MetaADEDB 2.0 @ LMMD
Endometriosis
(UMLS:C0014175)
Definition:
A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.
UMLS ID:
C0014175
MeSH ID:
D004715
Classification:
Name:
Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):
C13.351.500.163
Synonym(s)
1.
Endometriosis
2.
ENDOMETRIOSIS
3.
Endo
4.
Endometriosis (clinical)
5.
Endometriosis, NOS
6.
Endometriosis, site unspecified
7.
Endometriosis, unspecified
8.
displacement of the endometrial tissue
9.
endometrioses
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1NorgestrelFAERS: 160
Canada Vigilance: 7		Canada Vigilance
OFFSIDES
SIDER
US FAERS
2NuvaRingFAERS: 68OFFSIDES
US FAERS
3IsotretinoinFAERS: 55US FAERS
4LeuprolideFAERS: 37OFFSIDES
US FAERS
5Dimethyl FumarateFAERS: 22
Canada Vigilance: 1		Canada Vigilance
US FAERS
6etonogestrelFAERS: 20US FAERS
7elagolixFAERS: 1321657270CTD
US FAERS
8Medroxyprogesterone AcetateFAERS: 1223183084CTD
US FAERS
9Ortho EvraFAERS: 11US FAERS
10GoserelinFAERS: 109230649CTD
OFFSIDES
US FAERS
114-hydroxybutyric acidFAERS: 9US FAERS
12EstradiolFAERS: 9
Canada Vigilance: 4		Canada Vigilance
OFFSIDES
SIDER
US FAERS
13OndansetronFAERS: 9US FAERS
14Estrogens, Conjugated (USP)FAERS: 8US FAERS
15Fingolimod HydrochlorideFAERS: 8
Canada Vigilance: 1		Canada Vigilance
US FAERS
16TamoxifenFAERS: 8US FAERS
17AlendronateFAERS: 7US FAERS
18CopperFAERS: 6US FAERS
19PregabalinFAERS: 6US FAERS
20ambrisentanFAERS: 6US FAERS
21Duloxetine HydrochlorideFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
22Glatiramer AcetateFAERS: 5US FAERS
23ThyroxineFAERS: 5US FAERS
24rofecoxibFAERS: 515652904CTD
OFFSIDES
US FAERS
25AripiprazoleFAERS: 4US FAERS
26CitalopramFAERS: 4US FAERS
27DesogestrelFAERS: 4US FAERS
28Lupaneta PackFAERS: 4US FAERS
29MifepristoneFAERS: 416134523CTD
US FAERS
30QlairaFAERS: 4US FAERS
31Quetiapine FumarateFAERS: 4US FAERS
32Raloxifene HydrochlorideFAERS: 4US FAERS
33ThyroxineFAERS: 4US FAERS
34apixabanFAERS: 4US FAERS
35norgestimate, ethinyl estradiol drug combinationFAERS: 4OFFSIDES
US FAERS
36AnastrozoleFAERS: 3OFFSIDES
US FAERS
37Ethinyl Estradiol-Norgestrel CombinationFAERS: 3US FAERS
38FentanylFAERS: 3US FAERS
39Imatinib MesylateFAERS: 3US FAERS
40Norethindrone acetate and ethinyl estradiolFAERS: 3US FAERS
41OmeprazoleFAERS: 3US FAERS
42Rosuvastatin CalciumFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
43TamoxifenFAERS: 3OFFSIDES
SIDER
US FAERS
44TopiramateFAERS: 3US FAERS
45exemestaneFAERS: 3OFFSIDES
US FAERS
46teriflunomideFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
47AlbuterolFAERS: 2US FAERS
48ClomipheneFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
49CyclosporineFAERS: 2US FAERS
50DeferasiroxFAERS: 2US FAERS
51DiclofenacFAERS: 2OFFSIDES
US FAERS
52EsomeprazoleFAERS: 2US FAERS
53HydrocortisoneFAERS: 2US FAERS
54LamotrigineFAERS: 2US FAERS
55LetrozoleFAERS: 2US FAERS
56SertralineFAERS: 2US FAERS
57TeriparatideFAERS: 2US FAERS
58VareniclineFAERS: 2US FAERS
59tegaserodFAERS: 2US FAERS
60tofacitinibFAERS: 2US FAERS
61(3S,4R)-3-(1,3-Benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium;methanesulfonateFAERS: 1US FAERS
624-AminopyridineFAERS: 1US FAERS
634-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideFAERS: 1US FAERS
64Atacand hctFAERS: 1US FAERS
65Atomoxetine HydrochlorideFAERS: 1US FAERS
66CabergolineFAERS: 1OFFSIDES
US FAERS
67CarbamazepineFAERS: 1US FAERS
68CelecoxibFAERS: 115652904CTD
US FAERS
69CitalopramFAERS: 1US FAERS
70CitalopramFAERS: 1US FAERS
71DesogestrelFAERS: 1US FAERS
72Erlotinib HydrochlorideFAERS: 1US FAERS
73ExenatideFAERS: 1US FAERS
74Ezetimibe, Simvastatin Drug CombinationFAERS: 1US FAERS
75FluoxetineFAERS: 1US FAERS
76Insulin GlargineFAERS: 1US FAERS
77LubiprostoneFAERS: 1US FAERS
78Lurasidone HydrochlorideFAERS: 1US FAERS
79MethylergonovineFAERS: 1US FAERS
80MethylprednisoloneFAERS: 1US FAERS
81MetoclopramideFAERS: 1US FAERS
82MetoprololFAERS: 1US FAERS
83MinocyclineFAERS: 1US FAERS
84MitoxantroneFAERS: 1US FAERS
85NicotineFAERS: 1US FAERS
86NorinylFAERS: 1US FAERS
87OrlistatFAERS: 1OFFSIDES
US FAERS
88OspemifeneFAERS: 1US FAERS
89OxaprozinFAERS: 1US FAERS
90PantoprazoleFAERS: 1US FAERS
91ParoxetineFAERS: 1US FAERS
92PhentermineFAERS: 1US FAERS
93PrednisoneFAERS: 1US FAERS
94RivaroxabanFAERS: 1US FAERS
95SofosbuvirFAERS: 1US FAERS
96TenofovirFAERS: 1US FAERS
97Tranexamic AcidFAERS: 1US FAERS
98Valproic AcidFAERS: 1US FAERS
99Venlafaxine HydrochlorideFAERS: 1US FAERS
100Zoledronic AcidFAERS: 1US FAERS
101aliskirenFAERS: 1US FAERS
102beyazFAERS: 1US FAERS
103dienogestFAERS: 1US FAERS
104linaclotideFAERS: 1US FAERS
105mirabegronFAERS: 1US FAERS
106osimertinibFAERS: 1US FAERS
107palbociclibFAERS: 1US FAERS
108tegaserodFAERS: 1US FAERS
109ulipristal acetateFAERS: 1US FAERS
1102,2',4,6,6'-pentachlorobiphenyl29535049CTD
1112,3,4,7,8-pentachlorodibenzofuran9294722CTD
1123,4,3',4'-tetrachlorobiphenyl11134554CTD
113AlbuterolCanada Vigilance: 1Canada Vigilance
114AlprazolamOFFSIDES
115AmoxicillinOFFSIDES
116Atomoxetine HydrochlorideOFFSIDES
117BupropionOFFSIDES
118BuspironeOFFSIDES
119Caffeine8823059CTD
120Calcium CitrateOFFSIDES
121CapecitabineOFFSIDES
122CarisoprodolOFFSIDES
123CaspofunginOFFSIDES
124CefdinirOFFSIDES
125CetirizineOFFSIDES
126ClindamycinSIDER
127ClomipheneSIDER
128ClomipramineSIDER
129D-GalactosamineOFFSIDES
130Danazol

View details

2616424
2741896
3750010
6102641
6453026
6453071
6562983
9248340
9696224
9764869
11757752
15221322
19148548
21261738
 		CTD
131Dichlorodiphenyl Dichloroethylene19654915CTD
132Dinoprost25446850CTD
133EphedrineOFFSIDES
134EtodolacOFFSIDES
135EtoricoxibOFFSIDES
136Fluocinolone AcetonideOFFSIDES
137Fluoxetine9098464CTD
OFFSIDES
138FulvestrantOFFSIDES
139Ibuprofen3750010
15652904		CTD
OFFSIDES
140Indomethacin15652904CTD
141Leuprolide

View details

9230649
9532352
9628521
9951575
11346231
17611838
18464947
25462211
 		CTD
142Lynestrenol6562983CTD
143Mefenamic AcidOFFSIDES
144MelatoninOFFSIDES
145MeperidineOFFSIDES
146MethotrexateOFFSIDES
147MinocyclineOFFSIDES
148Mometasone FuroateSIDER
149Naproxen15652904CTD
150Norinyl30675821CTD
151NortriptylineOFFSIDES
152PhenolphthaleinOFFSIDES
153Piperacillin, Tazobactam Drug CombinationOFFSIDES
154Polychlorinated Biphenyls19654915CTD
155Polychlorinated Dibenzodioxins

View details

9294722
10568697
11134554
11248145
 		CTD
156Progesterone

View details

8529825
16134523
20864642
23284138
 		CTD
SIDER
157Raloxifene HydrochlorideOFFSIDES
158Resveratrol23386644
25462211		CTD
159RibavirinOFFSIDES
160SaquinavirOFFSIDES
161ScopolamineOFFSIDES
162Simvastatin23386644CTD
163Sulindac15652904CTD
164SumatriptanSIDER
165ThiothixeneOFFSIDES
166TretinoinOFFSIDES
167Venlafaxine HydrochlorideSIDER
168VerapamilOFFSIDES
169alosetronOFFSIDES
170bisphenol A25205760
28400829		CTD
171eletriptanOFFSIDES
172estradiol 17 beta-cypionateOFFSIDES
173etizolamOFFSIDES
174ferrous fumarateOFFSIDES
175mono-(2-ethylhexyl)phthalate20185384CTD
176monobutyl phthalate20185384CTD
177naratriptanOFFSIDES
178oxybutyninOFFSIDES
179posaconazoleOFFSIDES
180tandospironeOFFSIDES
181tegaserodOFFSIDES
182tibolone25673440CTD
OFFSIDES
183tizanidineOFFSIDES
184trospium chlorideOFFSIDES
185zafirlukast15019815CTD
Similar ADE(s)
NameSemantic Similarity
1Uterine Diseases46.7%
2Vaginal Diseases46.7%
3Vulvar Diseases46.7%
4Endometritis41.6%
5Salpingitis37.6%
6Vulvovaginitis37.6%
7Endometrial Hyperplasia34.4%
8Pyometra34.4%
9Vaginitis34.4%
10Vulvitis34.4%
11Vaginal Discharge34.4%
12Vulvodynia34.4%
13Infertility31.8%
14Uterine Cervicitis28.5%
15Leukorrhea28.5%
16Oophoritis28.5%
17Parametritis28.5%
18Uterine Inversion27.5%
19Candidiasis, Vulvovaginal25.5%
20Uterine Neoplasms24.4%
21Vaginal Neoplasms24.4%
22Vulvar Neoplasms24.4%
23Uterine Cancer24.4%
24Ovarian Diseases23.6%
25Adnexitis23.1%
26Pruritus Vulvae23.1%
27Uterine hemorrhage23.1%
28Vaginal Fistula23.1%
29Pelvic Inflammatory Disease23.1%
30Uterine Prolapse22.8%
31Vaginal Prolapse22.8%
32Uterine Cervical Incompetence22.2%
33Urologic Diseases22%
34Fallopian Tube Neoplasms21.5%
35Uterine Rupture21%
36Endometrial Neoplasms20.1%
37Sexually Transmitted Diseases20%
38Bacterial Vaginosis19.6%
39Trichomonas Vaginitis19.1%
40Uterine Perforation19.1%
41Ovarian Hyperstimulation Syndrome19.1%
42Metrorrhagia18.9%
43Genital Herpes18.8%
44Pregnancy Complications18.5%
45Dyspareunia17.6%
46Vesicovaginal Fistula17.4%
47Urogenital Abnormalities16.4%
48ovarian neoplasm14.7%
49Corpus Luteum Cyst14.6%
50Ovarian Cysts14.6%
51Anovulation14.3%
52Menorrhagia14.3%
53Premature Menopause14.1%
54Endometrial Stromal Sarcoma13.7%
55Carcinoma, Endometrioid13.7%
56Urinary Bladder Diseases13.6%
57Kidney Diseases13.6%
58Ureteral Diseases13.6%
59Urethral Diseases13.6%
60Urination Disorders13.6%
61Urolithiasis13.6%
62Genital Neoplasms, Female13.3%
63Polycystic Ovary Syndrome12.8%
64Anuria11.8%
65Ureterolithiasis11.8%
66Nephrolithiasis11.8%
67Bladder Exstrophy11.7%
68Epispadias11.7%
69Tuberculosis, Renal11.6%
70Multicystic Dysplastic Kidney10.8%
71granulosa cell tumor10.8%
72Carcinoma, Ovarian Epithelial10.8%
73Bladder neck obstruction10.7%
74Polyhydramnios10.3%
75Obstetric Labor Complications10.3%
76Ectopic Pregnancy10.3%
77Pregnancy, Prolonged10.3%
78Puerperal Disorders10.3%
79Urinary tract infection10.3%
80Oligohydramnios10.3%
81Prenatal Injuries10.3%
82Urologic Neoplasms10.2%
83Horseshoe Kidney10.2%
84Cystitis9.9%
85Hydronephrosis9.9%
86Hyperoxaluria9.9%
87Kidney Cortex Necrosis9.9%
88Kidney Papillary Necrosis9.9%
89Nephritis9.9%
90Nephrosclerosis9.9%
91Nephrosis9.9%
92Perinephritis9.9%
93Kidney Failure9.9%
94Uremia9.9%
95Ureteral obstruction9.9%
96Ureterocele9.9%
97Urethral Obstruction9.9%
98Urethritis9.9%
99Vesico-Ureteral Reflux9.9%
100Urinary Retention9.9%
101Oxalosis9.9%
102Renal Insufficiency9.9%
103Urinary Bladder Fistula9.8%
104Bladder Neoplasm9.8%
105Kidney Neoplasm9.8%
106Ureteral Neoplasms9.8%
107Urethral Neoplasms9.8%
108Chlamydia Infections9.5%
109Gonorrhea9.5%
110Pyelocystitis9.1%
111Kidney Calculi9.1%
112Ureteral Calculi9.1%
113Abruptio Placentae8.9%
114Placenta Accreta8.9%
115Pyelonephritis8.6%
116Lymphogranuloma Venereum8.4%
117Hermaphroditism8.2%
118Disorders of Sex Development8.2%
119Syphilis8.1%
120Glomerulonephritis8.1%
121Nephritis, Interstitial8.1%
122Lipoid nephrosis8.1%
123Nephrotic Syndrome8.1%
124Pyelitis8.1%
125Pyonephrosis8.1%
126Urethral Stenosis8.1%
127Nephrogenic Diabetes Insipidus8.1%
128Congenital Nephrogenic Diabetes Insipidus8.1%
129Hypospadias8.1%
130Acute kidney injury8.1%
131Urethral stricture8.1%
132Diabetes Insipidus7.6%
133Hepatorenal Syndrome7.6%
134Bacteriuria7.4%
135Diabetic Nephropathy7.4%
136Glycosuria7.4%
137Hematuria7.4%
138Renal hypertension7.4%
139Oliguria7.4%
140Polyuria7.4%
141Proteinuria7.4%
142Pyuria7.4%
143Renal Artery Obstruction7.4%
144Renal Artery Stenosis7.4%
145Urinary Calculi7.4%
146Chorioamnionitis7.4%
147Cystocele7.4%
148Nephrocalcinosis7.4%
149Urinary Incontinence7.4%
150Fetal Diseases7.3%
151Pregnancy Complications, Cardiovascular7.3%
152Pregnancy Complications, Neoplastic7.3%
153Balkan Nephropathy7.2%
154Focal glomerulosclerosis7.2%
155Kidney Failure, Chronic7.2%
156Pregnancy Complications, Hematologic7%
157Pregnancy Complications, Infectious7%
158Mesoblastic Nephroma6.9%
159Renal Cell Carcinoma6.9%
160Papillary Renal Cell Carcinoma6.9%
161Fetal Death6.8%
162Perinatal death6.8%
163Morning Sickness6.7%
164Abortion, Habitual6.7%
165Dystocia6.7%
166Eclampsia6.7%
167Fetal Membranes, Premature Rupture6.7%
168Placental Insufficiency6.7%
169Pre-Eclampsia6.7%
170Prenatal Exposure Delayed Effects6.7%
171Puerperal Infection6.7%
172HELLP Syndrome6.7%
173Placenta, Retained6.7%
174Postpartum Hemorrhage6.6%
175Azotemia6.2%
176Albuminuria6.1%
177Hemoglobinuria6.1%
178Hypertension, Renovascular6.1%
179Glycosuria, Renal6%
180Urge Incontinence6%
181Enuresis6%
182Gonadal Dysgenesis5.9%
183Adrenogenital Syndrome5.9%
184Ovotesticular Disorders of Sex Development5.9%
185Glomerulonephritis, Membranoproliferative5.8%
186Nephroblastoma5.5%
187Hyperandrogenism5.4%
188Denys-Drash Syndrome5.2%
189Gestational Diabetes5.1%
190Polycystic Kidney Diseases4.9%
191Premature Birth4.9%
192AIDS-Associated Nephropathy4.9%
193Diurnal Enuresis4.9%
194Renal Aminoacidurias4.9%
195Fanconi Syndrome4.9%
196Pseudohypoaldosteronism4.9%
197Liddle Syndrome4.9%
198Hemolytic-Uremic Syndrome4.8%
199Abortion, Veterinary4.8%
200Pregnancy Complications, Parasitic4.8%
201Anti-Glomerular Basement Membrane Disease4.5%
202Lactation Disorder4.4%
203Mastitis4.4%
204Depression, Postpartum4.4%
205Embryo Loss4.4%
206Lupus Nephritis4.4%
207Fetal Resorption4.4%
208Hyperemesis Gravidarum4.4%
209Polycystic Kidney, Autosomal Dominant4.3%
210Cystinuria4.3%
211Atypical Hemolytic Uremic Syndrome4.3%
212Renal tubular acidosis4%
213Renal Osteodystrophy3.6%
214Renal rickets3.6%
215Kallmann Syndrome3.5%
216Turner Syndrome3.5%
217Fetal Growth Retardation3.4%
218Trophoblastic Neoplasms3.4%
219Embolism, Amniotic Fluid3.4%
220Fetal Hypoxia3.4%
221Fetal Alcohol Spectrum Disorders3.4%
222Breech Presentation3.3%
223Stillbirth3.3%
224Galactorrhea3.3%
225Hyperphosphaturia3%
226Klinefelter Syndrome3%
227Zellweger Syndrome2.7%
228Meconium Aspiration Syndrome2.3%
229Hydatidiform Mole2%
230Choriocarcinoma2%
231Familial Hypophosphatemic Rickets1.7%
232Hydrops Fetalis1.2%
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