MetaADEDB 2.0 @ LMMD
Cefadroxil
(BOEGTKLJZSQCCD-UEKVPHQBSA-N)
Structure
SMILES
O=C([C@@H](c1ccc(cc1)O)N)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C
Type(s)
Approved; Vet_approved; Withdrawn
ATC code(s)
J01DB05
Molecular Formula:
C16H17N3O5S
Molecular Weight:
363.388
Log P:
1.1796
Hydrogen Bond Acceptor:
9
Hydrogen Bond Donor:
4
TPSA:
158.26
CAS Number(s):
50370-12-2; 66592-87-8
Synonym(s)
1.
Cefadroxil
2.
4-Hydroxycephalexin
3.
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6R-(6alpha,7beta(R*)))-
4.
BL-S 578
5.
BL-S578
6.
Bidocef
7.
Cefadroxil Anhydrous
8.
Cefadroxil Monohydrate
9.
Cephadroxyl
10.
Duricef
11.
S-578
12.
S578
13.
Ultracef
14.
4 Hydroxycephalexin
15.
BL S 578
16.
BL S578
17.
BLS 578
18.
BLS578
19.
S 578
External Link(s)
MeSHD002434
PubChem Compound6560167
47965
BindingDB50350467
50292250
ChEBI3479
CHEMBLCHEMBL1644
DrugBankDB01140
DrugCentral526
IUPHAR/BPS Guide to PHARMACOLOGY4831
KEGGcpd:C06878
dr:D00257
Therapeutic Target DatabaseD0X9ZC
ZINC3830391
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AngioedemaFAERS: 5SIDER
US FAERS
2ArthralgiaFAERS: 5SIDER
US FAERS
3NauseaFAERS: 5OFFSIDES
SIDER
US FAERS
4UrticariaFAERS: 5
Canada Vigilance: 3		11792017CTD
SIDER
Canada Vigilance
US FAERS
5Chest discomfortFAERS: 4US FAERS
6MyalgiaFAERS: 4US FAERS
7PruritusFAERS: 4
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
8Toxic Epidermal NecrolysisFAERS: 4SIDER
US FAERS
9VomitingFAERS: 4SIDER
US FAERS
10Abdominal discomfortFAERS: 3OFFSIDES
US FAERS
11DizzinessFAERS: 3OFFSIDES
SIDER
US FAERS
12HypersensitivityFAERS: 3SIDER
US FAERS
13MalaiseFAERS: 3
Canada Vigilance: 2		Canada Vigilance
US FAERS
14Alanine Aminotransferase IncreasedFAERS: 2SIDER
US FAERS
15Aspartate Aminotransferase IncreasedFAERS: 2SIDER
US FAERS
16AstheniaFAERS: 2OFFSIDES
SIDER
US FAERS
17Blood alkaline phosphatase increasedFAERS: 2SIDER
US FAERS
18BronchospasmFAERS: 2US FAERS
19DysphoniaFAERS: 2US FAERS
20EpistaxisFAERS: 2OFFSIDES
US FAERS
21ErythemaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
22Feeling abnormalFAERS: 2US FAERS
23Musculoskeletal stiffnessFAERS: 2US FAERS
24Respiratory FailureFAERS: 2OFFSIDES
US FAERS
25ToothacheFAERS: 2US FAERS
26White blood cell count decreasedFAERS: 2US FAERS
27Accidental drug intake by childFAERS: 1US FAERS
28Anaphylactic shockFAERS: 1SIDER
US FAERS
29AnorexiaFAERS: 1OFFSIDES
US FAERS
30ApathyFAERS: 1US FAERS
31ArthritisFAERS: 1OFFSIDES
US FAERS
32ArthropathyFAERS: 1US FAERS
33Back PainFAERS: 1US FAERS
34Burning sensationFAERS: 1US FAERS
35Cardiac TamponadeFAERS: 1US FAERS
36CellulitisFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
37Chest PainFAERS: 1US FAERS
38ChillsFAERS: 1US FAERS
39Coital bleedingFAERS: 1US FAERS
40ColitisFAERS: 1US FAERS
41Collagen-vascular diseaseFAERS: 1US FAERS
42Drug dose omissionFAERS: 1US FAERS
43EczemaFAERS: 1US FAERS
44FatigueFAERS: 1OFFSIDES
US FAERS
45General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
46HyperkeratosisFAERS: 1US FAERS
47MaculeFAERS: 1US FAERS
48Medication ErrorFAERS: 1US FAERS
49Musculoskeletal chest painFAERS: 1OFFSIDES
US FAERS
50Myocardial InfarctionFAERS: 1US FAERS
51PainFAERS: 1OFFSIDES
US FAERS
52PalpitationsFAERS: 1US FAERS
53PericarditisFAERS: 1US FAERS
54PneumoniaFAERS: 1US FAERS
55Protein total decreasedFAERS: 1OFFSIDES
US FAERS
56PurpuraFAERS: 1US FAERS
57Skin test positiveFAERS: 1OFFSIDES
US FAERS
58Stevens-Johnson SyndromeFAERS: 1
Canada Vigilance: 1		25811541CTD
SIDER
Canada Vigilance
US FAERS
59ThirstFAERS: 1US FAERS
60TremorFAERS: 1US FAERS
61UlcerFAERS: 1US FAERS
62Urinary RetentionFAERS: 1US FAERS
63VasculitisFAERS: 1US FAERS
64Wound infection staphylococcalFAERS: 1OFFSIDES
US FAERS
65Abdominal PainOFFSIDES
SIDER
66Abnormal visionOFFSIDES
67AbuseOFFSIDES
68Acid refluxOFFSIDES
69Actinic keratosisOFFSIDES
70ActinomycosisOFFSIDES
71Acute Coronary SyndromeOFFSIDES
72Acute bronchitisOFFSIDES
73AdenomaOFFSIDES
74Adrenal massOFFSIDES
75Adverse eventOFFSIDES
76Agranulocytosis8952318CTD
SIDER
77AgraphiaOFFSIDES
78Allergy to arthropod stingOFFSIDES
79AlopeciaOFFSIDES
80AlveolitisOFFSIDES
81AmnesiaOFFSIDES
82Anemia, Hemolytic8952318CTD
83AneurysmOFFSIDES
84AnhedoniaOFFSIDES
85AnisocoriaOFFSIDES
86AnisocytosisOFFSIDES
87AnxietyOFFSIDES
88Aortic AneurysmOFFSIDES
89Arterial bypass operationOFFSIDES
90ArteriosclerosisOFFSIDES
91Arteriovenous fistula thrombosisOFFSIDES
92ArteritisOFFSIDES
93ArthroscopyOFFSIDES
94AscitesOFFSIDES
95AtelectasisOFFSIDES
96Atrial FlutterOFFSIDES
97Atrial tachycardiaOFFSIDES
98AuraOFFSIDES
99Bacteria urine identifiedOFFSIDES
100Basal cell carcinomaOFFSIDES
101BiopsyOFFSIDES
102Bladder NeoplasmOFFSIDES
103Bladder prolapseOFFSIDES
104BlepharitisOFFSIDES
105BlepharospasmOFFSIDES
106Blood GlucoseOFFSIDES
107Blood albumin decreasedOFFSIDES
108Blood amylase increasedOFFSIDES
109Blood creatinine increasedOFFSIDES
SIDER
110Blood erythropoietin increasedOFFSIDES
111Blood gases abnormalOFFSIDES
112Blood lactate dehydrogenase increasedSIDER
113Blood potassium increasedOFFSIDES
114Blood pressure immeasurableOFFSIDES
115Blood triglycerides increasedOFFSIDES
116Blood urea increasedOFFSIDES
SIDER
117Blurred visionOFFSIDES
118Bone density decreasedOFFSIDES
119Bone fistulaOFFSIDES
120Bone scan abnormalOFFSIDES
121Bone swellingOFFSIDES
122BradycardiaOFFSIDES
123Breech PresentationOFFSIDES
124BronchitisOFFSIDES
125BruxismOFFSIDES
126Buccal mucosal rougheningOFFSIDES
127Candidiasis of vaginaOFFSIDES
128Cardio-respiratory distressOFFSIDES
129Cardioactive drug level above therapeuticOFFSIDES
130Cardioactive drug level increasedOFFSIDES
131CataractOFFSIDES
132Catheter placementOFFSIDES
133Cerebral ArteriosclerosisOFFSIDES
134Cerebral atrophyOFFSIDES
135Chemical and Drug Induced Liver Injury8547737CTD
136Chest wall painOFFSIDES
137Choking sensationOFFSIDES
138CholestasisSIDER
139Chronic Obstructive Airway DiseaseOFFSIDES
140Chronic sinusitisOFFSIDES
141Circumstance or information capable of leading to medication errorOFFSIDES
142Clostridium colitisOFFSIDES
143Colon adenomaOFFSIDES
144ConfabulationOFFSIDES
145Congenital heart diseaseOFFSIDES
146Congenital tricuspid valve incompetenceOFFSIDES
147Conjunctival depositOFFSIDES
148Cor pulmonaleOFFSIDES
149Coronary artery insufficiencyOFFSIDES
150Creatinine increasedSIDER
151CyanosisOFFSIDES
152Deafness NeurosensoryOFFSIDES
153DeafnessOFFSIDES
154DebridementOFFSIDES
155DehydrationOFFSIDES
156DemyelinationOFFSIDES
157Dental abscessOFFSIDES
158Dental cariesOFFSIDES
159Denture wearerOFFSIDES
160Depressed Level of ConsciousnessOFFSIDES
161DermatitisSIDER
162Dermoid CystOFFSIDES
163Device FailureOFFSIDES
164Device occlusionOFFSIDES
165DiabetesOFFSIDES
166Diabetes mellitus inadequate controlOFFSIDES
167DiarrheaOFFSIDES
168DisorientationCanada Vigilance: 1Canada Vigilance
169DiverticulitisOFFSIDES
170DiverticulumOFFSIDES
171DrowsinessSIDER
172Drug Eruptions11792017CTD
173Drug exposure during pregnancyOFFSIDES
174Drug toxicityOFFSIDES
175Drug withdrawal convulsionsOFFSIDES
176Drug withdrawal headacheOFFSIDES
177DuodenitisOFFSIDES
178DysgeusiaOFFSIDES
179DyspepsiaOFFSIDES
SIDER
180DysphasiaOFFSIDES
181DysphemiaOFFSIDES
182Dysthymic DisorderOFFSIDES
183DystoniaCanada Vigilance: 1Canada Vigilance
184DysuriaOFFSIDES
185Ear dischargeOFFSIDES
186Economic problemOFFSIDES
187Ejection Fraction DecreasedOFFSIDES
188Electrocardiogram ST-T changeOFFSIDES
189Emotional disorderOFFSIDES
190Emotional distressOFFSIDES
191Endodontic procedureOFFSIDES
192EosinophiliaSIDER
193EpicondylitisOFFSIDES
194Erythema MultiformeSIDER
195Escherichia coli Infections8225621CTD
196Escherichia infectionOFFSIDES
197Ethmoid sinus surgeryOFFSIDES
198Eustachian tube disorderOFFSIDES
199ExophthalmosOFFSIDES
200Exposure to toxic agentOFFSIDES
201Eyelid DiseasesOFFSIDES
202Failure to ThriveOFFSIDES
203Fatty LiverOFFSIDES
204Feeling ColdOFFSIDES
205Femoral artery occlusionOFFSIDES
206Fever6124751CTD
207FibromyalgiaOFFSIDES
208Flank PainOFFSIDES
209Fluid overloadOFFSIDES
210FlushingCanada Vigilance: 1Canada Vigilance
211Foreign body traumaOFFSIDES
212Gastrointestinal PainSIDER
213Gastrointestinal tract adenomaOFFSIDES
214General physical conditionOFFSIDES
215GlaucomaOFFSIDES
216GoiterOFFSIDES
217GranulocytosisOFFSIDES
218HeadacheSIDER
219Hearing aid userOFFSIDES
220Helicobacter pylori identification test positiveOFFSIDES
221Hepatojugular refluxOFFSIDES
222HerniaOFFSIDES
223HomicideOFFSIDES
224HydronephrosisOFFSIDES
225HydrothoraxOFFSIDES
226Hypersplenism acquiredOFFSIDES
227HyperventilationOFFSIDES
228Hypoaesthesia facialOFFSIDES
229HypophagiaOFFSIDES
230HypoxiaOFFSIDES
231Idiopathic urticariaOFFSIDES
232IncontinenceOFFSIDES
233Incorrect route of drug administrationOFFSIDES
234InfectionOFFSIDES
235InfertilitySIDER
236Infusion site mobility decreasedOFFSIDES
237Injection site infectionOFFSIDES
238Intentional drug misuseOFFSIDES
239Intentional self-injuryOFFSIDES
240Intermittent ClaudicationOFFSIDES
241Intervertebral Disc DegenerationOFFSIDES
242Intestinal PerforationOFFSIDES
243Joint Range of Motion DecreasedOFFSIDES
244Joint stiffnessOFFSIDES
245Jugular vein distensionOFFSIDES
246Keratitis siccaOFFSIDES
247LacerationOFFSIDES
248Lactic dehydrogenase activity increasedSIDER
249Left Ventricular HypertrophyOFFSIDES
250LethargyOFFSIDES
251Leukopenia neonatalOFFSIDES
252Life expectancy shortenedOFFSIDES
253Light chain diseaseOFFSIDES
254Limb injuryOFFSIDES
255Lip swellingCanada Vigilance: 1Canada Vigilance
256Livedo ReticularisOFFSIDES
257Loose toothOFFSIDES
258Lung hyperinflationOFFSIDES
259LymphangitisOFFSIDES
260LymphedemaOFFSIDES
261Lymphocytic infiltrationOFFSIDES
262LymphomaOFFSIDES
263Malignant neoplasm progressionOFFSIDES
264Mammary duct ectasiaOFFSIDES
265MastectomyOFFSIDES
266Mastication disorderOFFSIDES
267Maxillofacial operationOFFSIDES
268MeningiomaOFFSIDES
269Mental status changesOFFSIDES
270Metabolic acidosisOFFSIDES
271Metastatic NeoplasmOFFSIDES
272Micrographic skin surgeryOFFSIDES
273Multiple SclerosisOFFSIDES
274Muscle RigidityCanada Vigilance: 1Canada Vigilance
275Muscle WeaknessOFFSIDES
276Muscle strainOFFSIDES
277Musculoskeletal PainOFFSIDES
278Musculoskeletal discomfortSIDER
279Myocarditis11064276CTD
280NephrolithiasisOFFSIDES
281NervousnessSIDER
282NeutropeniaSIDER
283Neutropenic sepsisOFFSIDES
284NocturiaOFFSIDES
285NoduleOFFSIDES
286Non-cardiac chest painOFFSIDES
287Occult blood positiveOFFSIDES
288OliguriaOFFSIDES
289Oral fungal infectionOFFSIDES
290Oral mucosal erythemaOFFSIDES
291Oral torusOFFSIDES
292Oropharyngeal painOFFSIDES
293OrthopneaOFFSIDES
294OsteomyelitisOFFSIDES
295OsteopeniaOFFSIDES
296OsteosclerosisOFFSIDES
297PCO2 increasedOFFSIDES
298PallorOFFSIDES
299PancreatitisOFFSIDES
300PancytopeniaSIDER
301Panic DisorderOFFSIDES
302Pelvic InfectionOFFSIDES
303Pelvic abscessOFFSIDES
304Perianal abscessOFFSIDES
305PeritonitisOFFSIDES
306Pharyngolaryngeal PainOFFSIDES
307PhlebitisOFFSIDES
308Physical assaultOFFSIDES
309Physical disabilityOFFSIDES
310Pilonidal cyst congenitalOFFSIDES
311PlasmapheresisOFFSIDES
312PoikilocytosisOFFSIDES
313PolyuriaOFFSIDES
314Portal HypertensionOFFSIDES
315Postoperative infectionOFFSIDES
316Primary sequestrumOFFSIDES
317Productive CoughOFFSIDES
318Prolapse repairOFFSIDES
319Pulmonary HypertensionOFFSIDES
320Pulmonary InfarctionOFFSIDES
321Pulmonary Valve StenosisOFFSIDES
322Pulmonary radiation injuryOFFSIDES
323Purulent dischargeOFFSIDES
324Radicular painOFFSIDES
325Rectal ProlapseOFFSIDES
326Renal cystOFFSIDES
327Renal lipomatosisOFFSIDES
328Respiratory Tract Infections11064276CTD
329Retinal VasculitisOFFSIDES
330RhinitisOFFSIDES
331RhonchiOFFSIDES
332Right atrial dilatationOFFSIDES
333Right ventricle outflow tract obstructionOFFSIDES
334Salpingitis6124751CTD
335Serum SicknessOFFSIDES
SIDER
336Sexual abuseOFFSIDES
337Sinus antrostomyOFFSIDES
338Sinus painOFFSIDES
339SinusitisOFFSIDES
340Skin lacerationOFFSIDES
341Skin neoplasm excisionOFFSIDES
342SomnolenceSIDER
343StomatitisCanada Vigilance: 1Canada Vigilance
344StressOFFSIDES
345Subcutaneous noduleOFFSIDES
346SuperinfectionSIDER
347Sweat gland infectionOFFSIDES
348SwellingSIDER
349SymblepharonOFFSIDES
350Temperature intoleranceOFFSIDES
351TensionSIDER
352Thirst decreasedOFFSIDES
353ThrombocytopeniaSIDER
354Tinea crurisOFFSIDES
355TinnitusOFFSIDES
356Tooth ExtractionOFFSIDES
357Unevaluable eventOFFSIDES
358Unresponsive to stimuliOFFSIDES
359Urine leukocyte esteraseOFFSIDES
360Uterine CancerOFFSIDES
361Uterovaginal prolapseOFFSIDES
362Venous InsufficiencyOFFSIDES
363VertigoSIDER
364Vestibular NeuronitisOFFSIDES
365Weight GainOFFSIDES
366Wound decompositionOFFSIDES
367Wound infection pseudomonasOFFSIDES
368XerosisOFFSIDES
369kyphosisOFFSIDES
370pseudomembranous colitisSIDER
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