MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Retinoschisis

(UMLS:C0152439)

Definition:: A vitreoretinal dystrophy characterized by splitting of the neuroretinal layers. It occurs in two forms: degenerative retinoschisis and X chromosome-linked juvenile retinoschisis.
UMLS ID:: C0152439
MeSH ID:: D041441

Classification:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.768.585.865

Synonym(s)

Retinoschisis

RS - Retinoschisis

Retinoschisis, NOS

Retinoschisis, unspecified

Schisis of retina

retinoschises

retinoschisis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Estradiol	FAERS: 3	US FAERS
2	Fluocinolone Acetonide	FAERS: 2	OFFSIDES US FAERS
3	Sertraline	FAERS: 2	US FAERS
4	apixaban	FAERS: 2	US FAERS
5	cefuroxime axetil	FAERS: 2	US FAERS
6	Albuterol	FAERS: 1	US FAERS
7	Dimethyl Fumarate	FAERS: 1	US FAERS
8	Latanoprost	FAERS: 1	US FAERS
9	Paclitaxel	FAERS: 1	US FAERS
10	Paroxetine	FAERS: 1	US FAERS
11	Pregabalin	FAERS: 1	US FAERS
12	Sildenafil Citrate	FAERS: 1	US FAERS
13	Tiotropium Bromide	FAERS: 1	US FAERS
14	cabozantinib	FAERS: 1	US FAERS
15	fluticasone furoate	FAERS: 1	US FAERS
16	trametinib	FAERS: 1	US FAERS
17	Anastrozole		OFFSIDES
18	Letrozole		OFFSIDES
19	Tamoxifen		OFFSIDES
20	brinzolamide		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Macular degeneration	46.7%
2	Retinal Drusen	46.7%
3	Angioid Streaks	31%
4	Retinal Detachment	31%
5	Retinitis	31%
6	Retinitis Pigmentosa	22.7%
7	Pigmentary retinopathy	22.7%
8	Retinal Hemorrhage	20.5%
9	Retinal Artery Occlusion	20.5%
10	Retinopathy of Prematurity	20.5%
11	Retinal Vasculitis	20.5%
12	Hypertensive Retinopathy	20.5%
13	Retinal Neovascularization	20.2%
14	Retinal Necrosis Syndrome, Acute	20%
15	Asthenopia	18.5%
16	Conjunctival Diseases	18.5%
17	Corneal Diseases	18.5%
18	Eyelid Diseases	18.5%
19	Lacrimal Apparatus Diseases	18.5%
20	Lens Diseases	18.5%
21	Ocular Hypertension	18.5%
22	Ocular Hypotension	18.5%
23	Scleral Diseases	18.5%
24	Vitreous Detachment	18.5%
25	Posterior Vitreous Detachment	18.5%
26	Retinal Dysplasia	17.2%
27	Retinal Vein Occlusion	15.3%
28	Diabetic Retinopathy	15.1%
29	Chorioretinitis	14.1%
30	Eye Abnormalities	12.2%
31	Eye Infection	12.2%
32	Eye Manifestations	12.2%
33	Eye Neoplasms	12.2%
34	Optic Neuropathy	12.2%
35	Xerophthalmia	11.4%
36	Low Tension Glaucoma	11.4%
37	Iridocorneal endothelial syndrome	11.4%
38	Cytomegalovirus Retinitis	10.7%
39	Anisometropia	10.3%
40	Aphakia	10.3%
41	Astigmatism	10.3%
42	Blepharitis	10.3%
43	Blepharophimosis	10.3%
44	Blepharoptosis	10.3%
45	Blepharospasm	10.3%
46	Choroid Diseases	10.3%
47	Conjunctivitis	10.3%
48	Corneal edema	10.3%
49	Corneal Opacity	10.3%
50	Dacryocystitis	10.3%
51	Dry Eye Syndromes	10.3%
52	Ectropion	10.3%
53	Enophthalmos	10.3%
54	Entropion	10.3%
55	Episcleritis	10.3%
56	Exophthalmos	10.3%
57	Glaucoma	10.3%
58	Iris Diseases	10.3%
59	Keratitis	10.3%
60	Keratoconus	10.3%
61	Lacrimal Duct Obstruction	10.3%
62	Lens dislocation	10.3%
63	Lens Subluxation	10.3%
64	Mydriasis	10.3%
65	Myopia	10.3%
66	Presbyopia	10.3%
67	Pterygium	10.3%
68	Scleritis	10.3%
69	Uveal Neoplasms	10.3%
70	Uveitis	10.3%
71	Corneal Neovascularization	10.3%
72	Orbital Pseudotumor	10.3%
73	Cataract	10.3%
74	Pinguecula	10.3%
75	Trichiasis	10.3%
76	Eyelid Neoplasms	10.3%
77	Aniridia	9.1%
78	Ocular Motility Disorders	9.1%
79	Cyclophoria	9.1%
80	Retinoblastoma	9.1%
81	Pupil Disorders	8.9%
82	Keratoconjunctivitis	8.9%
83	Eye Hemorrhage	8.8%
84	Vision Disorders	8.7%
85	Metamorphopsia	8.7%
86	Visual Impairment	8.7%
87	Eye Injuries	8.6%
88	Corneal Ulcer	8.5%
89	Choroid Hemorrhage	8.4%
90	Duane Retraction Syndrome	8.2%
91	Keratoconjunctivitis Sicca	8.2%
92	Corneal Scar	8.1%
93	Choroiditis	7.1%
94	Iridocyclitis	7.1%
95	Iritis	7.1%
96	Retinal Degeneration	7%
97	Anophthalmos	6.8%
98	Endophthalmitis	6.8%
99	Microphthalmos	6.8%
100	Optic Atrophy	6.8%
101	Optic Neuritis	6.8%
102	Papilledema	6.8%
103	Pemphigoid, Benign Mucous Membrane	6.8%
104	Strabismus	6.8%
105	Tolosa-Hunt Syndrome	6.8%
106	Orbital Cellulitis	6.8%
107	Retrobulbar Hemorrhage	6.8%
108	Corneal Endothelial Cell Loss	6.8%
109	Hyphema	6.7%
110	Vitreous Hemorrhage	6.7%
111	Hordeolum	6.7%
112	Angle Closure Glaucoma	6.7%
113	Glaucoma, Open-Angle	6.7%
114	Panuveitis	6.7%
115	Pars Planitis	6.7%
116	Exfoliation Syndrome	6.7%
117	Color blindness	6.6%
118	Kearns-Sayre syndrome	6%
119	Trachoma	5.6%
120	Acanthamoeba Keratitis	5.4%
121	Keratitis, Herpetic	5.4%
122	Bacterial conjunctivitis	5.3%
123	Corneal Perforation	5.2%
124	Optic Neuropathy, Ischemic	5.2%
125	Anterior Ischemic Optic Neuropathy	5.2%
126	Anisocoria	5%
127	Tonic Pupil	5%
128	Eye pain	5%
129	Orbital Myositis	5%
130	Diplopia	5%
131	Scotoma	5%
132	Photophobia	5%
133	Amaurosis	5%
134	Blindness	5%
135	Anterior uveitis	4.9%
136	Uveitis, Posterior	4.9%
137	Esotropia	4.4%
138	Exotropia	4.4%
139	Choroidal Neovascularization	4.4%
140	Ophthalmoplegia	4%
141	External Ophthalmoplegia	4%
142	Amblyopia	4%
143	Panophthalmitis	3.6%
144	Uveomeningoencephalitic Syndrome	3.4%
145	CHARGE Syndrome	3.4%
146	Congenital nystagmus	3.4%
147	Herpes Zoster Ophthalmicus	3.3%
148	Hemianopsia	3.3%
149	Amaurosis Fugax	3.2%
150	Blindness, Cortical	3.2%
151	Aicardi's syndrome	2.9%
152	Optic Atrophy, Hereditary, Leber	2.9%
153	Ophthalmia Neonatorum	2.8%
154	Graves Disease	2.7%
155	Horner Syndrome	2.7%
156	Mandibulofacial Dysostosis	2.6%
157	Opsoclonus-Myoclonus Syndrome	2.5%
158	Albinism	2.5%
159	Miller Fisher Syndrome	2.2%
160	Sicca Syndrome	1.9%
161	Sjogren's Syndrome	1.9%
162	Ophthalmoplegic Migraine	1.7%
163	Progressive supranuclear palsy	1.6%
164	Neuromyelitis Optica	1.5%
165	Alstrom Syndrome	1.3%
166	Behcet Syndrome	1.2%
167	Optic Nerve Glioma	1.2%

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