MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Blood Coagulation Disorders

(UMLS:C0005779)

Definition:: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.
UMLS ID:: C0005779
MeSH ID:: D001778

Classification:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.378.100

Synonym(s)

Blood Coagulation Disorders

Abnormal;coagulation

Abnormality of the coagulation cascade

BLOOD COAGULATION DISORDER

Blood clotting disorder

Blood clotting disorder, NOS

Blood coagulation disorder

Blood coagulation disorder, NOS

Blood coagulation disorder, disease or syndrome

10.

Blood coagulation disorders

11.

COAGULATION DEFECT

12.

COAGULATION DISORDER

13.

COAGULOPATHY

14.

Clotting disorder

15.

Clotting disorders

16.

Coagulation Defect

17.

Coagulation Disorder

18.

Coagulation defect, unspecified

Associated Drug(s)

	Name	Reference(s)	Data Source
1	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	27224288	CTD
2	Aminocaproic Acid	6537999	CTD
3	Amiodarone	19483382	CTD
4	Aspirin	7960860	CTD
5	Azacitidine	26712470	CTD
6	Baclofen	9033759	CTD
7	Benzbromarone	19483382	CTD
8	Carbamazepine	17923349	CTD
9	Carbenicillin	1036800	CTD
10	Chlorpromazine	3142154	CTD
11	Clofibrate	19483382	CTD
12	Clonazepam	17923349	CTD
13	Deamino Arginine Vasopressin	7960860	CTD
14	Diethylstilbestrol	26712470	CTD
15	Enalapril	16737005	CTD
16	Ethionine	19483382	CTD
17	Fenofibrate	9681093	CTD
18	GDC-0152	22956632	CTD
19	Hydrochloric Acid	15920416	CTD
20	Lamotrigine	17923349	CTD
21	Minocycline	1532250	CTD
22	Mitotane	16822769	CTD
23	Omeprazole	19483382	CTD
24	Penicillin G	62897	CTD
25	Phenobarbital	17923349	CTD
26	Phenprocoumon	20221993	CTD
27	Polychlorinated Dibenzodioxins	12125929	CTD
28	Procainamide	3142154	CTD
29	Propylthiouracil	19483382 20575220	CTD
30	Thioacetamide	19483382	CTD
31	Topiramate	17923349	CTD
32	Tretinoin	15087033 16197459 16206674	CTD
33	Valproic Acid	403429 17923349	CTD
34	Vitamin K	4049235 9681093	CTD
35	Warfarin	View details 4049235 9681093 24733133 26742017	CTD
36	argatroban	11294800 15560992	CTD
37	darexaban	21995444	CTD
38	dehydroacetic acid	17941040	CTD
39	ferrous sulfate	6421970	CTD
40	glycolaldehyde	19397901	CTD
41	pirinixic acid	19483382	CTD
42	reviparin	7167388	CTD
43	sodium arsenite	26712470	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Anemia	42.9%
2	Blood Platelet Disorders	42.9%
3	Bone Marrow Diseases	42.9%
4	Hemorrhagic Disorders	42.9%
5	Leukocyte Disorders	42.9%
6	Methemoglobinemia	42.9%
7	Pancytopenia	42.9%
8	Polycythemia	42.9%
9	Sulfhemoglobinemia	42.9%
10	Thrombophilia	42.9%
11	Erythrocytosis	42.9%
12	Thrombocytosis	37.1%
13	Hemoglobinuria, Paroxysmal	33.3%
14	Leukemoid Reaction	33.3%
15	Anemia, Hemolytic	31%
16	Anemia, Macrocytic	31%
17	Eosinophilia	31%
18	Hypoproteinemia	31%
19	Leukopenia	31%
20	Thrombocytopenia	31%
21	Leukostasis	31%
22	MYELODYSPLASTIC SYNDROME	31%
23	Thrombocythemia, Essential	30.9%
24	Disseminated Intravascular Coagulation	30.5%
25	Protein S Deficiency	30.5%
26	Bone Marrow Neoplasms	30.5%
27	Transfusion Reaction	30%
28	Hypotensive Transfusion Reaction	30%
29	Polycythemia Vera	29.6%
30	Pregnancy Complications, Hematologic	28.6%
31	Hematologic Neoplasms	28.6%
32	Anemia, Diamond-Blackfan	27.6%
33	Primary Myelofibrosis	25.4%
34	Agranulocytosis	25.4%
35	Anemia, Megaloblastic	25.4%
36	Lymphocytosis	25.4%
37	Myelofibrosis	25.4%
38	Myeloid Metaplasia	25.4%
39	Hypoalbuminemia	25.4%
40	Hypereosinophilic syndrome	25.4%
41	bone marrow fibrosis	25.4%
42	Thrombotic Microangiopathies	25.4%
43	Thrombasthenia	24.2%
44	Antithrombin III Deficiency	24.2%
45	Protein C Deficiency	24.2%
46	Lymphatic Diseases	23.1%
47	Neutropenia	22.7%
48	Febrile Neutropenia	21.3%
49	Anemia, Sickle Cell	21.1%
50	Thalassemia	21.1%
51	Anemia, Neonatal	20.9%
52	Leukocytosis	20.9%
53	Paraproteinemias	20.9%
54	Pelger-Huet Anomaly	20.9%
55	Pleocytosis	20.9%
56	Agammaglobulinemia	20.7%
57	Cryoglobulinemia	20%
58	Monoclonal Gammopathy of Undetermined Significance	20%
59	Hemolytic-Uremic Syndrome	18.6%
60	Sickle Cell Trait	18.2%
61	Fanconi Anemia	17.9%
62	Heavy Chain Disease	17.6%
63	Lymphopenia	17.2%
64	Waldenstrom Macroglobulinemia	17.1%
65	Atypical Hemolytic Uremic Syndrome	17%
66	Job Syndrome	16.9%
67	Purpura, Thrombotic Thrombocytopenic	16.7%
68	Leukemia, Myelomonocytic, Chronic	16.7%
69	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	16.7%
70	Infectious Mononucleosis	16.1%
71	Hypergammaglobulinemia	15.8%
72	Pulmonary Eosinophilia	15.4%
73	Eosinophilic Pneumonia	15.4%
74	Transfusion-Related Acute Lung Injury	15.4%
75	Vitamin K Deficiency	15.1%
76	Wiskott-Aldrich Syndrome	15%
77	Leukemia, Myeloid, Chronic-Phase	14.8%
78	Anemia, Pernicious	14.8%
79	Adenitis	14.3%
80	Histiocytosis	14.3%
81	Lymphadenitis	14.3%
82	Lymphangitis	14.3%
83	Lymphedema	14.3%
84	Multiple Myeloma	14.3%
85	Splenic Diseases	14.3%
86	Thymus Hyperplasia	14.3%
87	Pseudolymphoma	14.3%
88	Lymphadenopathy	14.3%
89	Acute Chest Syndrome	13.3%
90	Hydrops Fetalis	13.1%
91	Eosinophilia-Myalgia Syndrome	12.8%
92	Autoimmune thrombocytopenia	12.8%
93	Immune thrombocytopenic purpura	12.8%
94	Chronic granulomatous disease	12.6%
95	Shwartzman Phenomenon	12.6%
96	Hemangioma, Cavernous	12.5%
97	Scurvy	12.4%
98	Afibrinogenemia	12%
99	Factor VII Deficiency	12%
100	Factor X Deficiency	12%
101	Factor XII Deficiency	12%
102	Hemophilia A	12%
103	Activated Protein C Resistance	12%
104	Factor II deficiency	12%
105	Factor VIII Deficiency	12%
106	Factor V deficiency	12%
107	Factor XI Deficiency	12%
108	Hypoprothrombinemias	12%
109	Eosinophilic Granuloma	11.2%
110	Elephantiasis	10.3%
111	Hypersplenism	10.3%
112	Sarcoidosis	10.3%
113	Elephantiasis Nostras Verrucosa	10.3%
114	Lymphangiectasis, Intestinal	10.2%
115	POEMS Syndrome	10%
116	Lymphocele	9.5%
117	Lymphoproliferative Disorders	9.5%
118	Lymphatic Abnormalities	9.5%
119	Thymus Neoplasms	9.3%
120	Kernicterus	8.7%
121	Lymphohistiocytosis, Hemophagocytic	8.5%
122	Erdheim-Chester Disease	8.5%
123	Purpura, Hyperglobulinemic	8.2%
124	Thrombocytopenic purpura	7.6%
125	Granuloma	7%
126	Histiocytic Disorders, Malignant	7%
127	Splenic Infarction	7%
128	Splenic Neoplasms	7%
129	Mucocutaneous Lymph Node Syndrome	6.9%
130	Histiocytosis, Langerhans-Cell	6.8%
131	Tumor Lysis Syndrome	6.8%
132	Pseudoxanthoma Elasticum	6.3%
133	Waterhouse-Friderichsen Syndrome	5.9%
134	Malignant histiocytosis	5.6%
135	Sarcoidosis, Pulmonary	5.6%
136	Histiocytic sarcoma	5.6%
137	Sezary Syndrome	5.5%
138	Splenic Rupture	5.3%
139	Lymphoma	5.2%
140	Thymoma	5%
141	Splenosis	4.2%
142	Hodgkin Disease	4.2%
143	Lymphoma, Non-Hodgkin	4.2%
144	Autoimmune Lymphoproliferative Syndrome	4.2%
145	Leukemia, T-Cell	4.1%
146	Leukemia, B-Cell	4.1%
147	Lymphoma, Follicular	3.7%
148	T-Cell Lymphoma	3.7%
149	Mantle cell lymphoma	3.7%
150	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.7%
151	Leukemia, Large Granular Lymphocytic	3.7%
152	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.7%
153	Lymphoma, T-Cell, Cutaneous	3.5%
154	Lymphoma, AIDS-Related	3.5%
155	Enteropathy-Associated T-Cell Lymphoma	3.5%
156	Primary Effusion Lymphoma	3.5%
157	Mycosis Fungoides	3.3%
158	Lymphomatoid Papulosis	3.3%
159	Plasmablastic lymphoma	3.3%
160	Composite Lymphoma	3.3%
161	Lymphangioleiomyomatosis	3.3%
162	Lymphomatoid Granulomatosis	2.8%
163	Burkitt Lymphoma	2.3%
164	Niemann-Pick Disease, Type C	1.3%

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