MetaADEDB 2.0 @ LMMD
Exophthalmos
(UMLS:C0015300)
Definition:
Abnormal protrusion of both eyes; may be caused by endocrine gland malfunction, malignancy, injury, or paralysis of the extrinsic muscles of the eye.
UMLS ID:
C0015300
MeSH ID:
D005094
Classification:
Name:
Eye Diseases
MeSH Tree Number(s):
C11.675.349
Synonym(s)
1.
Exophthalmos
2.
Anterior bulging of the globe
3.
Anterior bulging of the globe of eye
4.
Bulging eye
5.
EXOPHTHALMOS
6.
Exophthalmia
7.
Exophthalmos, NOS
8.
Exophthalmos, unspecified
9.
Eye bulging
10.
Eye displaced forwards
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1ThyroxineFAERS: 40US FAERS
2Zoledronic AcidFAERS: 28
Canada Vigilance: 1		Canada Vigilance
US FAERS
3LenalidomideFAERS: 8US FAERS
4ThyroxineFAERS: 8US FAERS
5Dimethyl FumarateFAERS: 7US FAERS
6Duloxetine HydrochlorideFAERS: 7
Canada Vigilance: 1		Canada Vigilance
US FAERS
7MethimazoleFAERS: 7OFFSIDES
US FAERS
8Fingolimod HydrochlorideFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
9LevofloxacinFAERS: 6US FAERS
10TadalafilFAERS: 6US FAERS
11BimatoprostFAERS: 5US FAERS
12Glatiramer AcetateFAERS: 5US FAERS
13IbuprofenFAERS: 56409656CTD
US FAERS
14Imatinib MesylateFAERS: 5US FAERS
15RisperidoneFAERS: 5US FAERS
16LorazepamFAERS: 4US FAERS
17MethotrexateFAERS: 4US FAERS
18PrednisoneFAERS: 4SIDER
US FAERS
19Sildenafil CitrateFAERS: 4US FAERS
20carbidopa, levodopa drug combinationFAERS: 4US FAERS
21teriflunomideFAERS: 4US FAERS
22MDV 3100FAERS: 3US FAERS
23Methylprednisolone HemisuccinateFAERS: 3US FAERS
24MinocyclineFAERS: 3US FAERS
25MoxifloxacinFAERS: 3US FAERS
26PrednisoloneFAERS: 3OFFSIDES
SIDER
US FAERS
27PregabalinFAERS: 3OFFSIDES
SIDER
US FAERS
28RosiglitazoneFAERS: 3US FAERS
29TemozolomideFAERS: 3US FAERS
30TopiramateFAERS: 3US FAERS
31VoriconazoleFAERS: 3US FAERS
32WarfarinFAERS: 3US FAERS
33WarfarinFAERS: 3US FAERS
34iopromideFAERS: 3US FAERS
35ioversolFAERS: 3OFFSIDES
US FAERS
36AlendronateFAERS: 2US FAERS
37AmiodaroneFAERS: 2US FAERS
38AmlodipineFAERS: 2US FAERS
39Amoxicillin-Potassium Clavulanate CombinationFAERS: 2US FAERS
40BaclofenFAERS: 2US FAERS
41CinacalcetFAERS: 2US FAERS
42Desvenlafaxine SuccinateFAERS: 2US FAERS
43DiphenhydramineFAERS: 2US FAERS
44DroxidopaFAERS: 2US FAERS
45EptifibatideFAERS: 2US FAERS
46LCZ 696FAERS: 2US FAERS
47Lisdexamfetamine DimesylateFAERS: 2US FAERS
48LosartanFAERS: 2US FAERS
49Methylprednisolone AcetateFAERS: 2US FAERS
50MethylprednisoloneFAERS: 2SIDER
US FAERS
51ParoxetineFAERS: 2US FAERS
52PropylthiouracilFAERS: 2OFFSIDES
US FAERS
53Quetiapine FumarateFAERS: 2US FAERS
54Risedronic AcidFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
55SertralineFAERS: 2US FAERS
56Sodium iodide I 131FAERS: 2US FAERS
57SorafenibFAERS: 2US FAERS
58TacrolimusFAERS: 2US FAERS
59Tiotropium BromideFAERS: 2US FAERS
60TravoprostFAERS: 2US FAERS
61Triamcinolone AcetonideFAERS: 2US FAERS
62Venlafaxine HydrochlorideFAERS: 2US FAERS
63dofetilideFAERS: 2OFFSIDES
US FAERS
64dorzolamideFAERS: 2US FAERS
65regorafenibFAERS: 2US FAERS
66rizatriptanFAERS: 2US FAERS
67sibutramineFAERS: 2US FAERS
684-[(1R)-2-[6-[2-[(2,6-Dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol;[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate;diphenyl-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanolFAERS: 1US FAERS
69AR-13324FAERS: 1US FAERS
70Adzenys XR-ODTFAERS: 1US FAERS
71AlbuterolFAERS: 1US FAERS
72AmikacinFAERS: 1US FAERS
73AmiodaroneFAERS: 1US FAERS
74Atomoxetine HydrochlorideFAERS: 1US FAERS
75AustedoFAERS: 1US FAERS
76AzathioprineFAERS: 1US FAERS
77AzithromycinFAERS: 1US FAERS
78BortezomibFAERS: 1SIDER
US FAERS
79BuprenorphineFAERS: 1US FAERS
80CH5424802FAERS: 1US FAERS
81Calcium CarbonateFAERS: 1US FAERS
82CapecitabineFAERS: 1US FAERS
83Carbidopa, levodopa, and entacaponeFAERS: 1US FAERS
84CetirizineFAERS: 1US FAERS
85CitalopramFAERS: 1US FAERS
86CitalopramFAERS: 1US FAERS
87ClopidogrelFAERS: 1US FAERS
88ClozapineFAERS: 1US FAERS
89DecitabineFAERS: 1US FAERS
90DeferoxamineFAERS: 1US FAERS
91DiazepamFAERS: 1US FAERS
92DichlorphenamideFAERS: 1US FAERS
93DiltiazemFAERS: 1US FAERS
94EpinephrineFAERS: 1US FAERS
95ErythromycinFAERS: 1US FAERS
96EstradiolFAERS: 1US FAERS
97EverolimusFAERS: 1US FAERS
98FenofibrateFAERS: 1US FAERS
99FluconazoleFAERS: 1US FAERS
100GabapentinFAERS: 1US FAERS
101GanfortFAERS: 1US FAERS
102HaloperidolFAERS: 1US FAERS
103HydralazineFAERS: 1SIDER
US FAERS
104Imatinib MesylateFAERS: 1US FAERS
105ImiquimodFAERS: 1US FAERS
106Insulin GlargineFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
107IohexolFAERS: 1US FAERS
108KetotifenFAERS: 1US FAERS
109LamotrigineFAERS: 1US FAERS
110LatanoprostFAERS: 1US FAERS
111LidodermFAERS: 1US FAERS
112LinezolidFAERS: 1US FAERS
113LopinavirFAERS: 1US FAERS
114LosartanFAERS: 1US FAERS
115Lurasidone HydrochlorideFAERS: 1US FAERS
116MelphalanFAERS: 1US FAERS
117MethotrexateFAERS: 1US FAERS
118MethylphenidateFAERS: 1US FAERS
119MethylphenidateFAERS: 1US FAERS
120MetoclopramideFAERS: 1US FAERS
121Mycophenolic AcidFAERS: 1US FAERS
122NafcillinFAERS: 1US FAERS
123NebivololFAERS: 1US FAERS
124NiacinFAERS: 17880795CTD
US FAERS
125NicotineFAERS: 1US FAERS
126NorgestrelFAERS: 1US FAERS
127NuvaRingFAERS: 1US FAERS
128OctreotideFAERS: 1US FAERS
129OmeprazoleFAERS: 1US FAERS
130OmeprazoleFAERS: 1US FAERS
131OxcarbazepineFAERS: 1US FAERS
132Paliperidone PalmitateFAERS: 1US FAERS
133ParoxetineFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
134PrimidoneFAERS: 1US FAERS
135QsymiaFAERS: 1US FAERS
136RestasisFAERS: 1US FAERS
137Risedronic AcidFAERS: 1US FAERS
138RivaroxabanFAERS: 1US FAERS
139RoflumilastFAERS: 1US FAERS
140SimbrinzaFAERS: 1US FAERS
141Sitagliptin PhosphateFAERS: 1US FAERS
142Sodium ChlorideFAERS: 1US FAERS
143TamsulosinFAERS: 1US FAERS
144TamsulosinFAERS: 1US FAERS
145TelmisartanFAERS: 1US FAERS
146TeriparatideFAERS: 1US FAERS
147TobramycinFAERS: 1OFFSIDES
US FAERS
148TramadolFAERS: 1US FAERS
149VareniclineFAERS: 1US FAERS
150VemurafenibFAERS: 1US FAERS
151apixabanFAERS: 1US FAERS
152cefuroxime axetilFAERS: 1OFFSIDES
US FAERS
153clindamycin phosphateFAERS: 1US FAERS
154dabrafenibFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
155dexamethasone 21-phosphateFAERS: 1US FAERS
156fexofenadineFAERS: 1US FAERS
157gadobutrolFAERS: 1US FAERS
158gemcitabineFAERS: 1US FAERS
159levocetirizineFAERS: 1US FAERS
160lifitegrastFAERS: 1US FAERS
161montelukastFAERS: 1US FAERS
162prednisolone acetateFAERS: 1US FAERS
163ribociclibFAERS: 1US FAERS
164rofecoxibFAERS: 1US FAERS
165tafluprostFAERS: 1US FAERS
166AG-01298624114799CTD
167Acetaminophen6409656CTD
168AcetazolamideOFFSIDES
169AlcoholsOFFSIDES
170AmantadineOFFSIDES
171AmrinoneOFFSIDES
172Bendamustine HydrochlorideOFFSIDES
173BenztropineOFFSIDES
174BetahistineOFFSIDES
175BethanecholOFFSIDES
176BupivacaineOFFSIDES
177CabergolineOFFSIDES
178Calcium CompoundsOFFSIDES
179CarbamazepineOFFSIDES
180CaspofunginOFFSIDES
181CefadroxilOFFSIDES
182CefepimeOFFSIDES
183ChloramphenicolOFFSIDES
184ClomipramineSIDER
185Clorazepate DipotassiumOFFSIDES
186ClotrimazoleOFFSIDES
187Cocaine19458577CTD
188CortisoneSIDER
189CytarabineOFFSIDES
190DexamethasoneSIDER
191EnalaprilatOFFSIDES
192EtoposideOFFSIDES
193FamciclovirOFFSIDES
194FludrocortisoneSIDER
195FluoxetineSIDER
196FlutamideOFFSIDES
197HhAntag691Canada Vigilance: 1Canada Vigilance
198HydrochlorothiazideOFFSIDES
199HydrocortisoneSIDER
200IfosfamideOFFSIDES
201ImipramineOFFSIDES
202KinetinSIDER
203LevobunololOFFSIDES
204LithiumSIDER
205MetoprololOFFSIDES
206Morphine6409656CTD
207NaproxenCanada Vigilance: 1Canada Vigilance
208NeomycinOFFSIDES
209NevirapineOFFSIDES
210NitrofurantoinOFFSIDES
211OctreotideOFFSIDES
212OxymorphoneOFFSIDES
213PamidronateOFFSIDES
214Papaverine19901231CTD
215Penicillin VOFFSIDES
216PhenytoinOFFSIDES
217Piperacillin, Tazobactam Drug CombinationOFFSIDES
218Povidone-IodineOFFSIDES
219Raloxifene HydrochlorideOFFSIDES
220SelegilineOFFSIDES
221SertralineSIDER
222SotalolOFFSIDES
223SulfamethoxazoleOFFSIDES
224Sulindac6409656CTD
225Tamoxifen8522365CTD
OFFSIDES
226TiagabineOFFSIDES
227TriamcinoloneSIDER
228UreaOFFSIDES
229ValacyclovirOFFSIDES
230Valproic Acid15208813CTD
OFFSIDES
231VancomycinOFFSIDES
232Venlafaxine HydrochlorideSIDER
233betamethasone-17,21-dipropionateOFFSIDES
234calcium acetateOFFSIDES
235chlorhexidine gluconateOFFSIDES
236efavirenzOFFSIDES
237gadodiamideOFFSIDES
238gadoversetamideOFFSIDES
239haloperidol decanoateOFFSIDES
240isosorbide-5-mononitrateOFFSIDES
241prednisolone phosphateOFFSIDES
242sibutramineOFFSIDES
Similar ADE(s)
NameSemantic Similarity
1Enophthalmos42.9%
2Orbital Pseudotumor42.9%
3Orbital Cellulitis27.9%
4Retrobulbar Hemorrhage27.9%
5Asthenopia23.1%
6Conjunctival Diseases23.1%
7Corneal Diseases23.1%
8Eyelid Diseases23.1%
9Lacrimal Apparatus Diseases23.1%
10Lens Diseases23.1%
11Ocular Hypertension23.1%
12Ocular Hypotension23.1%
13Retinal Diseases23.1%
14Scleral Diseases23.1%
15Vitreous Detachment23.1%
16Posterior Vitreous Detachment23.1%
17Orbital Myositis20.5%
18Retinal Degeneration19%
19Xerophthalmia16.3%
20Low Tension Glaucoma16.3%
21Iridocorneal endothelial syndrome16.3%
22Eye Abnormalities15%
23Eye Infection15%
24Eye Manifestations15%
25Eye Neoplasms15%
26Optic Neuropathy15%
27Angioid Streaks14.3%
28Anisometropia14.3%
29Aphakia14.3%
30Astigmatism14.3%
31Blepharitis14.3%
32Blepharoptosis14.3%
33Blepharospasm14.3%
34Choroid Diseases14.3%
35Conjunctivitis14.3%
36Corneal edema14.3%
37Corneal Opacity14.3%
38Dacryocystitis14.3%
39Dry Eye Syndromes14.3%
40Ectropion14.3%
41Entropion14.3%
42Episcleritis14.3%
43Glaucoma14.3%
44Iris Diseases14.3%
45Keratitis14.3%
46Keratoconus14.3%
47Lacrimal Duct Obstruction14.3%
48Lens dislocation14.3%
49Lens Subluxation14.3%
50Mydriasis14.3%
51Myopia14.3%
52Presbyopia14.3%
53Pterygium14.3%
54Retinal Detachment14.3%
55Retinitis14.3%
56Scleritis14.3%
57Uveitis14.3%
58Corneal Neovascularization14.3%
59Cataract14.3%
60Pinguecula14.3%
61Trichiasis14.3%
62Blepharophimosis14%
63Uveal Neoplasms14%
64Retinal Dysplasia14%
65Eyelid Neoplasms13.9%
66Retinal Hemorrhage13.9%
67Keratoconjunctivitis13.6%
68Keratoconjunctivitis Sicca13.3%
69Aniridia12.6%
70Chorioretinitis12.6%
71Corneal Ulcer12.1%
72Choroid Hemorrhage12%
73Choroiditis11.7%
74Iridocyclitis11.7%
75Iritis11.7%
76Pars Planitis11.7%
77Duane Retraction Syndrome11.1%
78Ocular Motility Disorders11.1%
79Retinitis Pigmentosa11.1%
80Cyclophoria11.1%
81Pigmentary retinopathy11.1%
82Pupil Disorders10.9%
83Corneal Scar10.9%
84Eye Hemorrhage10.7%
85Vision Disorders10.6%
86Metamorphopsia10.6%
87Visual Impairment10.6%
88Eye Injuries10.5%
89Angle Closure Glaucoma10.3%
90Glaucoma, Open-Angle10.3%
91Macular degeneration10.3%
92Panuveitis10.3%
93Retinal Drusen10.3%
94Retinal Necrosis Syndrome, Acute10.3%
95Retinoschisis10.3%
96Exfoliation Syndrome10.3%
97Hordeolum9.5%
98Color blindness9.4%
99Anophthalmos9.3%
100Endophthalmitis9.3%
101Microphthalmos9.3%
102Optic Atrophy9.3%
103Optic Neuritis9.3%
104Papilledema9.3%
105Pemphigoid, Benign Mucous Membrane9.3%
106Retinal Artery Occlusion9.3%
107Retinopathy of Prematurity9.3%
108Strabismus9.3%
109Tolosa-Hunt Syndrome9.3%
110Retinal Vasculitis9.3%
111Hypertensive Retinopathy9.3%
112Corneal Endothelial Cell Loss9.3%
113Hyphema9.2%
114Retinal Neovascularization9.2%
115Vitreous Hemorrhage9.2%
116Trachoma8.5%
117Anterior uveitis8.5%
118Uveitis, Posterior8.5%
119Retinoblastoma8.3%
120Acanthamoeba Keratitis8.2%
121Keratitis, Herpetic8.2%
122Cytomegalovirus Retinitis8.2%
123Bacterial conjunctivitis8.1%
124Corneal Perforation7.9%
125Optic Neuropathy, Ischemic7%
126Anterior Ischemic Optic Neuropathy7%
127Retinal Vein Occlusion6.9%
128Anisocoria6.8%
129Diabetic Retinopathy6.8%
130Tonic Pupil6.8%
131Eye pain6.8%
132Diplopia6.8%
133Scotoma6.8%
134Photophobia6.8%
135Amaurosis6.8%
136Blindness6.8%
137Esotropia6.7%
138Exotropia6.7%
139Choroidal Neovascularization6.7%
140Panophthalmitis6.1%
141Ophthalmoplegia5.4%
142External Ophthalmoplegia5.4%
143Amblyopia5.4%
144Uveomeningoencephalitic Syndrome5.2%
145CHARGE Syndrome5.2%
146Congenital nystagmus5.1%
147Herpes Zoster Ophthalmicus5.1%
148Hemianopsia5%
149Amaurosis Fugax4.9%
150Blindness, Cortical4.9%
151Ophthalmia Neonatorum4.7%
152Optic Atrophy, Hereditary, Leber4.5%
153Horner Syndrome4%
154Mandibulofacial Dysostosis3.9%
155Aicardi's syndrome3.9%
156Opsoclonus-Myoclonus Syndrome3.4%
157Albinism3.3%
158Miller Fisher Syndrome2.9%
159Sicca Syndrome2.8%
160Sjogren's Syndrome2.8%
161Kearns-Sayre syndrome2.8%
162Ophthalmoplegic Migraine2.5%
163Progressive supranuclear palsy2.5%
164Neuromyelitis Optica2.2%
165Behcet Syndrome2.2%
166Alstrom Syndrome2%
167Optic Nerve Glioma1.8%
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