MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Phenylpropanolamine

(DLNKOYKMWOXYQA-VXNVDRBHSA-N)

Structure

SMILES: O[C@@H](c1ccccc1)[C@H](N)C
Molecular Formula:: C9H13NO
Molecular Weight:: 151.206
Log P:: 1.7675
Hydrogen Bond Acceptor:: 2
Hydrogen Bond Donor:: 2
TPSA:: 46.25
CAS Number(s):: 14838-15-4; 37577-28-9

Synonym(s)

Phenylpropanolamine

Norephedrine

Dexatrim

Phenylpropanolamine Hydrochloride

Prolamine

Propagest

Triaminic DM

Hydrochloride, Phenylpropanolamine

External Link(s)

MeSH	D010665
PubChem Compound	26934
BindingDB	50405613
ChEBI	36
CHEMBL	CHEMBL2092846
KEGG	cpd:C02343
Therapeutic Target Database	D09JXM D04KKT
ZINC	1930

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Acute kidney injury		7109141 7313755	CTD
2	Affective Disorders, Psychotic		2309957	CTD
3	Agitation			SIDER
4	Aneurysm, Ruptured		5813090	CTD
5	Anorexia		17684035 21989786	CTD
6	Antitussive therapy			SIDER
7	Anxiety			SIDER
8	Aphasia		6505775	CTD
9	Apnea		3919189	CTD
10	Arteritis		7613235	CTD
11	Ataxia			SIDER
12	Atrioventricular Block		3989943	CTD
13	Bipolar Disorder		View details 92706 1912131 2768545 3060884 3295932	CTD
14	Cardiac Output, High		3987172	CTD
15	Cardiomyopathies		7055513 7901355	CTD
16	Catatonia		4008454	CTD
17	Cerebral Arterial Diseases		3047837 3822132 7613235	CTD
18	Cerebral Hemorrhage		View details 2099822 2654866 3047837 3822132 3828020 3974900 4013284 4024187 6628226 6695415 7081793 9699397 11117973 11475816 11808351 12791938 16018164	CTD
19	Cerebral Infarction		2042180 3828020 15028328	CTD
20	Cocaine-Related Disorders		17251912	CTD
21	Common Cold		953565	CTD
22	Confusion		92706	CTD
23	Constipation			SIDER
24	Cough suppression			SIDER
25	Dermatitis			SIDER
26	Dizziness			SIDER
27	Drowsiness			SIDER
28	Drug Eruptions		11792017	CTD
29	Drug Overdose		2654866 4093565 7313755	CTD
30	Dystonia		7492048 9007349	CTD
31	Euphoric mood			SIDER
32	Feeling abnormal			SIDER
33	Flushing			SIDER
34	Hallucinations		View details 92706 3447673 7452888 10831490	CTD
35	Headache	Canada Vigilance: 2	View details 3976619 5813089 6428218 6682504 7092186 7114595 11361053	CTD Canada Vigilance
36	Hematoma, Subdural, Intracranial		2956531 9334487	CTD
37	Hemoglobinuria		7109141	CTD
38	Hypersensitivity			SIDER
39	Hypotension, Orthostatic		377035	CTD
40	Hypotension			SIDER
41	Kidney Diseases		7452888	CTD
42	Memory Disorders		6505775	CTD
43	Mental disorders		3828020 6682504	CTD
44	Movement Disorders		7492048	CTD
45	Myocardial Infarction		View details 8780486 11407498 12734532 16267067	CTD
46	Nausea	Canada Vigilance: 1		Canada Vigilance SIDER
47	Nephritis, Interstitial		87921 7109141	CTD
48	Nervousness			SIDER
49	Otitis Media		92706	CTD
50	Proteinuria		7109141	CTD
51	Psychomotor Agitation		7452888	CTD
52	Psychoses, Substance-Induced		View details 92706 3060884 3447673 4098187 4163280 7452888 7995508 10831490	CTD
53	Psychotic Disorders		6628226	CTD
54	Pulmonary Edema		709472 7901355	CTD
55	Pulmonary function test decreased			SIDER
56	Putaminal Hemorrhage		4013284	CTD
57	Renal Insufficiency		87921	CTD
58	Renal tubular necrosis			SIDER
59	Respiratory Depression			SIDER
60	Respiratory Insufficiency		709472	CTD
61	Respiratory Tract Infections		92706	CTD
62	Rhabdomyolysis		7109141	CTD
63	Rhinitis, Allergic, Perennial		4163280	CTD
64	Seizures		View details 295377 2614700 3828020 3919189 6682504 6691429 6848713 7081793 7092186	CTD
65	Serotonin Syndrome			SIDER
66	Sinusitis		2309957	CTD
67	Sleep Wake Disorders		92706	CTD
68	Somnolence			SIDER
69	Subarachnoid Hemorrhage		View details 2956531 4002267 5813090 6695415 9334487 11117973 12791938	CTD
70	Substance-Related Disorders		6124702 6691429	CTD
71	Syncope		9853729	CTD
72	Tachycardia, Paroxysmal		6628226	CTD
73	Tachycardia, Ventricular		6628226 16267067	CTD
74	Tachycardia			SIDER
75	Tension			SIDER
76	Tremor		7452888	CTD SIDER
77	Urinary Retention		3195793	CTD SIDER
78	Urinary hesitation			SIDER
79	Urticaria		11792017	CTD
80	Vascular Headaches		3047837 3822132	CTD
81	Vasculitis, Central Nervous System		View details 2099822 2956531 3974900 11808351	CTD
82	Ventricular Fibrillation		709472 11098973	CTD
83	Vomiting	Canada Vigilance: 1		Canada Vigilance SIDER
84	Weight Gain		24792324	CTD
85	jaundice		7109141	CTD

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