MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Azoospermia

(UMLS:C0004509)

Definition:: A condition of having no sperm present in the ejaculate (SEMEN).
UMLS ID:: C0004509
MeSH ID:: D053713

Classification:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.294.365.700.380

Synonym(s)

Azoospermia

Absent sperm in semen

Azoospermatism

Sperm absent

Sperm absent - azoospermia

Spermatozoa absent

azoospermia

azospermia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Finasteride	FAERS: 27 Canada Vigilance: 1		Canada Vigilance US FAERS
2	Citalopram	FAERS: 19		US FAERS
3	Testosterone	FAERS: 18		SIDER US FAERS
4	Carbamazepine	FAERS: 8		US FAERS
5	Valproic Acid	FAERS: 7		US FAERS
6	Hydroxyurea	FAERS: 6		OFFSIDES SIDER US FAERS
7	Isotretinoin	FAERS: 6		US FAERS
8	Valproic Acid	FAERS: 6		US FAERS
9	Imatinib Mesylate	FAERS: 5		US FAERS
10	Aripiprazole	FAERS: 4		US FAERS
11	Azithromycin	FAERS: 4		US FAERS
12	Clozapine	FAERS: 4		US FAERS
13	Itraconazole	FAERS: 3		US FAERS
14	Rosuvastatin Calcium	FAERS: 3		US FAERS
15	Sirolimus	FAERS: 3		OFFSIDES SIDER US FAERS
16	Cyclosporine	FAERS: 2		US FAERS
17	Everolimus	FAERS: 2		US FAERS
18	Imatinib Mesylate	FAERS: 2		US FAERS
19	Levetiracetam	FAERS: 2		US FAERS
20	Melphalan	FAERS: 2		US FAERS
21	Risperidone	FAERS: 2		US FAERS
22	Rosuvastatin Calcium	FAERS: 2		US FAERS
23	Acarbose	FAERS: 1		US FAERS
24	Acitretin	FAERS: 1		US FAERS
25	Anastrozole	FAERS: 1		US FAERS
26	Atomoxetine Hydrochloride	FAERS: 1		US FAERS
27	Buprenorphine	FAERS: 1		US FAERS
28	Cyclophosphamide	FAERS: 1	View details 1249681 6788612 9166702 16207182	CTD SIDER US FAERS
29	Duloxetine Hydrochloride	FAERS: 1		US FAERS
30	Dutasteride	FAERS: 1		US FAERS
31	Famciclovir	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
32	Hydromorphone	FAERS: 1		US FAERS
33	Lacosamide	FAERS: 1		US FAERS
34	Lamotrigine	FAERS: 1		US FAERS
35	Lenalidomide	FAERS: 1		US FAERS
36	Loperamide	FAERS: 1		US FAERS
37	Methotrexate	FAERS: 1		SIDER US FAERS
38	Omeprazole	FAERS: 1		US FAERS
39	Paliperidone Palmitate	FAERS: 1		US FAERS
40	Pravastatin	FAERS: 1		US FAERS
41	Pseudoephedrine	FAERS: 1		US FAERS
42	Sitagliptin Phosphate	FAERS: 1		OFFSIDES US FAERS
43	Spironolactone	FAERS: 1		US FAERS
44	Tacrolimus	FAERS: 1		US FAERS
45	Tamsulosin	FAERS: 1		US FAERS
46	Terbinafine	FAERS: 1		US FAERS
47	Valproic Acid	FAERS: 1		US FAERS
48	Varenicline	FAERS: 1		US FAERS
49	silodosin	FAERS: 1		US FAERS
50	testosterone undecanoate	FAERS: 1		US FAERS
51	1,2-dibromo-3-chloropropane		73955	CTD
52	2-ethoxyethanol		6492198 6499807	CTD
53	ABVD protocol		17965791	CTD
54	Bleomycin			OFFSIDES
55	Bosentan			SIDER
56	Cadmium Compounds		27289041	CTD
57	Colchicine			SIDER
58	Cyproterone			SIDER
59	Cytarabine			OFFSIDES
60	Daunorubicin			OFFSIDES
61	Dexamethasone		16207182	CTD
62	Doxorubicin			SIDER
63	Etoposide			OFFSIDES
64	Flecainide			OFFSIDES
65	Fluoxetine			SIDER
66	Fluoxymesterone			SIDER
67	Gatifloxacin			OFFSIDES
68	Ifosfamide			OFFSIDES SIDER
69	Ketoconazole			SIDER
70	Mercaptopurine			OFFSIDES SIDER
71	Mesalamine			SIDER
72	Methyltestosterone			SIDER
73	Mitoxantrone			OFFSIDES
74	Moxifloxacin			OFFSIDES
75	Nandrolone			SIDER
76	Nitrogen			SIDER
77	Oxandrolone			SIDER
78	Oxymetholone			SIDER
79	Paroxetine			SIDER
80	Procarbazine			OFFSIDES SIDER
81	Ribavirin			OFFSIDES
82	Sulfasalazine			SIDER
83	Thiotepa			SIDER
84	Vinblastine			OFFSIDES
85	gemcitabine			SIDER
86	trestolone acetate		14602755	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Oligospermia	48.4%
2	Asthenozoospermia	48.4%
3	Teratozoospermia	48.4%
4	Aspermia	48.4%
5	Epididymitis	25.4%
6	Penile Diseases	25.4%
7	Prostatic Diseases	25.4%
8	Spermatic Cord Torsion	25.4%
9	Hemospermia	25.4%
10	Testicular Hydrocele	25.4%
11	Testicular Diseases	17.2%
12	Varicocele	17.2%
13	Genital Neoplasms, Male	17.1%
14	Spermatocele	16.9%
15	Balanitis	14.8%
16	Benign prostatic hypertrophy	14.8%
17	Phimosis	14.8%
18	Priapism	14.8%
19	prostatitis	14.8%
20	Prostatic Adenoma	14.8%
21	Benign Prostatic Hyperplasia	14.8%
22	Prostatic Hypertrophy	14.8%
23	Prostatic Hyperplasia	14.8%
24	Penile Neoplasms	13.8%
25	Prostatic Neoplasms	13.8%
26	Urologic Diseases	10.8%
27	Sexually Transmitted Diseases	10.6%
28	Premature Ejaculation	10.1%
29	Erectile dysfunction	10.1%
30	Genital Herpes	10%
31	Orchitis	9.9%
32	Impotence, Vasculogenic	9.7%
33	Cryptorchidism	9.4%
34	Hypospadias	9.4%
35	Prostatic Neoplasms, Castration-Resistant	9%
36	Urogenital Abnormalities	8.1%
37	Dyspareunia	7.5%
38	Testicular Neoplasms	5.7%
39	Urinary Bladder Diseases	5.6%
40	Kidney Diseases	5.6%
41	Ureteral Diseases	5.6%
42	Urethral Diseases	5.6%
43	Urination Disorders	5.6%
44	Urolithiasis	5.6%
45	Bladder Exstrophy	4.4%
46	Epispadias	4.4%
47	Tuberculosis, Renal	4.4%
48	Urinary tract infection	4.3%
49	Urologic Neoplasms	4.2%
50	Horseshoe Kidney	4.2%
51	Anuria	3.9%
52	Ureterolithiasis	3.9%
53	Nephrolithiasis	3.9%
54	Multicystic Dysplastic Kidney	3.9%
55	Hermaphroditism	3.4%
56	Disorders of Sex Development	3.4%
57	Urinary Bladder Fistula	3.3%
58	Bladder Neoplasm	3.3%
59	Cystitis	3.3%
60	Hydronephrosis	3.3%
61	Hyperoxaluria	3.3%
62	Kidney Cortex Necrosis	3.3%
63	Kidney Neoplasm	3.3%
64	Kidney Papillary Necrosis	3.3%
65	Nephritis	3.3%
66	Nephrosclerosis	3.3%
67	Nephrosis	3.3%
68	Perinephritis	3.3%
69	Kidney Failure	3.3%
70	Uremia	3.3%
71	Ureteral Neoplasms	3.3%
72	Ureteral obstruction	3.3%
73	Ureterocele	3.3%
74	Urethral Neoplasms	3.3%
75	Urethral Obstruction	3.3%
76	Urethritis	3.3%
77	Vesico-Ureteral Reflux	3.3%
78	Urinary Retention	3.3%
79	Oxalosis	3.3%
80	Renal Insufficiency	3.3%
81	Bladder neck obstruction	3.2%
82	Chlamydia Infections	3.2%
83	Gonorrhea	3.2%
84	Syphilis	2.8%
85	Diabetes Insipidus	2.5%
86	Hepatorenal Syndrome	2.5%
87	Bacteriuria	2.5%
88	Diabetic Nephropathy	2.5%
89	Glycosuria	2.5%
90	Hematuria	2.5%
91	Renal hypertension	2.5%
92	Oliguria	2.5%
93	Polyuria	2.5%
94	Proteinuria	2.5%
95	Pyuria	2.5%
96	Renal Artery Obstruction	2.5%
97	Renal Artery Stenosis	2.5%
98	Urinary Calculi	2.5%
99	Cystocele	2.4%
100	Nephrocalcinosis	2.4%
101	Urinary Incontinence	2.4%
102	Kidney Calculi	2.4%
103	Ureteral Calculi	2.4%
104	Lymphogranuloma Venereum	2.4%
105	Leydig Cell Tumor	2.4%
106	Pyelocystitis	2.2%
107	Glomerulonephritis	2.1%
108	Nephritis, Interstitial	2.1%
109	Lipoid nephrosis	2.1%
110	Nephrotic Syndrome	2.1%
111	Pyelitis	2.1%
112	Pyonephrosis	2.1%
113	Urethral Stenosis	2.1%
114	Nephrogenic Diabetes Insipidus	2.1%
115	Congenital Nephrogenic Diabetes Insipidus	2.1%
116	Acute kidney injury	2.1%
117	Urethral stricture	2.1%
118	Enuresis	2%
119	Gonadal Dysgenesis	2%
120	Adrenogenital Syndrome	2%
121	Ovotesticular Disorders of Sex Development	2%
122	Pyelonephritis	1.9%
123	Mesoblastic Nephroma	1.8%
124	Renal Cell Carcinoma	1.8%
125	Papillary Renal Cell Carcinoma	1.8%
126	Azotemia	1.6%
127	AIDS-Associated Nephropathy	1.6%
128	Albuminuria	1.6%
129	Glycosuria, Renal	1.6%
130	Hemoglobinuria	1.6%
131	Hypertension, Renovascular	1.6%
132	Urge Incontinence	1.6%
133	Balkan Nephropathy	1.6%
134	Focal glomerulosclerosis	1.6%
135	Kidney Failure, Chronic	1.6%
136	Nephroblastoma	1.5%
137	Hyperandrogenism	1.4%
138	Polycystic Kidney Diseases	1.3%
139	Diurnal Enuresis	1.3%
140	Renal Aminoacidurias	1.3%
141	Fanconi Syndrome	1.3%
142	Pseudohypoaldosteronism	1.3%
143	Liddle Syndrome	1.3%
144	Hemolytic-Uremic Syndrome	1.3%
145	Glomerulonephritis, Membranoproliferative	1.3%
146	Denys-Drash Syndrome	1.2%
147	Renal Osteodystrophy	1.2%
148	Renal rickets	1.2%
149	Renal tubular acidosis	1.1%
150	Anti-Glomerular Basement Membrane Disease	1%
151	Lupus Nephritis	1%
152	Polycystic Kidney, Autosomal Dominant	1%
153	Cystinuria	1%
154	Atypical Hemolytic Uremic Syndrome	1%
155	Kallmann Syndrome	0.9%
156	Turner Syndrome	0.9%
157	Zellweger Syndrome	0.9%
158	Hyperphosphaturia	0.8%
159	Klinefelter Syndrome	0.8%
160	Familial Hypophosphatemic Rickets	0.4%

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