MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Iridocyclitis

(UMLS:C0022073)

Definition:: Acute or chronic inflammation of the iris and ciliary body characterized by exudates into the anterior chamber, discoloration of the iris, and constricted, sluggish pupil. Symptoms include radiating pain, photophobia, lacrimation, and interference with vision.
UMLS ID:: C0022073
MeSH ID:: D015863

Classification:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.941.375.360|C11.941.879.780.880.400

Synonym(s)

Iridocyclitis

Inflammation of iris and ciliary body

Iridocyclitis, NOS

Iridocyclitis, unspecified

Unspecified iridocyclitis

iridocyclitis

iridocyclitis was observed

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Zoledronic Acid	FAERS: 45 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
2	Topiramate	FAERS: 43		US FAERS
3	Moxifloxacin	FAERS: 42		US FAERS
4	Fingolimod Hydrochloride	FAERS: 10		US FAERS
5	Mitomycin	FAERS: 10		OFFSIDES US FAERS
6	Latanoprost	FAERS: 9		US FAERS
7	Lamotrigine	FAERS: 8		US FAERS
8	Vemurafenib	FAERS: 8		US FAERS
9	Brimonidine Tartrate, Timolol Maleate Drug Combination	FAERS: 6		US FAERS
10	Erlotinib Hydrochloride	FAERS: 6		US FAERS
11	Cyclosporine	FAERS: 5		US FAERS
12	Trimethoprim	FAERS: 5		US FAERS
13	Clomiphene	FAERS: 4		OFFSIDES US FAERS
14	Methotrexate	FAERS: 4		US FAERS
15	Terbinafine	FAERS: 4		OFFSIDES US FAERS
16	Azathioprine	FAERS: 3		US FAERS
17	Brimonidine Tartrate	FAERS: 3		US FAERS
18	Brimonidine Tartrate	FAERS: 3		OFFSIDES SIDER US FAERS
19	Dexamethasone	FAERS: 3		US FAERS
20	Ibuprofen	FAERS: 3		US FAERS
21	Acyclovir	FAERS: 2		US FAERS
22	Bimatoprost	FAERS: 2		OFFSIDES US FAERS
23	Capecitabine	FAERS: 2		US FAERS
24	Chloramphenicol	FAERS: 2		US FAERS
25	Cidofovir	FAERS: 2		OFFSIDES SIDER US FAERS
26	Clarithromycin	FAERS: 2		US FAERS
27	Ganfort	FAERS: 2		US FAERS
28	Glatiramer Acetate	FAERS: 2		US FAERS
29	Imatinib Mesylate	FAERS: 2		US FAERS
30	Naproxen	FAERS: 2		US FAERS
31	PCI 32765	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
32	Rivaroxaban	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
33	Simbrinza	FAERS: 2		US FAERS
34	Valacyclovir	FAERS: 2		US FAERS
35	fludarabine phosphate	FAERS: 2		OFFSIDES US FAERS
36	ledipasvir, sofosbuvir drug combination	FAERS: 2		US FAERS
37	levocetirizine	FAERS: 2		US FAERS
38	lifitegrast	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
39	teriflunomide	FAERS: 2		US FAERS
40	Alendronate	FAERS: 1		US FAERS
41	Alendronate	FAERS: 1		US FAERS
42	Amlodipine	FAERS: 1		US FAERS
43	Aspirin	FAERS: 1		US FAERS
44	Atomoxetine Hydrochloride	FAERS: 1		US FAERS
45	Axitinib	FAERS: 1		US FAERS
46	Celecoxib	FAERS: 1		US FAERS
47	Ciprofloxacin	FAERS: 1		US FAERS
48	Fluocinolone Acetonide	FAERS: 1		US FAERS
49	Fosamax plus D	FAERS: 1		US FAERS
50	Hydroxychloroquine	FAERS: 1		US FAERS
51	Interleukin 1 Receptor Antagonist Protein	FAERS: 1		US FAERS
52	Isotretinoin	FAERS: 1		US FAERS
53	Lopinavir	FAERS: 1		US FAERS
54	Methadone	FAERS: 1		US FAERS
55	Methylphenidate	FAERS: 1		US FAERS
56	Mycophenolic Acid	FAERS: 1		US FAERS
57	Nitrofurantoin	FAERS: 1		OFFSIDES US FAERS
58	Octreotide	FAERS: 1		US FAERS
59	Odefsey	FAERS: 1		US FAERS
60	Olmesartan Medoxomil	FAERS: 1		US FAERS
61	Olopatadine Hydrochloride	FAERS: 1		US FAERS
62	Pamidronate	FAERS: 1		US FAERS
63	Paroxetine	FAERS: 1		US FAERS
64	Restasis	FAERS: 1		US FAERS
65	Risedronic Acid	FAERS: 1		US FAERS
66	Risedronic Acid	FAERS: 1		US FAERS
67	Sitagliptin Phosphate	FAERS: 1		US FAERS
68	Sunitinib	FAERS: 1		US FAERS
69	Tenofovir	FAERS: 1		OFFSIDES US FAERS
70	Travoprost	FAERS: 1		SIDER US FAERS
71	Triamcinolone Acetonide	FAERS: 1		US FAERS
72	Umeclidinium bromide	FAERS: 1		US FAERS
73	dabrafenib	FAERS: 1		US FAERS
74	exemestane	FAERS: 1		US FAERS
75	levocetirizine	FAERS: 1		US FAERS
76	liposomal amphotericin B	FAERS: 1		US FAERS
77	palbociclib	FAERS: 1		US FAERS
78	prednisolone acetate	FAERS: 1	11004305	CTD OFFSIDES US FAERS
79	Acetazolamide			OFFSIDES
80	Azelaic acid			SIDER
81	Budesonide			OFFSIDES
82	Chlorhexidine			OFFSIDES
83	Cyclopentolate		11004305	CTD OFFSIDES SIDER
84	Cyclophosphamide			OFFSIDES
85	Cyproterone Acetate			OFFSIDES
86	Cytarabine			OFFSIDES
87	Disopyramide			OFFSIDES
88	Epinephrine			OFFSIDES
89	Erlotinib Hydrochloride			OFFSIDES
90	Ethambutol			OFFSIDES
91	Fluorometholone			OFFSIDES SIDER
92	Fluvoxamine			OFFSIDES
93	Ganciclovir			OFFSIDES
94	Gatifloxacin			OFFSIDES
95	Ivermectin			SIDER
96	Leflunomide			OFFSIDES
97	Letrozole			OFFSIDES
98	Levobunolol			OFFSIDES SIDER
99	Methylprednisolone Acetate			OFFSIDES
100	Minoxidil			OFFSIDES
101	Nelfinavir			OFFSIDES
102	Neomycin			OFFSIDES
103	Nicergoline			OFFSIDES
104	Nifedipine			OFFSIDES
105	Pamidronate			OFFSIDES SIDER
106	Phenylephrine		11037905	CTD
107	Povidone-Iodine			OFFSIDES
108	Prednisolone			SIDER
109	Prednisone acetate			OFFSIDES
110	Prednisone		7196210	CTD
111	Ramipril			OFFSIDES
112	Rifabutin			OFFSIDES
113	Stavudine			OFFSIDES
114	Sufentanil			OFFSIDES
115	Tamoxifen			OFFSIDES
116	Tetracycline			OFFSIDES
117	Timolol			OFFSIDES
118	Tremorine			OFFSIDES
119	Trimetazidine			OFFSIDES
120	Ubiquinone			OFFSIDES
121	candesartan cilexetil			OFFSIDES
122	difluprednate			SIDER
123	dorzolamide			SIDER
124	etravirine			OFFSIDES
125	fludarabine			OFFSIDES
126	gemcitabine			OFFSIDES
127	limaprost			OFFSIDES
128	malvidin			SIDER
129	medrysone			SIDER
130	pegaptanib			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Iritis	60.2%
2	Exfoliation Syndrome	38.8%
3	Iridocorneal endothelial syndrome	38.5%
4	Choroid Diseases	35.2%
5	Choroiditis	34.1%
6	Uveitis, Posterior	34.1%
7	Pars Planitis	32.9%
8	Uveal Neoplasms	28.5%
9	Aniridia	27.2%
10	Chorioretinitis	24.6%
11	Asthenopia	21.6%
12	Conjunctival Diseases	21.6%
13	Corneal Diseases	21.6%
14	Eyelid Diseases	21.6%
15	Lacrimal Apparatus Diseases	21.6%
16	Lens Diseases	21.6%
17	Ocular Hypertension	21.6%
18	Ocular Hypotension	21.6%
19	Retinal Diseases	21.6%
20	Scleral Diseases	21.6%
21	Vitreous Detachment	21.6%
22	Posterior Vitreous Detachment	21.6%
23	Uveitis	20.1%
24	Choroid Hemorrhage	19.9%
25	Uveomeningoencephalitic Syndrome	19.7%
26	Retinal Degeneration	17.9%
27	Eye Abnormalities	16.3%
28	Eye Infection	16.3%
29	Eye Manifestations	16.3%
30	Eye Neoplasms	16.3%
31	Optic Neuropathy	16.3%
32	Choroidal Neovascularization	15.9%
33	Behcet Syndrome	15.9%
34	Retinal Dysplasia	15.3%
35	Iris Diseases	15.1%
36	Blepharophimosis	14.2%
37	Xerophthalmia	14.2%
38	Low Tension Glaucoma	14.2%
39	Eyelid Neoplasms	14.1%
40	Retinal Hemorrhage	14.1%
41	Panuveitis	13.1%
42	Ocular Motility Disorders	13.1%
43	Cyclophoria	13.1%
44	Pupil Disorders	12.9%
45	Eye Hemorrhage	12.7%
46	Vision Disorders	12.6%
47	Metamorphopsia	12.6%
48	Visual Impairment	12.6%
49	Eye Injuries	12.5%
50	Iridocyclitis	12.2%
51	Duane Retraction Syndrome	11.8%
52	Angioid Streaks	11.7%
53	Anisometropia	11.7%
54	Aphakia	11.7%
55	Astigmatism	11.7%
56	Blepharitis	11.7%
57	Blepharoptosis	11.7%
58	Blepharospasm	11.7%
59	Conjunctivitis	11.7%
60	Corneal edema	11.7%
61	Corneal Opacity	11.7%
62	Dacryocystitis	11.7%
63	Dry Eye Syndromes	11.7%
64	Ectropion	11.7%
65	Enophthalmos	11.7%
66	Entropion	11.7%
67	Episcleritis	11.7%
68	Exophthalmos	11.7%
69	Glaucoma	11.7%
70	Keratitis	11.7%
71	Keratoconus	11.7%
72	Lacrimal Duct Obstruction	11.7%
73	Lens dislocation	11.7%
74	Lens Subluxation	11.7%
75	Mydriasis	11.7%
76	Myopia	11.7%
77	Presbyopia	11.7%
78	Pterygium	11.7%
79	Retinal Detachment	11.7%
80	Retinitis	11.7%
81	Scleritis	11.7%
82	Corneal Neovascularization	11.7%
83	Orbital Pseudotumor	11.7%
84	Cataract	11.7%
85	Pinguecula	11.7%
86	Trichiasis	11.7%
87	Corneal Scar	11.6%
88	Corneal Ulcer	11.4%
89	Keratoconjunctivitis	10.7%
90	Panophthalmitis	10.2%
91	Keratoconjunctivitis Sicca	10.1%
92	Retinitis Pigmentosa	10%
93	Pigmentary retinopathy	10%
94	Anterior uveitis	9.7%
95	Hordeolum	9.4%
96	Color blindness	9.3%
97	Anophthalmos	8.8%
98	Endophthalmitis	8.8%
99	Microphthalmos	8.8%
100	Optic Atrophy	8.8%
101	Optic Neuritis	8.8%
102	Papilledema	8.8%
103	Pemphigoid, Benign Mucous Membrane	8.8%
104	Retinal Artery Occlusion	8.8%
105	Retinopathy of Prematurity	8.8%
106	Strabismus	8.8%
107	Tolosa-Hunt Syndrome	8.8%
108	Orbital Cellulitis	8.8%
109	Retinal Vasculitis	8.8%
110	Hypertensive Retinopathy	8.8%
111	Retrobulbar Hemorrhage	8.8%
112	Corneal Endothelial Cell Loss	8.8%
113	Hyphema	8.7%
114	Retinal Neovascularization	8.7%
115	Vitreous Hemorrhage	8.7%
116	Retinoblastoma	8.6%
117	Trachoma	7.9%
118	Acanthamoeba Keratitis	7.2%
119	Keratitis, Herpetic	7.2%
120	Cytomegalovirus Retinitis	7.2%
121	Bacterial conjunctivitis	7.1%
122	Optic Neuropathy, Ischemic	7.1%
123	Anterior Ischemic Optic Neuropathy	7.1%
124	Angle Closure Glaucoma	7.1%
125	Glaucoma, Open-Angle	7.1%
126	Macular degeneration	7.1%
127	Retinal Drusen	7.1%
128	Retinal Necrosis Syndrome, Acute	7.1%
129	Retinoschisis	7.1%
130	Retinal Vein Occlusion	7%
131	Corneal Perforation	7%
132	Anisocoria	7%
133	Diabetic Retinopathy	7%
134	Tonic Pupil	7%
135	Eye pain	7%
136	Orbital Myositis	7%
137	Diplopia	6.9%
138	Scotoma	6.9%
139	Photophobia	6.9%
140	Amaurosis	6.9%
141	Blindness	6.9%
142	Ophthalmoplegia	5.8%
143	External Ophthalmoplegia	5.8%
144	Amblyopia	5.8%
145	Esotropia	5.3%
146	Exotropia	5.3%
147	Aicardi's syndrome	4.4%
148	CHARGE Syndrome	4.3%
149	Congenital nystagmus	4.3%
150	Herpes Zoster Ophthalmicus	4.3%
151	Hemianopsia	4.2%
152	Amaurosis Fugax	4.2%
153	Blindness, Cortical	4.2%
154	Optic Atrophy, Hereditary, Leber	4%
155	Opsoclonus-Myoclonus Syndrome	3.9%
156	Albinism	3.9%
157	Ophthalmia Neonatorum	3.7%
158	Graves Disease	3.6%
159	Horner Syndrome	3.6%
160	Mandibulofacial Dysostosis	3.5%
161	Miller Fisher Syndrome	3.4%
162	Sicca Syndrome	2.7%
163	Sjogren's Syndrome	2.7%
164	Ophthalmoplegic Migraine	2.4%
165	Progressive supranuclear palsy	2.4%
166	Kearns-Sayre syndrome	2.1%
167	Neuromyelitis Optica	2.1%
168	Alstrom Syndrome	1.9%
169	Optic Nerve Glioma	1.7%

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