MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Pyometra

(UMLS:C0034215)

Definition:: An accumulation of PUS in the uterine cavity (UTERUS). Pyometra generally indicates the presence of infections.
UMLS ID:: C0034215
MeSH ID:: D055112

Classification:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.500.852.544

Synonym(s)

Pyometra

PYOMETRA

Pyometrium

pyometra

pyometrium

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Norgestrel	FAERS: 3		OFFSIDES US FAERS
2	Dimethyl Fumarate	FAERS: 2		US FAERS
3	Omacor	FAERS: 1		US FAERS
4	Rivastigmine	FAERS: 1		US FAERS
5	Alosenn			OFFSIDES
6	Fluorouracil			OFFSIDES
7	Lasofoxifene			SIDER
8	Melengestrol Acetate		12790429	CTD
9	Ribavirin			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Endometrial Hyperplasia	48.4%
2	Endometritis	43.3%
3	Uterine Cervicitis	36%
4	Uterine Inversion	35.9%
5	Endometriosis	34.4%
6	Vaginal Diseases	34.4%
7	Vulvar Diseases	34.4%
8	Endometrioma	34.4%
9	Uterine hemorrhage	32.6%
10	Uterine Prolapse	32.3%
11	Vaginal Prolapse	32.3%
12	Uterine Neoplasms	29%
13	Uterine Cancer	29%
14	Uterine Rupture	27.5%
15	Uterine Cervical Incompetence	26.2%
16	Uterine Perforation	24.3%
17	Metrorrhagia	24.1%
18	Infertility	23.6%
19	Vaginitis	22.6%
20	Vulvitis	22.6%
21	Vaginal Discharge	22.6%
22	Vulvodynia	22.6%
23	Salpingitis	22.3%
24	Vulvovaginitis	22.3%
25	Endometrial Neoplasms	21.5%
26	Menorrhagia	18.2%
27	Urologic Diseases	18.1%
28	Oophoritis	16.9%
29	Leukorrhea	16.8%
30	Parametritis	16.8%
31	Pregnancy Complications	16.4%
32	Vaginal Neoplasms	16.1%
33	Vulvar Neoplasms	16.1%
34	Ovarian Diseases	15.6%
35	Adnexitis	15.2%
36	Pruritus Vulvae	15.2%
37	Vaginal Fistula	15.2%
38	Pelvic Inflammatory Disease	15.2%
39	Sexually Transmitted Diseases	14.9%
40	Candidiasis, Vulvovaginal	14.1%
41	Genital Herpes	14%
42	Urogenital Abnormalities	13.5%
43	Fallopian Tube Neoplasms	13.3%
44	Endometrial Stromal Sarcoma	13%
45	Dyspareunia	11.7%
46	Bacterial Vaginosis	11.6%
47	Trichomonas Vaginitis	11.4%
48	Ovarian Hyperstimulation Syndrome	11.4%
49	Vesicovaginal Fistula	10.4%
50	Urinary Bladder Diseases	10.1%
51	Kidney Diseases	10.1%
52	Ureteral Diseases	10.1%
53	Urethral Diseases	10.1%
54	Urination Disorders	10.1%
55	Urolithiasis	10.1%
56	Genital Neoplasms, Female	9.9%
57	ovarian neoplasm	9.1%
58	Corpus Luteum Cyst	8.7%
59	Ovarian Cysts	8.7%
60	Anovulation	8.5%
61	Polyhydramnios	8.5%
62	Obstetric Labor Complications	8.5%
63	Ectopic Pregnancy	8.5%
64	Pregnancy, Prolonged	8.5%
65	Puerperal Disorders	8.5%
66	Oligohydramnios	8.5%
67	Prenatal Injuries	8.5%
68	Premature Menopause	8.4%
69	Bladder Exstrophy	8.3%
70	Epispadias	8.3%
71	Tuberculosis, Renal	8.2%
72	Anuria	7.8%
73	Ureterolithiasis	7.8%
74	Nephrolithiasis	7.8%
75	Carcinoma, Endometrioid	7.7%
76	Urinary tract infection	7.7%
77	Urologic Neoplasms	7.6%
78	Horseshoe Kidney	7.6%
79	Multicystic Dysplastic Kidney	7.4%
80	Polycystic Ovary Syndrome	7.1%
81	Bladder neck obstruction	6.8%
82	Abruptio Placentae	6.6%
83	Placenta Accreta	6.6%
84	Urinary Bladder Fistula	6.5%
85	Bladder Neoplasm	6.5%
86	Cystitis	6.5%
87	Hydronephrosis	6.5%
88	Hyperoxaluria	6.5%
89	Kidney Cortex Necrosis	6.5%
90	Kidney Neoplasm	6.5%
91	Kidney Papillary Necrosis	6.5%
92	Nephritis	6.5%
93	Nephrosclerosis	6.5%
94	Nephrosis	6.5%
95	Perinephritis	6.5%
96	Kidney Failure	6.5%
97	Uremia	6.5%
98	Ureteral Neoplasms	6.5%
99	Ureteral obstruction	6.5%
100	Ureterocele	6.5%
101	Urethral Neoplasms	6.5%
102	Urethral Obstruction	6.5%
103	Urethritis	6.5%
104	Vesico-Ureteral Reflux	6.5%
105	Urinary Retention	6.5%
106	Oxalosis	6.5%
107	Renal Insufficiency	6.5%
108	Hermaphroditism	6.1%
109	Disorders of Sex Development	6.1%
110	granulosa cell tumor	6.1%
111	Carcinoma, Ovarian Epithelial	6.1%
112	Hypospadias	6%
113	Fetal Diseases	6%
114	Pregnancy Complications, Cardiovascular	6%
115	Pregnancy Complications, Neoplastic	6%
116	Pregnancy Complications, Hematologic	5.7%
117	Pregnancy Complications, Infectious	5.7%
118	Chlamydia Infections	5.7%
119	Gonorrhea	5.7%
120	Fetal Death	5.6%
121	Perinatal death	5.6%
122	Morning Sickness	5.6%
123	Kidney Calculi	5.4%
124	Ureteral Calculi	5.4%
125	Chorioamnionitis	5.3%
126	Pyelocystitis	5.3%
127	Diabetes Insipidus	5%
128	Hepatorenal Syndrome	5%
129	Puerperal Infection	5%
130	Abortion, Habitual	4.9%
131	Bacteriuria	4.9%
132	Diabetic Nephropathy	4.9%
133	Dystocia	4.9%
134	Eclampsia	4.9%
135	Fetal Membranes, Premature Rupture	4.9%
136	Glycosuria	4.9%
137	Hematuria	4.9%
138	Renal hypertension	4.9%
139	Oliguria	4.9%
140	Placental Insufficiency	4.9%
141	Polyuria	4.9%
142	Postpartum Hemorrhage	4.9%
143	Pre-Eclampsia	4.9%
144	Prenatal Exposure Delayed Effects	4.9%
145	Proteinuria	4.9%
146	Pyuria	4.9%
147	Renal Artery Obstruction	4.9%
148	Renal Artery Stenosis	4.9%
149	Urinary Calculi	4.9%
150	HELLP Syndrome	4.9%
151	Placenta, Retained	4.9%
152	Cystocele	4.9%
153	Nephrocalcinosis	4.9%
154	Urinary Incontinence	4.9%
155	Syphilis	4.8%
156	Glomerulonephritis	4.8%
157	Nephritis, Interstitial	4.8%
158	Lipoid nephrosis	4.8%
159	Nephrotic Syndrome	4.8%
160	Pyelitis	4.8%
161	Pyonephrosis	4.8%
162	Urethral Stenosis	4.8%
163	Nephrogenic Diabetes Insipidus	4.8%
164	Congenital Nephrogenic Diabetes Insipidus	4.8%
165	Acute kidney injury	4.8%
166	Urethral stricture	4.8%
167	Pyelonephritis	4.8%
168	Lymphogranuloma Venereum	4.6%
169	Gestational Diabetes	4.2%
170	Mesoblastic Nephroma	4.1%
171	Renal Cell Carcinoma	4.1%
172	Papillary Renal Cell Carcinoma	4.1%
173	Enuresis	4%
174	Balkan Nephropathy	4%
175	Focal glomerulosclerosis	4%
176	Kidney Failure, Chronic	4%
177	Gonadal Dysgenesis	3.9%
178	Adrenogenital Syndrome	3.9%
179	Ovotesticular Disorders of Sex Development	3.9%
180	Azotemia	3.7%
181	Albuminuria	3.6%
182	Glycosuria, Renal	3.6%
183	Hemoglobinuria	3.6%
184	Hypertension, Renovascular	3.6%
185	Urge Incontinence	3.6%
186	Abortion, Veterinary	3.5%
187	Pregnancy Complications, Parasitic	3.5%
188	Lactation Disorder	3.3%
189	Mastitis	3.3%
190	Depression, Postpartum	3.3%
191	Embryo Loss	3.3%
192	Nephroblastoma	3.3%
193	Fetal Resorption	3.3%
194	AIDS-Associated Nephropathy	3.3%
195	Hyperemesis Gravidarum	3.2%
196	Premature Birth	3.2%
197	Hyperandrogenism	3.2%
198	Glomerulonephritis, Membranoproliferative	3.2%
199	Denys-Drash Syndrome	3%
200	Polycystic Kidney Diseases	2.9%
201	Diurnal Enuresis	2.9%
202	Renal Aminoacidurias	2.9%
203	Fanconi Syndrome	2.9%
204	Pseudohypoaldosteronism	2.9%
205	Liddle Syndrome	2.9%
206	Hemolytic-Uremic Syndrome	2.9%
207	Fetal Growth Retardation	2.5%
208	Trophoblastic Neoplasms	2.5%
209	Embolism, Amniotic Fluid	2.5%
210	Fetal Hypoxia	2.5%
211	Fetal Alcohol Spectrum Disorders	2.5%
212	Anti-Glomerular Basement Membrane Disease	2.5%
213	Breech Presentation	2.4%
214	Lupus Nephritis	2.4%
215	Stillbirth	2.4%
216	Renal Osteodystrophy	2.4%
217	Renal rickets	2.4%
218	Renal tubular acidosis	2.4%
219	Polycystic Kidney, Autosomal Dominant	2.4%
220	Cystinuria	2.4%
221	Atypical Hemolytic Uremic Syndrome	2.4%
222	Galactorrhea	2.2%
223	Kallmann Syndrome	2.1%
224	Turner Syndrome	2.1%
225	Hyperphosphaturia	1.8%
226	Klinefelter Syndrome	1.8%
227	Zellweger Syndrome	1.8%
228	Meconium Aspiration Syndrome	1.7%
229	Choriocarcinoma	1.3%
230	Hydatidiform Mole	1.2%
231	Familial Hypophosphatemic Rickets	0.9%
232	Hydrops Fetalis	0.8%

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