MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lacrimal Duct Obstruction

(UMLS:C0022906)

Definition:: Interference with the secretion of tears by the lacrimal glands. Obstruction of the LACRIMAL SAC or NASOLACRIMAL DUCT causing acute or chronic inflammation of the lacrimal sac (DACRYOCYSTITIS). It is caused also in infants by failure of the nasolacrimal duct to open into the inferior meatus and occurs about the third week of life. In adults occlusion may occur spontaneously or after injury or nasal disease. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p250)
UMLS ID:: C0022906
MeSH ID:: D007767

Classification:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.496.456

Synonym(s)

Lacrimal Duct Obstruction

Blocked lacrimal canaliculus

Blocked tear duct

Canalicular obstruction

LACRIMAL DUCT OBSTRUCTION

Lacrimal canalicular obstruction

Lacrimal duct obstruction

Obstructed canaliculus

Obstruction of lacrimal canaliculi

10.

Obstruction of lacrimal canaliculus

11.

Obstruction of lacrimal duct

12.

Obstuction of lacrimal ducts

13.

blocked ducts tear

14.

blocked tear duct

15.

lacrimal duct obstruction

16.

lacrimal obstruction duct

17.

lacrimal passages; obstruction

18.

lacrimal passages; occlusion

19.

obstruction; lacrimal passages

20.

occlusion; lacrimal passages

21.

tear duct blocked

22.

tear duct occlusion

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Cocaine		10604666	CTD
2	Docetaxel			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Dacryocystitis	42.9%
2	Dry Eye Syndromes	42.9%
3	Xerophthalmia	30.2%
4	Keratoconjunctivitis Sicca	23.3%
5	Asthenopia	23.1%
6	Conjunctival Diseases	23.1%
7	Corneal Diseases	23.1%
8	Eyelid Diseases	23.1%
9	Lens Diseases	23.1%
10	Ocular Hypertension	23.1%
11	Ocular Hypotension	23.1%
12	Retinal Diseases	23.1%
13	Scleral Diseases	23.1%
14	Vitreous Detachment	23.1%
15	Posterior Vitreous Detachment	23.1%
16	Retinal Degeneration	19%
17	Low Tension Glaucoma	16.3%
18	Iridocorneal endothelial syndrome	16.3%
19	Eye Abnormalities	15%
20	Eye Infection	15%
21	Eye Manifestations	15%
22	Eye Neoplasms	15%
23	Optic Neuropathy	15%
24	Angioid Streaks	14.3%
25	Anisometropia	14.3%
26	Aphakia	14.3%
27	Astigmatism	14.3%
28	Blepharitis	14.3%
29	Blepharoptosis	14.3%
30	Blepharospasm	14.3%
31	Choroid Diseases	14.3%
32	Conjunctivitis	14.3%
33	Corneal edema	14.3%
34	Corneal Opacity	14.3%
35	Ectropion	14.3%
36	Enophthalmos	14.3%
37	Entropion	14.3%
38	Episcleritis	14.3%
39	Exophthalmos	14.3%
40	Glaucoma	14.3%
41	Iris Diseases	14.3%
42	Keratitis	14.3%
43	Keratoconus	14.3%
44	Lens dislocation	14.3%
45	Lens Subluxation	14.3%
46	Mydriasis	14.3%
47	Myopia	14.3%
48	Presbyopia	14.3%
49	Pterygium	14.3%
50	Retinal Detachment	14.3%
51	Retinitis	14.3%
52	Scleritis	14.3%
53	Uveitis	14.3%
54	Corneal Neovascularization	14.3%
55	Orbital Pseudotumor	14.3%
56	Cataract	14.3%
57	Pinguecula	14.3%
58	Trichiasis	14.3%
59	Blepharophimosis	14%
60	Uveal Neoplasms	14%
61	Retinal Dysplasia	14%
62	Eyelid Neoplasms	13.9%
63	Retinal Hemorrhage	13.9%
64	Keratoconjunctivitis	13.6%
65	Aniridia	12.6%
66	Chorioretinitis	12.6%
67	Corneal Ulcer	12.1%
68	Choroid Hemorrhage	12%
69	Choroiditis	11.7%
70	Iridocyclitis	11.7%
71	Iritis	11.7%
72	Pars Planitis	11.7%
73	Duane Retraction Syndrome	11.1%
74	Ocular Motility Disorders	11.1%
75	Retinitis Pigmentosa	11.1%
76	Cyclophoria	11.1%
77	Pigmentary retinopathy	11.1%
78	Pupil Disorders	10.9%
79	Corneal Scar	10.9%
80	Eye Hemorrhage	10.7%
81	Vision Disorders	10.6%
82	Metamorphopsia	10.6%
83	Visual Impairment	10.6%
84	Eye Injuries	10.5%
85	Angle Closure Glaucoma	10.3%
86	Glaucoma, Open-Angle	10.3%
87	Macular degeneration	10.3%
88	Panuveitis	10.3%
89	Retinal Drusen	10.3%
90	Retinal Necrosis Syndrome, Acute	10.3%
91	Retinoschisis	10.3%
92	Exfoliation Syndrome	10.3%
93	Hordeolum	9.5%
94	Color blindness	9.4%
95	Anophthalmos	9.3%
96	Endophthalmitis	9.3%
97	Microphthalmos	9.3%
98	Optic Atrophy	9.3%
99	Optic Neuritis	9.3%
100	Papilledema	9.3%
101	Pemphigoid, Benign Mucous Membrane	9.3%
102	Retinal Artery Occlusion	9.3%
103	Retinopathy of Prematurity	9.3%
104	Strabismus	9.3%
105	Tolosa-Hunt Syndrome	9.3%
106	Orbital Cellulitis	9.3%
107	Retinal Vasculitis	9.3%
108	Hypertensive Retinopathy	9.3%
109	Retrobulbar Hemorrhage	9.3%
110	Corneal Endothelial Cell Loss	9.3%
111	Hyphema	9.2%
112	Retinal Neovascularization	9.2%
113	Vitreous Hemorrhage	9.2%
114	Sicca Syndrome	8.5%
115	Sjogren's Syndrome	8.5%
116	Trachoma	8.5%
117	Anterior uveitis	8.5%
118	Uveitis, Posterior	8.5%
119	Retinoblastoma	8.3%
120	Acanthamoeba Keratitis	8.2%
121	Keratitis, Herpetic	8.2%
122	Cytomegalovirus Retinitis	8.2%
123	Bacterial conjunctivitis	8.1%
124	Corneal Perforation	7.9%
125	Optic Neuropathy, Ischemic	7%
126	Anterior Ischemic Optic Neuropathy	7%
127	Retinal Vein Occlusion	6.9%
128	Anisocoria	6.8%
129	Diabetic Retinopathy	6.8%
130	Tonic Pupil	6.8%
131	Eye pain	6.8%
132	Orbital Myositis	6.8%
133	Diplopia	6.8%
134	Scotoma	6.8%
135	Photophobia	6.8%
136	Amaurosis	6.8%
137	Blindness	6.8%
138	Esotropia	6.7%
139	Exotropia	6.7%
140	Choroidal Neovascularization	6.7%
141	Panophthalmitis	6.1%
142	Ophthalmoplegia	5.4%
143	External Ophthalmoplegia	5.4%
144	Amblyopia	5.4%
145	Uveomeningoencephalitic Syndrome	5.2%
146	CHARGE Syndrome	5.2%
147	Congenital nystagmus	5.1%
148	Herpes Zoster Ophthalmicus	5.1%
149	Hemianopsia	5%
150	Amaurosis Fugax	4.9%
151	Blindness, Cortical	4.9%
152	Ophthalmia Neonatorum	4.7%
153	Optic Atrophy, Hereditary, Leber	4.5%
154	Graves Disease	4.1%
155	Horner Syndrome	4%
156	Mandibulofacial Dysostosis	3.9%
157	Aicardi's syndrome	3.9%
158	Opsoclonus-Myoclonus Syndrome	3.4%
159	Albinism	3.3%
160	Miller Fisher Syndrome	2.9%
161	Kearns-Sayre syndrome	2.8%
162	Ophthalmoplegic Migraine	2.5%
163	Progressive supranuclear palsy	2.5%
164	Neuromyelitis Optica	2.2%
165	Behcet Syndrome	2.2%
166	Alstrom Syndrome	2%
167	Optic Nerve Glioma	1.8%

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