MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Placenta Accreta

(UMLS:C0032044)

Definition:: Abnormal placentation in which all or parts of the PLACENTA are attached directly to the MYOMETRIUM due to a complete or partial absence of DECIDUA. It is associated with POSTPARTUM HEMORRHAGE because of the failure of placental separation.
UMLS ID:: C0032044
MeSH ID:: D010921

Classification:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.703.420.643|C13.703.590.609

Synonym(s)

Placenta Accreta

Placenta accreta

Placenta accreta, NOS

accreta placenta

accreta; placenta

placenta accreta

placenta accreta was observed

placenta; accreta

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Norgestrel	FAERS: 31		OFFSIDES US FAERS
2	Medroxyprogesterone Acetate	FAERS: 6		US FAERS
3	17 alpha-Hydroxyprogesterone Caproate	FAERS: 5		US FAERS
4	Dimethyl Fumarate	FAERS: 5		US FAERS
5	Methadone	FAERS: 2		US FAERS
6	Oxytocin	FAERS: 2		OFFSIDES US FAERS
7	Clomiphene	FAERS: 1		US FAERS
8	Medroxyprogesterone	FAERS: 1		US FAERS
9	Methadone	FAERS: 1		US FAERS
10	Methylergonovine	FAERS: 1		US FAERS
11	Misoprostol	FAERS: 1		OFFSIDES US FAERS
12	Nifedipine	FAERS: 1		US FAERS
13	Ondansetron	FAERS: 1		US FAERS
14	Tacrolimus	FAERS: 1		US FAERS
15	Topiramate	FAERS: 1		US FAERS
16	etonogestrel	FAERS: 1		US FAERS
17	tegaserod	FAERS: 1		US FAERS
18	ulipristal acetate	FAERS: 1		US FAERS
19	Cocaine		18622325	CTD
20	Nevirapine			OFFSIDES
21	Tenofovir			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Abruptio Placentae	66.7%
2	Chorioamnionitis	52.5%
3	Dystocia	44.4%
4	Fetal Membranes, Premature Rupture	44.4%
5	Placental Insufficiency	44.4%
6	Placenta, Retained	44.4%
7	Postpartum Hemorrhage	42.4%
8	Polyhydramnios	40.9%
9	Ectopic Pregnancy	40.9%
10	Pregnancy, Prolonged	40.9%
11	Puerperal Disorders	40.9%
12	Oligohydramnios	40.9%
13	Prenatal Injuries	40.9%
14	Uterine Inversion	38%
15	Premature Birth	33%
16	Fetal Diseases	32.1%
17	Pregnancy Complications, Cardiovascular	32.1%
18	Pregnancy Complications, Neoplastic	32.1%
19	Puerperal Infection	32%
20	Pregnancy Complications, Hematologic	31%
21	Pregnancy Complications, Infectious	31%
22	Uterine Rupture	30.9%
23	Fetal Death	30.5%
24	Perinatal death	30.5%
25	Morning Sickness	30.3%
26	Abortion, Habitual	26.7%
27	Eclampsia	26.7%
28	Pre-Eclampsia	26.7%
29	Prenatal Exposure Delayed Effects	26.7%
30	HELLP Syndrome	26.7%
31	Breech Presentation	26.4%
32	Gestational Diabetes	24.5%
33	Female Urogenital Diseases	23.8%
34	Abortion, Veterinary	21.1%
35	Pregnancy Complications, Parasitic	21.1%
36	Obstetric Labor Complications	20.5%
37	Lactation Disorder	20%
38	Mastitis	20%
39	Placenta Accreta	20%
40	Depression, Postpartum	20%
41	Embryo Loss	20%
42	Fetal Resorption	19.8%
43	Hyperemesis Gravidarum	19.8%
44	Uterine Cervical Incompetence	18.8%
45	Fetal Growth Retardation	16.2%
46	Trophoblastic Neoplasms	16.2%
47	Embolism, Amniotic Fluid	16.1%
48	Fetal Hypoxia	16.1%
49	Fetal Alcohol Spectrum Disorders	16.1%
50	Stillbirth	15.7%
51	Galactorrhea	14.8%
52	Meconium Aspiration Syndrome	11.8%
53	Urologic Diseases	10.7%
54	Choriocarcinoma	9.8%
55	Hydatidiform Mole	9.7%
56	Endometritis	9%
57	Endometriosis	8.9%
58	Uterine Diseases	8.9%
59	Vaginal Diseases	8.9%
60	Vulvar Diseases	8.9%
61	Endometrioma	8.9%
62	Urogenital Abnormalities	8.6%
63	Salpingitis	8.1%
64	Vulvovaginitis	8.1%
65	Uterine Neoplasms	7.8%
66	Vaginal Neoplasms	7.8%
67	Vulvar Neoplasms	7.8%
68	Uterine Cancer	7.8%
69	Fallopian Tube Neoplasms	7.2%
70	Vesicovaginal Fistula	6.9%
71	Urinary Bladder Diseases	6.8%
72	Infertility	6.8%
73	Kidney Diseases	6.8%
74	Ureteral Diseases	6.8%
75	Urethral Diseases	6.8%
76	Urination Disorders	6.8%
77	Urolithiasis	6.8%
78	Bladder Exstrophy	6.7%
79	Epispadias	6.7%
80	Genital Neoplasms, Female	6.7%
81	Tuberculosis, Renal	6.6%
82	Hydrops Fetalis	6.6%
83	Anuria	6.6%
84	Endometrial Hyperplasia	6.6%
85	Pyometra	6.6%
86	Ureterolithiasis	6.6%
87	Vaginitis	6.6%
88	Vulvitis	6.6%
89	Vaginal Discharge	6.6%
90	Nephrolithiasis	6.6%
91	Vulvodynia	6.6%
92	Oophoritis	6.5%
93	Endometrial Neoplasms	6.5%
94	Multicystic Dysplastic Kidney	6.2%
95	Bladder neck obstruction	6%
96	Candidiasis, Vulvovaginal	5.9%
97	Urinary Bladder Fistula	5.6%
98	Bladder Neoplasm	5.6%
99	Kidney Neoplasm	5.6%
100	Ureteral Neoplasms	5.6%
101	Urethral Neoplasms	5.6%
102	Carcinoma, Endometrioid	5.6%
103	Urinary tract infection	5.5%
104	Uterine Cervicitis	5.5%
105	Leukorrhea	5.5%
106	Parametritis	5.5%
107	Urologic Neoplasms	5.4%
108	Horseshoe Kidney	5.4%
109	Kidney Calculi	5.4%
110	Ureteral Calculi	5.4%
111	ovarian neoplasm	5.2%
112	Pyelocystitis	5.1%
113	Ovarian Diseases	5%
114	Adnexitis	5%
115	Cystitis	5%
116	Hydronephrosis	5%
117	Hyperoxaluria	5%
118	Kidney Cortex Necrosis	5%
119	Kidney Papillary Necrosis	5%
120	Nephritis	5%
121	Nephrosclerosis	5%
122	Nephrosis	5%
123	Perinephritis	5%
124	Pruritus Vulvae	5%
125	Kidney Failure	5%
126	Uremia	5%
127	Ureteral obstruction	5%
128	Ureterocele	5%
129	Urethral Obstruction	5%
130	Urethritis	5%
131	Uterine hemorrhage	5%
132	Vaginal Fistula	5%
133	Vesico-Ureteral Reflux	5%
134	Urinary Retention	5%
135	Pelvic Inflammatory Disease	5%
136	Oxalosis	5%
137	Renal Insufficiency	5%
138	Uterine Prolapse	4.9%
139	Vaginal Prolapse	4.9%
140	Pyelonephritis	4.8%
141	Sexually Transmitted Diseases	4.7%
142	Endometrial Stromal Sarcoma	4.6%
143	Hermaphroditism	4.5%
144	Disorders of Sex Development	4.5%
145	Hypospadias	4.5%
146	Genital Herpes	4.5%
147	Bacterial Vaginosis	4.2%
148	Trichomonas Vaginitis	4.1%
149	Uterine Perforation	4.1%
150	Ovarian Hyperstimulation Syndrome	4.1%
151	Glomerulonephritis	4.1%
152	Metrorrhagia	4.1%
153	Nephritis, Interstitial	4.1%
154	Lipoid nephrosis	4.1%
155	Nephrotic Syndrome	4.1%
156	Pyelitis	4.1%
157	Pyonephrosis	4.1%
158	Urethral Stenosis	4.1%
159	Nephrogenic Diabetes Insipidus	4.1%
160	Congenital Nephrogenic Diabetes Insipidus	4.1%
161	Acute kidney injury	4.1%
162	Urethral stricture	4.1%
163	Mesoblastic Nephroma	4.1%
164	Renal Cell Carcinoma	4%
165	Papillary Renal Cell Carcinoma	4%
166	Diabetes Insipidus	4%
167	Hepatorenal Syndrome	4%
168	Dyspareunia	4%
169	Bacteriuria	4%
170	Diabetic Nephropathy	4%
171	Glycosuria	4%
172	Hematuria	4%
173	Renal hypertension	4%
174	Oliguria	4%
175	Polyuria	4%
176	Proteinuria	4%
177	Pyuria	4%
178	Renal Artery Obstruction	4%
179	Renal Artery Stenosis	4%
180	Urinary Calculi	4%
181	Cystocele	3.9%
182	Nephrocalcinosis	3.9%
183	Urinary Incontinence	3.9%
184	granulosa cell tumor	3.9%
185	Carcinoma, Ovarian Epithelial	3.9%
186	Balkan Nephropathy	3.7%
187	Focal glomerulosclerosis	3.7%
188	Kidney Failure, Chronic	3.7%
189	Glycosuria, Renal	3.6%
190	Enuresis	3.4%
191	Corpus Luteum Cyst	3.3%
192	Ovarian Cysts	3.3%
193	Azotemia	3.3%
194	Gonadal Dysgenesis	3.3%
195	Adrenogenital Syndrome	3.3%
196	Ovotesticular Disorders of Sex Development	3.3%
197	Nephroblastoma	3.3%
198	Anovulation	3.3%
199	Menorrhagia	3.3%
200	Albuminuria	3.3%
201	Hemoglobinuria	3.3%
202	Hypertension, Renovascular	3.3%
203	Premature Menopause	3.2%
204	Urge Incontinence	3.2%
205	Hyperandrogenism	3.2%
206	Denys-Drash Syndrome	3.2%
207	Glomerulonephritis, Membranoproliferative	3.1%
208	Polycystic Ovary Syndrome	2.9%
209	AIDS-Associated Nephropathy	2.8%
210	Polycystic Kidney Diseases	2.7%
211	Diurnal Enuresis	2.7%
212	Renal Aminoacidurias	2.7%
213	Fanconi Syndrome	2.7%
214	Pseudohypoaldosteronism	2.7%
215	Liddle Syndrome	2.7%
216	Hemolytic-Uremic Syndrome	2.7%
217	Anti-Glomerular Basement Membrane Disease	2.5%
218	Lupus Nephritis	2.5%
219	Polycystic Kidney, Autosomal Dominant	2.4%
220	Cystinuria	2.4%
221	Atypical Hemolytic Uremic Syndrome	2.4%
222	Chlamydia Infections	2.3%
223	Gonorrhea	2.3%
224	Renal tubular acidosis	2.3%
225	Renal Osteodystrophy	2.2%
226	Renal rickets	2.2%
227	Turner Syndrome	2.2%
228	Lymphogranuloma Venereum	2.1%
229	Kallmann Syndrome	2.1%
230	Syphilis	2%
231	Hyperphosphaturia	1.8%
232	Klinefelter Syndrome	1.8%
233	Zellweger Syndrome	1.6%
234	Familial Hypophosphatemic Rickets	1%

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