MetaADEDB 2.0 @ LMMD
Oxaprozin
(OFPXSFXSNFPTHF-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)CCc1nc(c(o1)c1ccccc1)c1ccccc1
Type(s)
Approved
ATC code(s)
M01AE12
Molecular Formula:
C18H15NO3
Molecular Weight:
293.317
Log P:
4.0258
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
63.33
CAS Number(s):
21256-18-8
Synonym(s)
1.
Oxaprozin
2.
4,5-Diphenyl-2-oxazolepropionic Acid
3.
Apo-Oxaprozin
4.
Danoprox
5.
Daypro
6.
Dayrun
7.
Rhoxal-oxaprozin
8.
Wy-21,743
9.
4,5 Diphenyl 2 oxazolepropionic Acid
10.
Apo Oxaprozin
11.
Rhoxal oxaprozin
12.
Wy 21,743
External Link(s)
MeSHD000077431
PubChem Compound4614
BindingDB50002861
ChEBI7822
CHEMBLCHEMBL1071
DrugBankDB00991
DrugCentral2013
IUPHAR/BPS Guide to PHARMACOLOGY7252
KEGGcpd:C07356
dr:D00463
Therapeutic Target DatabaseD0M9DC
ZINC49643479
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 25OFFSIDES
US FAERS
2UrticariaFAERS: 19SIDER
US FAERS
3DizzinessFAERS: 9SIDER
US FAERS
4HypersensitivityFAERS: 9US FAERS
5Abdominal discomfortFAERS: 8OFFSIDES
US FAERS
6NauseaFAERS: 7
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
7PruritusFAERS: 6SIDER
US FAERS
8MalaiseFAERS: 5SIDER
US FAERS
9Stevens-Johnson SyndromeFAERS: 525811541CTD
SIDER
US FAERS
10SwellingFAERS: 5US FAERS
11Chest PainFAERS: 4OFFSIDES
US FAERS
12Feeling abnormalFAERS: 4SIDER
US FAERS
13HeadacheFAERS: 4SIDER
US FAERS
14PainFAERS: 4OFFSIDES
US FAERS
15TorticollisFAERS: 4US FAERS
16HepatitisFAERS: 310492496CTD
SIDER
US FAERS
17Product use issueFAERS: 3US FAERS
18Toxic Epidermal NecrolysisFAERS: 3SIDER
US FAERS
19VomitingFAERS: 3SIDER
US FAERS
20ArthralgiaFAERS: 2US FAERS
21AstheniaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
22ConstipationFAERS: 2SIDER
US FAERS
23Drug screen false positiveFAERS: 2US FAERS
24DyspepsiaFAERS: 2OFFSIDES
SIDER
US FAERS
25ErythemaFAERS: 2OFFSIDES
US FAERS
26FatigueFAERS: 2OFFSIDES
US FAERS
27FlushingFAERS: 2US FAERS
28Gastric ulcerFAERS: 2OFFSIDES
US FAERS
29HypotensionFAERS: 2SIDER
US FAERS
30Lip swellingFAERS: 2US FAERS
31PalpitationsFAERS: 2SIDER
US FAERS
32PancreatitisFAERS: 2OFFSIDES
SIDER
US FAERS
33Product quality issueFAERS: 2US FAERS
34Product substitution issueFAERS: 2US FAERS
35Product use in unapproved indicationFAERS: 2US FAERS
36Therapeutic response unexpected with drug substitutionFAERS: 2US FAERS
37TremorFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
38Weight decreasedFAERS: 2US FAERS
39AgitationFAERS: 1US FAERS
40Alanine Aminotransferase IncreasedFAERS: 1US FAERS
41AlopeciaFAERS: 1OFFSIDES
SIDER
US FAERS
42AngioedemaFAERS: 1SIDER
US FAERS
43Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
44BlindnessFAERS: 1US FAERS
45Blood count abnormalFAERS: 1OFFSIDES
US FAERS
46Blood urine presentFAERS: 1OFFSIDES
US FAERS
47Burning sensationFAERS: 1US FAERS
48Chest discomfortFAERS: 1US FAERS
49ChillsFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
50Conjunctival scarFAERS: 1US FAERS
51ConjunctivitisFAERS: 1SIDER
US FAERS
52Corneal OpacityFAERS: 1US FAERS
53Diabetes MellitusFAERS: 1US FAERS
54DiscomfortFAERS: 1SIDER
US FAERS
55Drug effect incompleteFAERS: 1US FAERS
56Drug screen positiveFAERS: 1US FAERS
57DysarthriaFAERS: 1US FAERS
58DysphasiaFAERS: 1US FAERS
59DysphemiaFAERS: 1US FAERS
60Electrocardiogram abnormalFAERS: 1US FAERS
61EndometriosisFAERS: 1US FAERS
62EntropionFAERS: 1US FAERS
63EpistaxisFAERS: 1OFFSIDES
US FAERS
64Febrile NeutropeniaFAERS: 1US FAERS
65Feeling of body temperature changeFAERS: 1US FAERS
66GastritisFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
67Gastrointestinal ulcerFAERS: 1SIDER
US FAERS
68Hepatic necrosisFAERS: 1US FAERS
69HypersomniaFAERS: 1US FAERS
70Intentional product misuseFAERS: 1US FAERS
71Joint stiffnessFAERS: 1US FAERS
72LeukopeniaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
73MyalgiaFAERS: 1US FAERS
74Myocardial InfarctionFAERS: 1SIDER
US FAERS
75MyositisFAERS: 1US FAERS
76Night sweatsFAERS: 1US FAERS
77Pharmaceutical product complaintFAERS: 1US FAERS
78Pharyngolaryngeal PainFAERS: 1US FAERS
79Quality of life decreasedFAERS: 1US FAERS
80Refusal of treatment by relativeFAERS: 1US FAERS
81Restless Legs SyndromeFAERS: 1US FAERS
82Rheumatoid ArthritisFAERS: 1US FAERS
83ShockFAERS: 1SIDER
US FAERS
84SymblepharonFAERS: 1US FAERS
85TrichiasisFAERS: 1US FAERS
86AbasiaOFFSIDES
87Abdominal PainOFFSIDES
SIDER
88Abdominal adhesionsOFFSIDES
89AbscessOFFSIDES
90Accidental exposureOFFSIDES
91Acid refluxOFFSIDES
92Activities of daily living impairedOFFSIDES
93Acute Coronary SyndromeSIDER
94Acute bronchitisOFFSIDES
95Acute interstitial nephritisSIDER
96Acute myocardial infarctionOFFSIDES
97Acute prerenal failureOFFSIDES
98AdenocarcinomaOFFSIDES
99AgranulocytosisSIDER
100Altered bowel functionOFFSIDES
101AlveolitisOFFSIDES
102Amaurosis FugaxOFFSIDES
103AmphetaminesOFFSIDES
104AnalgesiaOFFSIDES
105Anaphylactic shockSIDER
106Anaphylactoid ReactionSIDER
107AngerOFFSIDES
108AnhidrosisOFFSIDES
109AnorexiaOFFSIDES
SIDER
110Anoxic EncephalopathyOFFSIDES
111Anticholinergic SyndromeOFFSIDES
112AnxietyOFFSIDES
SIDER
113Aortic valve sclerosisOFFSIDES
114AppendicitisOFFSIDES
115ArteriosclerosisOFFSIDES
116ArthritisOFFSIDES
117ArthropathyOFFSIDES
118Arthropod biteOFFSIDES
119Aspiration PneumoniaOFFSIDES
120AsthmaOFFSIDES
SIDER
121AtelectasisOFFSIDES
122Atrial tachycardiaOFFSIDES
123AuraOFFSIDES
124B-cell lymphoma stage IOFFSIDES
125Bacterial Infections12669766CTD
126Basal cell carcinomaOFFSIDES
127Benign Prostatic HyperplasiaOFFSIDES
128Biopsy bladder abnormalOFFSIDES
129Biopsy liver abnormalOFFSIDES
130Bipolar DisorderOFFSIDES
131Bladder painSIDER
132BlepharitisOFFSIDES
133Blood GlucoseOFFSIDES
134Blood cholesterolOFFSIDES
135Blood creatine phosphokinase increasedOFFSIDES
136Blood immunoglobulin A increasedOFFSIDES
137Blood pH decreasedOFFSIDES
138Blood testosterone decreasedOFFSIDES
139Blood triglycerides increasedOFFSIDES
140Blurred visionOFFSIDES
141Bone density decreasedOFFSIDES
142Bone erosionOFFSIDES
143Bone fragmentationOFFSIDES
144Bone lesionOFFSIDES
145Bone scan abnormalOFFSIDES
146BursitisOFFSIDES
147CalcinosisOFFSIDES
148Carotid artery occlusionOFFSIDES
149CataractOFFSIDES
150CellulitisOFFSIDES
151Cerebral ArteriosclerosisOFFSIDES
152Chemical and Drug Induced Liver Injury7841569
10492496		CTD
153Chest wall painOFFSIDES
154Choking sensationOFFSIDES
155ChondrosisOFFSIDES
156Chronic Obstructive Airway DiseaseOFFSIDES
157Chronic ulcerative colitisOFFSIDES
158ColitisOFFSIDES
159Colon adenomaOFFSIDES
160Concomitant disease progressionOFFSIDES
161ConfabulationOFFSIDES
162Congenital tricuspid valve incompetenceOFFSIDES
163Conjunctival depositOFFSIDES
164Corneal dystrophyOFFSIDES
165Coronary artery embolismOFFSIDES
166Creutzfeldt-Jakob diseaseOFFSIDES
167CryotherapyOFFSIDES
168CystitisSIDER
169CystOFFSIDES
170DeafnessSIDER
171DebridementOFFSIDES
172Decreased LibidoOFFSIDES
173DehydrationOFFSIDES
174DemyelinationOFFSIDES
175Dental discomfortOFFSIDES
176Denture wearerOFFSIDES
177DermatitisSIDER
178DiabetesOFFSIDES
179Diabetic NephropathyOFFSIDES
180Diabetic RetinopathyOFFSIDES
181DiarrheaOFFSIDES
182Diastolic dysfunctionOFFSIDES
183Dihydrotestosterone decreasedOFFSIDES
184Disease ProgressionOFFSIDES
185Disease recurrenceOFFSIDES
186DistressSIDER
187DiuresisSIDER
188DiverticulitisOFFSIDES
189DiverticulumOFFSIDES
190DrowsinessSIDER
191Drug ToleranceOFFSIDES
192Drug abuserOFFSIDES
193Drug addictOFFSIDES
194Drug dispensing errorOFFSIDES
195Drug toxicityOFFSIDES
196Drug withdrawal headacheOFFSIDES
197Dry skinOFFSIDES
198DysgeusiaOFFSIDES
SIDER
199Dysthymic DisorderOFFSIDES
200DystoniaOFFSIDES
201DysuriaOFFSIDES
SIDER
202EcchymosisSIDER
203Economic problemOFFSIDES
204Emotional disorderOFFSIDES
205Emotional distressOFFSIDES
SIDER
206EncephalitisOFFSIDES
207Endometrial hypertrophyOFFSIDES
208EosinophiliaSIDER
209Epigastric painSIDER
210Erectile dysfunctionOFFSIDES
211EructationSIDER
212Erythema MultiformeSIDER
213Essential HypertensionOFFSIDES
214Fatty LiverOFFSIDES
215FibromyalgiaOFFSIDES
216Flank PainOFFSIDES
217Flat affectOFFSIDES
218FlatulenceOFFSIDES
SIDER
219Fluid replacementOFFSIDES
220FolliculitisOFFSIDES
221GastroenteritisOFFSIDES
222Gastrointestinal PainSIDER
223Genital infection fungalOFFSIDES
224Gingival erythemaOFFSIDES
225GlobulinuriaOFFSIDES
226GlossitisSIDER
227GoiterOFFSIDES
228GoutOFFSIDES
229Hay feverOFFSIDES
230HeartburnSIDER
231HordeolumOFFSIDES
232HostilityOFFSIDES
233HydronephrosisOFFSIDES
234HyperkeratosisOFFSIDES
235Hypertensive cardiomyopathyOFFSIDES
236Hypertensive heart diseaseOFFSIDES
237Hypertrophic CardiomyopathyOFFSIDES
238HypophagiaOFFSIDES
239HypoxiaOFFSIDES
240IleitisOFFSIDES
241Impaired gastric emptyingOFFSIDES
242Impaired work abilityOFFSIDES
243ImpetigoOFFSIDES
244InfectionSIDER
245Inflammation15934904CTD
246Infusion site mobility decreasedOFFSIDES
247Injection site erythemaOFFSIDES
248Injection site pruritusOFFSIDES
249Injection site stingingOFFSIDES
250Injection site warmthOFFSIDES
251Insulin-requiring type 2 diabetes mellitusOFFSIDES
252Intention tremorOFFSIDES
253Intentional self-injuryOFFSIDES
254Intervertebral Disc DegenerationOFFSIDES
255Intestinal ObstructionOFFSIDES
256Joint sprainOFFSIDES
257Kidney FailureOFFSIDES
258LacerationOFFSIDES
259LaparotomyOFFSIDES
260Large intestine perforationOFFSIDES
261LethargyOFFSIDES
SIDER
262Leukopenia neonatalOFFSIDES
263Ligament ruptureOFFSIDES
264Limb injuryOFFSIDES
265Liver Failure, Acute7841569CTD
266Lymph nodes scan abnormalOFFSIDES
267LymphadenopathySIDER
268Malignant neoplasm progressionOFFSIDES
269Mass excisionOFFSIDES
270MeningitisSIDER
271Meniscus operationOFFSIDES
272Mental impairmentOFFSIDES
273Mental status changesOFFSIDES
274MononeuritisOFFSIDES
275Multi-organ disorderOFFSIDES
276Multiple MyelomaOFFSIDES
277Muscle strainOFFSIDES
278Muscle tightnessOFFSIDES
279Musculoskeletal PainOFFSIDES
280Musculoskeletal chest painOFFSIDES
281Musculoskeletal stiffnessOFFSIDES
282Myoglobin urine presentOFFSIDES
283Nail InfectionOFFSIDES
284Nephrotic SyndromeSIDER
285Nervous tensionOFFSIDES
286NervousnessSIDER
287NeuralgiaOFFSIDES
288NeutropeniaCanada Vigilance: 1Canada Vigilance
289NocturiaOFFSIDES
290NoduleOFFSIDES
291NystagmusOFFSIDES
292OliguriaSIDER
293Osteitis DeformansOFFSIDES
294OsteomyelitisOFFSIDES
295OsteopeniaOFFSIDES
296OsteoporosisOFFSIDES
297PancytopeniaSIDER
298Panic DisorderOFFSIDES
299ParanoiaOFFSIDES
300Pathogen resistanceOFFSIDES
301Peptic UlcerSIDER
302PeriarthritisOFFSIDES
303Physical disabilityOFFSIDES
304PleuropericarditisOFFSIDES
305PneumoniaSIDER
306Polymyalgia RheumaticaOFFSIDES
307Polysubstance abuseOFFSIDES
308PolyuriaSIDER
309Postoperative ileusOFFSIDES
310PresbyopiaOFFSIDES
311Procedural complicationOFFSIDES
312Protein total increasedOFFSIDES
313Protein urine presentSIDER
314ProteinuriaSIDER
315PseudoporphyriaSIDER
316PsoriasisOFFSIDES
317Pulmonary InfarctionOFFSIDES
318Pulmonary function test decreasedSIDER
319PurpuraSIDER
320Pyoderma GangrenosumOFFSIDES
321PyuriaOFFSIDES
322QuadriparesisOFFSIDES
323Respiratory DepressionSIDER
324Respiratory FailureOFFSIDES
325RetrocollisOFFSIDES
326Rheumatoid NoduleOFFSIDES
327RhinitisOFFSIDES
328RhonchiOFFSIDES
329SacroiliitisOFFSIDES
330SarcoidosisOFFSIDES
331ScabOFFSIDES
332SchizophreniaOFFSIDES
333School refusalOFFSIDES
334Self-induced vomitingOFFSIDES
335SepsisSIDER
336Serum SicknessSIDER
337SinusitisOFFSIDES
SIDER
338Skin lacerationOFFSIDES
339Skin lesionOFFSIDES
340SomnolenceSIDER
341Spinal column stenosisOFFSIDES
342StomatitisSIDER
343SyncopeSIDER
344SyphilisOFFSIDES
345TachycardiaSIDER
346Tardive DyskinesiaOFFSIDES
347TensionSIDER
348Therapeutic procedureOFFSIDES
349ThrombocytopeniaSIDER
350ThrombophlebitisOFFSIDES
351Tinea crurisOFFSIDES
352TinnitusOFFSIDES
SIDER
353Toe operationOFFSIDES
354Tooth ExtractionOFFSIDES
355Tooth InfectionOFFSIDES
356Tooth LossOFFSIDES
357UlcerSIDER
358Upper respiratory tract signs and symptomsSIDER
359Urethral strictureOFFSIDES
360Urine flow decreasedOFFSIDES
361Urine output increasedSIDER
362Vascular purpuraSIDER
363VasculitisSIDER
364Vena cava filter insertionOFFSIDES
365Ventricular hypokinesiaOFFSIDES
366VertigoSIDER
367Viral pharyngitisOFFSIDES
368Visual ImpairmentCanada Vigilance: 1Canada Vigilance
369Visual disturbanceOFFSIDES
370Weight GainOFFSIDES
371Wound abscessOFFSIDES
372effusionOFFSIDES
373jaundice10492496CTD
SIDER
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