MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Splenosis

(UMLS:C0206369)

Definition:: The spontaneous transplantation of splenic tissue to unusual sites after open splenic trauma, e.g., after automobile accidents, gunshot or stab wounds. The splenic pulp implants appear as red-blue nodules on the peritoneum, omentum, and mesentery, morphologically similar to multifocal pelvic endometriosis. (Segen, Dictionary of Modern Medicine, 1992)
UMLS ID:: C0206369
MeSH ID:: D017890

Classification 1:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.604.744.742.500

Classification 2:

Name:

Wounds and Injuries
MeSH Tree Number(s):: C26.017.680.500|C26.761.555.500

Synonym(s)

Splenosis

splenosis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Imatinib Mesylate	FAERS: 2	US FAERS
2	Finasteride	FAERS: 1	US FAERS
3	Sulpiride		OFFSIDES
4	periciazine		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Frostbite	22.4%
2	Athletic Injuries	17.4%
3	Hand Injuries	17.4%
4	Soft Tissue Injuries	17.4%
5	Sprain	17.4%
6	Sprains and Strains	17.4%
7	Tendon Injuries	17.4%
8	Laceration	17.4%
9	Wounds, Penetrating	17.4%
10	Heat Cramps	17.4%
11	Hypersplenism	17.4%
12	Crush syndrome	16.3%
13	Femoral Fractures	16.3%
14	Tibial Fractures	16.3%
15	Hip Fractures	15.6%
16	Trauma, Nervous System	14.4%
17	Splenic Infarction	14.1%
18	Splenic Neoplasms	14.1%
19	Bites and Stings	14%
20	Extravasation of Diagnostic and Therapeutic Materials	14%
21	Vascular System Injuries	14%
22	Tympanic Membrane Perforation	14%
23	Tooth Injuries	14%
24	Asphyxia	13.8%
25	Esophageal Perforation	13.8%
26	Shock, Traumatic	13.8%
27	Self Mutilation	13.7%
28	Hip Dislocation	13.6%
29	Shoulder Dislocation	13.6%
30	Hip Dysplasia	13.6%
31	Chilblains	13.4%
32	Spinal Fractures	13.4%
33	Uterine Rupture	13.3%
34	Adenitis	12.6%
35	Histiocytosis	12.6%
36	Lymphadenitis	12.6%
37	Lymphangitis	12.6%
38	Lymphedema	12.6%
39	Thymus Hyperplasia	12.6%
40	Pseudolymphoma	12.6%
41	Lymphadenopathy	12.6%
42	Spinal Cord Injuries	11.6%
43	Drowning	11.4%
44	Aortic Rupture	11.3%
45	Iliotibial Band Syndrome	10.6%
46	Uterine Perforation	10.5%
47	Lymphocele	10.2%
48	Lymphoproliferative Disorders	10.2%
49	Lymphatic Abnormalities	10.2%
50	Human Bite	10.1%
51	Contusions	10.1%
52	Decompression Sickness	10.1%
53	Finger Injuries	10.1%
54	Flail Chest	10.1%
55	Fractures, Closed	10.1%
56	Pathological fracture	10.1%
57	Heart Injuries	10.1%
58	Heat Exhaustion	10.1%
59	Heat Stroke	10.1%
60	Knee Injuries	10.1%
61	Foot Injuries	10.1%
62	Decapitation	10.1%
63	Ankle Fracture	10.1%
64	Avulsion fracture	10.1%
65	Compression fracture	10.1%
66	Osteoporotic Fractures	10.1%
67	Thymus Neoplasms	10.1%
68	Lymphangiectasis, Intestinal	9.9%
69	Radiation injury	9.6%
70	Eye Burns	9.3%
71	Rupture	8.7%
72	Mucocutaneous Lymph Node Syndrome	8.4%
73	Craniocerebral Trauma	8.2%
74	Tendinitis	8.2%
75	Lung Injury	8.2%
76	Tendinopathy	8.2%
77	Foreign-Body Reaction	8.1%
78	Insect Bites and Stings	8.1%
79	Paralysis, Obstetric	8.1%
80	Sunburn	8.1%
81	Tooth Avulsion	8.1%
82	Conus Medullaris Syndrome	8.1%
83	Near Drowning	8%
84	Osteoradionecrosis	8%
85	Elephantiasis	7.4%
86	Sarcoidosis	7.4%
87	Elephantiasis Nostras Verrucosa	7.4%
88	Neoplasms, Radiation-Induced	6.9%
89	Brain Concussion	6.8%
90	Splenic Rupture	6.8%
91	Peripheral Nerve Injuries	6.8%
92	Medial Tibial Stress Syndrome	6.8%
93	Agammaglobulinemia	6.7%
94	Central Cord Syndrome	6.7%
95	Pseudarthrosis	6.6%
96	Smoke Inhalation Injury	6.6%
97	Heavy Chain Disease	6%
98	Granuloma	6%
99	Histiocytic Disorders, Malignant	6%
100	Brain Contusion	6%
101	Histiocytosis, Langerhans-Cell	6%
102	Tumor Lysis Syndrome	6%
103	Cardiotoxicity	5.8%
104	Leukemia, Radiation-Induced	5.8%
105	Radiation Pneumonitis	5.7%
106	Radiation Fibrosis	5.7%
107	Infectious Mononucleosis	5.7%
108	Facial Injuries	5.3%
109	Granuloma, Foreign-Body	5.3%
110	Enthesopathy	5.3%
111	Lymphoma	5%
112	Sezary Syndrome	5%
113	Abnormalities, Radiation-Induced	5%
114	Disseminated Intravascular Coagulation	5%
115	Protein S Deficiency	5%
116	Thymoma	4.9%
117	Radiation Injuries, Experimental	4.9%
118	Lymphohistiocytosis, Hemophagocytic	4.9%
119	Erdheim-Chester Disease	4.9%
120	Waldenstrom Macroglobulinemia	4.8%
121	Thrombocythemia, Essential	4.4%
122	Brain Injuries	4.4%
123	Splenosis	4.4%
124	Coma, Post-Head Injury	4.4%
125	Carpal Tunnel Syndrome	4.4%
126	Autoimmune Lymphoproliferative Syndrome	4.3%
127	Anemia	4.2%
128	Blood Coagulation Disorders	4.2%
129	Blood Platelet Disorders	4.2%
130	Bone Marrow Diseases	4.2%
131	Hemorrhagic Disorders	4.2%
132	Leukocyte Disorders	4.2%
133	Methemoglobinemia	4.2%
134	Pancytopenia	4.2%
135	Polycythemia	4.2%
136	Sulfhemoglobinemia	4.2%
137	Thrombophilia	4.2%
138	Erythrocytosis	4.2%
139	Malignant histiocytosis	3.9%
140	Sarcoidosis, Pulmonary	3.9%
141	Histiocytic sarcoma	3.9%
142	Brain Hemorrhage, Traumatic	3.9%
143	Thrombasthenia	3.8%
144	Antithrombin III Deficiency	3.8%
145	Protein C Deficiency	3.8%
146	Transfusion Reaction	3.5%
147	Hypotensive Transfusion Reaction	3.5%
148	Pregnancy Complications, Hematologic	3.4%
149	Hematologic Neoplasms	3.4%
150	Eye Injuries	3.4%
151	Bone Marrow Neoplasms	3.3%
152	Eosinophilic Granuloma	3.3%
153	Thrombocytosis	3.3%
154	Vitamin K Deficiency	3.3%
155	Afibrinogenemia	3.3%
156	Factor VII Deficiency	3.3%
157	Factor X Deficiency	3.3%
158	Factor XII Deficiency	3.3%
159	Hemophilia A	3.3%
160	Activated Protein C Resistance	3.3%
161	Factor II deficiency	3.3%
162	Factor VIII Deficiency	3.3%
163	Factor V deficiency	3.3%
164	Factor XI Deficiency	3.3%
165	Hypoprothrombinemias	3.3%
166	Hodgkin Disease	3.3%
167	Lymphoma, Non-Hodgkin	3.3%
168	Vertebral Artery Dissection	3.3%
169	Leukemia, T-Cell	3.3%
170	Brain Injuries, Diffuse	3.3%
171	Traumatic Brain Injury	3.3%
172	Leukemia, B-Cell	3.3%
173	Cubital Tunnel Syndrome	3.2%
174	Carotid Artery Injuries	2.9%
175	Pneumocephalus	2.8%
176	Olfactory Nerve Injuries	2.8%
177	Composite Lymphoma	2.8%
178	Cerebrospinal Fluid Otorrhea	2.8%
179	Cerebrospinal Fluid Rhinorrhea	2.8%
180	Epilepsy, Post-Traumatic	2.8%
181	Polycythemia Vera	2.8%
182	Lymphangioleiomyomatosis	2.8%
183	Diffuse Axonal Injury	2.7%
184	Hemoglobinuria, Paroxysmal	2.6%
185	Leukemoid Reaction	2.6%
186	Anemia, Hemolytic	2.5%
187	Anemia, Macrocytic	2.5%
188	Eosinophilia	2.5%
189	Hypoproteinemia	2.5%
190	Leukopenia	2.5%
191	Thrombocytopenia	2.5%
192	Leukostasis	2.5%
193	MYELODYSPLASTIC SYNDROME	2.5%
194	Facial Nerve Injuries	2.5%
195	Lymphoma, Follicular	2.4%
196	T-Cell Lymphoma	2.4%
197	Mantle cell lymphoma	2.4%
198	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2.4%
199	Leukemia, Large Granular Lymphocytic	2.4%
200	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2.4%
201	Corneal Scar	2.4%
202	Wiskott-Aldrich Syndrome	2.4%
203	Purpura, Thrombotic Thrombocytopenic	2.3%
204	Anemia, Diamond-Blackfan	2.3%
205	Hematoma, Subdural	2.2%
206	Hematoma, Epidural, Cranial	2.2%
207	Anemia, Sickle Cell	2.1%
208	Thalassemia	2.1%
209	Corneal Perforation	2.1%
210	Lymphoma, T-Cell, Cutaneous	2%
211	Lymphoma, AIDS-Related	2%
212	Enteropathy-Associated T-Cell Lymphoma	2%
213	Primary Effusion Lymphoma	2%
214	Anemia, Neonatal	2%
215	Leukocytosis	2%
216	Paraproteinemias	2%
217	Pelger-Huet Anomaly	2%
218	Pleocytosis	2%
219	Subarachnoid Hemorrhage, Traumatic	1.9%
220	Carotid Artery, Internal, Dissection	1.9%
221	Autoimmune thrombocytopenia	1.9%
222	Immune thrombocytopenic purpura	1.9%
223	Cryoglobulinemia	1.9%
224	Monoclonal Gammopathy of Undetermined Significance	1.9%
225	Mycosis Fungoides	1.8%
226	Lymphomatoid Papulosis	1.8%
227	Plasmablastic lymphoma	1.8%
228	Hematoma, Subdural, Intracranial	1.8%
229	Hematoma, Subdural, Chronic	1.8%
230	Hematoma, Subdural, Acute	1.8%
231	Lymphomatoid Granulomatosis	1.8%
232	Hypergammaglobulinemia	1.7%
233	Transfusion-Related Acute Lung Injury	1.7%
234	Ecchymosis	1.7%
235	Petechiae	1.7%
236	Purpura	1.7%
237	Primary Myelofibrosis	1.6%
238	Agranulocytosis	1.6%
239	Anemia, Megaloblastic	1.6%
240	Lymphocytosis	1.6%
241	Myelofibrosis	1.6%
242	Myeloid Metaplasia	1.6%
243	Hypoalbuminemia	1.6%
244	Hypereosinophilic syndrome	1.6%
245	bone marrow fibrosis	1.6%
246	Thrombotic Microangiopathies	1.6%
247	Purpura, Hyperglobulinemic	1.6%
248	Hemolytic-Uremic Syndrome	1.6%
249	Burkitt Lymphoma	1.5%
250	Sickle Cell Trait	1.5%
251	Hydrops Fetalis	1.5%
252	Multiple Myeloma	1.5%
253	Thrombocytopenic purpura	1.5%
254	Fanconi Anemia	1.4%
255	Waterhouse-Friderichsen Syndrome	1.3%
256	Lymphopenia	1.3%
257	Job Syndrome	1.3%
258	Leukemia, Myelomonocytic, Chronic	1.3%
259	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	1.3%
260	Atypical Hemolytic Uremic Syndrome	1.3%
261	Neutropenia	1.2%
262	Acute Chest Syndrome	1.2%
263	Kernicterus	1.1%
264	Eosinophilia-Myalgia Syndrome	1.1%
265	Niemann-Pick Disease, Type C	1.1%
266	Chronic granulomatous disease	1.1%
267	Shwartzman Phenomenon	1.1%
268	Hemangioma, Cavernous	1.1%
269	Scurvy	1.1%
270	Purpura Fulminans	1.1%
271	Febrile Neutropenia	1%
272	Pulmonary Eosinophilia	1%
273	Eosinophilic Pneumonia	1%
274	Leukemia, Myeloid, Chronic-Phase	1%
275	Anemia, Pernicious	1%
276	POEMS Syndrome	0.9%
277	Pseudoxanthoma Elasticum	0.7%

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