MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Thrombocythemia, Essential

(UMLS:C0040028)

Definition:: A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.
UMLS ID:: C0040028
MeSH ID:: D013920

Classification:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.378.100.832|C15.378.140.860.800|C15.378.190.636.860.800|C15.378.463.825

Synonym(s)

Thrombocythemia, Essential

ESSENTIAL THROMBOCYTHEMIA

ET - Essential thrombocythaemia

ET - Essential thrombocythemia

Essential (haemorrhagic) thrombocythaemia

Essential (hemorrhagic) thrombocythemia

Essential Thrombocytemia

Essential Thrombocythemia

10.

Essential Thrombocytosis

11.

Essential haemorrhagic thrombocythaemia

12.

Essential hemorrhagic thrombocythemia

13.

Essential thrombocythaemia

14.

Essential thrombocythemia

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Aspirin	View details 11856718 16510297 17137402 18160579	CTD
2	Busulfan	9051142	CTD
3	Clopidogrel	18160579	CTD
4	Hydroxyurea	View details 8638610 8678547 11099330 11736962 12924084 15558807 16440777 16682291 17137402	CTD
5	Imatinib Mesylate	16682291	CTD
6	Melphalan	11099330	CTD
7	Pipobroman	11736962	CTD
8	Thiotepa	7817232	CTD
9	Uracil Mustard	3369437	CTD
10	anagrelide	View details 12924084 15531464 16398570 17137402	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Disseminated Intravascular Coagulation	72.2%
2	Protein S Deficiency	64.7%
3	Thrombasthenia	61.4%
4	Afibrinogenemia	56.2%
5	Factor VII Deficiency	56.2%
6	Factor X Deficiency	56.2%
7	Factor XII Deficiency	56.2%
8	Hemophilia A	56.2%
9	Factor II deficiency	56.2%
10	Factor VIII Deficiency	56.2%
11	Factor V deficiency	56.2%
12	Factor XI Deficiency	56.2%
13	Hypoprothrombinemias	56.2%
14	Vitamin K Deficiency	52.8%
15	Antithrombin III Deficiency	49.9%
16	Protein C Deficiency	49.9%
17	Activated Protein C Resistance	49.7%
18	Polycythemia Vera	44.4%
19	Anemia	42.9%
20	Leukocyte Disorders	42.9%
21	Methemoglobinemia	42.9%
22	Pancytopenia	42.9%
23	Polycythemia	42.9%
24	Sulfhemoglobinemia	42.9%
25	Thrombophilia	42.9%
26	Erythrocytosis	42.9%
27	Bone Marrow Neoplasms	42.8%
28	Leukemoid Reaction	40.7%
29	Thrombocythemia, Essential	40.4%
30	Wiskott-Aldrich Syndrome	39.2%
31	Transfusion Reaction	37%
32	Hypotensive Transfusion Reaction	37%
33	Pregnancy Complications, Hematologic	36.1%
34	Hematologic Neoplasms	36.1%
35	Purpura, Thrombotic Thrombocytopenic	35%
36	Thrombocytopenia	34.4%
37	Hemoglobinuria, Paroxysmal	34.1%
38	Autoimmune thrombocytopenia	33.9%
39	Immune thrombocytopenic purpura	33.9%
40	Bone Marrow Diseases	33.9%
41	MYELODYSPLASTIC SYNDROME	33.1%
42	Blood Platelet Disorders	32.9%
43	Anemia, Diamond-Blackfan	31.4%
44	Blood Coagulation Disorders	30.9%
45	Hemorrhagic Disorders	30.9%
46	Primary Myelofibrosis	30.3%
47	Myelofibrosis	30.3%
48	Myeloid Metaplasia	30.3%
49	bone marrow fibrosis	30.3%
50	Thrombocytosis	30.2%
51	Purpura, Hyperglobulinemic	29.3%
52	Cryoglobulinemia	28.2%
53	Waldenstrom Macroglobulinemia	27.1%
54	Ecchymosis	26.6%
55	Petechiae	26.6%
56	Purpura	26.6%
57	Anemia, Hemolytic	26.6%
58	Anemia, Macrocytic	26.6%
59	Eosinophilia	26.6%
60	Hypoproteinemia	26.6%
61	Leukopenia	26.6%
62	Leukostasis	26.6%
63	Anemia, Sickle Cell	25.8%
64	Thalassemia	25.8%
65	Agammaglobulinemia	25.7%
66	Lymphatic Diseases	25.6%
67	Thrombocytopenic purpura	25.5%
68	Waterhouse-Friderichsen Syndrome	24.1%
69	Thrombotic Microangiopathies	23.8%
70	Monoclonal Gammopathy of Undetermined Significance	23.3%
71	Hemolytic-Uremic Syndrome	23%
72	Multiple Myeloma	22.7%
73	Anemia, Neonatal	22.4%
74	Leukocytosis	22.4%
75	Paraproteinemias	22.4%
76	Pelger-Huet Anomaly	22.4%
77	Pleocytosis	22.4%
78	Infectious Mononucleosis	22.2%
79	Fanconi Anemia	20%
80	Heavy Chain Disease	19.7%
81	Hypergammaglobulinemia	19.4%
82	Sickle Cell Trait	19.4%
83	Transfusion-Related Acute Lung Injury	19.1%
84	Shwartzman Phenomenon	19%
85	Hemangioma, Cavernous	18.9%
86	Atypical Hemolytic Uremic Syndrome	18.9%
87	Hydrops Fetalis	18.8%
88	Scurvy	18.8%
89	Purpura Fulminans	18.8%
90	Leukemia, Myelomonocytic, Chronic	18.7%
91	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	18.7%
92	Leukemia, Myeloid, Chronic-Phase	18.6%
93	Agranulocytosis	18.6%
94	Anemia, Megaloblastic	18.6%
95	Lymphocytosis	18.6%
96	Hypoalbuminemia	18.6%
97	Hypereosinophilic syndrome	18.6%
98	Acute Chest Syndrome	15.8%
99	Lymphopenia	15.7%
100	Job Syndrome	15.5%
101	Neutropenia	14.6%
102	Adenitis	14.3%
103	Histiocytosis	14.3%
104	Lymphadenitis	14.3%
105	Lymphangitis	14.3%
106	Lymphedema	14.3%
107	Splenic Diseases	14.3%
108	Thymus Hyperplasia	14.3%
109	Pseudolymphoma	14.3%
110	Lymphadenopathy	14.3%
111	Eosinophilic Granuloma	13.9%
112	Eosinophilia-Myalgia Syndrome	13.5%
113	Kernicterus	13.4%
114	Chronic granulomatous disease	13.3%
115	Lymphangiectasis, Intestinal	12.7%
116	Febrile Neutropenia	12.6%
117	Pulmonary Eosinophilia	12.4%
118	Eosinophilic Pneumonia	12.4%
119	Pseudoxanthoma Elasticum	12.2%
120	Anemia, Pernicious	12.1%
121	Lymphocele	12%
122	Lymphoproliferative Disorders	12%
123	Lymphatic Abnormalities	12%
124	Thymus Neoplasms	11.9%
125	POEMS Syndrome	11.7%
126	Mucocutaneous Lymph Node Syndrome	10.2%
127	Elephantiasis	8.9%
128	Hypersplenism	8.9%
129	Sarcoidosis	8.9%
130	Elephantiasis Nostras Verrucosa	8.9%
131	Granuloma	7.5%
132	Histiocytic Disorders, Malignant	7.5%
133	Splenic Infarction	7.5%
134	Splenic Neoplasms	7.5%
135	Histiocytosis, Langerhans-Cell	7.4%
136	Tumor Lysis Syndrome	7.4%
137	Sezary Syndrome	7%
138	Splenic Rupture	6.5%
139	Lymphoma	6.4%
140	Thymoma	6.3%
141	Lymphohistiocytosis, Hemophagocytic	6.2%
142	Erdheim-Chester Disease	6.2%
143	Autoimmune Lymphoproliferative Syndrome	5.7%
144	Malignant histiocytosis	5.2%
145	Sarcoidosis, Pulmonary	5.2%
146	Histiocytic sarcoma	5.2%
147	Splenosis	4.4%
148	Hodgkin Disease	4.4%
149	Lymphoma, Non-Hodgkin	4.4%
150	Leukemia, T-Cell	4.4%
151	Leukemia, B-Cell	4.4%
152	Composite Lymphoma	3.9%
153	Lymphangioleiomyomatosis	3.9%
154	Lymphoma, Follicular	3.5%
155	T-Cell Lymphoma	3.5%
156	Mantle cell lymphoma	3.5%
157	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.5%
158	Leukemia, Large Granular Lymphocytic	3.5%
159	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.5%
160	Lymphoma, T-Cell, Cutaneous	3%
161	Lymphoma, AIDS-Related	3%
162	Enteropathy-Associated T-Cell Lymphoma	3%
163	Primary Effusion Lymphoma	3%
164	Mycosis Fungoides	2.8%
165	Lymphomatoid Papulosis	2.8%
166	Plasmablastic lymphoma	2.8%
167	Lymphomatoid Granulomatosis	2.6%
168	Burkitt Lymphoma	2.3%
169	Niemann-Pick Disease, Type C	1.7%

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