MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Urolithiasis

(UMLS:C0451641)

Definition:: Formation of stones in any part of the URINARY TRACT, usually in the KIDNEY; URINARY BLADDER; or the URETER.
UMLS ID:: C0451641
MeSH ID:: D052878

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.967

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.967

Synonym(s)

Urolithiasis

UROLITHIASIS

Urinary Stones

Urolithiasis, NOS

urolithiasis

Associated Drug(s)

	Name	Reference(s)	Data Source
1	4-ethylsulfonylnaphthalene-1-sulfonamide	6520738	CTD
2	Acetazolamide	713211 5071712 6520738	CTD
3	Acyclovir	11895069	CTD
4	Amoxicillin	9750621	CTD
5	Ampicillin	14736991	CTD
6	Aripiprazole		SIDER
7	Atazanavir Sulfate	17879904	CTD
8	Ceftriaxone	2904533 7638137 16673364	CTD
9	Choline	16941950	CTD
10	Ethylene Glycol	9471053	CTD
11	Fenofibrate		SIDER
12	Fluoxetine		SIDER
13	Furosemide	6726969	CTD
14	Indinavir	View details 9338724 9767973 11852520 12549631 14991118 17874643 18405026	CTD SIDER
15	Octreotide	2298134	CTD
16	Oxolinic Acid	1480987	CTD
17	Pergolide		SIDER
18	Pregabalin		SIDER
19	Pseudoephedrine	14671078	CTD
20	Sulfadiazine	View details 1340011 1863412 2385768 3400670 8949595 15909603 18701149	CTD
21	Sulfamethoxazole	1448305	CTD
22	Sulfasalazine	10349305 14550462	CTD
23	Sulfinpyrazone	7249646	CTD
24	Teriparatide		SIDER
25	Topiramate	15707510	CTD
26	Triamterene	3946031	CTD
27	Trimethoprim, Sulfamethoxazole Drug Combination	839614 1480987	CTD
28	Uric Acid	20506124	CTD
29	Venlafaxine Hydrochloride		SIDER
30	acetohydroxamic acid	903216	CTD
31	efavirenz	16625385	CTD
32	glycolic acid	9471053	CTD
33	hydrochlorothiazide-triamterene	7248862	CTD
34	muraglitazar	17178691 17426106 17675651	CTD
35	oxamide	6520738	CTD
36	rofecoxib		SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Urinary Bladder Diseases	44.8%
2	Kidney Diseases	44.8%
3	Ureteral Diseases	44.8%
4	Urethral Diseases	44.8%
5	Urination Disorders	44.8%
6	Anuria	43.3%
7	Bladder neck obstruction	39.4%
8	Urinary tract infection	36.1%
9	Pyelocystitis	33.6%
10	Cystitis	32.8%
11	Hydronephrosis	32.8%
12	Hyperoxaluria	32.8%
13	Kidney Cortex Necrosis	32.8%
14	Kidney Papillary Necrosis	32.8%
15	Nephritis	32.8%
16	Nephrosclerosis	32.8%
17	Nephrosis	32.8%
18	Perinephritis	32.8%
19	Kidney Failure	32.8%
20	Uremia	32.8%
21	Ureteral obstruction	32.8%
22	Ureterocele	32.8%
23	Urethral Obstruction	32.8%
24	Urethritis	32.8%
25	Vesico-Ureteral Reflux	32.8%
26	Urinary Retention	32.8%
27	Oxalosis	32.8%
28	Renal Insufficiency	32.8%
29	Pyelonephritis	31.7%
30	Bladder Exstrophy	28.5%
31	Epispadias	28.5%
32	Tuberculosis, Renal	28.2%
33	Glomerulonephritis	27%
34	Nephritis, Interstitial	27%
35	Lipoid nephrosis	27%
36	Nephrotic Syndrome	27%
37	Pyelitis	27%
38	Pyonephrosis	27%
39	Urethral Stenosis	27%
40	Nephrogenic Diabetes Insipidus	27%
41	Congenital Nephrogenic Diabetes Insipidus	27%
42	Acute kidney injury	27%
43	Urethral stricture	27%
44	Diabetes Insipidus	26.5%
45	Hepatorenal Syndrome	26.5%
46	Bacteriuria	26.2%
47	Diabetic Nephropathy	26.2%
48	Glycosuria	26.2%
49	Hematuria	26.2%
50	Renal hypertension	26.2%
51	Oliguria	26.2%
52	Polyuria	26.2%
53	Proteinuria	26.2%
54	Pyuria	26.2%
55	Renal Artery Obstruction	26.2%
56	Renal Artery Stenosis	26.2%
57	Cystocele	26%
58	Nephrocalcinosis	26%
59	Urinary Incontinence	26%
60	Urinary Bladder Fistula	25.6%
61	Bladder Neoplasm	25.6%
62	Kidney Neoplasm	25.6%
63	Ureteral Neoplasms	25.6%
64	Urethral Neoplasms	25.6%
65	Multicystic Dysplastic Kidney	25.2%
66	Balkan Nephropathy	24.1%
67	Focal glomerulosclerosis	24.1%
68	Kidney Failure, Chronic	24.1%
69	Glycosuria, Renal	23.6%
70	Enuresis	22%
71	Azotemia	21.9%
72	Urogenital Abnormalities	21.7%
73	Ureterolithiasis	21.7%
74	Nephrolithiasis	21.7%
75	Albuminuria	21.5%
76	Hemoglobinuria	21.5%
77	Hypertension, Renovascular	21.5%
78	Urge Incontinence	21.4%
79	Glomerulonephritis, Membranoproliferative	20.1%
80	AIDS-Associated Nephropathy	18.4%
81	Mesoblastic Nephroma	18.4%
82	Renal Cell Carcinoma	18.3%
83	Papillary Renal Cell Carcinoma	18.3%
84	Polycystic Kidney Diseases	18%
85	Diurnal Enuresis	17.9%
86	Renal Aminoacidurias	17.8%
87	Fanconi Syndrome	17.8%
88	Pseudohypoaldosteronism	17.8%
89	Liddle Syndrome	17.8%
90	Hemolytic-Uremic Syndrome	17.8%
91	Infertility	17.2%
92	Anti-Glomerular Basement Membrane Disease	16.3%
93	Lupus Nephritis	16.1%
94	Polycystic Kidney, Autosomal Dominant	16%
95	Cystinuria	15.9%
96	Atypical Hemolytic Uremic Syndrome	15.9%
97	Renal tubular acidosis	15.2%
98	Vesicovaginal Fistula	15.1%
99	Nephroblastoma	14.9%
100	Hypospadias	14.8%
101	Genital Diseases, Male	14.6%
102	Renal Osteodystrophy	14.2%
103	Renal rickets	14.2%
104	Urologic Neoplasms	13.7%
105	Horseshoe Kidney	13.7%
106	Endometritis	13.7%
107	Endometriosis	13.6%
108	Uterine Diseases	13.6%
109	Vaginal Diseases	13.6%
110	Vulvar Diseases	13.6%
111	Endometrioma	13.6%
112	Salpingitis	12.4%
113	Vulvovaginitis	12.4%
114	Denys-Drash Syndrome	12.2%
115	Pregnancy Complications	12.2%
116	Uterine Neoplasms	11.9%
117	Vaginal Neoplasms	11.9%
118	Vulvar Neoplasms	11.9%
119	Uterine Cancer	11.9%
120	Sexually Transmitted Diseases	11.9%
121	Hyperphosphaturia	11.8%
122	Kidney Calculi	11.8%
123	Ureteral Calculi	11.8%
124	Hermaphroditism	11.5%
125	Disorders of Sex Development	11.5%
126	Genital Herpes	11.3%
127	Genital Neoplasms, Male	11.1%
128	Uterine Inversion	10.9%
129	Fallopian Tube Neoplasms	10.9%
130	Zellweger Syndrome	10.7%
131	Dyspareunia	10.2%
132	Genital Neoplasms, Female	10.2%
133	Endometrial Hyperplasia	10.1%
134	Pyometra	10.1%
135	Vaginitis	10.1%
136	Vulvitis	10.1%
137	Vaginal Discharge	10.1%
138	Vulvodynia	10.1%
139	Penile Neoplasms	10.1%
140	Prostatic Neoplasms	10.1%
141	Oophoritis	9.9%
142	Endometrial Neoplasms	9.8%
143	Epididymitis	9.3%
144	Penile Diseases	9.3%
145	Prostatic Diseases	9.3%
146	Spermatic Cord Torsion	9.3%
147	Hemospermia	9.3%
148	Testicular Hydrocele	9.3%
149	Candidiasis, Vulvovaginal	8.9%
150	Uterine Rupture	8.8%
151	Uterine Cervical Incompetence	8.7%
152	Carcinoma, Endometrioid	8.5%
153	Uterine Cervicitis	8.4%
154	Leukorrhea	8.4%
155	Parametritis	8.4%
156	Gonadal Dysgenesis	8.3%
157	Adrenogenital Syndrome	8.3%
158	Ovotesticular Disorders of Sex Development	8.3%
159	Prostatic Neoplasms, Castration-Resistant	8.2%
160	Hyperandrogenism	8.1%
161	Cryptorchidism	8%
162	ovarian neoplasm	7.9%
163	Ovarian Diseases	7.7%
164	Adnexitis	7.6%
165	Pruritus Vulvae	7.6%
166	Uterine hemorrhage	7.6%
167	Vaginal Fistula	7.6%
168	Pelvic Inflammatory Disease	7.6%
169	Uterine Prolapse	7.5%
170	Vaginal Prolapse	7.5%
171	Testicular Diseases	7%
172	Varicocele	7%
173	Polyhydramnios	7%
174	Obstetric Labor Complications	7%
175	Ectopic Pregnancy	7%
176	Pregnancy, Prolonged	7%
177	Puerperal Disorders	7%
178	Oligohydramnios	7%
179	Prenatal Injuries	7%
180	Endometrial Stromal Sarcoma	7%
181	Spermatocele	6.9%
182	Balanitis	6.8%
183	Benign prostatic hypertrophy	6.8%
184	Phimosis	6.8%
185	Priapism	6.8%
186	prostatitis	6.8%
187	Prostatic Adenoma	6.8%
188	Benign Prostatic Hyperplasia	6.8%
189	Prostatic Hypertrophy	6.8%
190	Prostatic Hyperplasia	6.8%
191	Abruptio Placentae	6.8%
192	Placenta Accreta	6.8%
193	Familial Hypophosphatemic Rickets	6.7%
194	Bacterial Vaginosis	6.4%
195	Trichomonas Vaginitis	6.3%
196	Uterine Perforation	6.3%
197	Ovarian Hyperstimulation Syndrome	6.3%
198	Metrorrhagia	6.2%
199	Chorioamnionitis	6.2%
200	Chlamydia Infections	5.9%
201	Gonorrhea	5.9%
202	granulosa cell tumor	5.8%
203	Carcinoma, Ovarian Epithelial	5.8%
204	Azoospermia	5.6%
205	Oligospermia	5.6%
206	Impotence, Vasculogenic	5.6%
207	Asthenozoospermia	5.6%
208	Teratozoospermia	5.6%
209	Aspermia	5.6%
210	Fetal Diseases	5.5%
211	Pregnancy Complications, Cardiovascular	5.5%
212	Pregnancy Complications, Neoplastic	5.5%
213	Turner Syndrome	5.4%
214	Puerperal Infection	5.4%
215	Postpartum Hemorrhage	5.4%
216	Pregnancy Complications, Hematologic	5.3%
217	Pregnancy Complications, Infectious	5.3%
218	Lymphogranuloma Venereum	5.2%
219	Kallmann Syndrome	5.2%
220	Fetal Death	5.2%
221	Premature Ejaculation	5.2%
222	Erectile dysfunction	5.2%
223	Perinatal death	5.2%
224	Syphilis	5.1%
225	Morning Sickness	5.1%
226	Corpus Luteum Cyst	5.1%
227	Orchitis	5.1%
228	Ovarian Cysts	5.1%
229	Testicular Neoplasms	5.1%
230	Anovulation	5%
231	Menorrhagia	5%
232	Premature Menopause	4.9%
233	Abortion, Habitual	4.5%
234	Dystocia	4.5%
235	Eclampsia	4.5%
236	Fetal Membranes, Premature Rupture	4.5%
237	Placental Insufficiency	4.5%
238	Pre-Eclampsia	4.5%
239	Prenatal Exposure Delayed Effects	4.5%
240	HELLP Syndrome	4.5%
241	Placenta, Retained	4.5%
242	Klinefelter Syndrome	4.5%
243	Polycystic Ovary Syndrome	4.5%
244	Gestational Diabetes	4.1%
245	Abortion, Veterinary	3.6%
246	Pregnancy Complications, Parasitic	3.6%
247	Lactation Disorder	3.4%
248	Mastitis	3.4%
249	Depression, Postpartum	3.4%
250	Embryo Loss	3.4%
251	Premature Birth	3.4%
252	Fetal Resorption	3.4%
253	Hyperemesis Gravidarum	3.3%
254	Leydig Cell Tumor	3.2%
255	Fetal Growth Retardation	2.7%
256	Trophoblastic Neoplasms	2.7%
257	Embolism, Amniotic Fluid	2.7%
258	Fetal Hypoxia	2.7%
259	Fetal Alcohol Spectrum Disorders	2.7%
260	Breech Presentation	2.7%
261	Stillbirth	2.7%
262	Galactorrhea	2.5%
263	Meconium Aspiration Syndrome	2%
264	Choriocarcinoma	1.7%
265	Hydatidiform Mole	1.6%
266	Hydrops Fetalis	1.1%

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