MetaADEDB 2.0 @ LMMD
Infertility
(UMLS:C0021359)
Definition:
A reduced or absent capacity to reproduce.
UMLS ID:
C0021359
MeSH ID:
D007246
Classification 1:
Name:
Male Urogenital Diseases
MeSH Tree Number(s):
C12.294.365
Classification 2:
Name:
Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):
C13.351.500.365
Synonym(s)
1.
Infertility
2.
Cannot achieve a pregnancy
3.
Difficulty conceiving
4.
INFERTILITY
5.
Infertile
6.
Infertility, NOS
7.
Not fertile
8.
Sterility
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1NorgestrelFAERS: 83US FAERS
2Medroxyprogesterone AcetateFAERS: 61
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
3FinasterideFAERS: 48US FAERS
4etonogestrelFAERS: 33US FAERS
5RisperidoneFAERS: 26US FAERS
6IsotretinoinFAERS: 23US FAERS
7CitalopramFAERS: 15US FAERS
8TestosteroneFAERS: 15US FAERS
9Ortho EvraFAERS: 13US FAERS
10CopperFAERS: 9US FAERS
11Imatinib MesylateFAERS: 831278918CTD
US FAERS
12LamotrigineFAERS: 8US FAERS
13NuvaRingFAERS: 7US FAERS
14CarbamazepineFAERS: 6US FAERS
15DiclofenacFAERS: 6US FAERS
16AripiprazoleFAERS: 5US FAERS
17ThyroxineFAERS: 5US FAERS
18ziprasidoneFAERS: 5US FAERS
19MethylphenidateFAERS: 4US FAERS
20Valproic AcidFAERS: 4US FAERS
21Valproic AcidFAERS: 4US FAERS
22AmlodipineFAERS: 3US FAERS
23AtorvastatinFAERS: 3US FAERS
24ClozapineFAERS: 3US FAERS
25Dimethyl FumarateFAERS: 3
Canada Vigilance: 2		Canada Vigilance
US FAERS
26IbuprofenFAERS: 3US FAERS
27ItraconazoleFAERS: 3US FAERS
28MesalamineFAERS: 3SIDER
US FAERS
29Mycophenolic AcidFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
30OlanzapineFAERS: 3US FAERS
31ParoxetineFAERS: 3US FAERS
32Probenecid and colchicineFAERS: 3US FAERS
33Quetiapine FumarateFAERS: 3OFFSIDES
US FAERS
34SertralineFAERS: 3US FAERS
35entecavirFAERS: 3US FAERS
362-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chlorideFAERS: 2OFFSIDES
US FAERS
37BuprenorphineFAERS: 2US FAERS
38CelecoxibFAERS: 2US FAERS
39CitalopramFAERS: 2US FAERS
40DesogestrelFAERS: 2US FAERS
41Fingolimod HydrochlorideFAERS: 2US FAERS
42GabapentinFAERS: 2US FAERS
43HaloperidolFAERS: 2US FAERS
44HydroxyureaFAERS: 2US FAERS
45LamivudineFAERS: 2US FAERS
46MethotrexateFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
47MinoxidilFAERS: 2US FAERS
48NicotineFAERS: 220363831CTD
US FAERS
49OfloxacinFAERS: 2US FAERS
50PregabalinFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
51PromethazineFAERS: 2US FAERS
52RivaroxabanFAERS: 2US FAERS
53Rosuvastatin CalciumFAERS: 2US FAERS
54SumatriptanFAERS: 2US FAERS
55TerbinafineFAERS: 2OFFSIDES
US FAERS
56ThalidomideFAERS: 2US FAERS
57TopiramateFAERS: 2US FAERS
58ValsartanFAERS: 2US FAERS
59Venlafaxine HydrochlorideFAERS: 2US FAERS
60nefazodoneFAERS: 2US FAERS
61norgestimate, ethinyl estradiol drug combinationFAERS: 2US FAERS
62rofecoxibFAERS: 2US FAERS
63teriflunomideFAERS: 2US FAERS
6417 alpha-Hydroxyprogesterone CaproateFAERS: 1US FAERS
654-hydroxybutyric acidFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
664-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideFAERS: 1US FAERS
67AcitretinFAERS: 1US FAERS
68AnastrozoleFAERS: 1US FAERS
69ArthrotecFAERS: 1US FAERS
70Binedaline hydrochlorideFAERS: 1US FAERS
71BortezomibFAERS: 1SIDER
US FAERS
72BudesonideFAERS: 1US FAERS
73CalcitriolFAERS: 1US FAERS
74CetirizineFAERS: 1US FAERS
75CitalopramFAERS: 1US FAERS
76CyclosporineFAERS: 1US FAERS
77DexamethasoneFAERS: 1US FAERS
78Duloxetine HydrochlorideFAERS: 1US FAERS
79EverolimusFAERS: 1US FAERS
80FlurbiprofenFAERS: 1US FAERS
81GefitinibFAERS: 1US FAERS
82Glatiramer AcetateFAERS: 1US FAERS
83Imatinib MesylateFAERS: 1US FAERS
84ImipramineFAERS: 1US FAERS
85IrbesartanFAERS: 1US FAERS
86IvabradineFAERS: 1US FAERS
87LenalidomideFAERS: 1US FAERS
88LeuprolideFAERS: 1US FAERS
89LisinoprilFAERS: 1US FAERS
90MethadoneFAERS: 1US FAERS
91MethotrexateFAERS: 1US FAERS
92ModafinilFAERS: 1US FAERS
93ModafinilFAERS: 1US FAERS
94NaproxenFAERS: 1SIDER
US FAERS
95OmeprazoleFAERS: 1US FAERS
96OxcarbazepineFAERS: 1US FAERS
97PravastatinFAERS: 1US FAERS
98ProgesteroneFAERS: 1SIDER
US FAERS
99PromethazineFAERS: 1US FAERS
100QlairaFAERS: 1US FAERS
101RanitidineFAERS: 1US FAERS
102SertralineFAERS: 1US FAERS
103Sildenafil CitrateFAERS: 1US FAERS
104SotalolFAERS: 1US FAERS
105SulfasalazineFAERS: 1SIDER
US FAERS
106TacrolimusFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
107Thiothixene dihydrochloride dihydrateFAERS: 1US FAERS
108ThiothixeneFAERS: 1US FAERS
109ThyroxineFAERS: 1SIDER
US FAERS
110VerapamilFAERS: 1US FAERS
111Vilazodone HydrochlorideFAERS: 1US FAERS
112darifenacinFAERS: 1US FAERS
113eletriptanFAERS: 1US FAERS
114halobetasolFAERS: 1US FAERS
115haloperidol decanoateFAERS: 1US FAERS
116hydrocortisone acetateFAERS: 1US FAERS
117sibutramineFAERS: 1US FAERS
118testosterone undecanoateFAERS: 1US FAERS
119zolmitriptanFAERS: 1US FAERS
1201-bromopropane17517825CTD
1212,2-bis(bromomethyl)-1,3-propanediol2792593CTD
1222-(thiocyanomethylthio)benzothiazole30763314CTD
12325-hydroxyvitamin D28655646CTD
124AllopurinolSIDER
125AmoxicillinOFFSIDES
126BeclomethasoneOFFSIDES
127BusulfanSIDER
128Caffeine mixture with phenobarbitalOFFSIDES
129CefadroxilSIDER
130ChlorambucilSIDER
131Chlorpromazine31369748CTD
132CisaprideOFFSIDES
133ClomipheneOFFSIDES
134CyclophosphamideSIDER
135CyproteroneSIDER
136DesoximetasoneOFFSIDES
137Diatomaceous Earth31369748CTD
138Dibutyl Phthalate30763314CTD
139Diethylstilbestrol15036965CTD
140EpinephrineOFFSIDES
141EplerenoneOFFSIDES
142EsomeprazoleCanada Vigilance: 1Canada Vigilance
143EtoposideOFFSIDES
144FlecainideOFFSIDES
145FosinoprilOFFSIDES
146GanciclovirSIDER
147GatifloxacinOFFSIDES
148GlutamineOFFSIDES
149HydrocortisoneOFFSIDES
150IfosfamideSIDER
151Iodide ionSIDER
152KetorolacSIDER
153MedroxyprogesteroneOFFSIDES
154MelphalanSIDER
155MeperidineOFFSIDES
156Mercuric Chloride21843797CTD
157MetolazoneOFFSIDES
158MilrinoneOFFSIDES
159MitoxantroneSIDER
160NorepinephrineOFFSIDES
161NorethindroneSIDER
162Paraquat21843797CTD
163Permethrin30763314CTD
164ProcarbazineSIDER
165RibavirinOFFSIDES
166SRI-51117882CTD
167SotalolOFFSIDES
168SumatriptanOFFSIDES
169TemozolomideSIDER
170Thiram6420938CTD
171TretinoinOFFSIDES
172Uranium21262344CTD
173Vitamin E21843797CTD
174Zearalenone23707492CTD
175Ziram6420938CTD
176bisphenol A21059909
27120497		CTD
177chlorpyrifos-ethyl22180373CTD
178chromium hexavalent ion21621607CTD
179cypermethrin19862501CTD
180decamethrin28119079CTD
181ferbam6420938CTD
182mancozeb22369882CTD
183mono-benzyl phthalate22197707CTD
184monobutyl phthalate22197707CTD
185monoethyl phthalate22197707CTD
186sibutramineOFFSIDES
187triphenyltin15205045CTD
Similar ADE(s)
NameSemantic Similarity
1Endometritis32%
2Endometriosis31.8%
3Uterine Diseases31.8%
4Vaginal Diseases31.8%
5Vulvar Diseases31.8%
6Endometrioma31.8%
7Sexually Transmitted Diseases31%
8Genital Herpes29.4%
9Salpingitis28.9%
10Vulvovaginitis28.9%
11Epididymitis27.9%
12Penile Diseases27.9%
13Prostatic Diseases27.9%
14Spermatic Cord Torsion27.9%
15Hemospermia27.9%
16Testicular Hydrocele27.9%
17Urologic Diseases27.3%
18Dyspareunia26.5%
19Endometrial Hyperplasia23.6%
20Pyometra23.6%
21Vaginitis23.6%
22Vulvitis23.6%
23Vaginal Discharge23.6%
24Vulvodynia23.6%
25Penile Neoplasms23.5%
26Prostatic Neoplasms23.5%
27Oophoritis23.2%
28Genital Neoplasms, Male22.2%
29Urogenital Abnormalities21.7%
30Hypospadias21.6%
31Testicular Diseases21.1%
32Varicocele21.1%
33Uterine Inversion21%
34Candidiasis, Vulvovaginal20.8%
35Spermatocele20.7%
36Balanitis20.5%
37Benign prostatic hypertrophy20.5%
38Phimosis20.5%
39Priapism20.5%
40prostatitis20.5%
41Prostatic Adenoma20.5%
42Benign Prostatic Hyperplasia20.5%
43Prostatic Hypertrophy20.5%
44Prostatic Hyperplasia20.5%
45Uterine Neoplasms19.9%
46Vaginal Neoplasms19.9%
47Vulvar Neoplasms19.9%
48Uterine Cancer19.9%
49Uterine Cervicitis19.6%
50Leukorrhea19.6%
51Parametritis19.6%
52Prostatic Neoplasms, Castration-Resistant19.2%
53Ovarian Diseases17.9%
54Adnexitis17.6%
55Pruritus Vulvae17.6%
56Uterine hemorrhage17.6%
57Vaginal Fistula17.6%
58Pelvic Inflammatory Disease17.6%
59Uterine Prolapse17.5%
60Vaginal Prolapse17.5%
61Fallopian Tube Neoplasms17.5%
62Urinary Bladder Diseases17.2%
63Kidney Diseases17.2%
64Ureteral Diseases17.2%
65Urethral Diseases17.2%
66Urination Disorders17.2%
67Urolithiasis17.2%
68Uterine Cervical Incompetence17%
69Uterine Rupture17%
70Bladder Exstrophy16.9%
71Epispadias16.9%
72Impotence, Vasculogenic16.9%
73Tuberculosis, Renal16.8%
74Anuria16.7%
75Ureterolithiasis16.7%
76Nephrolithiasis16.7%
77Endometrial Neoplasms16.4%
78Multicystic Dysplastic Kidney15.6%
79Premature Ejaculation15.5%
80Erectile dysfunction15.5%
81Chlamydia Infections15.3%
82Gonorrhea15.3%
83Orchitis15.3%
84Bladder neck obstruction15.2%
85Vesicovaginal Fistula15.1%
86Bacterial Vaginosis14.9%
87Cryptorchidism14.8%
88Trichomonas Vaginitis14.6%
89Uterine Perforation14.6%
90Ovarian Hyperstimulation Syndrome14.6%
91Metrorrhagia14.5%
92Urinary Bladder Fistula14.2%
93Bladder Neoplasm14.2%
94Kidney Neoplasm14.2%
95Ureteral Neoplasms14.2%
96Urethral Neoplasms14.2%
97Urinary tract infection13.9%
98Urologic Neoplasms13.7%
99Horseshoe Kidney13.7%
100Lymphogranuloma Venereum13.6%
101Kidney Calculi13.6%
102Ureteral Calculi13.6%
103Syphilis13.3%
104Pyelocystitis12.9%
105ovarian neoplasm12.7%
106Cystitis12.6%
107Hydronephrosis12.6%
108Hyperoxaluria12.6%
109Kidney Cortex Necrosis12.6%
110Kidney Papillary Necrosis12.6%
111Nephritis12.6%
112Nephrosclerosis12.6%
113Nephrosis12.6%
114Perinephritis12.6%
115Kidney Failure12.6%
116Uremia12.6%
117Ureteral obstruction12.6%
118Ureterocele12.6%
119Urethral Obstruction12.6%
120Urethritis12.6%
121Vesico-Ureteral Reflux12.6%
122Urinary Retention12.6%
123Oxalosis12.6%
124Renal Insufficiency12.6%
125Pregnancy Complications12.2%
126Pyelonephritis12.2%
127Carcinoma, Endometrioid12.1%
128Corpus Luteum Cyst11.9%
129Ovarian Cysts11.9%
130Anovulation11.6%
131Menorrhagia11.6%
132Endometrial Stromal Sarcoma11.6%
133Premature Menopause11.5%
134Hermaphroditism11.5%
135Disorders of Sex Development11.5%
136Polycystic Ovary Syndrome10.4%
137Glomerulonephritis10.4%
138Nephritis, Interstitial10.4%
139Lipoid nephrosis10.4%
140Nephrotic Syndrome10.4%
141Pyelitis10.4%
142Pyonephrosis10.4%
143Urethral Stenosis10.4%
144Nephrogenic Diabetes Insipidus10.4%
145Congenital Nephrogenic Diabetes Insipidus10.4%
146Acute kidney injury10.4%
147Urethral stricture10.4%
148Mesoblastic Nephroma10.2%
149Diabetes Insipidus10.2%
150Hepatorenal Syndrome10.2%
151Genital Neoplasms, Female10.2%
152Renal Cell Carcinoma10.2%
153Papillary Renal Cell Carcinoma10.2%
154Testicular Neoplasms10.1%
155Bacteriuria10.1%
156Diabetic Nephropathy10.1%
157Glycosuria10.1%
158Hematuria10.1%
159Renal hypertension10.1%
160Oliguria10.1%
161Polyuria10.1%
162Proteinuria10.1%
163Pyuria10.1%
164Renal Artery Obstruction10.1%
165Renal Artery Stenosis10.1%
166Urinary Calculi10.1%
167Cystocele10%
168Nephrocalcinosis10%
169Urinary Incontinence10%
170granulosa cell tumor9.5%
171Carcinoma, Ovarian Epithelial9.5%
172Balkan Nephropathy9.3%
173Focal glomerulosclerosis9.3%
174Kidney Failure, Chronic9.3%
175Glycosuria, Renal9.1%
176Enuresis8.5%
177Azotemia8.4%
178Gonadal Dysgenesis8.3%
179Adrenogenital Syndrome8.3%
180Ovotesticular Disorders of Sex Development8.3%
181Nephroblastoma8.3%
182Albuminuria8.3%
183Hemoglobinuria8.3%
184Hypertension, Renovascular8.3%
185Urge Incontinence8.2%
186Hyperandrogenism8.1%
187Denys-Drash Syndrome8.1%
188Glomerulonephritis, Membranoproliferative7.7%
189AIDS-Associated Nephropathy7.1%
190Polyhydramnios7%
191Obstetric Labor Complications7%
192Ectopic Pregnancy7%
193Pregnancy, Prolonged7%
194Puerperal Disorders7%
195Oligohydramnios7%
196Prenatal Injuries7%
197Polycystic Kidney Diseases6.9%
198Diurnal Enuresis6.9%
199Renal Aminoacidurias6.8%
200Fanconi Syndrome6.8%
201Pseudohypoaldosteronism6.8%
202Liddle Syndrome6.8%
203Hemolytic-Uremic Syndrome6.8%
204Abruptio Placentae6.8%
205Placenta Accreta6.8%
206Leydig Cell Tumor6.5%
207Anti-Glomerular Basement Membrane Disease6.3%
208Chorioamnionitis6.2%
209Lupus Nephritis6.2%
210Polycystic Kidney, Autosomal Dominant6.1%
211Cystinuria6.1%
212Atypical Hemolytic Uremic Syndrome6.1%
213Renal tubular acidosis5.9%
214Renal Osteodystrophy5.5%
215Renal rickets5.5%
216Fetal Diseases5.5%
217Pregnancy Complications, Cardiovascular5.5%
218Pregnancy Complications, Neoplastic5.5%
219Turner Syndrome5.4%
220Puerperal Infection5.4%
221Postpartum Hemorrhage5.4%
222Pregnancy Complications, Hematologic5.3%
223Pregnancy Complications, Infectious5.3%
224Kallmann Syndrome5.2%
225Fetal Death5.2%
226Perinatal death5.2%
227Morning Sickness5.1%
228Abortion, Habitual4.5%
229Dystocia4.5%
230Eclampsia4.5%
231Fetal Membranes, Premature Rupture4.5%
232Placental Insufficiency4.5%
233Pre-Eclampsia4.5%
234Prenatal Exposure Delayed Effects4.5%
235HELLP Syndrome4.5%
236Placenta, Retained4.5%
237Hyperphosphaturia4.5%
238Klinefelter Syndrome4.5%
239Gestational Diabetes4.1%
240Zellweger Syndrome4.1%
241Abortion, Veterinary3.6%
242Pregnancy Complications, Parasitic3.6%
243Lactation Disorder3.4%
244Mastitis3.4%
245Depression, Postpartum3.4%
246Embryo Loss3.4%
247Premature Birth3.4%
248Fetal Resorption3.4%
249Hyperemesis Gravidarum3.3%
250Fetal Growth Retardation2.7%
251Trophoblastic Neoplasms2.7%
252Embolism, Amniotic Fluid2.7%
253Fetal Hypoxia2.7%
254Fetal Alcohol Spectrum Disorders2.7%
255Breech Presentation2.7%
256Stillbirth2.7%
257Familial Hypophosphatemic Rickets2.6%
258Galactorrhea2.5%
259Meconium Aspiration Syndrome2%
260Choriocarcinoma1.7%
261Hydatidiform Mole1.6%
262Hydrops Fetalis1.1%
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