MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Oligohydramnios

(UMLS:C0079924)

Definition:: A condition of abnormally low AMNIOTIC FLUID volume. Principal causes include malformations of fetal URINARY TRACT; FETAL GROWTH RETARDATION; GESTATIONAL HYPERTENSION; nicotine poisoning; and PROLONGED PREGNANCY.
UMLS ID:: C0079924
MeSH ID:: D016104

Classification:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.703.560

Synonym(s)

Oligohydramnios

Deficient liquor

Low levels of amniotic fluid

OLIGOHYDRAMNIOS

Oligohydramnios, NOS

Reduced Amniotic Fluid

Reduced liquor volume

Scanty liquor

oligohydramnios

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Valsartan	FAERS: 54 Canada Vigilance: 1		Canada Vigilance US FAERS
2	Olmesartan Medoxomil	FAERS: 32		US FAERS
3	Arthrotec	FAERS: 25		US FAERS
4	Lisinopril	FAERS: 21 Canada Vigilance: 1		Canada Vigilance US FAERS
5	Losartan	FAERS: 20		US FAERS
6	candesartan	FAERS: 20	20132879	CTD OFFSIDES US FAERS
7	17 alpha-Hydroxyprogesterone Caproate	FAERS: 17		US FAERS
8	candesartan cilexetil	FAERS: 17		OFFSIDES US FAERS
9	Fluoxetine	FAERS: 16		US FAERS
10	Ondansetron	FAERS: 12		US FAERS
11	Norgestrel	FAERS: 11		US FAERS
12	Losartan	FAERS: 10		OFFSIDES US FAERS
13	Diclofenac	FAERS: 9		US FAERS
14	Ibuprofen	FAERS: 8		US FAERS
15	Dexamethasone	FAERS: 7		US FAERS
16	Indomethacin	FAERS: 7	View details 1923225 2006947 3050004 3191072 6772782 8163032 8308583	CTD US FAERS
17	Venlafaxine Hydrochloride	FAERS: 7		US FAERS
18	Aripiprazole	FAERS: 6		US FAERS
19	Naproxen	FAERS: 6		US FAERS
20	Metformin	FAERS: 5		US FAERS
21	Methotrexate	FAERS: 5		US FAERS
22	Nadolol	FAERS: 5		US FAERS
23	benazepril	FAERS: 5		US FAERS
24	Diclofenac	FAERS: 4		US FAERS
25	Lamotrigine	FAERS: 4		OFFSIDES US FAERS
26	Levetiracetam	FAERS: 4		US FAERS
27	NuvaRing	FAERS: 4		US FAERS
28	Thyroxine	FAERS: 4		US FAERS
29	Diovan Hct	FAERS: 3		US FAERS
30	Duloxetine Hydrochloride	FAERS: 3		US FAERS
31	Enalapril	FAERS: 3		US FAERS
32	Leflunomide	FAERS: 3		US FAERS
33	Medroxyprogesterone Acetate	FAERS: 3		US FAERS
34	Paclitaxel	FAERS: 3		US FAERS
35	Paroxetine	FAERS: 3		US FAERS
36	olmesartan	FAERS: 3		US FAERS
37	Acetaminophen	FAERS: 2		US FAERS
38	Carbamazepine	FAERS: 2		US FAERS
39	Citalopram	FAERS: 2		US FAERS
40	Clozapine	FAERS: 2		US FAERS
41	Digoxin	FAERS: 2		US FAERS
42	Furosemide	FAERS: 2		US FAERS
43	Hydroxyurea	FAERS: 2		US FAERS
44	Imatinib Mesylate	FAERS: 2		US FAERS
45	Mesalamine	FAERS: 2		US FAERS
46	Metronidazole	FAERS: 2		US FAERS
47	Naproxen	FAERS: 2		US FAERS
48	Nicotine	FAERS: 2		US FAERS
49	Ortho Evra	FAERS: 2		US FAERS
50	Penicillamine	FAERS: 2		US FAERS
51	Sulfasalazine	FAERS: 2		US FAERS
52	Sumatriptan	FAERS: 2		US FAERS
53	Telmisartan	FAERS: 2		US FAERS
54	Thyroxine	FAERS: 2		US FAERS
55	Topiramate	FAERS: 2		US FAERS
56	Warfarin	FAERS: 2		US FAERS
57	sapropterin	FAERS: 2		US FAERS
58	tofacitinib	FAERS: 2		US FAERS
59	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
60	Albuterol	FAERS: 1		US FAERS
61	Betamethasone	FAERS: 1		US FAERS
62	Buprenorphine	FAERS: 1		OFFSIDES US FAERS
63	Cabergoline	FAERS: 1		OFFSIDES US FAERS
64	Ceftriaxone	FAERS: 1		US FAERS
65	Clarithromycin	FAERS: 1		US FAERS
66	Clomiphene	FAERS: 1		US FAERS
67	Deamino Arginine Vasopressin	FAERS: 1		US FAERS
68	Dexlansoprazole	FAERS: 1		US FAERS
69	Dimethyl Fumarate	FAERS: 1		US FAERS
70	Dinoprostone	FAERS: 1		US FAERS
71	Enalapril	FAERS: 1	2301491 7951836 16147831	CTD US FAERS
72	Erlotinib Hydrochloride	FAERS: 1		US FAERS
73	Erlotinib Hydrochloride	FAERS: 1		US FAERS
74	Fingolimod Hydrochloride	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
75	Fluoxetine	FAERS: 1		US FAERS
76	Iloprost	FAERS: 1		OFFSIDES US FAERS
77	Insulin Detemir	FAERS: 1		US FAERS
78	Interleukin 1 Receptor Antagonist Protein	FAERS: 1		US FAERS
79	Mefenamic Acid	FAERS: 1		US FAERS
80	Metformin	FAERS: 1		US FAERS
81	Methylphenidate	FAERS: 1		US FAERS
82	Metoprolol	FAERS: 1		US FAERS
83	Misoprostol	FAERS: 1		OFFSIDES US FAERS
84	Nafarelin	FAERS: 1		US FAERS
85	Nevirapine	FAERS: 1		OFFSIDES US FAERS
86	Omeprazole	FAERS: 1		US FAERS
87	Orlistat	FAERS: 1		US FAERS
88	Oseltamivir	FAERS: 1		US FAERS
89	Oxcarbazepine	FAERS: 1		US FAERS
90	Pantoprazole	FAERS: 1		US FAERS
91	Piroxicam	FAERS: 1	7819009	CTD US FAERS
92	Progesterone	FAERS: 1		US FAERS
93	Risperidone	FAERS: 1		US FAERS
94	Rivaroxaban	FAERS: 1		US FAERS
95	Simvastatin	FAERS: 1		US FAERS
96	Sotalol	FAERS: 1		US FAERS
97	Tenofovir	FAERS: 1		US FAERS
98	Tolterodine Tartrate	FAERS: 1		US FAERS
99	Valproic Acid	FAERS: 1		US FAERS
100	Valproic Acid	FAERS: 1		US FAERS
101	Zidovudine	FAERS: 1 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
102	almotriptan	FAERS: 1		US FAERS
103	eprosartan	FAERS: 1		US FAERS
104	erythromycin stearate	FAERS: 1		US FAERS
105	prednisolone phosphate	FAERS: 1		US FAERS
106	rofecoxib	FAERS: 1		US FAERS
107	tegaserod	FAERS: 1		US FAERS
108	telmisartan, hydrochlorothiazide drug combination	FAERS: 1		US FAERS
109	17-alpha-Hydroxyprogesterone			SIDER
110	5-O-[1-[3,3-Diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydron;chloride			OFFSIDES
111	5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydron;chloride			OFFSIDES
112	Aspirin	Canada Vigilance: 2	6772782	CTD Canada Vigilance
113	Azathioprine			OFFSIDES
114	Bleomycin			OFFSIDES
115	Caffeine			OFFSIDES
116	Captopril			SIDER
117	Dacarbazine			OFFSIDES
118	Darunavir			OFFSIDES
119	Doxorubicin			OFFSIDES
120	Erythromycin			OFFSIDES
121	Fosinopril			SIDER
122	Goserelin			OFFSIDES
123	Isoflurane			OFFSIDES
124	Ketoprofen		15067231	CTD
125	Labetalol			OFFSIDES
126	Linezolid			OFFSIDES
127	Meropenem			OFFSIDES
128	Methyldopa			OFFSIDES
129	Mifepristone			OFFSIDES
130	Milnacipran			OFFSIDES
131	Nelfinavir			OFFSIDES
132	Nicardipine			OFFSIDES
133	Paroxetine	Canada Vigilance: 1		Canada Vigilance
134	Phentermine			OFFSIDES
135	Potassium			OFFSIDES
136	Pramipexole			OFFSIDES
137	Prazosin			OFFSIDES
138	Prednisone			OFFSIDES
139	Pyridostigmine Bromide			OFFSIDES
140	Ribavirin			OFFSIDES
141	Sevelamer			OFFSIDES
142	Stavudine			OFFSIDES
143	Tamoxifen			OFFSIDES
144	Tenofovir			OFFSIDES
145	Terbutaline			OFFSIDES
146	Vinblastine			OFFSIDES
147	Vinorelbine			OFFSIDES
148	alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination			OFFSIDES
149	alpha-Tocopherol			OFFSIDES
150	benidipine			OFFSIDES
151	buflomedil			OFFSIDES
152	ethyl loflazepate			OFFSIDES
153	fosamprenavir			OFFSIDES
154	lamivudine, zidovudine drug combination			OFFSIDES
155	mepronizine			OFFSIDES
156	nimesulide			OFFSIDES
157	prednisolone acetate			OFFSIDES
158	prednisolone phosphate			OFFSIDES
159	sapropterin			OFFSIDES
160	sibutramine			OFFSIDES
161	zolmitriptan			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Polyhydramnios	42.9%
2	Obstetric Labor Complications	42.9%
3	Ectopic Pregnancy	42.9%
4	Pregnancy, Prolonged	42.9%
5	Puerperal Disorders	42.9%
6	Prenatal Injuries	42.9%
7	Abruptio Placentae	40.9%
8	Placenta Accreta	40.9%
9	Chorioamnionitis	34.7%
10	Abortion, Habitual	31%
11	Dystocia	31%
12	Eclampsia	31%
13	Fetal Membranes, Premature Rupture	31%
14	Placental Insufficiency	31%
15	Pre-Eclampsia	31%
16	Prenatal Exposure Delayed Effects	31%
17	HELLP Syndrome	31%
18	Placenta, Retained	31%
19	Puerperal Infection	30.5%
20	Postpartum Hemorrhage	30.3%
21	Fetal Diseases	30%
22	Pregnancy Complications, Cardiovascular	30%
23	Pregnancy Complications, Neoplastic	30%
24	Pregnancy Complications, Hematologic	28.6%
25	Pregnancy Complications, Infectious	28.6%
26	Fetal Death	27.9%
27	Perinatal death	27.9%
28	Morning Sickness	27.6%
29	Uterine Inversion	25.8%
30	Premature Birth	25.4%
31	Female Urogenital Diseases	23.1%
32	Abortion, Veterinary	22%
33	Pregnancy Complications, Parasitic	22%
34	Uterine Cervical Incompetence	21.5%
35	Gestational Diabetes	20.9%
36	Lactation Disorder	20.5%
37	Mastitis	20.5%
38	Depression, Postpartum	20.5%
39	Embryo Loss	20.5%
40	Fetal Resorption	20.2%
41	Hyperemesis Gravidarum	20.1%
42	Uterine Rupture	19.7%
43	Galactorrhea	16.7%
44	Fetal Growth Retardation	15.5%
45	Trophoblastic Neoplasms	15.5%
46	Embolism, Amniotic Fluid	15.4%
47	Fetal Hypoxia	15.4%
48	Fetal Alcohol Spectrum Disorders	15.4%
49	Breech Presentation	15%
50	Stillbirth	14.9%
51	Hydatidiform Mole	11.1%
52	Endometritis	10.5%
53	Meconium Aspiration Syndrome	10.5%
54	Endometriosis	10.3%
55	Uterine Diseases	10.3%
56	Vaginal Diseases	10.3%
57	Vulvar Diseases	10.3%
58	Endometrioma	10.3%
59	Urologic Diseases	10%
60	Choriocarcinoma	9.9%
61	Salpingitis	9.9%
62	Vulvovaginitis	9.9%
63	Endometrial Hyperplasia	8.5%
64	Pyometra	8.5%
65	Vaginitis	8.5%
66	Vulvitis	8.5%
67	Vaginal Discharge	8.5%
68	Vulvodynia	8.5%
69	Uterine Neoplasms	8.3%
70	Vaginal Neoplasms	8.3%
71	Vulvar Neoplasms	8.3%
72	Uterine Cancer	8.3%
73	Fallopian Tube Neoplasms	7.8%
74	Uterine Cervicitis	7.6%
75	Leukorrhea	7.6%
76	Parametritis	7.6%
77	Oophoritis	7.4%
78	Urogenital Abnormalities	7.4%
79	Endometrial Neoplasms	7.3%
80	Vesicovaginal Fistula	7.3%
81	Candidiasis, Vulvovaginal	7%
82	Urinary Bladder Diseases	7%
83	Infertility	7%
84	Kidney Diseases	7%
85	Ureteral Diseases	7%
86	Urethral Diseases	7%
87	Urination Disorders	7%
88	Urolithiasis	7%
89	Genital Neoplasms, Female	6.8%
90	Anuria	6.7%
91	Ureterolithiasis	6.7%
92	Nephrolithiasis	6.7%
93	Bladder neck obstruction	6.3%
94	Hydrops Fetalis	6.2%
95	Bladder Exstrophy	6.2%
96	Epispadias	6.2%
97	Tuberculosis, Renal	6.1%
98	Carcinoma, Endometrioid	6%
99	Multicystic Dysplastic Kidney	5.9%
100	Ovarian Diseases	5.7%
101	Pyelocystitis	5.7%
102	Adnexitis	5.6%
103	Cystitis	5.6%
104	Hydronephrosis	5.6%
105	Hyperoxaluria	5.6%
106	Kidney Cortex Necrosis	5.6%
107	Kidney Papillary Necrosis	5.6%
108	Nephritis	5.6%
109	Nephrosclerosis	5.6%
110	Nephrosis	5.6%
111	Perinephritis	5.6%
112	Pruritus Vulvae	5.6%
113	Kidney Failure	5.6%
114	Uremia	5.6%
115	Ureteral obstruction	5.6%
116	Ureterocele	5.6%
117	Urethral Obstruction	5.6%
118	Urethritis	5.6%
119	Uterine hemorrhage	5.6%
120	Vaginal Fistula	5.6%
121	Vesico-Ureteral Reflux	5.6%
122	Urinary Retention	5.6%
123	Pelvic Inflammatory Disease	5.6%
124	Oxalosis	5.6%
125	Renal Insufficiency	5.6%
126	Uterine Prolapse	5.6%
127	Vaginal Prolapse	5.6%
128	Urinary Bladder Fistula	5.5%
129	Bladder Neoplasm	5.5%
130	Kidney Neoplasm	5.5%
131	Ureteral Neoplasms	5.5%
132	Urethral Neoplasms	5.5%
133	Pyelonephritis	5.5%
134	Kidney Calculi	5.5%
135	Ureteral Calculi	5.5%
136	Endometrial Stromal Sarcoma	5.4%
137	ovarian neoplasm	5.3%
138	Urinary tract infection	5.3%
139	Urologic Neoplasms	5.2%
140	Horseshoe Kidney	5.2%
141	Bacterial Vaginosis	5.1%
142	Trichomonas Vaginitis	5%
143	Uterine Perforation	5%
144	Ovarian Hyperstimulation Syndrome	5%
145	Glomerulonephritis	5%
146	Metrorrhagia	5%
147	Nephritis, Interstitial	5%
148	Lipoid nephrosis	5%
149	Nephrotic Syndrome	5%
150	Pyelitis	5%
151	Pyonephrosis	5%
152	Urethral Stenosis	5%
153	Nephrogenic Diabetes Insipidus	5%
154	Congenital Nephrogenic Diabetes Insipidus	5%
155	Acute kidney injury	5%
156	Urethral stricture	5%
157	Balkan Nephropathy	4.7%
158	Focal glomerulosclerosis	4.7%
159	Kidney Failure, Chronic	4.7%
160	Sexually Transmitted Diseases	4.3%
161	Diabetes Insipidus	4.3%
162	Hepatorenal Syndrome	4.3%
163	Dyspareunia	4.3%
164	Bacteriuria	4.2%
165	Diabetic Nephropathy	4.2%
166	Glycosuria	4.2%
167	Hematuria	4.2%
168	Renal hypertension	4.2%
169	Oliguria	4.2%
170	Polyuria	4.2%
171	Proteinuria	4.2%
172	Pyuria	4.2%
173	Renal Artery Obstruction	4.2%
174	Renal Artery Stenosis	4.2%
175	Urinary Calculi	4.2%
176	Mesoblastic Nephroma	4.2%
177	Renal Cell Carcinoma	4.2%
178	Cystocele	4.2%
179	Hermaphroditism	4.2%
180	Nephrocalcinosis	4.2%
181	Disorders of Sex Development	4.2%
182	Urinary Incontinence	4.2%
183	Papillary Renal Cell Carcinoma	4.2%
184	Hypospadias	4.1%
185	granulosa cell tumor	4.1%
186	Carcinoma, Ovarian Epithelial	4.1%
187	Genital Herpes	4.1%
188	Corpus Luteum Cyst	3.8%
189	Ovarian Cysts	3.8%
190	Azotemia	3.8%
191	Anovulation	3.7%
192	Menorrhagia	3.7%
193	Albuminuria	3.7%
194	Hemoglobinuria	3.7%
195	Hypertension, Renovascular	3.7%
196	Premature Menopause	3.7%
197	Urge Incontinence	3.7%
198	Glomerulonephritis, Membranoproliferative	3.7%
199	Glycosuria, Renal	3.7%
200	Polycystic Ovary Syndrome	3.5%
201	Enuresis	3.4%
202	Gonadal Dysgenesis	3.3%
203	Adrenogenital Syndrome	3.3%
204	Ovotesticular Disorders of Sex Development	3.3%
205	Nephroblastoma	3.3%
206	Hyperandrogenism	3.2%
207	Denys-Drash Syndrome	3.2%
208	Polycystic Kidney Diseases	3%
209	Diurnal Enuresis	3%
210	Renal Aminoacidurias	3%
211	Fanconi Syndrome	3%
212	Pseudohypoaldosteronism	3%
213	Liddle Syndrome	3%
214	Hemolytic-Uremic Syndrome	2.9%
215	Anti-Glomerular Basement Membrane Disease	2.8%
216	Lupus Nephritis	2.8%
217	Polycystic Kidney, Autosomal Dominant	2.8%
218	Cystinuria	2.8%
219	AIDS-Associated Nephropathy	2.8%
220	Atypical Hemolytic Uremic Syndrome	2.8%
221	Chlamydia Infections	2.5%
222	Gonorrhea	2.5%
223	Renal tubular acidosis	2.5%
224	Lymphogranuloma Venereum	2.3%
225	Kallmann Syndrome	2.1%
226	Syphilis	2.1%
227	Turner Syndrome	2.1%
228	Renal Osteodystrophy	2%
229	Renal rickets	2%
230	Hyperphosphaturia	1.8%
231	Klinefelter Syndrome	1.8%
232	Zellweger Syndrome	1.5%
233	Familial Hypophosphatemic Rickets	1%

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