MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Histiocytosis

(UMLS:C0019618)

Definition:: General term for the abnormal appearance of histiocytes in the blood. Based on the pathological features of the cells involved rather than on clinical findings, the histiocytic diseases are subdivided into three groups: HISTIOCYTOSIS, LANGERHANS CELL; HISTIOCYTOSIS, NON-LANGERHANS-CELL; and HISTIOCYTIC DISORDERS, MALIGNANT.
UMLS ID:: C0019618
MeSH ID:: D015614

Classification:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.604.250

Synonym(s)

Histiocytosis

Histiocytic Infiltrate

Histiocytic Syndrome

Histiocytic infiltrate

Histiocytic infiltrate, NOS

Histiocytic reaction

Histiocytic reaction, NOS

Histiocytosis, NOS

Reticuloendothelial cell infiltrate

10.

Reticuloendothelial cell infiltrate, NOS

11.

Reticulohistiocytosis

12.

histiocytoses

13.

histiocytosis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Carbamazepine	FAERS: 8	US FAERS
2	Clofazimine	FAERS: 2	US FAERS
3	Lamotrigine	FAERS: 2	US FAERS
4	Prednisone	FAERS: 2	US FAERS
5	Clozapine	FAERS: 1	US FAERS
6	Deamino Arginine Vasopressin	FAERS: 1	US FAERS
7	Imatinib Mesylate	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
8	ambrisentan	FAERS: 1	US FAERS
9	Everolimus		SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Adenitis	42.9%
2	Lymphadenitis	42.9%
3	Lymphangitis	42.9%
4	Lymphedema	42.9%
5	Splenic Diseases	42.9%
6	Thymus Hyperplasia	42.9%
7	Pseudolymphoma	42.9%
8	Lymphadenopathy	42.9%
9	Elephantiasis	31%
10	Hypersplenism	31%
11	Sarcoidosis	31%
12	Elephantiasis Nostras Verrucosa	31%
13	Lymphangiectasis, Intestinal	30.5%
14	Lymphocele	28.6%
15	Lymphoproliferative Disorders	28.6%
16	Lymphatic Abnormalities	28.6%
17	Thymus Neoplasms	27.9%
18	Granuloma	20.9%
19	Splenic Infarction	20.9%
20	Splenic Neoplasms	20.9%
21	Agammaglobulinemia	20.7%
22	Mucocutaneous Lymph Node Syndrome	20.7%
23	Tumor Lysis Syndrome	20.5%
24	Heavy Chain Disease	19.3%
25	Sarcoidosis, Pulmonary	16.9%
26	Sezary Syndrome	16.6%
27	Infectious Mononucleosis	16.1%
28	Splenic Rupture	15.8%
29	Lymphoma	15.5%
30	Disseminated Intravascular Coagulation	15.3%
31	Protein S Deficiency	15.3%
32	Thymoma	15.1%
33	Anemia	14.3%
34	Blood Coagulation Disorders	14.3%
35	Blood Platelet Disorders	14.3%
36	Bone Marrow Diseases	14.3%
37	Hemorrhagic Disorders	14.3%
38	Leukocyte Disorders	14.3%
39	Methemoglobinemia	14.3%
40	Pancytopenia	14.3%
41	Polycythemia	14.3%
42	Sulfhemoglobinemia	14.3%
43	Thrombocythemia, Essential	14.3%
44	Thrombophilia	14.3%
45	Erythrocytosis	14.3%
46	Waldenstrom Macroglobulinemia	13.3%
47	Splenosis	12.6%
48	Hodgkin Disease	12.5%
49	Lymphoma, Non-Hodgkin	12.5%
50	Autoimmune Lymphoproliferative Syndrome	12.5%
51	Leukemia, T-Cell	12.4%
52	Leukemia, B-Cell	12.4%
53	Thrombocytosis	12.4%
54	Thrombasthenia	11.4%
55	Antithrombin III Deficiency	11.4%
56	Protein C Deficiency	11.4%
57	Hemoglobinuria, Paroxysmal	11.1%
58	Leukemoid Reaction	11.1%
59	Lymphoma, Follicular	11.1%
60	T-Cell Lymphoma	11.1%
61	Mantle cell lymphoma	11.1%
62	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	11%
63	Leukemia, Large Granular Lymphocytic	11%
64	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	11%
65	Afibrinogenemia	10.7%
66	Factor VII Deficiency	10.7%
67	Factor X Deficiency	10.7%
68	Factor XII Deficiency	10.7%
69	Hemophilia A	10.7%
70	Activated Protein C Resistance	10.7%
71	Factor II deficiency	10.7%
72	Factor VIII Deficiency	10.7%
73	Factor V deficiency	10.7%
74	Factor XI Deficiency	10.7%
75	Hypoprothrombinemias	10.7%
76	Lymphoma, T-Cell, Cutaneous	10.4%
77	Lymphoma, AIDS-Related	10.4%
78	Enteropathy-Associated T-Cell Lymphoma	10.4%
79	Primary Effusion Lymphoma	10.4%
80	Anemia, Hemolytic	10.3%
81	Anemia, Macrocytic	10.3%
82	Eosinophilia	10.3%
83	Hypoproteinemia	10.3%
84	Leukopenia	10.3%
85	Thrombocytopenia	10.3%
86	Leukostasis	10.3%
87	MYELODYSPLASTIC SYNDROME	10.3%
88	Bone Marrow Neoplasms	10.2%
89	Vitamin K Deficiency	10%
90	Mycosis Fungoides	10%
91	Lymphomatoid Papulosis	10%
92	Plasmablastic lymphoma	10%
93	Transfusion Reaction	10%
94	Composite Lymphoma	10%
95	Hypotensive Transfusion Reaction	10%
96	Polycythemia Vera	9.9%
97	Lymphangioleiomyomatosis	9.9%
98	Pregnancy Complications, Hematologic	9.5%
99	Hematologic Neoplasms	9.5%
100	Anemia, Diamond-Blackfan	9.2%
101	Primary Myelofibrosis	8.5%
102	Agranulocytosis	8.5%
103	Anemia, Megaloblastic	8.5%
104	Lymphocytosis	8.5%
105	Myelofibrosis	8.5%
106	Myeloid Metaplasia	8.5%
107	Hypoalbuminemia	8.5%
108	Hypereosinophilic syndrome	8.5%
109	bone marrow fibrosis	8.5%
110	Thrombotic Microangiopathies	8.5%
111	Lymphomatoid Granulomatosis	8.4%
112	Purpura, Thrombotic Thrombocytopenic	8%
113	Neutropenia	7.6%
114	Wiskott-Aldrich Syndrome	7.4%
115	Febrile Neutropenia	7.1%
116	Anemia, Sickle Cell	7%
117	Thalassemia	7%
118	Anemia, Neonatal	7%
119	Leukocytosis	7%
120	Paraproteinemias	7%
121	Pelger-Huet Anomaly	7%
122	Pleocytosis	7%
123	Burkitt Lymphoma	6.9%
124	Cryoglobulinemia	6.7%
125	Monoclonal Gammopathy of Undetermined Significance	6.7%
126	Hemolytic-Uremic Syndrome	6.2%
127	Autoimmune thrombocytopenia	6.1%
128	Immune thrombocytopenic purpura	6.1%
129	Sickle Cell Trait	6.1%
130	Fanconi Anemia	6%
131	Lymphopenia	5.7%
132	Atypical Hemolytic Uremic Syndrome	5.7%
133	Job Syndrome	5.6%
134	Leukemia, Myelomonocytic, Chronic	5.6%
135	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	5.6%
136	Purpura, Hyperglobulinemic	5.5%
137	Thrombocytopenic purpura	5.4%
138	Hypergammaglobulinemia	5.3%
139	Pulmonary Eosinophilia	5.1%
140	Eosinophilic Pneumonia	5.1%
141	Transfusion-Related Acute Lung Injury	5.1%
142	Ecchymosis	5.1%
143	Petechiae	5.1%
144	Purpura	5.1%
145	Leukemia, Myeloid, Chronic-Phase	4.9%
146	Anemia, Pernicious	4.9%
147	Multiple Myeloma	4.8%
148	Acute Chest Syndrome	4.4%
149	Hydrops Fetalis	4.4%
150	Eosinophilia-Myalgia Syndrome	4.3%
151	Chronic granulomatous disease	4.2%
152	Shwartzman Phenomenon	4.2%
153	Hemangioma, Cavernous	4.2%
154	Scurvy	4.1%
155	Purpura Fulminans	4.1%
156	Waterhouse-Friderichsen Syndrome	3.6%
157	POEMS Syndrome	3.3%
158	Kernicterus	2.9%
159	Eosinophilic Granuloma	2.8%
160	Pseudoxanthoma Elasticum	2.1%

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