Blood potassium increased | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 251 | Blood sodium decreased | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 252 | Blood triglycerides abnormal | FAERS: 1 | US FAERS | |
| 253 | Blood triglycerides increased | FAERS: 1 | OFFSIDES US FAERS | |
| 254 | Blood urea abnormal | FAERS: 1 | US FAERS | |
| 255 | Bone density decreased | FAERS: 1 | US FAERS | |
| 256 | Bone pain | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 257 | Breast cancer recurrent | FAERS: 1 | US FAERS | |
| 258 | Breast discomfort | FAERS: 1 | US FAERS | |
| 259 | Bronchospasm | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 260 | Bursitis | FAERS: 1 | OFFSIDES US FAERS | |
| 261 | Calcinosis | FAERS: 1 | US FAERS | |
| 262 | Cardiac Flutter | FAERS: 1 | US FAERS | |
| 263 | Carpal Tunnel Syndrome | FAERS: 1 | US FAERS | |
| 264 | Cell Death | FAERS: 1 | US FAERS | |
| 265 | Cerebral calcification | FAERS: 1 | US FAERS | |
| 266 | Chemotherapy | FAERS: 1 | US FAERS | |
| 267 | Choking sensation | FAERS: 1 | US FAERS | |
| 268 | Circumstance or information capable of leading to medication error | FAERS: 1 | US FAERS | |
| 269 | Congenital renal disorder | FAERS: 1 | US FAERS | |
| 270 | Coronary Artery Disease | FAERS: 1 | US FAERS | |
| 271 | Croup infectious | FAERS: 1 | US FAERS | |
| 272 | Cystitis | FAERS: 1 | US FAERS | |
| 273 | Cyst | FAERS: 1 | OFFSIDES US FAERS | |
| 274 | Dehydration | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 275 | Delirium | FAERS: 1 | US FAERS | |
| 276 | Dementia | FAERS: 1 | US FAERS | |
| 277 | Dengue Fever | FAERS: 1 | US FAERS | |
| 278 | Dental caries | FAERS: 1 | US FAERS | |
| 279 | Depression suicidal | FAERS: 1 | US FAERS | |
| 280 | Device breakage | FAERS: 1 | US FAERS | |
| 281 | Diabetes mellitus inadequate control | FAERS: 1 | US FAERS | |
| 282 | Diplopia | FAERS: 1 | US FAERS | |
| 283 | Disease recurrence | FAERS: 1 | US FAERS | |
| 284 | Disorientation | FAERS: 1 | US FAERS | |
| 285 | Drug administration error | FAERS: 1 | US FAERS | |
| 286 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 287 | Duodenitis | FAERS: 1 | US FAERS | |
| 288 | Dysplasia | FAERS: 1 | US FAERS | |
| 289 | Ear discomfort | FAERS: 1 | US FAERS | |
| 290 | Ejection Fraction Decreased | FAERS: 1 | OFFSIDES US FAERS | |
| 291 | Epilepsy | FAERS: 1 | US FAERS | |
| 292 | Epistaxis | FAERS: 1 | OFFSIDES US FAERS | |
| 293 | Epstein-Barr virus antigen positive | FAERS: 1 | US FAERS | |
| 294 | Eructation | FAERS: 1 | US FAERS | |
| 295 | Essential Tremor | FAERS: 1 | US FAERS | |
| 296 | Extremity contracture | FAERS: 1 | US FAERS | |
| 297 | Eye pain | FAERS: 1 | US FAERS | |
| 298 | Eyelid pain | FAERS: 1 | US FAERS | |
| 299 | Facial Paresis | FAERS: 1 | US FAERS | |
| 300 | Facial asymmetry | FAERS: 1 | US FAERS | |
| 301 | Failure to Thrive | FAERS: 1 | US FAERS | |
| 302 | Feeling jittery | FAERS: 1 | US FAERS | |
| 303 | Frustration tolerance decreased | FAERS: 1 | US FAERS | |
| 304 | Gamma-Glutamyltransferase Increased | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance OFFSIDES US FAERS | |
| 305 | Gastrointestinal Pain | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 306 | Gastrointestinal tract adenoma | FAERS: 1 | US FAERS | |
| 307 | Gastrointestinal viral infection | FAERS: 1 | US FAERS | |
| 308 | Gingival Hyperplasia | FAERS: 1 | US FAERS | |
| 309 | Glycosuria | FAERS: 1 | US FAERS | |
| 310 | Granuloma Annulare | FAERS: 1 | US FAERS | |
| 311 | Head circumference abnormal | FAERS: 1 | US FAERS | |
| 312 | Head discomfort | FAERS: 1 | US FAERS | |
| 313 | Helicobacter pylori identification test positive | FAERS: 1 | US FAERS | |
| 314 | Hepatic necrosis | FAERS: 1 | US FAERS | |
| 315 | Hepatitis B antibody positive | FAERS: 1 | US FAERS | |
| 316 | Hepatitis B positive | FAERS: 1 | US FAERS | |
| 317 | Hepatitis E | FAERS: 1 | US FAERS | |
| 318 | Hepatosplenomegaly | FAERS: 1 | US FAERS | |
| 319 | Hernia obstructive | FAERS: 1 | US FAERS | |
| 320 | Hunger | FAERS: 1 | US FAERS | |
| 321 | Hypertrichosis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 322 | Hypospadias | FAERS: 1 | US FAERS | |
| 323 | Immature respiratory system | FAERS: 1 | US FAERS | |
| 324 | Implant site reaction | FAERS: 1 | US FAERS | |
| 325 | Inappropriate schedule of drug administration | FAERS: 1 | US FAERS | |
| 326 | Incorrect storage of drug | FAERS: 1 | US FAERS | |
| 327 | Increased bronchial secretion | FAERS: 1 | US FAERS | |
| 328 | Increased tendency to bruise | FAERS: 1 | US FAERS | |
| 329 | Infection | FAERS: 1 | US FAERS | |
| 330 | Insulin autoimmune syndrome | FAERS: 1 | US FAERS | |
| 331 | Intentional misuse | FAERS: 1 | US FAERS | |
| 332 | Intentional self-injury | FAERS: 1 | US FAERS | |
| 333 | Intervertebral Disc Degeneration | FAERS: 1 | US FAERS | |
| 334 | Intracranial Aneurysm | FAERS: 1 | OFFSIDES US FAERS | |
| 335 | Labile blood pressure | FAERS: 1 | US FAERS | |
| 336 | Laryngitis | FAERS: 1 | US FAERS | |
| 337 | Left Ventricular Hypertrophy | FAERS: 1 | US FAERS | |
| 338 | Leukopenia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 339 | Libido disorder | FAERS: 1 | US FAERS | |
| 340 | Limb discomfort | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 341 | Limb operation | FAERS: 1 | US FAERS | |
| 342 | Limb salvage therapy | FAERS: 1 | US FAERS | |
| 343 | Loose tooth | FAERS: 1 | US FAERS | |
| 344 | Low birth weight baby | FAERS: 1 | US FAERS | |
| 345 | Low set ears | FAERS: 1 | US FAERS | |
| 346 | Lupus Nephritis | FAERS: 1 | US FAERS | |
| 347 | Lymphoma | FAERS: 1 | US FAERS | |
| 348 | MYELODYSPLASTIC SYNDROME | FAERS: 1 | US FAERS | |
| 349 | Macroglossia | FAERS: 1 | OFFSIDES US FAERS | |
| 350 | Male sexual dysfunction | FAERS: 1 | US FAERS | |
| 351 | Medical device complication | FAERS: 1 | US FAERS | |
| 352 | Medication residue | FAERS: 1 | US FAERS | |
| 353 | Mental retardation severity unspecified | FAERS: 1 | US FAERS | |
| 354 | Mental status changes | FAERS: 1 | US FAERS | |
| 355 | Metastasis | FAERS: 1 | US FAERS | |
| 356 | Muscle tightness | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 357 | Musculoskeletal chest pain | FAERS: 1 | US FAERS | |
| 358 | Musculoskeletal discomfort | FAERS: 1 | US FAERS | |
| 359 | Myocarditis | FAERS: 1 | US FAERS | |
| 360 | Nasal inflammation | FAERS: 1 | US FAERS | |
| 361 | Neonatal disorder | FAERS: 1 | US FAERS | |
| 362 | Neonatal hypotension | FAERS: 1 | US FAERS | |
| 363 | Nephrectomy | FAERS: 1 | US FAERS | |
| 364 | Nephrocalcinosis | FAERS: 1 | US FAERS | |
| 365 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 366 | Nerve injury | FAERS: 1 | US FAERS | |
| 367 | Night sweats | FAERS: 1 | US FAERS | |
| 368 | No adverse effect | FAERS: 1 | US FAERS | |
| 369 | No adverse event | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 370 | Obesity | FAERS: 1 | US FAERS | |
| 371 | Oculomucocutaneous syndrome | FAERS: 1 | US FAERS | |
| 372 | Ophthalmoplegia | FAERS: 1 | US FAERS | |
| 373 | Oral pain | FAERS: 1 | US FAERS | |
| 374 | Osteogenesis Imperfecta | FAERS: 1 | US FAERS | |
| 375 | Osteoporosis | FAERS: 1 | OFFSIDES US FAERS | |
| 376 | Otitis Media | FAERS: 1 | US FAERS | |
| 377 | Otosclerosis | FAERS: 1 | US FAERS | |
| 378 | Overweight | FAERS: 1 | US FAERS | |
| 379 | Pancreatic Neoplasm | FAERS: 1 | US FAERS | |
| 380 | Pancytopenia | FAERS: 1 | US FAERS | |
| 381 | Papillary muscle infarction | FAERS: 1 | US FAERS | |
| 382 | Parotid gland inflammation | FAERS: 1 | US FAERS | |
| 383 | Penile curvature | FAERS: 1 | US FAERS | |
| 384 | Periarthritis | FAERS: 1 | US FAERS | |
| 385 | Pericardial effusion | FAERS: 1 | US FAERS | |
| 386 | Periodontitis | FAERS: 1 | US FAERS | |
| 387 | Pharmaceutical product complaint | FAERS: 1 | US FAERS | |
| 388 | Pharyngolaryngeal Pain | FAERS: 1 | US FAERS | |
| 389 | Photodermatosis | FAERS: 1 | US FAERS | |
| 390 | Polychondritis | FAERS: 1 | US FAERS | |
| 391 | Poor quality sleep | FAERS: 1 | US FAERS | |
| 392 | Poor sucking reflex | FAERS: 1 | US FAERS | |
| 393 | Product dispensing error | FAERS: 1 | US FAERS | |
| 394 | Product use issue | FAERS: 1 | US FAERS | |
| 395 | Prostatectomy | FAERS: 1 | US FAERS | |
| 396 | Proteinuria | FAERS: 1 | 15561744 16802178 18175062 | CTD US FAERS |
| 397 | Psoriasis | FAERS: 1 | US FAERS | |
| 398 | Pulmonary Fibrosis | FAERS: 1 | US FAERS | |
| 399 | Pulmonary arterial hypertension | FAERS: 1 | US FAERS | |
| 400 | Pulmonary function test decreased | FAERS: 1 | US FAERS | |
| 401 | Regurgitation | FAERS: 1 | US FAERS | |
| 402 | Renal Cell Carcinoma | FAERS: 1 | US FAERS | |
| 403 | Renal aneurysm | FAERS: 1 | US FAERS | |
| 404 | Renal failure neonatal | FAERS: 1 | US FAERS | |
| 405 | Renal hypertension | FAERS: 1 | US FAERS | |
| 406 | Renal pain | FAERS: 1 | US FAERS | |
| 407 | Renal vessel congenital anomaly | FAERS: 1 | US FAERS | |
| 408 | Restless Legs Syndrome | FAERS: 1 | US FAERS | |
| 409 | Retching | FAERS: 1 | US FAERS | |
| 410 | Rotator cuff syndrome | FAERS: 1 | US FAERS | |
| 411 | Sciatica | FAERS: 1 | US FAERS | |
| 412 | Skin irritation | FAERS: 1 | US FAERS | |
| 413 | Skin lesion | FAERS: 1 | US FAERS | |
| 414 | Sleep disorder due to a general medical condition | FAERS: 1 | US FAERS | |
| 415 | Sneezing | FAERS: 1 | US FAERS | |
| 416 | Spinal column injury | FAERS: 1 | US FAERS | |
| 417 | Sprue-like enteropathy | FAERS: 1 | US FAERS | |
| 418 | Steatohepatitis | FAERS: 1 | US FAERS | |
| 419 | Stevens-Johnson Syndrome | FAERS: 1 | US FAERS | |
| 420 | Stomatitis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 421 | Stress at work | FAERS: 1 | US FAERS | |
| 422 | Temporal Arteritis | FAERS: 1 | US FAERS | |
| 423 | Tension Headache | FAERS: 1 | OFFSIDES US FAERS | |
| 424 | Tension | FAERS: 1 | US FAERS | |
| 425 | Therapeutic response unexpected with drug substitution | FAERS: 1 | US FAERS | |
| 426 | Throat cancer | FAERS: 1 | US FAERS | |
| 427 | Tooth Loss | FAERS: 1 | US FAERS | |
| 428 | Toothache | FAERS: 1 | US FAERS | |
| 429 | Toxicity to various agents | FAERS: 1 | US FAERS | |
| 430 | Transaminases increased | FAERS: 1 | OFFSIDES US FAERS | |
| 431 | Transcription medication error | FAERS: 1 | US FAERS | |
| 432 | Trichorrhexis | FAERS: 1 | US FAERS | |
| 433 | Unequal Limb Length | FAERS: 1 | US FAERS | |
| 434 | Upper respiratory tract congestion | FAERS: 1 | US FAERS | |
| 435 | Urinary Tract Pain | FAERS: 1 | US FAERS | |
| 436 | Urine output increased | FAERS: 1 | US FAERS | |
| 437 | Urticaria | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 438 | VIIth nerve paralysis | FAERS: 1 | US FAERS | |
| 439 | Vasculitic rash | FAERS: 1 | US FAERS | |
| 440 | Venous Thrombosis | FAERS: 1 | US FAERS | |
| 441 | Violence-related symptom | FAERS: 1 | US FAERS | |
| 442 | Vitamin D Deficiency | FAERS: 1 | US FAERS | |
| 443 | Vocal Cord Paralysis | FAERS: 1 | US FAERS | |
| 444 | Wrong technique in product usage process | FAERS: 1 | US FAERS | |
| 445 | colonoscopy | FAERS: 1 | US FAERS | |
| 446 | jaundice | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 447 | muscle injury | FAERS: 1 | US FAERS | |
| 448 | pH urine decreased | FAERS: 1 | US FAERS | |
| 449 | Abdominal Abscess | OFFSIDES | ||
| 450 | Abuse | OFFSIDES | ||
| 451 | Acidosis | OFFSIDES | ||
| 452 | Actinomycosis | OFFSIDES | ||
| 453 | Agranulocytosis | Canada Vigilance: 1 | Canada Vigilance | |
| 454 | Airway burns | Canada Vigilance: 1 | Canada Vigilance | |
| 455 | Alcohol poisoning | OFFSIDES | ||
| 456 | Amylase abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 457 | Apathy | OFFSIDES | ||
| 458 | Application site urticaria | OFFSIDES | ||
| 459 | Arteriovenous graft site infection | OFFSIDES | ||
| 460 | Atherosclerosis | OFFSIDES | ||
| 461 | Atrial tachycardia | OFFSIDES | ||
| 462 | Back disorder | OFFSIDES | ||
| 463 | Bereavement | OFFSIDES | ||
| 464 | Bile duct cancer stage III | OFFSIDES | ||
| 465 | Blepharitis | OFFSIDES | ||
| 466 | Blood alkaline phosphatase increased | Canada Vigilance: 2 | Canada Vigilance OFFSIDES | |
| 467 | Blood bilirubin abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 468 | Blood chloride decreased | OFFSIDES | ||
| 469 | Blood immunoglobulin A increased | OFFSIDES | ||
| 470 | Blood lactate dehydrogenase abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 471 | Blood lactate dehydrogenase increased | OFFSIDES | ||
| 472 | Blood potassium abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 473 | Blood sodium abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 474 | Blood sodium | OFFSIDES | ||
| 475 | Blood thyroid stimulating hormone increased | OFFSIDES | ||
| 476 | Blood urine present | OFFSIDES | ||
| 477 | Bone marrow depression | OFFSIDES | ||
| 478 | Bowel movement irregularity | OFFSIDES | ||
| 479 | Buccal mucosal roughening | OFFSIDES | ||
| 480 | Cardioactive drug level | OFFSIDES | ||
| 481 | Cardiomyopathy, Dilated | 22120037 | CTD | |
| 482 | Cerebral Arteriosclerosis | OFFSIDES | ||
| 483 | Cerebral atrophy | OFFSIDES | ||
| 484 | Charles Bonnet Syndrome | OFFSIDES | ||
| 485 | Chemotherapeutic drug level increased | OFFSIDES | ||
| 486 | Cholecystitis infective | OFFSIDES | ||
| 487 | Clostridium colitis | OFFSIDES | ||
| 488 | Cold sweat | OFFSIDES | ||
| 489 | Colectomy | OFFSIDES | ||
| 490 | Confabulation | OFFSIDES | ||
| 491 | Congenital tricuspid valve incompetence | OFFSIDES | ||
| 492 | Conjunctival deposit | OFFSIDES | ||
| 493 | Cystocele | OFFSIDES | ||
| 494 | Cytomegalovirus test positive | OFFSIDES | ||
| 495 | Deafness Neurosensory | OFFSIDES | ||
| 496 | Decreased Libido | OFFSIDES | ||
| 497 | Dental Fistula | OFFSIDES | ||
| 498 | Dental cleaning | OFFSIDES | ||
| 499 | Dermatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 500 | Diarrhea | OFFSIDES | ||
| 501 | Drowsiness | OFFSIDES | ||
| 502 | Drug ineffective for unapproved indication | Canada Vigilance: 8 | Canada Vigilance | |
| 503 | Dry skin | Canada Vigilance: 2 | Canada Vigilance | |
| 504 | Dyspnoea exacerbated | OFFSIDES | ||
| 505 | Electrocardiogram ST segment abnormal | OFFSIDES | ||
| 506 | Electromechanical dissociation | OFFSIDES | ||
| 507 | Endodontic procedure | OFFSIDES | ||
| 508 | Enterobacter pneumonia | OFFSIDES | ||
| 509 | Erosive gastritis | OFFSIDES | ||
| 510 | Erysipelas | OFFSIDES | ||
| 511 | Facial Neuralgia | OFFSIDES | ||
| 512 | Fistula repair | OFFSIDES | ||
| 513 | Fluid overload | OFFSIDES | ||
| 514 | Foreign body trauma | OFFSIDES | ||
| 515 | Gastric ulcer | OFFSIDES | ||
| 516 | Gastroenteritis | OFFSIDES | ||
| 517 | Gene Mutation | Canada Vigilance: 1 | Canada Vigilance | |
| 518 | Globulinuria | OFFSIDES | ||
| 519 | Glomerulonephritis | 15561744 | CTD | |
| 520 | Heart Diseases | 16923758 | CTD | |
| 521 | Heart failure | 14737854 15167280 15548724 | CTD | |
| 522 | Hemiparesis | OFFSIDES | ||
| 523 | Incontinence | OFFSIDES | ||
| 524 | Increased viscosity of bronchial secretion | Canada Vigilance: 1 | Canada Vigilance | |
| 525 | Infusion site inflammation | OFFSIDES | ||
| 526 | Injection site infection | OFFSIDES | ||
| 527 | Intestinal Perforation | OFFSIDES | ||
| 528 | Iodine uptake increased | OFFSIDES | ||
| 529 | Iridocyclitis | OFFSIDES | ||
| 530 | Joint stiffness | OFFSIDES | ||
| 531 | Kidney Diseases | 16923758 | CTD | |
| 532 | Kidney Failure | OFFSIDES | ||
| 533 | Large intestine perforation | OFFSIDES | ||
| 534 | Leukoencephalopathy | OFFSIDES | ||
| 535 | Ligament injury | OFFSIDES | ||
| 536 | Liver Cirrhosis, Experimental | 14620537 | CTD | |
| 537 | Lyme Disease | OFFSIDES | ||
| 538 | Mastication disorder | OFFSIDES | ||
| 539 | Mechanical ventilation | OFFSIDES | ||
| 540 | Metatarsalgia | OFFSIDES | ||
| 541 | Muscle strain | OFFSIDES | ||
| 542 | Nephritis allergic | OFFSIDES | ||
| 543 | Nephrogenic Fibrosing Dermopathy | OFFSIDES | ||
| 544 | Neurological examination abnormal | OFFSIDES | ||
| 545 | Neutropenic sepsis | OFFSIDES | ||
| 546 | Occult blood positive | OFFSIDES | ||
| 547 | Oral infection | OFFSIDES | ||
| 548 | Osteopenia | OFFSIDES | ||
| 549 | PROTHROMBIN TIME | OFFSIDES | ||
| 550 | Pain of skin | OFFSIDES | ||
| 551 | Paranoia | Canada Vigilance: 1 | Canada Vigilance | |
| 552 | Pelvic prolapse | OFFSIDES | ||
| 553 | Peripheral embolism | OFFSIDES | ||
| 554 | Pharyngeal swelling | Canada Vigilance: 2 | Canada Vigilance | |
| 555 | Physical disability | OFFSIDES | ||
| 556 | Polymyalgia Rheumatica | OFFSIDES | ||
| 557 | Polyneuropathy | OFFSIDES | ||
| 558 | Polysubstance abuse | OFFSIDES | ||
| 559 | Postoperative abscess | OFFSIDES | ||
| 560 | Potentiating drug interaction | OFFSIDES | ||
| 561 | Product lot number issue | Canada Vigilance: 1 | Canada Vigilance | |
| 562 | Product quality issue | Canada Vigilance: 2 | Canada Vigilance | |
| 563 | Product use in unapproved indication | Canada Vigilance: 1 | Canada Vigilance | |
| 564 | Protein total decreased | OFFSIDES | ||
| 565 | Pulmonary Hypertension | OFFSIDES | ||
| 566 | Purulence | OFFSIDES | ||
| 567 | Pyelonephritis | OFFSIDES | ||
| 568 | Radicular pain | OFFSIDES | ||
| 569 | Rales | OFFSIDES | ||
| 570 | Rectocele | OFFSIDES | ||
| 571 | Renal tubular atrophy | OFFSIDES | ||
| 572 | Renal tubular necrosis | OFFSIDES | ||
| 573 | Restrictive pulmonary disease | OFFSIDES | ||
| 574 | Rhabdomyosarcoma | OFFSIDES | ||
| 575 | Rotavirus test positive | OFFSIDES | ||
| 576 | Sequestrectomy | OFFSIDES | ||
| 577 | Shoulder Pain | OFFSIDES | ||
| 578 | Sinobronchitis | OFFSIDES | ||
| 579 | Sinus operation | OFFSIDES | ||
| 580 | Skin hypertrophy | OFFSIDES | ||
| 581 | Spinal column stenosis | OFFSIDES | ||
| 582 | Stridor | OFFSIDES | ||
| 583 | Sudden Cardiac Death | OFFSIDES | ||
| 584 | Supraventricular tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 585 | Synovial Cyst | OFFSIDES | ||
| 586 | Tetany | OFFSIDES | ||
| 587 | Therapeutic product effect decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 588 | Therapeutic response changed | Canada Vigilance: 1 | Canada Vigilance | |
| 589 | Thrombophlebitis | OFFSIDES | ||
| 590 | Tongue biting | OFFSIDES | ||
| 591 | Transferrin decreased | OFFSIDES | ||
| 592 | Ultrasound abdomen abnormal | OFFSIDES | ||
| 593 | Unresponsive to verbal stimuli | OFFSIDES | ||
| 594 | Vascular Remodeling | 25464244 27889505 | CTD | |
| 595 | Vena cava filter insertion | OFFSIDES | ||
| 596 | Ventricular Fibrillation | OFFSIDES | ||
| 597 | Ventricular Remodeling | 27085127 | CTD | |
| 598 | White blood cell count abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 599 | fibroma | OFFSIDES |
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