MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Balkan Nephropathy

(UMLS:C0004698)

Definition:: A form of chronic interstitial nephritis that is endemic to limited areas of BULGARIA, the former YUGOSLAVIA, and ROMANIA. It is characterized by a progressive shrinking of the KIDNEYS that is often associated with uroepithelial tumors.
UMLS ID:: C0004698
MeSH ID:: D001449

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.419.570.643.150

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.419.570.643.150

Synonym(s)

Balkan Nephropathy

Balkan nephritis syndrome

Balkan nephropathy

Balkan; nephritis

Balkan; nephropathy

DANUBIAN ENDEMIC FAMILIAL NEPHROPATHY

nephritis; Balkan

nephropathy; Balkan

Associated Drug(s)

	Name	Reference(s)	Data Source
1	7-(deoxyadenosin-N(6)-yl)aristolactam I	26845733	CTD
2	Aristolochic Acids	21362632	CTD
3	aristolochic acid I	View details 21613233 21932800 22071594 25209566 26204831 26845733	CTD
4	auranthine	2089255	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Pyelonephritis	49%
2	Glomerulonephritis	36.4%
3	Pyelitis	36.4%
4	Hydronephrosis	29.2%
5	Hyperoxaluria	29.2%
6	Kidney Cortex Necrosis	29.2%
7	Kidney Papillary Necrosis	29.2%
8	Nephrosclerosis	29.2%
9	Nephrosis	29.2%
10	Perinephritis	29.2%
11	Kidney Failure	29.2%
12	Uremia	29.2%
13	Oxalosis	29.2%
14	Renal Insufficiency	29.2%
15	Anuria	28.3%
16	Nephrolithiasis	28.3%
17	Urinary Bladder Diseases	24.1%
18	Ureteral Diseases	24.1%
19	Urethral Diseases	24.1%
20	Urination Disorders	24.1%
21	Urolithiasis	24.1%
22	Focal glomerulosclerosis	24.1%
23	Diabetes Insipidus	23.8%
24	Hepatorenal Syndrome	23.8%
25	Diabetic Nephropathy	23.5%
26	Renal hypertension	23.5%
27	Renal Artery Obstruction	23.5%
28	Renal Artery Stenosis	23.5%
29	Nephrocalcinosis	23.3%
30	Tuberculosis, Renal	22.2%
31	Pyelocystitis	21.3%
32	Glomerulonephritis, Membranoproliferative	20.3%
33	Kidney Neoplasm	19.7%
34	Urinary tract infection	19.6%
35	Ureterolithiasis	17.5%
36	Lipoid nephrosis	17.3%
37	Nephrotic Syndrome	17.3%
38	Pyonephrosis	17.3%
39	Nephrogenic Diabetes Insipidus	17.3%
40	Congenital Nephrogenic Diabetes Insipidus	17.3%
41	Acute kidney injury	17.3%
42	AIDS-Associated Nephropathy	16.7%
43	Anti-Glomerular Basement Membrane Disease	16.5%
44	Lupus Nephritis	16.4%
45	Multicystic Dysplastic Kidney	15.4%
46	Urogenital Abnormalities	14.8%
47	Kidney Calculi	14.6%
48	Azotemia	14.1%
49	Bladder neck obstruction	13.9%
50	Hypertension, Renovascular	13.9%
51	Cystitis	13.1%
52	Ureteral obstruction	13.1%
53	Ureterocele	13.1%
54	Urethral Obstruction	13.1%
55	Urethritis	13.1%
56	Vesico-Ureteral Reflux	13.1%
57	Urinary Retention	13.1%
58	Bladder Exstrophy	13%
59	Epispadias	13%
60	Renal Osteodystrophy	12.9%
61	Renal rickets	12.9%
62	Polycystic Kidney Diseases	11.7%
63	Renal Aminoacidurias	11.6%
64	Fanconi Syndrome	11.6%
65	Pseudohypoaldosteronism	11.6%
66	Liddle Syndrome	11.6%
67	Hemolytic-Uremic Syndrome	11.6%
68	Kidney Failure, Chronic	11.5%
69	Glycosuria, Renal	11.2%
70	Bacteriuria	10.5%
71	Glycosuria	10.5%
72	Hematuria	10.5%
73	Oliguria	10.5%
74	Polyuria	10.5%
75	Proteinuria	10.5%
76	Pyuria	10.5%
77	Urinary Calculi	10.5%
78	Cystocele	10.5%
79	Urinary Incontinence	10.5%
80	Urinary Bladder Fistula	10.4%
81	Bladder Neoplasm	10.4%
82	Ureteral Neoplasms	10.4%
83	Urethral Neoplasms	10.4%
84	Ureteral Calculi	10.4%
85	Mesoblastic Nephroma	10.2%
86	Renal Cell Carcinoma	10.1%
87	Papillary Renal Cell Carcinoma	10.1%
88	Renal tubular acidosis	9.9%
89	Zellweger Syndrome	9.8%
90	Genital Diseases, Male	9.7%
91	Pregnancy Complications	9.5%
92	Infertility	9.3%
93	Enuresis	8.9%
94	Nephroblastoma	8.3%
95	Urethral Stenosis	7.8%
96	Urethral stricture	7.8%
97	Hyperphosphaturia	7.7%
98	Polycystic Kidney, Autosomal Dominant	7.7%
99	Cystinuria	7.7%
100	Atypical Hemolytic Uremic Syndrome	7.6%
101	Hypospadias	7.6%
102	Urologic Neoplasms	7.4%
103	Horseshoe Kidney	7.4%
104	Endometriosis	7.2%
105	Uterine Diseases	7.2%
106	Vaginal Diseases	7.2%
107	Vulvar Diseases	7.2%
108	Endometrioma	7.2%
109	Sexually Transmitted Diseases	6.5%
110	Hermaphroditism	6.3%
111	Disorders of Sex Development	6.3%
112	Albuminuria	6.2%
113	Hemoglobinuria	6.2%
114	Urge Incontinence	6.2%
115	Genital Herpes	6.2%
116	Genital Neoplasms, Male	6%
117	Genital Neoplasms, Female	5.5%
118	Diurnal Enuresis	5.2%
119	Epididymitis	4.9%
120	Penile Diseases	4.9%
121	Prostatic Diseases	4.9%
122	Spermatic Cord Torsion	4.9%
123	Hemospermia	4.9%
124	Testicular Hydrocele	4.9%
125	Uterine Inversion	4.8%
126	Uterine Neoplasms	4.8%
127	Vaginal Neoplasms	4.8%
128	Vulvar Neoplasms	4.8%
129	Uterine Cancer	4.8%
130	Endometritis	4.8%
131	Denys-Drash Syndrome	4.7%
132	Polyhydramnios	4.7%
133	Obstetric Labor Complications	4.7%
134	Ectopic Pregnancy	4.7%
135	Pregnancy, Prolonged	4.7%
136	Puerperal Disorders	4.7%
137	Oligohydramnios	4.7%
138	Prenatal Injuries	4.7%
139	Vesicovaginal Fistula	4.4%
140	Dyspareunia	4.1%
141	Penile Neoplasms	4.1%
142	Prostatic Neoplasms	4.1%
143	Endometrial Hyperplasia	4%
144	Pyometra	4%
145	Vaginitis	4%
146	Vulvitis	4%
147	Vaginal Discharge	4%
148	Vulvodynia	4%
149	Uterine Rupture	3.9%
150	Cryptorchidism	3.9%
151	Fallopian Tube Neoplasms	3.8%
152	Testicular Diseases	3.8%
153	Varicocele	3.8%
154	Spermatocele	3.7%
155	Fetal Diseases	3.7%
156	Pregnancy Complications, Cardiovascular	3.7%
157	Pregnancy Complications, Neoplastic	3.7%
158	Abruptio Placentae	3.7%
159	Placenta Accreta	3.7%
160	Salpingitis	3.6%
161	Vulvovaginitis	3.6%
162	Pregnancy Complications, Hematologic	3.6%
163	Pregnancy Complications, Infectious	3.6%
164	Fetal Death	3.5%
165	Perinatal death	3.5%
166	Morning Sickness	3.5%
167	Gonadal Dysgenesis	3.4%
168	Adrenogenital Syndrome	3.4%
169	Ovotesticular Disorders of Sex Development	3.4%
170	Familial Hypophosphatemic Rickets	3.3%
171	Chorioamnionitis	3.2%
172	Ovarian Diseases	3.1%
173	Adnexitis	3%
174	Pruritus Vulvae	3%
175	Uterine hemorrhage	3%
176	Vaginal Fistula	3%
177	Pelvic Inflammatory Disease	3%
178	Uterine Prolapse	3%
179	Vaginal Prolapse	3%
180	Puerperal Infection	2.9%
181	Postpartum Hemorrhage	2.9%
182	Oophoritis	2.9%
183	Endometrial Neoplasms	2.9%
184	Gestational Diabetes	2.8%
185	ovarian neoplasm	2.8%
186	Uterine Cervical Incompetence	2.8%
187	Balanitis	2.7%
188	Benign prostatic hypertrophy	2.7%
189	Phimosis	2.7%
190	Priapism	2.7%
191	prostatitis	2.7%
192	Prostatic Adenoma	2.7%
193	Benign Prostatic Hyperplasia	2.7%
194	Prostatic Hypertrophy	2.7%
195	Prostatic Hyperplasia	2.7%
196	Abortion, Habitual	2.4%
197	Dystocia	2.4%
198	Eclampsia	2.4%
199	Fetal Membranes, Premature Rupture	2.4%
200	Placental Insufficiency	2.4%
201	Pre-Eclampsia	2.4%
202	Prenatal Exposure Delayed Effects	2.4%
203	HELLP Syndrome	2.4%
204	Placenta, Retained	2.4%
205	Prostatic Neoplasms, Castration-Resistant	2.4%
206	Hyperandrogenism	2.4%
207	Uterine Cervicitis	2.4%
208	Leukorrhea	2.4%
209	Parametritis	2.4%
210	Carcinoma, Endometrioid	2.1%
211	Testicular Neoplasms	2.1%
212	Premature Ejaculation	2.1%
213	Erectile dysfunction	2.1%
214	Orchitis	2%
215	Abortion, Veterinary	1.9%
216	Pregnancy Complications, Parasitic	1.9%
217	Candidiasis, Vulvovaginal	1.9%
218	Bacterial Vaginosis	1.8%
219	Lactation Disorder	1.8%
220	Mastitis	1.8%
221	Depression, Postpartum	1.8%
222	Embryo Loss	1.8%
223	Fetal Resorption	1.8%
224	Hyperemesis Gravidarum	1.8%
225	Trichomonas Vaginitis	1.8%
226	Uterine Perforation	1.8%
227	Ovarian Hyperstimulation Syndrome	1.8%
228	Metrorrhagia	1.8%
229	Chlamydia Infections	1.7%
230	Gonorrhea	1.7%
231	Turner Syndrome	1.6%
232	Azoospermia	1.6%
233	Oligospermia	1.6%
234	Impotence, Vasculogenic	1.6%
235	Asthenozoospermia	1.6%
236	Teratozoospermia	1.6%
237	Aspermia	1.6%
238	Kallmann Syndrome	1.5%
239	Syphilis	1.5%
240	granulosa cell tumor	1.5%
241	Carcinoma, Ovarian Epithelial	1.5%
242	Fetal Growth Retardation	1.5%
243	Trophoblastic Neoplasms	1.5%
244	Embolism, Amniotic Fluid	1.5%
245	Fetal Hypoxia	1.5%
246	Fetal Alcohol Spectrum Disorders	1.5%
247	Corpus Luteum Cyst	1.5%
248	Ovarian Cysts	1.5%
249	Breech Presentation	1.5%
250	Anovulation	1.4%
251	Menorrhagia	1.4%
252	Stillbirth	1.4%
253	Premature Menopause	1.4%
254	Klinefelter Syndrome	1.3%
255	Premature Birth	1.3%
256	Endometrial Stromal Sarcoma	1.2%
257	Lymphogranuloma Venereum	1.1%
258	Meconium Aspiration Syndrome	1.1%
259	Galactorrhea	1%
260	Polycystic Ovary Syndrome	1%
261	Leydig Cell Tumor	0.7%
262	Choriocarcinoma	0.7%
263	Hydatidiform Mole	0.5%
264	Hydrops Fetalis	0.5%

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