MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Panophthalmitis

(UMLS:C0030332)

Definition:: Acute suppurative inflammation of the inner eye with necrosis of the sclera (and sometimes the cornea) and extension of the inflammation into the orbit. Pain may be severe and the globe may rupture. In endophthalmitis the globe does not rupture.
UMLS ID:: C0030332
MeSH ID:: D010202

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.354.900.675|C01.539.375.354.900.675|C01.539.375.450.900.675|C01.703.343.900.675

Classification 2:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.294.354.900.675|C11.294.450.900.675|C11.941.879.960.580

Synonym(s)

Panophthalmitis

Entire eye inflamed

Inflammation of entire eye

panophthalmitis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Dexamethasone	FAERS: 3		SIDER US FAERS
2	Fingolimod Hydrochloride	FAERS: 3		US FAERS
3	Triamcinolone Acetonide	FAERS: 3		US FAERS
4	telaprevir	FAERS: 3		US FAERS
5	Dronedarone	FAERS: 1		US FAERS
6	Gatifloxacin	FAERS: 1		SIDER US FAERS
7	Ibandronic Acid	FAERS: 1		SIDER US FAERS
8	Ivermectin	FAERS: 1		US FAERS
9	PCI 32765	FAERS: 1		US FAERS
10	Tacrolimus	FAERS: 1		US FAERS
11	Triamcinolone	FAERS: 1		SIDER US FAERS
12	liposomal amphotericin B	FAERS: 1		US FAERS
13	Acamprosate			SIDER
14	Aspirin, Dipyridamole Drug Combination			OFFSIDES
15	Betaxolol			SIDER
16	Bisacodyl			OFFSIDES
17	Bortezomib			SIDER
18	Bosentan			SIDER
19	Ciprofloxacin			SIDER
20	Diltiazem			SIDER
21	Fentanyl			OFFSIDES
22	Galactose			OFFSIDES
23	Ketorolac			SIDER
24	Latanoprost			OFFSIDES
25	Methamphetamine		19384581	CTD
26	Metoclopramide			OFFSIDES
27	Moxifloxacin			SIDER
28	Olanzapine			SIDER
29	Piperacillin, Tazobactam Drug Combination			OFFSIDES
30	Pravastatin			SIDER
31	Prednisone			SIDER
32	Propafenone			SIDER
33	Ribavirin			OFFSIDES
34	Riluzole			SIDER
35	Risedronic Acid			SIDER
36	Sevelamer			OFFSIDES
37	Sevelamer			OFFSIDES
38	Temazepam			OFFSIDES
39	Travoprost			SIDER
40	Vildagliptin			OFFSIDES
41	Zalcitabine			SIDER
42	brinzolamide			OFFSIDES
43	difluprednate			SIDER
44	fluocinolone			SIDER
45	pegaptanib			SIDER
46	prednisolone acetate			OFFSIDES
47	sitaxsentan			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Hordeolum	33.8%
2	Bacterial conjunctivitis	31.9%
3	Corneal Ulcer	27.8%
4	Endophthalmitis	27.5%
5	Trachoma	23.6%
6	Ophthalmia Neonatorum	19.9%
7	Dermatomycoses	16.3%
8	Skin Diseases, Bacterial	16.3%
9	Bacteremia	16.3%
10	Central Nervous System Bacterial Infections	15.8%
11	Mycetoma	15.7%
12	Pelvic Infection	15%
13	Wound Infection	15%
14	Soft Tissue Infection	15%
15	Community-Acquired Infections	15%
16	Bacterial Endocarditis	15%
17	Ulcerative stomatitis	14.6%
18	Candidiasis, Chronic Mucocutaneous	13.8%
19	Cutaneous Candidiasis	13.8%
20	Hidradenitis Suppurativa	13.7%
21	Respiratory Tract Infections	13.7%
22	Bone Diseases, Infectious	13.5%
23	Pregnancy Complications, Infectious	13.5%
24	Skin Diseases, Infectious	13.5%
25	Arthritis, Infectious	13.4%
26	Suppuration	13.4%
27	Cross Infection	13.4%
28	Septicemia	13.4%
29	Sepsis	13.4%
30	Uveal Neoplasms	13.2%
31	Central Nervous System Infection	13%
32	Syphilis	12.9%
33	Pars Planitis	12.6%
34	Opportunistic Infections	12.6%
35	Cellulitis	12.5%
36	Retinal Dysplasia	12.4%
37	Erythema Chronicum Migrans	12.4%
38	Aniridia	12.4%
39	Candidemia	12.3%
40	Fungemia	12.3%
41	Borrelia Infections	12.2%
42	Leptospirosis	12.2%
43	Urinary tract infection	12.2%
44	Erysipelas	12%
45	Staphylococcal Skin Infections	12%
46	Aspergillosis	11.8%
47	Candidiasis	11.8%
48	Coccidioidomycosis	11.8%
49	Histoplasmosis	11.8%
50	Paracoccidioidomycosis	11.8%
51	Zygomycosis	11.8%
52	Gram-Negative Bacterial Infections	11.8%
53	Gram-Positive Bacterial Infections	11.8%
54	Phaeohyphomycosis	11.8%
55	Pneumocystis Infections	11.8%
56	Blastomycosis	11.7%
57	Panophthalmitis	11.5%
58	Sexually Transmitted Diseases	11.3%
59	Asthenopia	11.2%
60	Conjunctival Diseases	11.2%
61	Corneal Diseases	11.2%
62	Eyelid Diseases	11.2%
63	Lacrimal Apparatus Diseases	11.2%
64	Lens Diseases	11.2%
65	Ocular Hypertension	11.2%
66	Ocular Hypotension	11.2%
67	Retinal Diseases	11.2%
68	Scleral Diseases	11.2%
69	Vitreous Detachment	11.2%
70	Posterior Vitreous Detachment	11.2%
71	Erythrasma	11.1%
72	Ecthyma	11.1%
73	Subacute Bacterial Endocarditis	11.1%
74	Chlamydia Infections	11%
75	Gonorrhea	11%
76	Neuroaspergillosis	11%
77	Lyme Neuroborreliosis	11%
78	Retinal Degeneration	10.9%
79	Endotoxemia	10.9%
80	Panuveitis	10.9%
81	Iridocorneal endothelial syndrome	10.9%
82	Bacterial Infections	10.7%
83	Mycoses	10.7%
84	Lyme Disease	10.6%
85	Relapsing Fever	10.6%
86	Otomycosis	10.6%
87	Piedra	10.5%
88	Central Nervous System Fungal Infections	10.5%
89	Bacterial Vaginosis	10.5%
90	Pertussis	10.4%
91	Impetigo	10.4%
92	Choroiditis	10.2%
93	Iridocyclitis	10.2%
94	Iritis	10.2%
95	Choroid Diseases	10.2%
96	Iris Diseases	10.2%
97	Eye Abnormalities	10%
98	Eye Manifestations	10%
99	Eye Neoplasms	10%
100	Optic Neuropathy	10%
101	Blepharophimosis	9.9%
102	Eyelid Neoplasms	9.8%
103	Retinal Hemorrhage	9.8%
104	Choroid Hemorrhage	9.8%
105	Chorioretinitis	9.7%
106	Chromoblastomycosis	9.7%
107	Dermatophytosis	9.7%
108	Sporotrichosis	9.7%
109	Tinea	9.7%
110	Tinea Versicolor	9.7%
111	Trichophytosis	9.7%
112	Hyalohyphomycosis	9.7%
113	Neurosyphilis	9.6%
114	Lung Diseases, Fungal	9.6%
115	Brain Abscess	9.5%
116	Pneumonia, Bacterial	9.5%
117	Ocular Motility Disorders	9.1%
118	Cyclophoria	9.1%
119	Invasive Pulmonary Aspergillosis	9%
120	Pupil Disorders	9%
121	Duane Retraction Syndrome	9%
122	Eye Hemorrhage	8.9%
123	Rhinoscleroma	8.9%
124	Acanthamoeba Keratitis	8.9%
125	Vision Disorders	8.9%
126	Metamorphopsia	8.9%
127	Visual Impairment	8.9%
128	Keratitis, Herpetic	8.9%
129	Cytomegalovirus Retinitis	8.9%
130	Corneal Scar	8.9%
131	Eye Injuries	8.9%
132	Joint Tuberculosis	8.9%
133	Tuberculosis, Osteoarticular	8.9%
134	Bone Tuberculosis	8.9%
135	Uveomeningoencephalitic Syndrome	8.8%
136	Xerophthalmia	8.7%
137	Low Tension Glaucoma	8.7%
138	Meningitis, Cryptococcal	8.2%
139	Staphylococcal Scalded Skin Syndrome	8.2%
140	Human Ehrlichiosis	7.9%
141	Retinoblastoma	7.7%
142	Peritonitis	7.6%
143	Osteomyelitis	7.6%
144	Periostitis	7.6%
145	Surgical Wound Infection	7.6%
146	Furunculosis	7.5%
147	furuncle	7.5%
148	Abscess	7.5%
149	Adnexitis	7.5%
150	Empyema	7.5%
151	Pelvic Inflammatory Disease	7.5%
152	Lymphogranuloma Venereum	7.5%
153	Infection	7.4%
154	Human anaplasmosis	7.2%
155	Anterior uveitis	7.2%
156	Uveitis, Posterior	7.2%
157	Color blindness	7.1%
158	Eye Infection	7%
159	Superinfection	6.9%
160	Actinomycetales Infections	6.9%
161	Bordetella Infections	6.9%
162	Brucellosis	6.9%
163	Campylobacter infection	6.9%
164	Clostridium Infections	6.9%
165	Enterobacteriaceae Infections	6.9%
166	Listeriosis	6.9%
167	Mucormycosis	6.9%
168	Pseudomonas Infections	6.9%
169	Q Fever	6.9%
170	Staphylococcal Infections	6.9%
171	Streptococcal Infections	6.9%
172	Vibrio Infections	6.9%
173	Helicobacter Infections	6.9%
174	Bacillaceae Infections	6.9%
175	Neisseriaceae Infections	6.9%
176	Burkholderia Infections	6.9%
177	Clostridium difficile infection	6.9%
178	Flavobacteriaceae Infections	6.9%
179	Moraxellaceae Infections	6.9%
180	Burkholderia cepacia Infection	6.9%
181	Retinitis Pigmentosa	6.8%
182	Pigmentary retinopathy	6.8%
183	Herpes Zoster Ophthalmicus	6.8%
184	Puerperal Infection	6.8%
185	Spondylitis	6.8%
186	Appendicitis	6.8%
187	Bacteriuria	6.8%
188	Pyuria	6.8%
189	Pyomyositis	6.8%
190	Keratoconjunctivitis Sicca	6.8%
191	Japanese Spotted Fever	6.8%
192	Endotoxic shock	6.8%
193	Septic Shock	6.8%
194	Toxic Shock Syndrome	6.8%
195	Keratoconjunctivitis	6.5%
196	Meningitis, Listeria	6.4%
197	Fusariosis	6.4%
198	Erysipelothrix infection	6.2%
199	carbuncle	6.2%
200	Oral candidiasis	6.2%
201	Arthritis, Reactive	6.1%
202	Pulmonary Aspergillosis	6.1%
203	Bronchopulmonary Aspergillosis	6.1%
204	Angioid Streaks	6.1%
205	Anisometropia	6.1%
206	Aphakia	6.1%
207	Astigmatism	6.1%
208	Blepharitis	6.1%
209	Blepharoptosis	6.1%
210	Blepharospasm	6.1%
211	Conjunctivitis	6.1%
212	Corneal edema	6.1%
213	Corneal Opacity	6.1%
214	Dacryocystitis	6.1%
215	Dry Eye Syndromes	6.1%
216	Ectropion	6.1%
217	Enophthalmos	6.1%
218	Entropion	6.1%
219	Episcleritis	6.1%
220	Exophthalmos	6.1%
221	Glaucoma	6.1%
222	Keratitis	6.1%
223	Keratoconus	6.1%
224	Lacrimal Duct Obstruction	6.1%
225	Lens dislocation	6.1%
226	Lens Subluxation	6.1%
227	Mydriasis	6.1%
228	Myopia	6.1%
229	Presbyopia	6.1%
230	Pterygium	6.1%
231	Retinal Detachment	6.1%
232	Retinitis	6.1%
233	Scleritis	6.1%
234	Corneal Neovascularization	6.1%
235	Orbital Pseudotumor	6.1%
236	Cataract	6.1%
237	Pinguecula	6.1%
238	Trichiasis	6.1%
239	Exfoliation Syndrome	6%
240	Erythema Induratum	5.9%
241	Tinea Capitis	5.8%
242	Onychomycosis	5.8%
243	AIDS-Related Opportunistic Infections	5.7%
244	Meningitis, Haemophilus	5.5%
245	Meningitis, Pneumococcal	5.5%
246	Meningitis, Bacterial	5.5%
247	Meningitis, Fungal	5.5%
248	Tuberculosis, Spinal	5.5%
249	Candidiasis, Vulvovaginal	5.5%
250	Anophthalmos	5.4%
251	Microphthalmos	5.4%
252	Optic Atrophy	5.4%
253	Optic Neuritis	5.4%
254	Papilledema	5.4%
255	Pemphigoid, Benign Mucous Membrane	5.4%
256	Retinal Artery Occlusion	5.4%
257	Retinopathy of Prematurity	5.4%
258	Strabismus	5.4%
259	Tolosa-Hunt Syndrome	5.4%
260	Orbital Cellulitis	5.4%
261	Retinal Vasculitis	5.4%
262	Hypertensive Retinopathy	5.4%
263	Retrobulbar Hemorrhage	5.4%
264	Corneal Endothelial Cell Loss	5.4%
265	Hyphema	5.4%
266	Retinal Neovascularization	5.4%
267	Vitreous Hemorrhage	5.4%
268	Choroidal Neovascularization	5.4%
269	Tinea Pedis	5.3%
270	Corneal Perforation	5.3%
271	Psoas Abscess	5.2%
272	Abdominal Abscess	5.2%
273	Syphilis, Congenital	5.2%
274	Rocky Mountain Spotted Fever	5.2%
275	Optic Neuropathy, Ischemic	4.9%
276	Anterior Ischemic Optic Neuropathy	4.9%
277	Retinal Vein Occlusion	4.9%
278	Anisocoria	4.9%
279	Diabetic Retinopathy	4.9%
280	Tonic Pupil	4.9%
281	Eye pain	4.9%
282	Orbital Myositis	4.9%
283	Diplopia	4.9%
284	Scotoma	4.9%
285	Photophobia	4.9%
286	Amaurosis	4.9%
287	Blindness	4.9%
288	Diverticulitis	4.6%
289	Toxoplasmosis, Cerebral	4.6%
290	Tuberculosis, Meningeal	4.5%
291	Ophthalmoplegia	4.5%
292	External Ophthalmoplegia	4.5%
293	Amblyopia	4.4%
294	Acinetobacter Infections	4.4%
295	Actinomycosis	4.4%
296	Bacteroides Infections	4.4%
297	Cholera	4.4%
298	Corynebacterium Infections	4.4%
299	Escherichia coli Infections	4.4%
300	Gas Gangrene	4.4%
301	Haemophilus Infections	4.4%
302	Klebsiella Infections	4.4%
303	Meningococcal Infections	4.4%
304	Mycobacterium Infections	4.4%
305	Mycoplasma Infections	4.4%
306	Nocardia Infections	4.4%
307	Pasteurella Infections	4.4%
308	Pneumococcal Infections	4.4%
309	Proteus Infections	4.4%
310	Rickettsia Infections	4.4%
311	Salmonella infections	4.4%
312	Scarlet Fever	4.4%
313	Scrub Typhus	4.4%
314	Tetanus	4.4%
315	Serratia Infections	4.4%
316	Ureaplasma Infections	4.4%
317	Pulmonary Nocardiosis	4.4%
318	Lung Abscess	4.3%
319	Diverticulum	4.2%
320	Diverticulosis	4.2%
321	Discitis	4.2%
322	Mastoiditis	4.2%
323	Petrositis	4.2%
324	Uveitis	4.1%
325	Retropharyngeal Abscess	3.8%
326	Epidural Abscess	3.8%
327	Peritonsillar Abscess	3.8%
328	Aicardi's syndrome	3.8%
329	Angle Closure Glaucoma	3.6%
330	Glaucoma, Open-Angle	3.6%
331	Macular degeneration	3.6%
332	Retinal Drusen	3.6%
333	Retinal Necrosis Syndrome, Acute	3.6%
334	Retinoschisis	3.6%
335	Rheumatic Fever	3.6%
336	Enterocolitis, Pseudomembranous	3.5%
337	pseudomembranous colitis	3.5%
338	Dysentery, Bacillary	3.5%
339	Opsoclonus-Myoclonus Syndrome	3.5%
340	Albinism	3.5%
341	Optic Atrophy, Hereditary, Leber	3.5%
342	Behcet Syndrome	3.4%
343	Botulism	3.3%
344	Liver Abscess	3.2%
345	Miller Fisher Syndrome	3.2%
346	Esotropia	3.2%
347	Exotropia	3.2%
348	Diphtheria	3.2%
349	Leprosy	3.2%
350	Mycobacterium Infections, Nontuberculous	3.2%
351	Psittacosis	3.2%
352	Paratyphoid Fever	3.2%
353	Plague	3.2%
354	Tuberculosis	3.2%
355	Typhoid Fever	3.2%
356	TYPHUS	3.2%
357	Yersinia pseudotuberculosis Infections	3.2%
358	Bubonic Plague	3.2%
359	Mycobacterium abscessus Infection	3.2%
360	Aspergillosis, Allergic Bronchopulmonary	3%
361	CHARGE Syndrome	2.9%
362	Congenital nystagmus	2.9%
363	Salmonella Infections, Animal	2.9%
364	Waterhouse-Friderichsen Syndrome	2.9%
365	Hemianopsia	2.9%
366	Amaurosis Fugax	2.9%
367	Blindness, Cortical	2.9%
368	Rheumatic Heart Disease	2.9%
369	Salmonella food poisoning	2.9%
370	Graves Disease	2.7%
371	Horner Syndrome	2.7%
372	Mandibulofacial Dysostosis	2.6%
373	Mycobacterium avium-intracellulare Infection	2.6%
374	Lymph Node Tuberculosis	2.6%
375	Tuberculosis, Miliary	2.6%
376	Tuberculosis, Multidrug-Resistant	2.6%
377	Leprosy, Multibacillary	2.6%
378	Latent Tuberculosis	2.6%
379	Tuberculosis, Gastrointestinal	2.3%
380	Tuberculosis, Central Nervous System	2.3%
381	Borderline leprosy	2.3%
382	Leprosy, Lepromatous	2.3%
383	Tuberculoid leprosy	2.3%
384	Extensively Drug-Resistant Tuberculosis	2.3%
385	Sicca Syndrome	2.2%
386	Sjogren's Syndrome	2.2%
387	Tuberculosis, Pulmonary	2.1%
388	Ophthalmoplegic Migraine	2.1%
389	Progressive supranuclear palsy	2.1%
390	Lemierre Syndrome	2%
391	Kearns-Sayre syndrome	2%
392	Neuromyelitis Optica	1.9%
393	Liver Abscess, Amebic	1.9%
394	Alstrom Syndrome	1.8%
395	Optic Nerve Glioma	1.7%
396	Tuberculosis, Renal	1.6%

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