MetaADEDB 2.0 @ LMMD
Pre-Eclampsia
(UMLS:C0032914)
Definition:
A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
UMLS ID:
C0032914
MeSH ID:
D011225
Classification:
Name:
Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):
C13.703.395.249
Synonym(s)
1.
Pre-Eclampsia
2.
EPH - Edema, proteinuria and hypertension of pregnancy
3.
EPH - Oedema, proteinuria and hypertension of pregnancy
4.
PE - Pre-eclampsia
5.
PET - Pre-eclamptic toxaemia
6.
PET - Pre-eclamptic toxemia
7.
PRE-ECLAMPSIA
8.
PREECLAMPSIA
9.
PREECLAMPSIA/ECLAMPSIA 1
10.
Pre-eclampsia
11.
Pre-eclampsia, NOS
12.
Pre-eclampsia, unspecified
13.
Pre-eclamptic toxaemia, NOS
14.
Pre-eclamptic toxemia
15.
Pre-eclamptic toxemia, NOS
16.
Preeclampsia
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
117 alpha-Hydroxyprogesterone CaproateFAERS: 70US FAERS
2LevetiracetamFAERS: 47US FAERS
3NorgestrelFAERS: 27US FAERS
4FluoxetineFAERS: 23US FAERS
5NuvaRingFAERS: 22US FAERS
6OndansetronFAERS: 17US FAERS
7TacrolimusFAERS: 13
Canada Vigilance: 1		Canada Vigilance
US FAERS
8Dimethyl FumarateFAERS: 11US FAERS
9Venlafaxine HydrochlorideFAERS: 11US FAERS
10Fingolimod HydrochlorideFAERS: 9US FAERS
11AspirinFAERS: 8
Canada Vigilance: 1		Canada Vigilance
US FAERS
12CyclosporineFAERS: 8
Canada Vigilance: 2		Canada Vigilance
US FAERS
13IsotretinoinFAERS: 8US FAERS
14SertralineFAERS: 8US FAERS
154-hydroxybutyric acidFAERS: 7US FAERS
16BuprenorphineFAERS: 7OFFSIDES
US FAERS
17Glatiramer AcetateFAERS: 7US FAERS
18LamotrigineFAERS: 7US FAERS
19ThyroxineFAERS: 7US FAERS
20CitalopramFAERS: 6US FAERS
21OxcarbazepineFAERS: 6US FAERS
22SertralineFAERS: 6US FAERS
23SumatriptanFAERS: 6US FAERS
244-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideFAERS: 5US FAERS
25AripiprazoleFAERS: 5US FAERS
26CabergolineFAERS: 5OFFSIDES
US FAERS
27ClomipramineFAERS: 5US FAERS
28Duloxetine HydrochlorideFAERS: 5US FAERS
29FluoxetineFAERS: 4US FAERS
30GlyburideFAERS: 4US FAERS
31Insulin DetemirFAERS: 4US FAERS
32Medroxyprogesterone AcetateFAERS: 4US FAERS
33MethyldopaFAERS: 4OFFSIDES
US FAERS
34MirtazapineFAERS: 4US FAERS
35NevirapineFAERS: 4OFFSIDES
US FAERS
36NicotineFAERS: 4OFFSIDES
US FAERS
37Ortho EvraFAERS: 4US FAERS
38ParoxetineFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
39Quetiapine FumarateFAERS: 4US FAERS
40RisperidoneFAERS: 4US FAERS
41TenofovirFAERS: 4OFFSIDES
US FAERS
42TopiramateFAERS: 4OFFSIDES
US FAERS
43Valproic AcidFAERS: 4US FAERS
44etonogestrelFAERS: 4US FAERS
45BupivacaineFAERS: 315310446CTD
OFFSIDES
US FAERS
46BuprenorphineFAERS: 3US FAERS
47BuspironeFAERS: 3US FAERS
48CarbamazepineFAERS: 3US FAERS
49CitalopramFAERS: 3US FAERS
50DeferasiroxFAERS: 3US FAERS
51DigoxinFAERS: 3US FAERS
52Imatinib MesylateFAERS: 3US FAERS
53Lurasidone HydrochlorideFAERS: 3US FAERS
54MethylphenidateFAERS: 3US FAERS
55OlanzapineFAERS: 3OFFSIDES
US FAERS
56OrlistatFAERS: 3US FAERS
57ParoxetineFAERS: 3US FAERS
58PrednisoneFAERS: 3US FAERS
59RivaroxabanFAERS: 3US FAERS
60Valproic AcidFAERS: 3US FAERS
61aliskirenFAERS: 3US FAERS
62eltrombopagFAERS: 3US FAERS
63norgestimate, ethinyl estradiol drug combinationFAERS: 3US FAERS
64AcetaminophenFAERS: 2US FAERS
65CapecitabineFAERS: 2US FAERS
66CitalopramFAERS: 2US FAERS
67DocetaxelFAERS: 2US FAERS
68Gadolinium DTPAFAERS: 2US FAERS
69InsulinFAERS: 2US FAERS
70LeflunomideFAERS: 2US FAERS
71LetrozoleFAERS: 2US FAERS
72LoperamideFAERS: 2US FAERS
73OctreotideFAERS: 2US FAERS
74OseltamivirFAERS: 2US FAERS
75PhenytoinFAERS: 22589455
8369243		CTD
US FAERS
76SotalolFAERS: 2US FAERS
77SulindacFAERS: 2US FAERS
78TelbivudineFAERS: 2US FAERS
79TemozolomideFAERS: 2US FAERS
80TinzaparinFAERS: 2US FAERS
81ZidovudineFAERS: 2OFFSIDES
US FAERS
82efavirenzFAERS: 2US FAERS
83teriflunomideFAERS: 2US FAERS
84Atomoxetine HydrochlorideFAERS: 1US FAERS
85BaclofenFAERS: 1US FAERS
86BosentanFAERS: 1US FAERS
87BudesonideFAERS: 1OFFSIDES
US FAERS
88CarboplatinFAERS: 1US FAERS
89CarteololFAERS: 1US FAERS
90CitalopramFAERS: 1US FAERS
91ClozapineFAERS: 1US FAERS
92ColchicineFAERS: 1US FAERS
93CopperFAERS: 1US FAERS
94DarunavirFAERS: 1OFFSIDES
US FAERS
95DeferoxamineFAERS: 1US FAERS
96DiclofenacFAERS: 1US FAERS
97DinoprostoneFAERS: 1US FAERS
98DoxazosinFAERS: 1US FAERS
99Emtricitabine, Rilpivirine, Tenofovir Drug CombinationFAERS: 1US FAERS
100Emtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationFAERS: 1US FAERS
101EnalaprilFAERS: 1US FAERS
102EsomeprazoleFAERS: 1US FAERS
103Ethinyl Estradiol-Norgestrel CombinationFAERS: 1US FAERS
104Ferric Oxide, SaccharatedFAERS: 1US FAERS
105FlecainideFAERS: 1US FAERS
106Fluticasone-Salmeterol Drug CombinationFAERS: 1US FAERS
107FondaparinuxFAERS: 1US FAERS
108HydrochlorothiazideFAERS: 1US FAERS
109HydroxyureaFAERS: 1OFFSIDES
US FAERS
110Insulin degludecFAERS: 1US FAERS
111IrbesartanFAERS: 1US FAERS
112Ketorolac TromethamineFAERS: 1US FAERS
113LCZ 696FAERS: 1US FAERS
114LabetalolFAERS: 11316047
7608802
20006421		CTD
OFFSIDES
US FAERS
115LabetalolFAERS: 1US FAERS
116MebendazoleFAERS: 1US FAERS
117MetforminFAERS: 1US FAERS
118MetforminFAERS: 115910403CTD
US FAERS
119MethotrexateFAERS: 1US FAERS
120MethylphenidateFAERS: 1US FAERS
121MetyraponeFAERS: 1US FAERS
122MisoprostolFAERS: 1OFFSIDES
US FAERS
123ModafinilFAERS: 1US FAERS
124Mycophenolic AcidFAERS: 1US FAERS
125NicardipineFAERS: 1US FAERS
126NifedipineFAERS: 1

View details

1415419
8193107
9197871
11942883
 		CTD
US FAERS
127OseltamivirFAERS: 1US FAERS
128PamidronateFAERS: 1US FAERS
129RamiprilFAERS: 1US FAERS
130RibavirinFAERS: 1US FAERS
131RitodrineFAERS: 1US FAERS
132SirolimusFAERS: 1US FAERS
133Sodium iodide I 131FAERS: 1US FAERS
134SotalolFAERS: 1US FAERS
135SpironolactoneFAERS: 1US FAERS
136SulfasalazineFAERS: 1US FAERS
137SumatriptanFAERS: 1US FAERS
138TenofovirFAERS: 1US FAERS
139TerbinafineFAERS: 1US FAERS
140TerbutalineFAERS: 1US FAERS
141ThyroxineFAERS: 1US FAERS
142TretinoinFAERS: 1US FAERS
143Ursodeoxycholic AcidFAERS: 1US FAERS
144Valproic AcidFAERS: 1US FAERS
145ValsartanFAERS: 1US FAERS
146WarfarinFAERS: 1US FAERS
147betamethasone-17,21-dipropionateFAERS: 1US FAERS
148candesartanFAERS: 1US FAERS
149dienogestFAERS: 1US FAERS
150eltrombopagFAERS: 1US FAERS
151insulin aspart, insulin aspart protamine drug combination 30:70FAERS: 1US FAERS
152insulin glulisineFAERS: 1US FAERS
153ledipasvir, sofosbuvir drug combinationFAERS: 1US FAERS
154lumacaftor, ivacaftor drug combinationFAERS: 1US FAERS
155salmon calcitoninFAERS: 1US FAERS
156salmon calcitoninFAERS: 1US FAERS
157sapropterinFAERS: 1US FAERS
158sibutramineFAERS: 1US FAERS
159tazaroteneFAERS: 1OFFSIDES
US FAERS
16017-alpha-HydroxyprogesteroneSIDER
1618-epi-prostaglandin F2alpha17332518CTD
162AcetazolamideOFFSIDES
163AlbuterolSIDER
164Amlodipine20006421CTD
165AzathioprineOFFSIDES
166BeclomethasoneOFFSIDES
167Betamethasone8193107CTD
168BisacodylOFFSIDES
169Cadmium Compounds27375191CTD
170CarteololOFFSIDES
171CelecoxibOFFSIDES
172CephalexinOFFSIDES
173ChloroquineOFFSIDES
174ClomipramineOFFSIDES
175Clorazepate DipotassiumOFFSIDES
176ClotrimazoleOFFSIDES
177Diethylhexyl Phthalate27177253CTD
178Diethylstilbestrol7823752
17601905		CTD
179Estradiol19903522CTD
180EthosuximideOFFSIDES
181FamciclovirOFFSIDES
182Hydralazine11942883
15804228		CTD
OFFSIDES
183Hydroxylamine20049131CTD
184IbuprofenOFFSIDES
185Iloprost10329876CTD
186IndinavirOFFSIDES
187Isosorbide Dinitrate12164565CTD
188KetamineOFFSIDES
189LansoprazoleOFFSIDES
190LoperamideCanada Vigilance: 1Canada Vigilance
191Lopinavir/RitonavirOFFSIDES
192Magnesium Sulfate

View details

2385256
2589455
3631562
3963084
6112438
7199083
8193107
8300011
8403117
10565464
10755794
12053081
12190013
12357887
12607765
15804228
16021073
16690511
17244984
19561013
20006421
 		CTD
193Malondialdehyde8584011CTD
194MercaptopurineOFFSIDES
195Metoprolol15804228CTD
196MoclobemideOFFSIDES
197Mometasone FuroateOFFSIDES
198NicardipineOFFSIDES
199NitrofurantoinOFFSIDES
200Nitroglycerin17322376CTD
201NortriptylineOFFSIDES
202Oxazepam73027CTD
203Oxygen17442736CTD
204PamidronateOFFSIDES
205Phenobarbital19047607CTD
206Phosphatidylcholines19837457CTD
207Phosphatidylserines19837457CTD
208PindololOFFSIDES
209ProgesteroneOFFSIDES
210Resveratrol22197494CTD
211SaquinavirOFFSIDES
212Sodium CitrateOFFSIDES
213Solifenacin SuccinateOFFSIDES
214SunitinibOFFSIDES
215TerbutalineOFFSIDES
216ThiamineOFFSIDES
217Tiapride HydrochlorideOFFSIDES
218Vitamin B 12OFFSIDES
219Vitamin E8584011CTD
220ZolpidemOFFSIDES
221abacavirOFFSIDES
222alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combinationOFFSIDES
223bisphenol A27177253CTD
224cefpodoxime proxetilOFFSIDES
225cefpodoximeOFFSIDES
226cicaprost10329876CTD
227cilnidipineOFFSIDES
228cyamemazineOFFSIDES
229dexamethasone 21-phosphateOFFSIDES
230dipropylacetamideOFFSIDES
231fosamprenavirOFFSIDES
232lamivudine, zidovudine drug combinationOFFSIDES
233lipoxin A423063943CTD
234lormetazepamOFFSIDES
235monoethyl phthalate27177253CTD
236pinaveriumOFFSIDES
237reviparin19837457CTD
238triuret19219741CTD
239urapidil9829161CTD
Similar ADE(s)
NameSemantic Similarity
1Eclampsia46.7%
2HELLP Syndrome46.7%
3Polyhydramnios31%
4Obstetric Labor Complications31%
5Ectopic Pregnancy31%
6Pregnancy, Prolonged31%
7Puerperal Disorders31%
8Oligohydramnios31%
9Prenatal Injuries31%
10Abruptio Placentae26.7%
11Placenta Accreta26.7%
12Chorioamnionitis22.1%
13Fetal Diseases22%
14Pregnancy Complications, Cardiovascular22%
15Pregnancy Complications, Neoplastic22%
16Pregnancy Complications, Hematologic20.9%
17Pregnancy Complications, Infectious20.9%
18Fetal Death20.5%
19Perinatal death20.5%
20Morning Sickness20.2%
21Abortion, Habitual20%
22Dystocia20%
23Fetal Membranes, Premature Rupture20%
24Placental Insufficiency20%
25Prenatal Exposure Delayed Effects20%
26Puerperal Infection20%
27Placenta, Retained20%
28Postpartum Hemorrhage19.8%
29Female Urogenital Diseases18.5%
30Uterine Inversion16.5%
31Gestational Diabetes15.4%
32Premature Birth14.8%
33Abortion, Veterinary14.3%
34Pregnancy Complications, Parasitic14.3%
35Lactation Disorder13.3%
36Mastitis13.3%
37Depression, Postpartum13.3%
38Embryo Loss13.3%
39Fetal Resorption13.2%
40Hyperemesis Gravidarum13.1%
41Uterine Rupture12.6%
42Uterine Cervical Incompetence12.4%
43Fetal Growth Retardation10.2%
44Trophoblastic Neoplasms10.2%
45Embolism, Amniotic Fluid10.1%
46Fetal Hypoxia10.1%
47Fetal Alcohol Spectrum Disorders10.1%
48Breech Presentation9.9%
49Stillbirth9.8%
50Galactorrhea9.8%
51Urologic Diseases7.3%
52Meconium Aspiration Syndrome6.9%
53Endometriosis6.7%
54Uterine Diseases6.7%
55Vaginal Diseases6.7%
56Vulvar Diseases6.7%
57Endometrioma6.7%
58Hydatidiform Mole6%
59Endometritis5.9%
60Choriocarcinoma5.9%
61Urogenital Abnormalities5.5%
62Salpingitis5.4%
63Vulvovaginitis5.4%
64Endometrial Hyperplasia4.9%
65Pyometra4.9%
66Vaginitis4.9%
67Vulvitis4.9%
68Vaginal Discharge4.9%
69Vulvodynia4.9%
70Uterine Neoplasms4.9%
71Vaginal Neoplasms4.9%
72Vulvar Neoplasms4.9%
73Uterine Cancer4.9%
74Urinary Bladder Diseases4.5%
75Infertility4.5%
76Kidney Diseases4.5%
77Ureteral Diseases4.5%
78Urethral Diseases4.5%
79Urination Disorders4.5%
80Urolithiasis4.5%
81Fallopian Tube Neoplasms4.5%
82Genital Neoplasms, Female4.4%
83Uterine Cervicitis4.1%
84Leukorrhea4.1%
85Oophoritis4.1%
86Parametritis4.1%
87Endometrial Neoplasms4%
88Vesicovaginal Fistula4%
89Anuria3.9%
90Ureterolithiasis3.9%
91Nephrolithiasis3.9%
92Bladder Exstrophy3.9%
93Epispadias3.9%
94Tuberculosis, Renal3.9%
95Hydrops Fetalis3.7%
96Candidiasis, Vulvovaginal3.6%
97Multicystic Dysplastic Kidney3.6%
98Bladder neck obstruction3.6%
99Urinary tract infection3.4%
100Urologic Neoplasms3.4%
101Horseshoe Kidney3.4%
102Ovarian Diseases3.4%
103Adnexitis3.3%
104Cystitis3.3%
105Hydronephrosis3.3%
106Hyperoxaluria3.3%
107Kidney Cortex Necrosis3.3%
108Kidney Papillary Necrosis3.3%
109Nephritis3.3%
110Nephrosclerosis3.3%
111Nephrosis3.3%
112Perinephritis3.3%
113Pruritus Vulvae3.3%
114Kidney Failure3.3%
115Uremia3.3%
116Ureteral obstruction3.3%
117Ureterocele3.3%
118Urethral Obstruction3.3%
119Urethritis3.3%
120Uterine hemorrhage3.3%
121Vaginal Fistula3.3%
122Vesico-Ureteral Reflux3.3%
123Urinary Retention3.3%
124Pelvic Inflammatory Disease3.3%
125Oxalosis3.3%
126Renal Insufficiency3.3%
127Urinary Bladder Fistula3.3%
128Bladder Neoplasm3.3%
129Kidney Neoplasm3.3%
130Ureteral Neoplasms3.3%
131Urethral Neoplasms3.3%
132Uterine Prolapse3.3%
133Vaginal Prolapse3.3%
134Carcinoma, Endometrioid3.2%
135Pyelocystitis3%
136ovarian neoplasm3%
137Kidney Calculi3%
138Ureteral Calculi3%
139Pyelonephritis2.9%
140Sexually Transmitted Diseases2.9%
141Bacterial Vaginosis2.8%
142Hermaphroditism2.7%
143Disorders of Sex Development2.7%
144Endometrial Stromal Sarcoma2.7%
145Trichomonas Vaginitis2.7%
146Uterine Perforation2.7%
147Ovarian Hyperstimulation Syndrome2.7%
148Glomerulonephritis2.7%
149Metrorrhagia2.7%
150Nephritis, Interstitial2.7%
151Lipoid nephrosis2.7%
152Nephrotic Syndrome2.7%
153Pyelitis2.7%
154Pyonephrosis2.7%
155Urethral Stenosis2.7%
156Nephrogenic Diabetes Insipidus2.7%
157Congenital Nephrogenic Diabetes Insipidus2.7%
158Hypospadias2.7%
159Acute kidney injury2.7%
160Urethral stricture2.7%
161Genital Herpes2.7%
162Diabetes Insipidus2.5%
163Hepatorenal Syndrome2.5%
164Dyspareunia2.5%
165Bacteriuria2.5%
166Diabetic Nephropathy2.5%
167Glycosuria2.5%
168Hematuria2.5%
169Renal hypertension2.5%
170Oliguria2.5%
171Polyuria2.5%
172Proteinuria2.5%
173Pyuria2.5%
174Renal Artery Obstruction2.5%
175Renal Artery Stenosis2.5%
176Urinary Calculi2.5%
177Cystocele2.5%
178Nephrocalcinosis2.5%
179Urinary Incontinence2.5%
180Balkan Nephropathy2.4%
181Focal glomerulosclerosis2.4%
182Kidney Failure, Chronic2.4%
183Mesoblastic Nephroma2.3%
184Renal Cell Carcinoma2.3%
185Papillary Renal Cell Carcinoma2.3%
186granulosa cell tumor2.2%
187Carcinoma, Ovarian Epithelial2.2%
188Corpus Luteum Cyst2.1%
189Ovarian Cysts2.1%
190Azotemia2.1%
191Anovulation2%
192Menorrhagia2%
193Albuminuria2%
194Hemoglobinuria2%
195Hypertension, Renovascular2%
196Glycosuria, Renal2%
197Premature Menopause2%
198Urge Incontinence2%
199Enuresis2%
200Gonadal Dysgenesis2%
201Adrenogenital Syndrome2%
202Ovotesticular Disorders of Sex Development2%
203Glomerulonephritis, Membranoproliferative1.9%
204Polycystic Ovary Syndrome1.8%
205Nephroblastoma1.8%
206Hyperandrogenism1.8%
207Denys-Drash Syndrome1.7%
208Polycystic Kidney Diseases1.6%
209AIDS-Associated Nephropathy1.6%
210Diurnal Enuresis1.6%
211Renal Aminoacidurias1.6%
212Fanconi Syndrome1.6%
213Pseudohypoaldosteronism1.6%
214Liddle Syndrome1.6%
215Hemolytic-Uremic Syndrome1.6%
216Anti-Glomerular Basement Membrane Disease1.5%
217Lupus Nephritis1.5%
218Polycystic Kidney, Autosomal Dominant1.4%
219Cystinuria1.4%
220Atypical Hemolytic Uremic Syndrome1.4%
221Chlamydia Infections1.4%
222Gonorrhea1.4%
223Renal tubular acidosis1.3%
224Renal Osteodystrophy1.2%
225Renal rickets1.2%
226Lymphogranuloma Venereum1.2%
227Kallmann Syndrome1.2%
228Syphilis1.2%
229Turner Syndrome1.2%
230Hyperphosphaturia1%
231Klinefelter Syndrome1%
232Zellweger Syndrome0.9%
233Familial Hypophosphatemic Rickets0.6%
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