MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukocyte Disorders

(UMLS:C0023510)

Definition:: Disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells.
UMLS ID:: C0023510
MeSH ID:: D007960

Classification:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.378.553

Synonym(s)

Leukocyte Disorders

Disorder of white blood cells, unspecified

Leucocyte disorders

Unspecified disease of white blood cells

WBC diseases

White blood cell disorder

White blood cell disorder, NOS

White blood cell disorder, disease or syndrome

blood cell diseases white

10.

disease (or disorder); white blood cells

11.

disease white blood cell

12.

diseases of white blood cells

13.

leukocyte disorder

14.

leukocyte disorders

15.

wbc disease

16.

white blood cell disease

17.

white blood cell disorder

18.

white blood cell disorders

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Allopurinol	2273607	CTD
2	Busulfan	2273607	CTD
3	Irinotecan	27838229	CTD
4	Levamisole	7218258	CTD
5	carvacrol	27838229	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Disseminated Intravascular Coagulation	45.8%
2	Protein S Deficiency	45.8%
3	Anemia	42.9%
4	Blood Coagulation Disorders	42.9%
5	Blood Platelet Disorders	42.9%
6	Bone Marrow Diseases	42.9%
7	Hemorrhagic Disorders	42.9%
8	Methemoglobinemia	42.9%
9	Pancytopenia	42.9%
10	Polycythemia	42.9%
11	Sulfhemoglobinemia	42.9%
12	Thrombocythemia, Essential	42.9%
13	Thrombophilia	42.9%
14	Erythrocytosis	42.9%
15	Thrombocytosis	37.1%
16	Thrombasthenia	34.2%
17	Antithrombin III Deficiency	34.2%
18	Protein C Deficiency	34.2%
19	Hemoglobinuria, Paroxysmal	33.3%
20	Afibrinogenemia	32%
21	Factor VII Deficiency	32%
22	Factor X Deficiency	32%
23	Factor XII Deficiency	32%
24	Hemophilia A	32%
25	Activated Protein C Resistance	32%
26	Factor II deficiency	32%
27	Factor VIII Deficiency	32%
28	Factor V deficiency	32%
29	Factor XI Deficiency	32%
30	Hypoprothrombinemias	32%
31	Anemia, Hemolytic	31%
32	Anemia, Macrocytic	31%
33	Hypoproteinemia	31%
34	Thrombocytopenia	31%
35	MYELODYSPLASTIC SYNDROME	31%
36	Bone Marrow Neoplasms	30.5%
37	Vitamin K Deficiency	30.1%
38	Transfusion Reaction	30%
39	Hypotensive Transfusion Reaction	30%
40	Polycythemia Vera	29.6%
41	Pregnancy Complications, Hematologic	28.6%
42	Hematologic Neoplasms	28.6%
43	Anemia, Diamond-Blackfan	27.6%
44	Primary Myelofibrosis	25.4%
45	Anemia, Megaloblastic	25.4%
46	Myelofibrosis	25.4%
47	Myeloid Metaplasia	25.4%
48	Hypoalbuminemia	25.4%
49	bone marrow fibrosis	25.4%
50	Thrombotic Microangiopathies	25.4%
51	Purpura, Thrombotic Thrombocytopenic	24%
52	Lymphatic Diseases	23.1%
53	Anemia, Sickle Cell	21.1%
54	Thalassemia	21.1%
55	Anemia, Neonatal	20.9%
56	Paraproteinemias	20.9%
57	Agammaglobulinemia	20.7%
58	Cryoglobulinemia	20%
59	Monoclonal Gammopathy of Undetermined Significance	20%
60	Hemolytic-Uremic Syndrome	18.6%
61	Autoimmune thrombocytopenia	18.4%
62	Immune thrombocytopenic purpura	18.4%
63	Sickle Cell Trait	18.2%
64	Fanconi Anemia	17.9%
65	Heavy Chain Disease	17.6%
66	Waldenstrom Macroglobulinemia	17.1%
67	Atypical Hemolytic Uremic Syndrome	17%
68	Leukemia, Myelomonocytic, Chronic	16.7%
69	Leukemoid Reaction	16.7%
70	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	16.7%
71	Purpura, Hyperglobulinemic	16.5%
72	Thrombocytopenic purpura	16.1%
73	Hypergammaglobulinemia	15.8%
74	Wiskott-Aldrich Syndrome	15.7%
75	Transfusion-Related Acute Lung Injury	15.4%
76	Ecchymosis	15.3%
77	Petechiae	15.3%
78	Purpura	15.3%
79	Leukemia, Myeloid, Chronic-Phase	14.8%
80	Anemia, Pernicious	14.8%
81	Adenitis	14.3%
82	Histiocytosis	14.3%
83	Lymphadenitis	14.3%
84	Lymphangitis	14.3%
85	Lymphedema	14.3%
86	Multiple Myeloma	14.3%
87	Splenic Diseases	14.3%
88	Thymus Hyperplasia	14.3%
89	Pseudolymphoma	14.3%
90	Lymphadenopathy	14.3%
91	Acute Chest Syndrome	13.3%
92	Hydrops Fetalis	13.1%
93	Shwartzman Phenomenon	12.6%
94	Hemangioma, Cavernous	12.5%
95	Scurvy	12.4%
96	Purpura Fulminans	12.4%
97	Waterhouse-Friderichsen Syndrome	10.7%
98	Elephantiasis	10.3%
99	Hypersplenism	10.3%
100	Sarcoidosis	10.3%
101	Elephantiasis Nostras Verrucosa	10.3%
102	Lymphangiectasis, Intestinal	10.2%
103	POEMS Syndrome	10%
104	Lymphocele	9.5%
105	Lymphoproliferative Disorders	9.5%
106	Lymphatic Abnormalities	9.5%
107	Thymus Neoplasms	9.3%
108	Kernicterus	8.7%
109	Lymphohistiocytosis, Hemophagocytic	8.5%
110	Erdheim-Chester Disease	8.5%
111	Granuloma	7%
112	Histiocytic Disorders, Malignant	7%
113	Splenic Infarction	7%
114	Splenic Neoplasms	7%
115	Mucocutaneous Lymph Node Syndrome	6.9%
116	Histiocytosis, Langerhans-Cell	6.8%
117	Tumor Lysis Syndrome	6.8%
118	Pseudoxanthoma Elasticum	6.3%
119	Malignant histiocytosis	5.6%
120	Sarcoidosis, Pulmonary	5.6%
121	Histiocytic sarcoma	5.6%
122	Sezary Syndrome	5.5%
123	Splenic Rupture	5.3%
124	Lymphoma	5.2%
125	Thymoma	5%
126	Splenosis	4.2%
127	Hodgkin Disease	4.2%
128	Lymphoma, Non-Hodgkin	4.2%
129	Autoimmune Lymphoproliferative Syndrome	4.2%
130	Leukemia, T-Cell	4.1%
131	Leukemia, B-Cell	4.1%
132	Infectious Mononucleosis	4%
133	Lymphoma, Follicular	3.7%
134	T-Cell Lymphoma	3.7%
135	Mantle cell lymphoma	3.7%
136	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.7%
137	Leukemia, Large Granular Lymphocytic	3.7%
138	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.7%
139	Lymphoma, T-Cell, Cutaneous	3.5%
140	Lymphoma, AIDS-Related	3.5%
141	Enteropathy-Associated T-Cell Lymphoma	3.5%
142	Primary Effusion Lymphoma	3.5%
143	Mycosis Fungoides	3.3%
144	Lymphomatoid Papulosis	3.3%
145	Plasmablastic lymphoma	3.3%
146	Composite Lymphoma	3.3%
147	Lymphangioleiomyomatosis	3.3%
148	Lymphomatoid Granulomatosis	2.8%
149	Eosinophilic Granuloma	2.8%
150	Burkitt Lymphoma	2.3%
151	Niemann-Pick Disease, Type C	1.3%

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