MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Nephrosis

(UMLS:C0027720)

Definition:: Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.
UMLS ID:: C0027720
MeSH ID:: D009401

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.419.630

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.419.630

Synonym(s)

Nephrosis

NEPHROSIS

Nephrosis, NOS

nephroses

nephrosis

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Acetohexamide	473209	CTD
2	Auranofin	104418	CTD
3	CGS 26303	11078415	CTD
4	Chlorpropamide	473209	CTD
5	Cyclophosphamide	4961747	CTD
6	Daunorubicin	View details 873414 1895548 2072310 2263029 2408437 2444108 3599547 4029807 4130907 4454746 4654712 4654713 4717736 5431221 6648960 7302360 7637207 8450912 8501853 9849860 10591482 10592367 12030316	CTD
7	Diatrizoate		SIDER
8	Diethylnitrosamine	16257853	CTD
9	Dilazep	9824428	CTD
10	Dipyridamole	9824428	CTD
11	Doxorubicin	View details 1565188 1586478 1658168 2161275 2340227 2483554 2559236 3054313 3107051 3784288 4038407 6195386 6632777 7731104 7900854 7977444 8139738 8583697 9102927 9334259 9406656 10412735 10598677 10694226 11402726 11849387 11972865 11981059 14736955 15157388 16352916 16636307 16899518 16959826 17061561 18791746 19149925 19225054 19459743 19889873 20299353	CTD
12	Edetic Acid	4982032	CTD
13	Felbamate		SIDER
14	Fenoprofen		SIDER
15	Furosemide	2254589	CTD
16	Gabapentin		SIDER
17	Gold Sodium Thiomalate	104418	CTD
18	Griseofulvin		SIDER
19	Hydrochlorothiazide	2254588	CTD
20	Indomethacin	6618773	CTD
21	Iohexol	1967501	CTD
22	Iopamidol		SIDER
23	Lisinopril	9165371	CTD
24	Mannitol	5415710 7003672	CTD SIDER
25	Mephenytoin		SIDER
26	Ofloxacin		SIDER
27	Omeprazole		SIDER
28	Oxytetracycline	8905581	CTD
29	Paraldehyde		SIDER
30	Pergolide		SIDER
31	Phenylephrine	10406839	CTD
32	Prednisone	4961747	CTD
33	Pregabalin		SIDER
34	Probucol	8583697	CTD
35	Puromycin Aminonucleoside	View details 839733 933467 1186127 1328752 1375300 1415478 1418851 1479717 1614035 1744988 1762292 1797743 1990206 2046802 2051647 2058701 2156648 2183627 2268473 2273594 2372813 2441105 2443012 2945356 3107051 3301049 3412819 3450901 3538253 3572200 3669494 3789094 3794548 3898001 3948917 6358456 6389977 6438895 6618773 7056851 7321525 7595070 7671567 7752581 7756592 7952147 8072247 8212539 8289993 8384958 8400078 8413769 8446257 8485924 8497129 8548034 8648930 8773353 8780404 8822086 8887289 8918620 8919236 9027795 9165371 9175058 9250166 9279205 9294829 9327748 9507238 9527400 9732237 9824428 10226349 10394110 10409307 10468195 10510332 10721075 10845833 10867541 10972674 11058564 11078415 11150858 11170791 11181809 11274237 11509803 11576343 11936424 11961407 12032185 12374619 12386276 12402553 12660332 12709412 12813006 12836089 12845231 13677671 14559718 14714169 14738908 14966466 15031335 15113391 15149336 15197181 15363039 15590761 15684566 15740732 15829708 16014031 16079985 16152783 16267158 16396944 16410268 16418842 16452496 16574160 16609681 16711654 17577743 17599817 18256598 18367650 18367845 18509322 18541230 18725544 19079321 19194550 19264907 19297354 19338138 19443634 19509464 19955829 20071462 20540862 20588063 25096716	CTD
36	Puromycin	9849860	CTD
37	Silver		SIDER
38	Sodium		SIDER
39	Sucrose	18295066	CTD
40	Sulfadiazine		SIDER
41	Sulfamethoxazole		SIDER
42	Sulfasalazine		SIDER
43	Tacrolimus	1375300	CTD
44	Thromboxane B2	4038407	CTD
45	Tolazamide	473209	CTD
46	Tolbutamide	473209	CTD
47	Tretinoin	12660332	CTD
48	Trimethadione	4961747	CTD SIDER
49	Vitamin A	12660332	CTD
50	Voriconazole		SIDER
51	beta-myrcene	21415873	CTD
52	cevimeline		SIDER
53	clorophene	3803756	CTD
54	liposomal amphotericin B		SIDER
55	mancozeb	12237977 12425114	CTD
56	maxacalcitol	19297354	CTD
57	triethyl phosphine gold	104418	CTD
58	turmeric extract	19459743	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hydronephrosis	47.5%
2	Hyperoxaluria	47.5%
3	Kidney Cortex Necrosis	47.5%
4	Kidney Papillary Necrosis	47.5%
5	Nephritis	47.5%
6	Nephrosclerosis	47.5%
7	Perinephritis	47.5%
8	Kidney Failure	47.5%
9	Uremia	47.5%
10	Oxalosis	47.5%
11	Renal Insufficiency	47.5%
12	Anuria	45.9%
13	Nephrolithiasis	45.9%
14	Diabetes Insipidus	38.7%
15	Hepatorenal Syndrome	38.7%
16	Pyelonephritis	38.7%
17	Diabetic Nephropathy	38.2%
18	Renal hypertension	38.2%
19	Renal Artery Obstruction	38.2%
20	Renal Artery Stenosis	38.2%
21	Nephrocalcinosis	37.9%
22	Glomerulonephritis	35.2%
23	Nephritis, Interstitial	35.2%
24	Pyelitis	35.2%
25	Pyonephrosis	35.2%
26	Nephrogenic Diabetes Insipidus	35.2%
27	Congenital Nephrogenic Diabetes Insipidus	35.2%
28	Acute kidney injury	35.2%
29	Tuberculosis, Renal	34.5%
30	Urinary Bladder Diseases	32.8%
31	Ureteral Diseases	32.8%
32	Urethral Diseases	32.8%
33	Urination Disorders	32.8%
34	Urolithiasis	32.8%
35	Kidney Neoplasm	31.8%
36	Pyelocystitis	29.9%
37	Kidney Calculi	29.5%
38	Balkan Nephropathy	29.2%
39	Focal glomerulosclerosis	29.2%
40	Kidney Failure, Chronic	29.2%
41	Azotemia	28.7%
42	Ureterolithiasis	28.4%
43	Hypertension, Renovascular	28.2%
44	Multicystic Dysplastic Kidney	27.7%
45	AIDS-Associated Nephropathy	27%
46	Urinary tract infection	26.5%
47	Bladder neck obstruction	24.7%
48	Glomerulonephritis, Membranoproliferative	24.5%
49	Polycystic Kidney Diseases	23.7%
50	Renal Aminoacidurias	23.5%
51	Fanconi Syndrome	23.5%
52	Pseudohypoaldosteronism	23.5%
53	Liddle Syndrome	23.5%
54	Hemolytic-Uremic Syndrome	23.4%
55	Glycosuria, Renal	22.6%
56	Cystitis	21.3%
57	Ureteral obstruction	21.3%
58	Ureterocele	21.3%
59	Urethral Obstruction	21.3%
60	Urethritis	21.3%
61	Vesico-Ureteral Reflux	21.3%
62	Urinary Retention	21.3%
63	Ureteral Calculi	20.9%
64	Renal Osteodystrophy	20.9%
65	Renal rickets	20.9%
66	Mesoblastic Nephroma	20.6%
67	Renal Cell Carcinoma	20.5%
68	Papillary Renal Cell Carcinoma	20.5%
69	Renal tubular acidosis	20.1%
70	Anti-Glomerular Basement Membrane Disease	19.9%
71	Lupus Nephritis	19.7%
72	Bladder Exstrophy	19.5%
73	Epispadias	19.5%
74	Polycystic Kidney, Autosomal Dominant	19.5%
75	Cystinuria	19.4%
76	Atypical Hemolytic Uremic Syndrome	19.3%
77	Urogenital Abnormalities	17.7%
78	Bacteriuria	17.1%
79	Glycosuria	17.1%
80	Hematuria	17.1%
81	Oliguria	17.1%
82	Polyuria	17.1%
83	Proteinuria	17.1%
84	Pyuria	17.1%
85	Urinary Calculi	17.1%
86	Cystocele	17%
87	Urinary Incontinence	17%
88	Urinary Bladder Fistula	16.8%
89	Bladder Neoplasm	16.8%
90	Ureteral Neoplasms	16.8%
91	Urethral Neoplasms	16.8%
92	Nephroblastoma	16.7%
93	Zellweger Syndrome	15.8%
94	Urethral Stenosis	15.8%
95	Urethral stricture	15.8%
96	Hyperphosphaturia	15.6%
97	Enuresis	14.4%
98	Albuminuria	12.6%
99	Hemoglobinuria	12.6%
100	Infertility	12.6%
101	Urge Incontinence	12.6%
102	Genital Diseases, Male	11.8%
103	Denys-Drash Syndrome	11.5%
104	Hypospadias	10.6%
105	Pregnancy Complications	10.6%
106	Diurnal Enuresis	10.6%
107	Urologic Neoplasms	10.1%
108	Horseshoe Kidney	10.1%
109	Endometriosis	9.9%
110	Uterine Diseases	9.9%
111	Vaginal Diseases	9.9%
112	Vulvar Diseases	9.9%
113	Endometrioma	9.9%
114	Vesicovaginal Fistula	8.9%
115	Sexually Transmitted Diseases	8.8%
116	Endometritis	8.5%
117	Hermaphroditism	8.5%
118	Disorders of Sex Development	8.5%
119	Genital Herpes	8.3%
120	Familial Hypophosphatemic Rickets	8.2%
121	Genital Neoplasms, Male	8.2%
122	Uterine Neoplasms	7.8%
123	Vaginal Neoplasms	7.8%
124	Vulvar Neoplasms	7.8%
125	Uterine Cancer	7.8%
126	Genital Neoplasms, Female	7.4%
127	Uterine Inversion	7.4%
128	Salpingitis	7.3%
129	Vulvovaginitis	7.3%
130	Fallopian Tube Neoplasms	6.8%
131	Epididymitis	6.7%
132	Penile Diseases	6.7%
133	Prostatic Diseases	6.7%
134	Spermatic Cord Torsion	6.7%
135	Hemospermia	6.7%
136	Testicular Hydrocele	6.7%
137	Dyspareunia	6.7%
138	Penile Neoplasms	6.6%
139	Prostatic Neoplasms	6.6%
140	Endometrial Hyperplasia	6.5%
141	Pyometra	6.5%
142	Vaginitis	6.5%
143	Vulvitis	6.5%
144	Vaginal Discharge	6.5%
145	Vulvodynia	6.5%
146	Uterine Rupture	6%
147	Oophoritis	5.8%
148	Endometrial Neoplasms	5.8%
149	Polyhydramnios	5.6%
150	Obstetric Labor Complications	5.6%
151	Ectopic Pregnancy	5.6%
152	Pregnancy, Prolonged	5.6%
153	Puerperal Disorders	5.6%
154	Oligohydramnios	5.6%
155	Prenatal Injuries	5.6%
156	Cryptorchidism	5.6%
157	Gonadal Dysgenesis	5.5%
158	Adrenogenital Syndrome	5.5%
159	Ovotesticular Disorders of Sex Development	5.5%
160	Uterine Cervical Incompetence	5.3%
161	Testicular Diseases	5.1%
162	Varicocele	5.1%
163	Spermatocele	5%
164	Ovarian Diseases	5%
165	ovarian neoplasm	5%
166	Abruptio Placentae	5%
167	Placenta Accreta	5%
168	Adnexitis	4.9%
169	Pruritus Vulvae	4.9%
170	Uterine hemorrhage	4.9%
171	Vaginal Fistula	4.9%
172	Pelvic Inflammatory Disease	4.9%
173	Uterine Prolapse	4.9%
174	Vaginal Prolapse	4.9%
175	Uterine Cervicitis	4.9%
176	Leukorrhea	4.9%
177	Parametritis	4.9%
178	Candidiasis, Vulvovaginal	4.9%
179	Prostatic Neoplasms, Castration-Resistant	4.9%
180	Hyperandrogenism	4.8%
181	Carcinoma, Endometrioid	4.8%
182	Chorioamnionitis	4.4%
183	Fetal Diseases	4.4%
184	Pregnancy Complications, Cardiovascular	4.4%
185	Pregnancy Complications, Neoplastic	4.4%
186	Balanitis	4.4%
187	Benign prostatic hypertrophy	4.4%
188	Phimosis	4.4%
189	Priapism	4.4%
190	prostatitis	4.4%
191	Prostatic Adenoma	4.4%
192	Benign Prostatic Hyperplasia	4.4%
193	Prostatic Hypertrophy	4.4%
194	Prostatic Hyperplasia	4.4%
195	Pregnancy Complications, Hematologic	4.3%
196	Pregnancy Complications, Infectious	4.3%
197	Fetal Death	4.2%
198	Perinatal death	4.2%
199	Morning Sickness	4.2%
200	Puerperal Infection	4%
201	Postpartum Hemorrhage	3.9%
202	Bacterial Vaginosis	3.7%
203	Trichomonas Vaginitis	3.7%
204	Uterine Perforation	3.7%
205	Ovarian Hyperstimulation Syndrome	3.7%
206	Metrorrhagia	3.6%
207	Endometrial Stromal Sarcoma	3.6%
208	Chlamydia Infections	3.5%
209	Gonorrhea	3.5%
210	Gestational Diabetes	3.4%
211	Premature Ejaculation	3.4%
212	Erectile dysfunction	3.4%
213	granulosa cell tumor	3.3%
214	Carcinoma, Ovarian Epithelial	3.3%
215	Testicular Neoplasms	3.3%
216	Orchitis	3.3%
217	Abortion, Habitual	3.3%
218	Dystocia	3.3%
219	Eclampsia	3.3%
220	Fetal Membranes, Premature Rupture	3.3%
221	Placental Insufficiency	3.3%
222	Pre-Eclampsia	3.3%
223	Prenatal Exposure Delayed Effects	3.3%
224	HELLP Syndrome	3.3%
225	Placenta, Retained	3.3%
226	Azoospermia	3.3%
227	Oligospermia	3.3%
228	Impotence, Vasculogenic	3.3%
229	Asthenozoospermia	3.3%
230	Teratozoospermia	3.3%
231	Aspermia	3.3%
232	Turner Syndrome	3.2%
233	Kallmann Syndrome	3.1%
234	Syphilis	3%
235	Corpus Luteum Cyst	3%
236	Ovarian Cysts	3%
237	Anovulation	2.9%
238	Menorrhagia	2.9%
239	Premature Menopause	2.9%
240	Lymphogranuloma Venereum	2.9%
241	Klinefelter Syndrome	2.7%
242	Abortion, Veterinary	2.6%
243	Pregnancy Complications, Parasitic	2.6%
244	Lactation Disorder	2.5%
245	Mastitis	2.5%
246	Depression, Postpartum	2.5%
247	Embryo Loss	2.5%
248	Fetal Resorption	2.5%
249	Hyperemesis Gravidarum	2.4%
250	Polycystic Ovary Syndrome	2.4%
251	Premature Birth	2.2%
252	Fetal Growth Retardation	2%
253	Trophoblastic Neoplasms	2%
254	Embolism, Amniotic Fluid	2%
255	Fetal Hypoxia	2%
256	Fetal Alcohol Spectrum Disorders	2%
257	Breech Presentation	2%
258	Stillbirth	2%
259	Leydig Cell Tumor	1.8%
260	Galactorrhea	1.6%
261	Meconium Aspiration Syndrome	1.5%
262	Choriocarcinoma	1.1%
263	Hydatidiform Mole	1%
264	Hydrops Fetalis	0.7%

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