MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Spermatic Cord Torsion

(UMLS:C0037856)

Definition:: The twisting of the SPERMATIC CORD due to an anatomical abnormality that left the TESTIS mobile and dangling in the SCROTUM. The initial effect of testicular torsion is obstruction of venous return. Depending on the duration and degree of cord rotation, testicular symptoms range from EDEMA to interrupted arterial flow and testicular pain. If blood flow to testis is absent for 4 to 6 h, SPERMATOGENESIS may be permanently lost.
UMLS ID:: C0037856
MeSH ID:: D013086

Classification:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.294.693

Synonym(s)

Spermatic Cord Torsion

SPERMATIC CORD TORSION

Spermatic cord torsion

TESTICLE TORSION

TESTICULAR TORSION

Testicular Torsion

Testicular torsion

Torsion of Testis

Torsion of spermatic cord

10.

Torsion of testicle

11.

Torsion of testis

12.

Torsion of testis, unspecified

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Cyclosporine	18766458	CTD
2	Sildenafil Citrate	18265987	CTD
3	Sulfasalazine	16626516	CTD
4	Tacrolimus	18766458	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Epididymitis	42.9%
2	Penile Diseases	42.9%
3	Prostatic Diseases	42.9%
4	Hemospermia	42.9%
5	Testicular Hydrocele	42.9%
6	Balanitis	31%
7	Benign prostatic hypertrophy	31%
8	Phimosis	31%
9	Priapism	31%
10	prostatitis	31%
11	Prostatic Adenoma	31%
12	Benign Prostatic Hyperplasia	31%
13	Prostatic Hypertrophy	31%
14	Prostatic Hyperplasia	31%
15	Testicular Diseases	28.6%
16	Varicocele	28.6%
17	Penile Neoplasms	28.2%
18	Prostatic Neoplasms	28.2%
19	Genital Neoplasms, Male	28.1%
20	Infertility	27.9%
21	Spermatocele	27.9%
22	Azoospermia	25.4%
23	Oligospermia	25.4%
24	Impotence, Vasculogenic	25.4%
25	Asthenozoospermia	25.4%
26	Teratozoospermia	25.4%
27	Aspermia	25.4%
28	Prostatic Neoplasms, Castration-Resistant	23%
29	Premature Ejaculation	20.9%
30	Erectile dysfunction	20.9%
31	Orchitis	20.5%
32	Cryptorchidism	17.8%
33	Hypospadias	17.8%
34	Sexually Transmitted Diseases	17.4%
35	Genital Herpes	16.3%
36	Dyspareunia	15.4%
37	Urologic Diseases	15%
38	Testicular Neoplasms	11.6%
39	Urogenital Abnormalities	11.1%
40	Urinary Bladder Diseases	9.3%
41	Kidney Diseases	9.3%
42	Ureteral Diseases	9.3%
43	Urethral Diseases	9.3%
44	Urination Disorders	9.3%
45	Urolithiasis	9.3%
46	Chlamydia Infections	8.2%
47	Gonorrhea	8.2%
48	Anuria	8%
49	Ureterolithiasis	8%
50	Nephrolithiasis	8%
51	Bladder Exstrophy	7.9%
52	Epispadias	7.9%
53	Tuberculosis, Renal	7.8%
54	Lymphogranuloma Venereum	7.3%
55	Multicystic Dysplastic Kidney	7.3%
56	Bladder neck obstruction	7.3%
57	Leydig Cell Tumor	7.3%
58	Syphilis	7%
59	Urinary tract infection	7%
60	Urologic Neoplasms	6.9%
61	Horseshoe Kidney	6.9%
62	Cystitis	6.7%
63	Hydronephrosis	6.7%
64	Hyperoxaluria	6.7%
65	Kidney Cortex Necrosis	6.7%
66	Kidney Papillary Necrosis	6.7%
67	Nephritis	6.7%
68	Nephrosclerosis	6.7%
69	Nephrosis	6.7%
70	Perinephritis	6.7%
71	Kidney Failure	6.7%
72	Uremia	6.7%
73	Ureteral obstruction	6.7%
74	Ureterocele	6.7%
75	Urethral Obstruction	6.7%
76	Urethritis	6.7%
77	Vesico-Ureteral Reflux	6.7%
78	Urinary Retention	6.7%
79	Oxalosis	6.7%
80	Renal Insufficiency	6.7%
81	Urinary Bladder Fistula	6.6%
82	Bladder Neoplasm	6.6%
83	Kidney Neoplasm	6.6%
84	Ureteral Neoplasms	6.6%
85	Urethral Neoplasms	6.6%
86	Pyelocystitis	6.2%
87	Kidney Calculi	6.1%
88	Ureteral Calculi	6.1%
89	Pyelonephritis	5.8%
90	Hermaphroditism	5.6%
91	Disorders of Sex Development	5.6%
92	Glomerulonephritis	5.5%
93	Nephritis, Interstitial	5.5%
94	Lipoid nephrosis	5.5%
95	Nephrotic Syndrome	5.5%
96	Pyelitis	5.5%
97	Pyonephrosis	5.5%
98	Urethral Stenosis	5.5%
99	Nephrogenic Diabetes Insipidus	5.5%
100	Congenital Nephrogenic Diabetes Insipidus	5.5%
101	Acute kidney injury	5.5%
102	Urethral stricture	5.5%
103	Diabetes Insipidus	5.1%
104	Hepatorenal Syndrome	5.1%
105	Bacteriuria	5%
106	Diabetic Nephropathy	5%
107	Glycosuria	5%
108	Hematuria	5%
109	Renal hypertension	5%
110	Oliguria	5%
111	Polyuria	5%
112	Proteinuria	5%
113	Pyuria	5%
114	Renal Artery Obstruction	5%
115	Renal Artery Stenosis	5%
116	Urinary Calculi	5%
117	Cystocele	5%
118	Nephrocalcinosis	5%
119	Urinary Incontinence	5%
120	Balkan Nephropathy	4.9%
121	Focal glomerulosclerosis	4.9%
122	Kidney Failure, Chronic	4.9%
123	Mesoblastic Nephroma	4.7%
124	Renal Cell Carcinoma	4.6%
125	Papillary Renal Cell Carcinoma	4.6%
126	Azotemia	4.2%
127	Albuminuria	4.1%
128	Hemoglobinuria	4.1%
129	Hypertension, Renovascular	4.1%
130	Urge Incontinence	4.1%
131	Enuresis	4.1%
132	Glycosuria, Renal	4.1%
133	Gonadal Dysgenesis	4%
134	Adrenogenital Syndrome	4%
135	Ovotesticular Disorders of Sex Development	4%
136	Glomerulonephritis, Membranoproliferative	3.9%
137	Nephroblastoma	3.7%
138	Hyperandrogenism	3.6%
139	Denys-Drash Syndrome	3.5%
140	Polycystic Kidney Diseases	3.3%
141	AIDS-Associated Nephropathy	3.3%
142	Diurnal Enuresis	3.3%
143	Renal Aminoacidurias	3.3%
144	Fanconi Syndrome	3.3%
145	Pseudohypoaldosteronism	3.3%
146	Liddle Syndrome	3.3%
147	Hemolytic-Uremic Syndrome	3.3%
148	Anti-Glomerular Basement Membrane Disease	3%
149	Lupus Nephritis	3%
150	Polycystic Kidney, Autosomal Dominant	2.9%
151	Cystinuria	2.9%
152	Atypical Hemolytic Uremic Syndrome	2.9%
153	Renal tubular acidosis	2.7%
154	Renal Osteodystrophy	2.5%
155	Renal rickets	2.5%
156	Kallmann Syndrome	2.4%
157	Turner Syndrome	2.3%
158	Hyperphosphaturia	2%
159	Klinefelter Syndrome	2%
160	Zellweger Syndrome	1.8%
161	Familial Hypophosphatemic Rickets	1.1%

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