MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Prenatal Injuries

(UMLS:C0086468)

Definition:: Damages to the EMBRYO, MAMMALIAN or the FETUS before BIRTH. Damages can be caused by any factors including biological, chemical, or physical.
UMLS ID:: C0086468
MeSH ID:: D049188

Classification:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.703.824

Synonym(s)

Prenatal Injuries

Associated Drug(s)

	Name	Reference(s)	Data Source
1	2-ethylhexanoic acid	15901671	CTD
2	25-hydroxyvitamin D	27099250	CTD
3	3,4,5,3',4'-pentachlorobiphenyl	25213558 25711857	CTD
4	Alcohols	View details 8563186 25883026 27112526 27338645 31039417	CTD
5	Amitriptyline	6435276	CTD
6	Aspirin	12072809	CTD
7	Azacitidine	1690922	CTD
8	Baclofen	11532198	CTD
9	Benomyl	19058295	CTD
10	Bicuculline	11532198	CTD
11	Cadmium Chloride	View details 17707671 20213698 23644582 26815315 27417525	CTD
12	Cadmium Compounds	View details 18501191 18956198 20026153 23124188 26125595 29415948	CTD
13	Caffeine	23774253 24239806 25986755	CTD
14	Capsaicin	1378463	CTD
15	Carbamazepine	View details 1932927 10540608 23774253 28267586	CTD
16	Carnitine	16239342	CTD
17	Chir 99021	27216425	CTD
18	Chlordiazepoxide	6435276	CTD
19	Chloroquine	8638253	CTD
20	Cocaine	View details 7945904 9733920 14745934 17622340 18782407	CTD
21	Cortodoxone	23458687	CTD
22	Cyclophosphamide	8312451 8870961 11056294	CTD
23	Dexamethasone	25286332 26283537 30359671	CTD
24	Dibutyl Phthalate	28528174	CTD
25	Diclofenac	24788080	CTD
26	Diethylhexyl Phthalate	25068794	CTD
27	Diethylstilbestrol	22733484	CTD
28	Dimethadione	25446330	CTD
29	Dimethyl Sulfoxide	22169935	CTD
30	Dimethylformamide	22169935	CTD
31	Dipyridamole	25883026	CTD
32	Disulfiram	20045017	CTD
33	EMD 53998	24977338	CTD
34	Enalapril	2829674 7951836	CTD
35	Estradiol	12507662 23557687	CTD
36	Ethylene Glycol	20952502	CTD
37	Fluorouracil	9299594	CTD
38	Folic Acid	View details 16112698 20544798 23787444 24177262	CTD
39	Galantamine	14657522	CTD
40	Gentamicins	16239342	CTD
41	Glucose	24882757	CTD
42	Homocysteine	20544798	CTD
43	Hydroxyurea	25527867	CTD
44	Levetiracetam	25111975	CTD
45	Lidoderm	24323366	CTD
46	Lithium Carbonate	6772020	CTD
47	Lithium	View details 1119612 2062397 3053673 4140306 6518066	CTD
48	Manganese Compounds	26125595	CTD
49	Melatonin	17622340	CTD
50	Mercury Compounds	18501191	CTD
51	Methamphetamine	18633333	CTD
52	Methotrexate	22806879	CTD
53	Methoxychlor	12507662	CTD
54	Methyl Methanesulfonate	22717255	CTD
55	Methylnitrosourea	24594278	CTD
56	Muscimol	11532198	CTD
57	Naled	21788198	CTD
58	Nicotine	24709674 29981921	CTD
59	Nifedipine	24323366	CTD
60	Nimustine	9498910	CTD
61	Omite	21788198	CTD
62	Pantothenic Acid	16112698	CTD
63	Patulin	22847133	CTD
64	Pentachlorophenol	25463847	CTD
65	Phenytoin	23458687 24323366	CTD
66	Polychlorinated Dibenzodioxins	16545771 27284320 29043426	CTD
67	Salicylic Acid	4502305	CTD
68	Silver	25976698	CTD
69	Streptozocin	26887929 27109771	CTD
70	Strychnine	16611622	CTD
71	Thiram	20045017	CTD
72	Tretinoin	23774253	CTD
73	Valproic Acid	View details 1377411 1574164 1574165 1978020 2499680 3080718 3140405 3142446 6126782 6147468 6150384 6401849 6412342 8563186 8935868 10560583 11223853 11339465 12237071 15208813 15901671 16112698 16239295 17049311 23774253	CTD
74	Warfarin	21839171 25094061 25724286	CTD
75	XAV939	25711857	CTD
76	Zinc chloride, anhydrous	21337468	CTD
77	acetochlor	21788198	CTD
78	antimycin	22847133	CTD
79	benz(a)anthracene	23656968	CTD
80	beta-Naphthoflavone	12075112	CTD
81	bisphenol A	View details 22426297 23337607 23557687 23637088 24953688 26283537 28938483	CTD
82	carbamothioic acid, S,S'-(2-(dimethylamino)-1,3-propanediyl) ester	19923012	CTD
83	chlorcyclizine	21058326	CTD
84	chlorpyrifos-ethyl	23637088	CTD
85	clodinafop	21495064	CTD
86	clodinafop-propargyl	21495064	CTD
87	cyazofamid	21788198	CTD
88	cyclopamine	22265815	CTD
89	cyproconazole	22664269	CTD
90	dazomet	21788198	CTD
91	dibenzothiophene	23656968	CTD
92	diniconazole	21788198	CTD
93	dofetilide	24323366	CTD
94	domoic acid	25691335	CTD
95	emamectin benzoate	21788198	CTD
96	etoxazole	21788198	CTD
97	fenoxycarb	21788198	CTD
98	fenpyroximate	21788198	CTD
99	fipronil	16611622	CTD
100	fludioxonil	21788198	CTD
101	fluoxastrobin	21788198	CTD
102	flusilazole	22664269 27094377	CTD
103	fusarenon-X	24983900	CTD
104	kenpaullone	25711857	CTD
105	lactofen	21788198	CTD
106	methyl isothiocyanate	20045017	CTD
107	methyl tert-butyl ether	21684239	CTD
108	methylparaben	23637088	CTD
109	neocuproine	20045017	CTD
110	nickel chloride	21337468	CTD
111	nitrofen	View details 8887094 9498404 22015466 23686664 23780850 23897418 24363088 24488106 25056796 25319798 25487476 27665494	CTD
112	pentachloroanisole	25463847	CTD
113	perfluorooctanoic acid	22273728	CTD
114	pyrene	23656968	CTD
115	sodium arsenite	1523582 23458687	CTD
116	spirodiclofen	21788198	CTD
117	tetrachloroisophthalonitrile	23866729	CTD
118	tetraconazole	21788198	CTD
119	thiazopyr	21788198	CTD
120	thiodicarb	21788198	CTD
121	titanium dioxide	22005274	CTD
122	triadimefon	22664269 26790661	CTD
123	tricaine	16611622	CTD
124	trichostatin A	15901671	CTD
125	triethyl phosphate	24998971	CTD
126	trifloxystrobin	21788198	CTD
127	triphenyltin	24177218	CTD
128	tris(1,3-dichloro-2-propyl)phosphate	24685621	CTD
129	tris(2,3-dibromopropyl)isocyanurate	21961643	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Polyhydramnios	42.9%
2	Obstetric Labor Complications	42.9%
3	Ectopic Pregnancy	42.9%
4	Pregnancy, Prolonged	42.9%
5	Puerperal Disorders	42.9%
6	Oligohydramnios	42.9%
7	Abruptio Placentae	40.9%
8	Placenta Accreta	40.9%
9	Chorioamnionitis	34.7%
10	Abortion, Habitual	31%
11	Dystocia	31%
12	Eclampsia	31%
13	Fetal Membranes, Premature Rupture	31%
14	Placental Insufficiency	31%
15	Pre-Eclampsia	31%
16	HELLP Syndrome	31%
17	Placenta, Retained	31%
18	Puerperal Infection	30.5%
19	Postpartum Hemorrhage	30.3%
20	Fetal Diseases	30%
21	Pregnancy Complications, Cardiovascular	30%
22	Pregnancy Complications, Neoplastic	30%
23	Pregnancy Complications, Hematologic	28.6%
24	Pregnancy Complications, Infectious	28.6%
25	Fetal Death	27.9%
26	Perinatal death	27.9%
27	Morning Sickness	27.6%
28	Uterine Inversion	25.8%
29	Premature Birth	25.4%
30	Female Urogenital Diseases	23.1%
31	Abortion, Veterinary	22%
32	Pregnancy Complications, Parasitic	22%
33	Uterine Cervical Incompetence	21.5%
34	Gestational Diabetes	20.9%
35	Lactation Disorder	20.5%
36	Mastitis	20.5%
37	Depression, Postpartum	20.5%
38	Embryo Loss	20.5%
39	Fetal Resorption	20.2%
40	Hyperemesis Gravidarum	20.1%
41	Uterine Rupture	19.7%
42	Galactorrhea	16.7%
43	Fetal Growth Retardation	15.5%
44	Trophoblastic Neoplasms	15.5%
45	Embolism, Amniotic Fluid	15.4%
46	Fetal Hypoxia	15.4%
47	Fetal Alcohol Spectrum Disorders	15.4%
48	Breech Presentation	15%
49	Stillbirth	14.9%
50	Hydatidiform Mole	11.1%
51	Endometritis	10.5%
52	Meconium Aspiration Syndrome	10.5%
53	Endometriosis	10.3%
54	Uterine Diseases	10.3%
55	Vaginal Diseases	10.3%
56	Vulvar Diseases	10.3%
57	Endometrioma	10.3%
58	Urologic Diseases	10%
59	Choriocarcinoma	9.9%
60	Salpingitis	9.9%
61	Vulvovaginitis	9.9%
62	Endometrial Hyperplasia	8.5%
63	Pyometra	8.5%
64	Vaginitis	8.5%
65	Vulvitis	8.5%
66	Vaginal Discharge	8.5%
67	Vulvodynia	8.5%
68	Uterine Neoplasms	8.3%
69	Vaginal Neoplasms	8.3%
70	Vulvar Neoplasms	8.3%
71	Uterine Cancer	8.3%
72	Fallopian Tube Neoplasms	7.8%
73	Uterine Cervicitis	7.6%
74	Leukorrhea	7.6%
75	Parametritis	7.6%
76	Oophoritis	7.4%
77	Urogenital Abnormalities	7.4%
78	Endometrial Neoplasms	7.3%
79	Vesicovaginal Fistula	7.3%
80	Candidiasis, Vulvovaginal	7%
81	Urinary Bladder Diseases	7%
82	Infertility	7%
83	Kidney Diseases	7%
84	Ureteral Diseases	7%
85	Urethral Diseases	7%
86	Urination Disorders	7%
87	Urolithiasis	7%
88	Genital Neoplasms, Female	6.8%
89	Anuria	6.7%
90	Ureterolithiasis	6.7%
91	Nephrolithiasis	6.7%
92	Bladder neck obstruction	6.3%
93	Hydrops Fetalis	6.2%
94	Bladder Exstrophy	6.2%
95	Epispadias	6.2%
96	Tuberculosis, Renal	6.1%
97	Carcinoma, Endometrioid	6%
98	Multicystic Dysplastic Kidney	5.9%
99	Ovarian Diseases	5.7%
100	Pyelocystitis	5.7%
101	Adnexitis	5.6%
102	Cystitis	5.6%
103	Hydronephrosis	5.6%
104	Hyperoxaluria	5.6%
105	Kidney Cortex Necrosis	5.6%
106	Kidney Papillary Necrosis	5.6%
107	Nephritis	5.6%
108	Nephrosclerosis	5.6%
109	Nephrosis	5.6%
110	Perinephritis	5.6%
111	Pruritus Vulvae	5.6%
112	Kidney Failure	5.6%
113	Uremia	5.6%
114	Ureteral obstruction	5.6%
115	Ureterocele	5.6%
116	Urethral Obstruction	5.6%
117	Urethritis	5.6%
118	Uterine hemorrhage	5.6%
119	Vaginal Fistula	5.6%
120	Vesico-Ureteral Reflux	5.6%
121	Urinary Retention	5.6%
122	Pelvic Inflammatory Disease	5.6%
123	Oxalosis	5.6%
124	Renal Insufficiency	5.6%
125	Uterine Prolapse	5.6%
126	Vaginal Prolapse	5.6%
127	Urinary Bladder Fistula	5.5%
128	Bladder Neoplasm	5.5%
129	Kidney Neoplasm	5.5%
130	Ureteral Neoplasms	5.5%
131	Urethral Neoplasms	5.5%
132	Pyelonephritis	5.5%
133	Kidney Calculi	5.5%
134	Ureteral Calculi	5.5%
135	Endometrial Stromal Sarcoma	5.4%
136	ovarian neoplasm	5.3%
137	Urinary tract infection	5.3%
138	Urologic Neoplasms	5.2%
139	Horseshoe Kidney	5.2%
140	Bacterial Vaginosis	5.1%
141	Trichomonas Vaginitis	5%
142	Uterine Perforation	5%
143	Ovarian Hyperstimulation Syndrome	5%
144	Glomerulonephritis	5%
145	Metrorrhagia	5%
146	Nephritis, Interstitial	5%
147	Lipoid nephrosis	5%
148	Nephrotic Syndrome	5%
149	Pyelitis	5%
150	Pyonephrosis	5%
151	Urethral Stenosis	5%
152	Nephrogenic Diabetes Insipidus	5%
153	Congenital Nephrogenic Diabetes Insipidus	5%
154	Acute kidney injury	5%
155	Urethral stricture	5%
156	Balkan Nephropathy	4.7%
157	Focal glomerulosclerosis	4.7%
158	Kidney Failure, Chronic	4.7%
159	Sexually Transmitted Diseases	4.3%
160	Diabetes Insipidus	4.3%
161	Hepatorenal Syndrome	4.3%
162	Dyspareunia	4.3%
163	Bacteriuria	4.2%
164	Diabetic Nephropathy	4.2%
165	Glycosuria	4.2%
166	Hematuria	4.2%
167	Renal hypertension	4.2%
168	Oliguria	4.2%
169	Polyuria	4.2%
170	Proteinuria	4.2%
171	Pyuria	4.2%
172	Renal Artery Obstruction	4.2%
173	Renal Artery Stenosis	4.2%
174	Urinary Calculi	4.2%
175	Mesoblastic Nephroma	4.2%
176	Renal Cell Carcinoma	4.2%
177	Cystocele	4.2%
178	Hermaphroditism	4.2%
179	Nephrocalcinosis	4.2%
180	Disorders of Sex Development	4.2%
181	Urinary Incontinence	4.2%
182	Papillary Renal Cell Carcinoma	4.2%
183	Hypospadias	4.1%
184	granulosa cell tumor	4.1%
185	Carcinoma, Ovarian Epithelial	4.1%
186	Genital Herpes	4.1%
187	Corpus Luteum Cyst	3.8%
188	Ovarian Cysts	3.8%
189	Azotemia	3.8%
190	Anovulation	3.7%
191	Menorrhagia	3.7%
192	Albuminuria	3.7%
193	Hemoglobinuria	3.7%
194	Hypertension, Renovascular	3.7%
195	Premature Menopause	3.7%
196	Urge Incontinence	3.7%
197	Glomerulonephritis, Membranoproliferative	3.7%
198	Glycosuria, Renal	3.7%
199	Polycystic Ovary Syndrome	3.5%
200	Enuresis	3.4%
201	Gonadal Dysgenesis	3.3%
202	Adrenogenital Syndrome	3.3%
203	Ovotesticular Disorders of Sex Development	3.3%
204	Nephroblastoma	3.3%
205	Hyperandrogenism	3.2%
206	Denys-Drash Syndrome	3.2%
207	Polycystic Kidney Diseases	3%
208	Diurnal Enuresis	3%
209	Renal Aminoacidurias	3%
210	Fanconi Syndrome	3%
211	Pseudohypoaldosteronism	3%
212	Liddle Syndrome	3%
213	Hemolytic-Uremic Syndrome	2.9%
214	Anti-Glomerular Basement Membrane Disease	2.8%
215	Lupus Nephritis	2.8%
216	Polycystic Kidney, Autosomal Dominant	2.8%
217	Cystinuria	2.8%
218	AIDS-Associated Nephropathy	2.8%
219	Atypical Hemolytic Uremic Syndrome	2.8%
220	Chlamydia Infections	2.5%
221	Gonorrhea	2.5%
222	Renal tubular acidosis	2.5%
223	Lymphogranuloma Venereum	2.3%
224	Kallmann Syndrome	2.1%
225	Syphilis	2.1%
226	Turner Syndrome	2.1%
227	Renal Osteodystrophy	2%
228	Renal rickets	2%
229	Hyperphosphaturia	1.8%
230	Klinefelter Syndrome	1.8%
231	Zellweger Syndrome	1.5%
232	Familial Hypophosphatemic Rickets	1%

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