MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Gingival Hypertrophy

(UMLS:C0017567)

Definition:: Abnormal enlargement or overgrowth of the gingivae brought about by enlargement of existing cells.
UMLS ID:: C0017567
MeSH ID:: D005886

Classification:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.465.714.258.428.260

Synonym(s)

Gingival Hypertrophy

Gingival enlargement

Gingival hypertrophy

Gingival hypertrophy, NOS

Gum enlargement

Gum hypertrophy

Hypertrophic gingivitis

Hypertrophy of gingiva

Hypertrophy of gingivae

10.

Hypertrophy of gums

11.

gingival hypertrophy

12.

gum; hypertrophy

13.

gum; hypertrophy mucous membrane

14.

gum; mucous membrane, hypertrophy

15.

gums hypertrophied

16.

hypertrophy of gingiva

17.

hypertrophy; gum

18.

hypertrophy; mucous membrane gum

19.

mucous membrane; gum, hypertrophy

20.

mucous membrane; hypertrophy gum

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Amlodipine	FAERS: 43 Canada Vigilance: 3		Canada Vigilance US FAERS
2	Cyclosporine	FAERS: 20 Canada Vigilance: 3	2566048	CTD Canada Vigilance US FAERS
3	Phenytoin	FAERS: 15 Canada Vigilance: 8	View details 190707 817892 1147459 3951721 4293820 4329415 4996854	CTD Canada Vigilance US FAERS
4	Zoledronic Acid	FAERS: 10		OFFSIDES US FAERS
5	Phenytoin	FAERS: 6		US FAERS
6	Valproic Acid	FAERS: 5 Canada Vigilance: 1		Canada Vigilance US FAERS
7	Amlodipine	FAERS: 4		US FAERS
8	Loratadine	FAERS: 3		US FAERS
9	Nifedipine	FAERS: 3 Canada Vigilance: 2		Canada Vigilance US FAERS
10	Azacitidine	FAERS: 2		OFFSIDES US FAERS
11	Clopidogrel	FAERS: 2		US FAERS
12	Hydroxychloroquine	FAERS: 2		US FAERS
13	Lamotrigine	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
14	Raloxifene Hydrochloride	FAERS: 2		US FAERS
15	Sulfasalazine	FAERS: 2		US FAERS
16	Tacrolimus	FAERS: 2		US FAERS
17	Valsartan	FAERS: 2		US FAERS
18	Varenicline	FAERS: 2		US FAERS
19	Vigabatrin	FAERS: 2		OFFSIDES US FAERS
20	Alendronate	FAERS: 1		US FAERS
21	Carbamazepine	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
22	Deferasirox	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
23	Deferiprone	FAERS: 1		US FAERS
24	Diclofenac	FAERS: 1		US FAERS
25	Diltiazem	FAERS: 1		OFFSIDES US FAERS
26	Dimethyl Fumarate	FAERS: 1		US FAERS
27	Duloxetine Hydrochloride	FAERS: 1		US FAERS
28	Felodipine	FAERS: 1		US FAERS
29	Fingolimod Hydrochloride	FAERS: 1		US FAERS
30	Fluticasone/salmeterol	FAERS: 1		US FAERS
31	Gabapentin	FAERS: 1		US FAERS
32	Levetiracetam	FAERS: 1		US FAERS
33	Methylphenidate	FAERS: 1		US FAERS
34	Mycophenolic Acid	FAERS: 1		US FAERS
35	Oseltamivir	FAERS: 1		US FAERS
36	Pregabalin	FAERS: 1		US FAERS
37	Simvastatin	FAERS: 1		US FAERS
38	Sirolimus	FAERS: 1		US FAERS
39	Teriparatide	FAERS: 1		US FAERS
40	Valproic Acid	FAERS: 1		US FAERS
41	Vemurafenib	FAERS: 1		US FAERS
42	Verapamil	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
43	trametinib	FAERS: 1		US FAERS
44	5-O-[1-[3,3-Diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydron;chloride			OFFSIDES
45	Acyclovir			OFFSIDES
46	Amoxicillin-Potassium Clavulanate Combination	Canada Vigilance: 1		Canada Vigilance
47	Ampicillin	Canada Vigilance: 1		Canada Vigilance
48	Ascorbic Acid	Canada Vigilance: 1		Canada Vigilance
49	Azathioprine			OFFSIDES
50	Aztreonam			OFFSIDES
51	Bortezomib			SIDER
52	Castor Oil	Canada Vigilance: 1		Canada Vigilance
53	Ceftazidime			OFFSIDES
54	Clobazam			OFFSIDES
55	Clotrimazole			OFFSIDES
56	Cyclophosphamide			OFFSIDES
57	Cyproheptadine	Canada Vigilance: 1		Canada Vigilance
58	Cytarabine			OFFSIDES
59	Dantrolene			OFFSIDES
60	Daunorubicin			OFFSIDES
61	Dexamethasone			OFFSIDES
62	Diazoxide		2040926	CTD
63	Docetaxel			OFFSIDES
64	Doxepin			OFFSIDES
65	Doxorubicin			OFFSIDES
66	Enalapril			OFFSIDES
67	Erythromycin			OFFSIDES
68	Ethosuximide			SIDER
69	Everolimus			SIDER
70	Folic Acid			OFFSIDES
71	Medroxyprogesterone Acetate			OFFSIDES
72	Melphalan			OFFSIDES
73	Minocycline			OFFSIDES
74	Mitoxantrone			OFFSIDES
75	Nitrazepam			OFFSIDES
76	Pamidronate			OFFSIDES
77	Penicillin V			OFFSIDES
78	Phenobarbital			OFFSIDES
79	Pindolol			OFFSIDES
80	Prazosin			OFFSIDES
81	Prednisone			OFFSIDES
82	Primidone			OFFSIDES
83	Raloxifene Hydrochloride			OFFSIDES
84	Ranitidine			OFFSIDES
85	Sildenafil Citrate			OFFSIDES
86	Sodium Bicarbonate			OFFSIDES
87	Tetracycline	Canada Vigilance: 1		Canada Vigilance
88	Thalidomide			OFFSIDES
89	Topiramate	Canada Vigilance: 1		Canada Vigilance
90	Trimethoprim, Sulfamethoxazole Drug Combination	Canada Vigilance: 1		Canada Vigilance
91	Vancomycin			OFFSIDES
92	Verapamil	Canada Vigilance: 1		Canada Vigilance
93	Vincristine			OFFSIDES
94	bicalutamide			OFFSIDES
95	calcium acetate			OFFSIDES
96	desloratadine			OFFSIDES
97	eicosapentaenoic acid ethyl ester			OFFSIDES
98	erythromycin lactobionate			OFFSIDES
99	ethotoin			SIDER
100	fluphenazine depot			OFFSIDES
101	fudosteine			OFFSIDES
102	lercanidipine			SIDER
103	samarium Sm-153 lexidronam			OFFSIDES
104	temocapril hydrochloride			OFFSIDES
105	terconazole			OFFSIDES
106	valdecoxib	Canada Vigilance: 1		Canada Vigilance
107	voglibose			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Gingival Hyperplasia	49.2%
2	Gingivitis	36%
3	Pericoronitis	36%
4	Gingival Recession	35.3%
5	Gingival Atrophy	35.3%
6	Periodontitis	28.5%
7	Peri-Implantitis	28.5%
8	Tooth Loss	24.6%
9	Gingival Hemorrhage	24.3%
10	Burning Mouth Syndrome	22.7%
11	Lip Diseases	22.7%
12	Microglossia	22.7%
13	Oral Submucous Fibrosis	22.7%
14	Salivary Gland Diseases	22.7%
15	Stomatitis	22.7%
16	Tongue Diseases	22.7%
17	Oral Ulcer	22.7%
18	Giant Cell Epulis	18.2%
19	Facial Hemiatrophy	17.6%
20	Melkersson-Rosenthal Syndrome	17.6%
21	Aggressive Periodontitis	16.8%
22	Facial Nerve Diseases	15.4%
23	Granulomatosis, Orofacial	15.4%
24	Mouth Abnormalities	15.3%
25	Tooth Diseases	15.3%
26	Oral candidiasis	15.1%
27	Mouth Neoplasms	15.1%
28	Oral Fistula	15.1%
29	Lichen Planus, Oral	14.8%
30	Bell Palsy	14%
31	Salivary Gland Fistula	12.2%
32	Salivary Gland Neoplasms	12.2%
33	Ulcerative stomatitis	12.2%
34	Tongue Neoplasms	12.2%
35	Cheilitis	12.2%
36	Drooling	12.2%
37	Glossitis	12.2%
38	Macroglossia	12.2%
39	Sialadenitis	12.2%
40	Sialometaplasia, Necrotizing	12.2%
41	Sialorrhea	12.2%
42	Aphthous Stomatitis	12.2%
43	Xerostomia	12.2%
44	Glossoptosis	12.2%
45	Alveolar Bone Loss	11.4%
46	Facial paralysis	11.2%
47	Facial Paresis	11.2%
48	Hemifacial Spasm	11.1%
49	Jaw Diseases	10.7%
50	Pharyngeal Diseases	10.7%
51	Parotitis	9.6%
52	Parotid Neoplasms	8.7%
53	Facial Neuralgia	8.2%
54	Macrostomia	8.2%
55	Microstomia	8.2%
56	Dental Fistula	8.1%
57	Oroantral Fistula	8.1%
58	Bruxism	7.6%
59	Dental Leakage	7.6%
60	Hypercementosis	7.6%
61	Malocclusion	7.6%
62	Tooth Crowding	7.6%
63	Tooth Discoloration	7.6%
64	Tooth Demineralization	7.6%
65	Tooth Ankylosis	7.6%
66	Radicular Cyst	7.5%
67	Glossitis, Benign Migratory	7.2%
68	Vesicular Stomatitis	6.4%
69	Behcet Syndrome	6.4%
70	Temporomandibular Joint Disorders	5.7%
71	Tooth Injuries	5.4%
72	Maxillary Diseases	5.1%
73	Tooth Resorption	5.1%
74	Mobius Syndrome	5%
75	Herpes Zoster Oticus	5%
76	Toothache	4.9%
77	Leukoplakia, Oral	4.9%
78	Herpes Labialis	4.9%
79	Trigeminal Nerve Disorder	4.8%
80	Palatal Neoplasms	4.6%
81	Cleft Palate	4.5%
82	Facial Nerve Injuries	4.1%
83	Dental Enamel Hypoplasia	4.1%
84	Hypodontia	4.1%
85	Dental caries	4.1%
86	Dental Plaque	4.1%
87	Dental Pulp Calcification	4.1%
88	Pulpitis	4.1%
89	Tooth Erosion	4.1%
90	Pharyngitis	3.9%
91	Toxic Epidermal Necrolysis	3.5%
92	Stevens-Johnson Syndrome	3.5%
93	Jaw Abnormalities	3.3%
94	Mumps	3.2%
95	Trigeminal Neuralgia	3.2%
96	Pharyngeal Neoplasms	3.1%
97	Maxillofacial Abnormalities	3%
98	Tooth Avulsion	2.8%
99	Nasopharyngitis	2.8%
100	Dental Pulp Necrosis	2.7%
101	Retrognathia	2.6%
102	Temporomandibular Joint Dysfunction Syndrome	2.6%
103	Nasopharyngeal Neoplasms	2.3%
104	Prognathism	2.3%
105	Lemierre Syndrome	2.1%
106	Sicca Syndrome	2.1%
107	Sjogren's Syndrome	2.1%
108	Tonsillitis	2.1%
109	Sleep Bruxism	2.1%
110	Micrognathism	1.8%
111	Pierre Robin Syndrome	1.8%
112	Retropharyngeal Abscess	1.6%
113	Hypopharyngeal Neoplasms	1.6%
114	Hypopharyngeal Cancer	1.6%
115	Nasopharyngeal carcinoma	1.2%
116	Peritonsillar Abscess	1%
117	Tonsillar Neoplasms	1%
118	Basal Cell Nevus Syndrome	0.5%

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