MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Trachoma

(UMLS:C0040592)

Definition:: A chronic infection of the CONJUNCTIVA and CORNEA caused by CHLAMYDIA TRACHOMATIS.
UMLS ID:: C0040592
MeSH ID:: D014141

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.354.225.800|C01.252.400.210.210.800|C01.539.375.354.220.800

Classification 2:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.187.183.220.889|C11.204.813|C11.294.354.220.800

Synonym(s)

Trachoma

Trachoma, NOS

Trachoma, unspecified

trachoma

trachomatis; Chlamydia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Desogestrel	FAERS: 1		US FAERS
2	Sildenafil Citrate	FAERS: 1		US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Ophthalmia Neonatorum	42.4%
2	Hordeolum	34.7%
3	Corneal Ulcer	27.6%
4	Panophthalmitis	23.6%
5	Keratoconjunctivitis	22.1%
6	Endophthalmitis	21.1%
7	Borrelia Infections	19.7%
8	Leptospirosis	19.7%
9	Iridocorneal endothelial syndrome	19%
10	Keratoconjunctivitis Sicca	18.8%
11	Central Nervous System Bacterial Infections	17.4%
12	Lyme Disease	17.3%
13	Relapsing Fever	17.3%
14	Corneal Scar	17.2%
15	Skin Diseases, Bacterial	16.9%
16	Bacteremia	16.8%
17	Xerophthalmia	16.5%
18	Retinal Dysplasia	16.5%
19	Corneal edema	16%
20	Corneal Opacity	16%
21	Keratitis	16%
22	Keratoconus	16%
23	Corneal Neovascularization	16%
24	Lymphogranuloma Venereum	15.8%
25	Gram-Positive Bacterial Infections	15.6%
26	Lyme Neuroborreliosis	15.5%
27	Syphilis	15.4%
28	Bacterial Endocarditis	15.3%
29	Erythema Chronicum Migrans	15.1%
30	Retinal Degeneration	15%
31	Human Ehrlichiosis	14.6%
32	Aniridia	14.5%
33	Asthenopia	14.4%
34	Eyelid Diseases	14.4%
35	Lacrimal Apparatus Diseases	14.4%
36	Lens Diseases	14.4%
37	Ocular Hypertension	14.4%
38	Ocular Hypotension	14.4%
39	Retinal Diseases	14.4%
40	Scleral Diseases	14.4%
41	Vitreous Detachment	14.4%
42	Posterior Vitreous Detachment	14.4%
43	Corneal Endothelial Cell Loss	14%
44	Acanthamoeba Keratitis	13.9%
45	Keratitis, Herpetic	13.9%
46	Bacterial Vaginosis	13.6%
47	Bordetella Infections	13.6%
48	Brucellosis	13.6%
49	Campylobacter infection	13.6%
50	Enterobacteriaceae Infections	13.6%
51	Pseudomonas Infections	13.6%
52	Q Fever	13.6%
53	Vibrio Infections	13.6%
54	Helicobacter Infections	13.6%
55	Neisseriaceae Infections	13.6%
56	Burkholderia Infections	13.6%
57	Flavobacteriaceae Infections	13.6%
58	Moraxellaceae Infections	13.6%
59	Burkholderia cepacia Infection	13.6%
60	Blepharophimosis	13.3%
61	Uveal Neoplasms	13.3%
62	Human anaplasmosis	13.3%
63	Gonorrhea	13.3%
64	Eyelid Neoplasms	13.3%
65	Retinal Hemorrhage	13.3%
66	Pterygium	13.2%
67	Pinguecula	13.2%
68	Neurosyphilis	13%
69	Eye Infection	12.9%
70	Ulcerative stomatitis	12.9%
71	Mycetoma	12.9%
72	Eye Abnormalities	12.7%
73	Eye Manifestations	12.7%
74	Eye Neoplasms	12.7%
75	Optic Neuropathy	12.7%
76	Erysipelas	12.7%
77	Staphylococcal Skin Infections	12.7%
78	Mycoses	12.5%
79	Low Tension Glaucoma	12.4%
80	Japanese Spotted Fever	12.4%
81	Pneumonia, Bacterial	12.1%
82	Duane Retraction Syndrome	12%
83	Hidradenitis Suppurativa	11.9%
84	Corneal Perforation	11.7%
85	Ecthyma	11.6%
86	Subacute Bacterial Endocarditis	11.6%
87	Pemphigoid, Benign Mucous Membrane	11.6%
88	Erythrasma	11.5%
89	Ocular Motility Disorders	11.4%
90	Cyclophoria	11.4%
91	Pertussis	11.4%
92	Pupil Disorders	11.3%
93	Eye Hemorrhage	11.2%
94	Impetigo	11.2%
95	Vision Disorders	11.2%
96	Metamorphopsia	11.2%
97	Visual Impairment	11.2%
98	Eye Injuries	11.1%
99	Central Nervous System Infection	11%
100	Choroid Hemorrhage	11%
101	Pelvic Infection	10.8%
102	Wound Infection	10.8%
103	Soft Tissue Infection	10.8%
104	Community-Acquired Infections	10.8%
105	Retinoblastoma	10.6%
106	Bacterial conjunctivitis	10.3%
107	Trachoma	10.3%
108	Chlamydia Infections	10.2%
109	Conjunctival Diseases	10.1%
110	Rhinoscleroma	10.1%
111	Chorioretinitis	10%
112	Dermatomycoses	9.9%
113	Cytomegalovirus Retinitis	9.9%
114	Retinitis Pigmentosa	9.9%
115	Pigmentary retinopathy	9.9%
116	Color blindness	9.9%
117	Respiratory Tract Infections	9.7%
118	Bone Diseases, Infectious	9.6%
119	Pregnancy Complications, Infectious	9.6%
120	Skin Diseases, Infectious	9.6%
121	Psittacosis	9.5%
122	Arthritis, Infectious	9.5%
123	Suppuration	9.5%
124	Cross Infection	9.5%
125	Septicemia	9.5%
126	Sepsis	9.5%
127	Gram-Negative Bacterial Infections	9.2%
128	Rocky Mountain Spotted Fever	9%
129	Pars Planitis	8.9%
130	Actinomycetales Infections	8.9%
131	Clostridium Infections	8.9%
132	Listeriosis	8.9%
133	Staphylococcal Infections	8.9%
134	Streptococcal Infections	8.9%
135	Bacillaceae Infections	8.9%
136	Clostridium difficile infection	8.9%
137	Opportunistic Infections	8.8%
138	Corneal Diseases	8.7%
139	Cellulitis	8.6%
140	Urinary tract infection	8.5%
141	Angioid Streaks	8.5%
142	Anisometropia	8.5%
143	Aphakia	8.5%
144	Astigmatism	8.5%
145	Blepharitis	8.5%
146	Blepharoptosis	8.5%
147	Blepharospasm	8.5%
148	Choroid Diseases	8.5%
149	Dacryocystitis	8.5%
150	Dry Eye Syndromes	8.5%
151	Ectropion	8.5%
152	Enophthalmos	8.5%
153	Entropion	8.5%
154	Episcleritis	8.5%
155	Exophthalmos	8.5%
156	Glaucoma	8.5%
157	Iris Diseases	8.5%
158	Lacrimal Duct Obstruction	8.5%
159	Lens dislocation	8.5%
160	Lens Subluxation	8.5%
161	Mydriasis	8.5%
162	Myopia	8.5%
163	Presbyopia	8.5%
164	Retinal Detachment	8.5%
165	Retinitis	8.5%
166	Scleritis	8.5%
167	Uveitis	8.5%
168	Orbital Pseudotumor	8.5%
169	Cataract	8.5%
170	Trichiasis	8.5%
171	Infection	8.4%
172	Staphylococcal Scalded Skin Syndrome	8.4%
173	Acinetobacter Infections	8.4%
174	Bacteroides Infections	8.4%
175	Cholera	8.4%
176	Escherichia coli Infections	8.4%
177	Haemophilus Infections	8.4%
178	Klebsiella Infections	8.4%
179	Meningococcal Infections	8.4%
180	Mycoplasma Infections	8.4%
181	Pasteurella Infections	8.4%
182	Proteus Infections	8.4%
183	Rickettsia Infections	8.4%
184	Salmonella infections	8.4%
185	Scrub Typhus	8.4%
186	Serratia Infections	8.4%
187	Ureaplasma Infections	8.4%
188	Erysipelothrix infection	8%
189	Choroiditis	7.9%
190	Iridocyclitis	7.9%
191	Iritis	7.9%
192	Meningitis, Haemophilus	7.9%
193	Candidiasis, Chronic Mucocutaneous	7.8%
194	Cutaneous Candidiasis	7.8%
195	Sexually Transmitted Diseases	7.8%
196	Meningitis, Listeria	7.8%
197	Furunculosis	7.7%
198	furuncle	7.7%
199	Syphilis, Congenital	7.6%
200	Fungemia	7.6%
201	Endotoxemia	7.6%
202	Anophthalmos	7.4%
203	Microphthalmos	7.4%
204	Optic Atrophy	7.4%
205	Optic Neuritis	7.4%
206	Papilledema	7.4%
207	Retinal Artery Occlusion	7.4%
208	Retinopathy of Prematurity	7.4%
209	Strabismus	7.4%
210	Tolosa-Hunt Syndrome	7.4%
211	Orbital Cellulitis	7.4%
212	Retinal Vasculitis	7.4%
213	Hypertensive Retinopathy	7.4%
214	Retrobulbar Hemorrhage	7.4%
215	Hyphema	7.4%
216	Retinal Neovascularization	7.4%
217	Vitreous Hemorrhage	7.4%
218	Brain Abscess	7.3%
219	Joint Tuberculosis	7.2%
220	Tuberculosis, Osteoarticular	7.2%
221	Bone Tuberculosis	7.2%
222	Meningitis, Bacterial	6.9%
223	Candidemia	6.8%
224	Optic Neuropathy, Ischemic	6.7%
225	Anterior Ischemic Optic Neuropathy	6.7%
226	Meningitis, Pneumococcal	6.6%
227	Retinal Vein Occlusion	6.6%
228	Aspergillosis	6.6%
229	Candidiasis	6.6%
230	Coccidioidomycosis	6.6%
231	Histoplasmosis	6.6%
232	Paracoccidioidomycosis	6.6%
233	Zygomycosis	6.6%
234	Phaeohyphomycosis	6.6%
235	Pneumocystis Infections	6.6%
236	Anisocoria	6.6%
237	Diabetic Retinopathy	6.6%
238	Tonic Pupil	6.6%
239	Eye pain	6.6%
240	Orbital Myositis	6.6%
241	Herpes Zoster Ophthalmicus	6.6%
242	Blastomycosis	6.6%
243	Diplopia	6.6%
244	Scotoma	6.6%
245	Photophobia	6.6%
246	Amaurosis	6.6%
247	Blindness	6.6%
248	Dysentery, Bacillary	6.5%
249	carbuncle	6.3%
250	Conjunctivitis	6.1%
251	Ophthalmoplegia	5.9%
252	External Ophthalmoplegia	5.9%
253	Amblyopia	5.9%
254	Erythema Induratum	5.8%
255	Otomycosis	5.8%
256	Neuroaspergillosis	5.8%
257	Paratyphoid Fever	5.8%
258	Plague	5.8%
259	Typhoid Fever	5.8%
260	TYPHUS	5.8%
261	Yersinia pseudotuberculosis Infections	5.8%
262	Bubonic Plague	5.8%
263	Chromoblastomycosis	5.8%
264	Dermatophytosis	5.8%
265	Sporotrichosis	5.8%
266	Tinea	5.8%
267	Tinea Versicolor	5.8%
268	Trichophytosis	5.8%
269	Hyalohyphomycosis	5.8%
270	Piedra	5.8%
271	Central Nervous System Fungal Infections	5.8%
272	Angle Closure Glaucoma	5.6%
273	Glaucoma, Open-Angle	5.6%
274	Macular degeneration	5.6%
275	Panuveitis	5.6%
276	Retinal Drusen	5.6%
277	Retinal Necrosis Syndrome, Acute	5.6%
278	Retinoschisis	5.6%
279	Exfoliation Syndrome	5.6%
280	Actinomycosis	5.6%
281	Corynebacterium Infections	5.6%
282	Gas Gangrene	5.6%
283	Mycobacterium Infections	5.6%
284	Nocardia Infections	5.6%
285	Pneumococcal Infections	5.6%
286	Scarlet Fever	5.6%
287	Tetanus	5.6%
288	Pulmonary Nocardiosis	5.6%
289	Peritonitis	5.4%
290	Osteomyelitis	5.3%
291	Periostitis	5.3%
292	Surgical Wound Infection	5.3%
293	Abscess	5.3%
294	Adnexitis	5.3%
295	Empyema	5.3%
296	Pelvic Inflammatory Disease	5.3%
297	Optic Atrophy, Hereditary, Leber	5.3%
298	Tuberculosis, Meningeal	5.2%
299	Lung Diseases, Fungal	5.2%
300	Salmonella Infections, Animal	5.2%
301	Salmonella food poisoning	5.1%
302	Aicardi's syndrome	5%
303	Esotropia	4.9%
304	Exotropia	4.9%
305	Choroidal Neovascularization	4.9%
306	Superinfection	4.8%
307	Puerperal Infection	4.7%
308	Spondylitis	4.7%
309	Appendicitis	4.7%
310	Bacteriuria	4.7%
311	Pyuria	4.7%
312	Pyomyositis	4.7%
313	Invasive Pulmonary Aspergillosis	4.7%
314	Endotoxic shock	4.7%
315	Septic Shock	4.7%
316	Toxic Shock Syndrome	4.7%
317	Opsoclonus-Myoclonus Syndrome	4.6%
318	Albinism	4.6%
319	Tuberculosis, Spinal	4.5%
320	Uveomeningoencephalitic Syndrome	4.4%
321	CHARGE Syndrome	4.4%
322	Rheumatic Fever	4.4%
323	Congenital nystagmus	4.4%
324	Hemianopsia	4.3%
325	Enterocolitis, Pseudomembranous	4.3%
326	pseudomembranous colitis	4.3%
327	Amaurosis Fugax	4.3%
328	Blindness, Cortical	4.3%
329	Meningitis, Cryptococcal	4.2%
330	Arthritis, Reactive	4.2%
331	Miller Fisher Syndrome	4.2%
332	Anterior uveitis	4.2%
333	Uveitis, Posterior	4.2%
334	Bacterial Infections	4.1%
335	Graves Disease	4%
336	Botulism	4%
337	Diphtheria	3.9%
338	Leprosy	3.9%
339	Mycobacterium Infections, Nontuberculous	3.9%
340	Tuberculosis	3.9%
341	Mycobacterium abscessus Infection	3.9%
342	Horner Syndrome	3.9%
343	Waterhouse-Friderichsen Syndrome	3.9%
344	AIDS-Related Opportunistic Infections	3.9%
345	Mandibulofacial Dysostosis	3.9%
346	Fusariosis	3.8%
347	Mucormycosis	3.7%
348	Psoas Abscess	3.7%
349	Abdominal Abscess	3.7%
350	Rheumatic Heart Disease	3.5%
351	Lemierre Syndrome	3.4%
352	Tinea Capitis	3.4%
353	Onychomycosis	3.4%
354	Toxoplasmosis, Cerebral	3.4%
355	Kearns-Sayre syndrome	3.3%
356	Oral candidiasis	3.3%
357	Pulmonary Aspergillosis	3.3%
358	Bronchopulmonary Aspergillosis	3.3%
359	Sicca Syndrome	3.3%
360	Sjogren's Syndrome	3.3%
361	Diverticulitis	3.3%
362	Mycobacterium avium-intracellulare Infection	3.1%
363	Lymph Node Tuberculosis	3.1%
364	Tuberculosis, Miliary	3.1%
365	Tuberculosis, Multidrug-Resistant	3.1%
366	Leprosy, Multibacillary	3.1%
367	Latent Tuberculosis	3.1%
368	Tinea Pedis	3.1%
369	Ophthalmoplegic Migraine	3%
370	Progressive supranuclear palsy	3%
371	Lung Abscess	3%
372	Diverticulum	2.9%
373	Diverticulosis	2.9%
374	Meningitis, Fungal	2.9%
375	Discitis	2.9%
376	Mastoiditis	2.9%
377	Petrositis	2.9%
378	Candidiasis, Vulvovaginal	2.9%
379	Neuromyelitis Optica	2.8%
380	Tuberculosis, Gastrointestinal	2.8%
381	Tuberculosis, Central Nervous System	2.7%
382	Borderline leprosy	2.7%
383	Leprosy, Lepromatous	2.7%
384	Tuberculoid leprosy	2.7%
385	Extensively Drug-Resistant Tuberculosis	2.7%
386	Retropharyngeal Abscess	2.6%
387	Epidural Abscess	2.6%
388	Alstrom Syndrome	2.6%
389	Peritonsillar Abscess	2.6%
390	Tuberculosis, Pulmonary	2.5%
391	Optic Nerve Glioma	2.4%
392	Liver Abscess	2.3%
393	Behcet Syndrome	2.1%
394	Tuberculosis, Renal	1.8%
395	Aspergillosis, Allergic Bronchopulmonary	1.5%
396	Liver Abscess, Amebic	1.3%

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