MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Bladder neck obstruction

(UMLS:C0005694)

Definition:: Blocked urine flow through the bladder neck, the narrow internal urethral opening at the base of the URINARY BLADDER. Narrowing or strictures of the URETHRA can be congenital or acquired. It is often observed in males with enlarged PROSTATE glands.
UMLS ID:: C0005694
MeSH ID:: D001748

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.767.700.962|C12.777.829.760

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.767.700.850|C13.351.968.829.601

Synonym(s)

Bladder neck obstruction

BLADDER NECK URINARY OBSTRUCTION

BLADDER URINARY OBSTRUCTION

BNO - Bladder neck obstruction

Bladder Obstruction

Bladder Outlet Obstruction

Bladder neck obstruction, NOS

Bladder obstruction

Bladder outlet obstruction

10.

Bladder-neck obstruction

11.

Obstruction of bladder outlet

12.

Obstruction;bladder neck

13.

Urinary Outlet Obstruction

14.

Vesicourethral orifice obstruction

15.

Vesicourethral orifice obstruction, NOS

16.

bladder neck obstruction

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Finasteride	FAERS: 5	US FAERS
2	Tiotropium Bromide	FAERS: 5	US FAERS
3	Ketamine	FAERS: 4	US FAERS
4	rofecoxib	FAERS: 4	OFFSIDES US FAERS
5	Solifenacin Succinate	FAERS: 2	US FAERS
6	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1	US FAERS
7	Albuterol	FAERS: 1	US FAERS
8	Clopidogrel	FAERS: 1	US FAERS
9	Estrogens, Conjugated (USP)	FAERS: 1	US FAERS
10	Imatinib Mesylate	FAERS: 1	US FAERS
11	Lenalidomide	FAERS: 1	OFFSIDES US FAERS
12	Sildenafil Citrate	FAERS: 1	OFFSIDES US FAERS
13	Valsartan	FAERS: 1	US FAERS
14	Acetaminophen		SIDER
15	Aclidinium		SIDER
16	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination		OFFSIDES
17	Aspirin		OFFSIDES
18	Bisacodyl		OFFSIDES
19	Calcium Chloride		OFFSIDES
20	Calcium Citrate		OFFSIDES
21	Capecitabine		OFFSIDES
22	Carisoprodol		OFFSIDES
23	Celecoxib		OFFSIDES
24	Cilostazol		OFFSIDES
25	Clozapine		OFFSIDES
26	Donepezil	Canada Vigilance: 1	Canada Vigilance
27	Dutasteride		OFFSIDES
28	Erythromycin		OFFSIDES
29	Etoricoxib		OFFSIDES
30	Felodipine		OFFSIDES
31	Fusidic Acid		OFFSIDES
32	Goserelin		OFFSIDES
33	Ketoconazole		OFFSIDES
34	Labetalol		OFFSIDES
35	Lapatinib		OFFSIDES
36	Leuprolide		OFFSIDES
37	Meperidine		OFFSIDES
38	Methadone		OFFSIDES
39	Nadolol		OFFSIDES
40	Nalbuphine		OFFSIDES
41	Nitrofurantoin		OFFSIDES
42	Nortriptyline		OFFSIDES
43	Olanzapine		OFFSIDES
44	Pamidronate		OFFSIDES
45	Penicillins		OFFSIDES
46	Quinidine		OFFSIDES
47	Rivastigmine		OFFSIDES
48	Sertraline		OFFSIDES
49	Sirolimus		OFFSIDES
50	Temozolomide		OFFSIDES
51	Terazosin		OFFSIDES
52	Tetracycline		OFFSIDES
53	Thalidomide		OFFSIDES
54	Tiotropium Bromide		SIDER
55	Triptorelin Pamoate		SIDER
56	Zoledronic Acid		OFFSIDES
57	alfuzosin		OFFSIDES
58	bicalutamide		OFFSIDES
59	dexamethasone acetate		OFFSIDES
60	isosorbide-5-mononitrate		OFFSIDES
61	olsalazine		OFFSIDES
62	samarium Sm-153 lexidronam		OFFSIDES
63	trandolapril		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Urethral Stenosis	43.3%
2	Urethral stricture	43.3%
3	Cystitis	42%
4	Vesico-Ureteral Reflux	42%
5	Kidney Diseases	39.4%
6	Ureteral Diseases	39.4%
7	Urination Disorders	39.4%
8	Urolithiasis	39.4%
9	Bladder Exstrophy	38.5%
10	Urethritis	37.7%
11	Anuria	37.1%
12	Ureterolithiasis	37.1%
13	Nephrolithiasis	37.1%
14	Cystocele	36%
15	Epispadias	35.6%
16	Urinary Bladder Fistula	34.4%
17	Bladder Neoplasm	34.4%
18	Urinary tract infection	34.1%
19	Pyelocystitis	33.1%
20	Urethral Neoplasms	31.5%
21	Kidney Calculi	28.5%
22	Ureteral Calculi	28.5%
23	Tuberculosis, Renal	26.6%
24	Hydronephrosis	24.7%
25	Hyperoxaluria	24.7%
26	Kidney Cortex Necrosis	24.7%
27	Kidney Papillary Necrosis	24.7%
28	Nephritis	24.7%
29	Nephrosclerosis	24.7%
30	Nephrosis	24.7%
31	Perinephritis	24.7%
32	Kidney Failure	24.7%
33	Uremia	24.7%
34	Ureteral obstruction	24.7%
35	Ureterocele	24.7%
36	Urinary Retention	24.7%
37	Oxalosis	24.7%
38	Renal Insufficiency	24.7%
39	Urogenital Abnormalities	23.3%
40	Kidney Neoplasm	22.8%
41	Ureteral Neoplasms	22.8%
42	Multicystic Dysplastic Kidney	21.9%
43	Urethral Diseases	21.5%
44	Diabetes Insipidus	21.4%
45	Hepatorenal Syndrome	21.4%
46	Bacteriuria	21.2%
47	Diabetic Nephropathy	21.2%
48	Glycosuria	21.2%
49	Hematuria	21.2%
50	Renal hypertension	21.2%
51	Oliguria	21.2%
52	Polyuria	21.2%
53	Proteinuria	21.2%
54	Pyuria	21.2%
55	Renal Artery Obstruction	21.2%
56	Renal Artery Stenosis	21.2%
57	Urinary Calculi	21.2%
58	Nephrocalcinosis	21.1%
59	Urinary Incontinence	21.1%
60	Pyelonephritis	20.8%
61	Glycosuria, Renal	19%
62	Enuresis	18.8%
63	Urinary Bladder Diseases	17.9%
64	Glomerulonephritis	17.5%
65	Nephritis, Interstitial	17.5%
66	Lipoid nephrosis	17.5%
67	Nephrotic Syndrome	17.5%
68	Pyelitis	17.5%
69	Pyonephrosis	17.5%
70	Nephrogenic Diabetes Insipidus	17.5%
71	Congenital Nephrogenic Diabetes Insipidus	17.5%
72	Acute kidney injury	17.5%
73	AIDS-Associated Nephropathy	16.4%
74	Vesicovaginal Fistula	15.9%
75	Bladder neck obstruction	15.8%
76	Azotemia	15.2%
77	Infertility	15.2%
78	Albuminuria	15%
79	Hemoglobinuria	15%
80	Hypertension, Renovascular	15%
81	Urge Incontinence	14.9%
82	Mesoblastic Nephroma	14.5%
83	Renal Cell Carcinoma	14.4%
84	Papillary Renal Cell Carcinoma	14.4%
85	Hypospadias	14.3%
86	Urethral Obstruction	14.1%
87	Balkan Nephropathy	13.9%
88	Focal glomerulosclerosis	13.9%
89	Kidney Failure, Chronic	13.9%
90	Renal Osteodystrophy	13.4%
91	Renal rickets	13.4%
92	Polycystic Kidney Diseases	13.2%
93	Diurnal Enuresis	13.2%
94	Renal Aminoacidurias	13.1%
95	Fanconi Syndrome	13.1%
96	Pseudohypoaldosteronism	13.1%
97	Liddle Syndrome	13.1%
98	Hemolytic-Uremic Syndrome	13.1%
99	Urologic Neoplasms	13%
100	Horseshoe Kidney	13%
101	Genital Diseases, Male	12.9%
102	Glomerulonephritis, Membranoproliferative	12.3%
103	Nephroblastoma	12.2%
104	Pregnancy Complications	11.9%
105	Sexually Transmitted Diseases	11.8%
106	Renal tubular acidosis	11.6%
107	Hermaphroditism	11.5%
108	Disorders of Sex Development	11.5%
109	Genital Herpes	11.3%
110	Endometriosis	10.7%
111	Uterine Diseases	10.7%
112	Vaginal Diseases	10.7%
113	Vulvar Diseases	10.7%
114	Endometrioma	10.7%
115	Anti-Glomerular Basement Membrane Disease	10.6%
116	Zellweger Syndrome	10.6%
117	Lupus Nephritis	10.5%
118	Genital Neoplasms, Male	10.5%
119	Polycystic Kidney, Autosomal Dominant	10.5%
120	Cystinuria	10.4%
121	Atypical Hemolytic Uremic Syndrome	10.4%
122	Denys-Drash Syndrome	9.7%
123	Uterine Neoplasms	9.7%
124	Vaginal Neoplasms	9.7%
125	Vulvar Neoplasms	9.7%
126	Uterine Cancer	9.7%
127	Endometritis	9.7%
128	Hyperphosphaturia	9.5%
129	Genital Neoplasms, Female	9%
130	Uterine Inversion	8.7%
131	Penile Neoplasms	8.6%
132	Prostatic Neoplasms	8.6%
133	Fallopian Tube Neoplasms	8.3%
134	Dyspareunia	8.2%
135	Salpingitis	8%
136	Vulvovaginitis	8%
137	Uterine Rupture	7.5%
138	Cryptorchidism	7.5%
139	Epididymitis	7.3%
140	Penile Diseases	7.3%
141	Prostatic Diseases	7.3%
142	Spermatic Cord Torsion	7.3%
143	Hemospermia	7.3%
144	Testicular Hydrocele	7.3%
145	Gonadal Dysgenesis	7.1%
146	Adrenogenital Syndrome	7.1%
147	Ovotesticular Disorders of Sex Development	7.1%
148	Oophoritis	6.9%
149	Endometrial Neoplasms	6.9%
150	Endometrial Hyperplasia	6.8%
151	Pyometra	6.8%
152	Vaginitis	6.8%
153	Vulvitis	6.8%
154	Vaginal Discharge	6.8%
155	Vulvodynia	6.8%
156	Hyperandrogenism	6.7%
157	ovarian neoplasm	6.6%
158	Polyhydramnios	6.3%
159	Obstetric Labor Complications	6.3%
160	Ectopic Pregnancy	6.3%
161	Pregnancy, Prolonged	6.3%
162	Puerperal Disorders	6.3%
163	Oligohydramnios	6.3%
164	Prenatal Injuries	6.3%
165	Carcinoma, Endometrioid	6.2%
166	Testicular Diseases	6.1%
167	Varicocele	6.1%
168	Spermatocele	6.1%
169	Prostatic Neoplasms, Castration-Resistant	6%
170	Abruptio Placentae	6%
171	Placenta Accreta	6%
172	Chorioamnionitis	6%
173	Uterine Cervical Incompetence	5.9%
174	Ovarian Diseases	5.8%
175	Adnexitis	5.7%
176	Pruritus Vulvae	5.7%
177	Uterine hemorrhage	5.7%
178	Vaginal Fistula	5.7%
179	Pelvic Inflammatory Disease	5.7%
180	Uterine Prolapse	5.7%
181	Vaginal Prolapse	5.7%
182	Candidiasis, Vulvovaginal	5.5%
183	Fetal Diseases	5.4%
184	Pregnancy Complications, Cardiovascular	5.4%
185	Pregnancy Complications, Neoplastic	5.4%
186	Pregnancy Complications, Hematologic	5.3%
187	Pregnancy Complications, Infectious	5.3%
188	Fetal Death	5.2%
189	Perinatal death	5.2%
190	Morning Sickness	5.2%
191	Familial Hypophosphatemic Rickets	5.2%
192	Puerperal Infection	5.2%
193	Postpartum Hemorrhage	5.1%
194	Uterine Cervicitis	4.8%
195	Leukorrhea	4.8%
196	Parametritis	4.8%
197	Turner Syndrome	4.7%
198	Testicular Neoplasms	4.6%
199	Balanitis	4.6%
200	Benign prostatic hypertrophy	4.6%
201	Phimosis	4.6%
202	Priapism	4.6%
203	prostatitis	4.6%
204	Prostatic Adenoma	4.6%
205	Benign Prostatic Hyperplasia	4.6%
206	Prostatic Hypertrophy	4.6%
207	Prostatic Hyperplasia	4.6%
208	Gestational Diabetes	4.5%
209	Chlamydia Infections	4.5%
210	Gonorrhea	4.5%
211	granulosa cell tumor	4.4%
212	Carcinoma, Ovarian Epithelial	4.4%
213	Endometrial Stromal Sarcoma	4.2%
214	Bacterial Vaginosis	4.1%
215	Kallmann Syndrome	4.1%
216	Trichomonas Vaginitis	4.1%
217	Uterine Perforation	4.1%
218	Ovarian Hyperstimulation Syndrome	4.1%
219	Syphilis	4%
220	Metrorrhagia	4%
221	Premature Ejaculation	3.9%
222	Erectile dysfunction	3.9%
223	Orchitis	3.8%
224	Klinefelter Syndrome	3.7%
225	Abortion, Habitual	3.6%
226	Dystocia	3.6%
227	Eclampsia	3.6%
228	Fetal Membranes, Premature Rupture	3.6%
229	Placental Insufficiency	3.6%
230	Pre-Eclampsia	3.6%
231	Prenatal Exposure Delayed Effects	3.6%
232	HELLP Syndrome	3.6%
233	Placenta, Retained	3.6%
234	Lymphogranuloma Venereum	3.6%
235	Corpus Luteum Cyst	3.5%
236	Ovarian Cysts	3.5%
237	Anovulation	3.5%
238	Menorrhagia	3.5%
239	Premature Menopause	3.4%
240	Azoospermia	3.2%
241	Oligospermia	3.2%
242	Impotence, Vasculogenic	3.2%
243	Asthenozoospermia	3.2%
244	Teratozoospermia	3.2%
245	Aspermia	3.2%
246	Abortion, Veterinary	3.1%
247	Pregnancy Complications, Parasitic	3.1%
248	Lactation Disorder	3%
249	Mastitis	3%
250	Depression, Postpartum	3%
251	Embryo Loss	3%
252	Fetal Resorption	3%
253	Hyperemesis Gravidarum	3%
254	Polycystic Ovary Syndrome	2.8%
255	Fetal Growth Retardation	2.6%
256	Trophoblastic Neoplasms	2.6%
257	Embolism, Amniotic Fluid	2.6%
258	Fetal Hypoxia	2.6%
259	Fetal Alcohol Spectrum Disorders	2.6%
260	Breech Presentation	2.6%
261	Stillbirth	2.5%
262	Leydig Cell Tumor	2.3%
263	Premature Birth	2.3%
264	Meconium Aspiration Syndrome	2.1%
265	Galactorrhea	1.9%
266	Choriocarcinoma	1.4%
267	Hydatidiform Mole	1.1%
268	Hydrops Fetalis	1%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120238