MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Vesico-Ureteral Reflux

(UMLS:C0042580)

Definition:: Retrograde flow of urine from the URINARY BLADDER into the URETER. This is often due to incompetence of the vesicoureteral valve leading to ascending bacterial infection into the KIDNEY.
UMLS ID:: C0042580
MeSH ID:: D014718

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.829.920

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.829.920

Synonym(s)

Vesico-Ureteral Reflux

Reflux;ureteric

Ureteral reflux

Ureteric reflux

VESICOURETER REFLUX

VUR - Vesicoureteral Reflux

VUR - Vesicoureteric reflux

Vesico-ureteral reflux

Vesico-ureteric reflux

10.

Vesicoureteral Reflux

11.

Vesicoureteral reflux

12.

Vesicoureteral-reflux, unspecified

13.

Vesicoureteric Reflux

14.

Vesicoureteric reflux

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Cyclophosphamide		6887415	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Cystitis	47.5%
2	Bladder neck obstruction	42%
3	Cystocele	37.9%
4	Bladder Exstrophy	34.8%
5	Kidney Diseases	32.8%
6	Ureteral Diseases	32.8%
7	Urethral Diseases	32.8%
8	Urination Disorders	32.8%
9	Urolithiasis	32.8%
10	Pyelocystitis	32%
11	Urinary Bladder Fistula	31.8%
12	Bladder Neoplasm	31.8%
13	Anuria	28.4%
14	Ureterolithiasis	28.4%
15	Nephrolithiasis	28.4%
16	Urinary tract infection	26.5%
17	Hydronephrosis	21.3%
18	Hyperoxaluria	21.3%
19	Kidney Cortex Necrosis	21.3%
20	Kidney Papillary Necrosis	21.3%
21	Nephritis	21.3%
22	Nephrosclerosis	21.3%
23	Nephrosis	21.3%
24	Perinephritis	21.3%
25	Kidney Failure	21.3%
26	Uremia	21.3%
27	Ureteral obstruction	21.3%
28	Ureterocele	21.3%
29	Urethral Obstruction	21.3%
30	Urethritis	21.3%
31	Urinary Retention	21.3%
32	Oxalosis	21.3%
33	Renal Insufficiency	21.3%
34	Kidney Calculi	20.9%
35	Ureteral Calculi	20.9%
36	Epispadias	19.5%
37	Tuberculosis, Renal	19.4%
38	Urogenital Abnormalities	17.7%
39	Diabetes Insipidus	17.3%
40	Hepatorenal Syndrome	17.3%
41	Pyelonephritis	17.3%
42	Bacteriuria	17.1%
43	Diabetic Nephropathy	17.1%
44	Glycosuria	17.1%
45	Hematuria	17.1%
46	Renal hypertension	17.1%
47	Oliguria	17.1%
48	Polyuria	17.1%
49	Proteinuria	17.1%
50	Pyuria	17.1%
51	Renal Artery Obstruction	17.1%
52	Renal Artery Stenosis	17.1%
53	Urinary Calculi	17.1%
54	Nephrocalcinosis	17%
55	Urinary Incontinence	17%
56	Kidney Neoplasm	16.8%
57	Ureteral Neoplasms	16.8%
58	Urethral Neoplasms	16.8%
59	Multicystic Dysplastic Kidney	16.3%
60	Glomerulonephritis	15.8%
61	Nephritis, Interstitial	15.8%
62	Lipoid nephrosis	15.8%
63	Nephrotic Syndrome	15.8%
64	Pyelitis	15.8%
65	Pyonephrosis	15.8%
66	Urethral Stenosis	15.8%
67	Nephrogenic Diabetes Insipidus	15.8%
68	Congenital Nephrogenic Diabetes Insipidus	15.8%
69	Acute kidney injury	15.8%
70	Urethral stricture	15.8%
71	Vesicovaginal Fistula	14.4%
72	Enuresis	14.4%
73	Glycosuria, Renal	14%
74	Balkan Nephropathy	13.1%
75	Focal glomerulosclerosis	13.1%
76	Kidney Failure, Chronic	13.1%
77	Azotemia	12.9%
78	Albuminuria	12.6%
79	Hemoglobinuria	12.6%
80	Hypertension, Renovascular	12.6%
81	Infertility	12.6%
82	Urge Incontinence	12.6%
83	AIDS-Associated Nephropathy	12.1%
84	Genital Diseases, Male	11.8%
85	Glomerulonephritis, Membranoproliferative	11%
86	Mesoblastic Nephroma	10.9%
87	Renal Cell Carcinoma	10.8%
88	Papillary Renal Cell Carcinoma	10.8%
89	Polycystic Kidney Diseases	10.6%
90	Hypospadias	10.6%
91	Pregnancy Complications	10.6%
92	Diurnal Enuresis	10.6%
93	Renal Aminoacidurias	10.5%
94	Fanconi Syndrome	10.5%
95	Pseudohypoaldosteronism	10.5%
96	Liddle Syndrome	10.5%
97	Hemolytic-Uremic Syndrome	10.5%
98	Urologic Neoplasms	10.1%
99	Horseshoe Kidney	10.1%
100	Endometriosis	9.9%
101	Uterine Diseases	9.9%
102	Vaginal Diseases	9.9%
103	Vulvar Diseases	9.9%
104	Endometrioma	9.9%
105	Renal Osteodystrophy	9.4%
106	Renal rickets	9.4%
107	Renal tubular acidosis	9%
108	Anti-Glomerular Basement Membrane Disease	8.9%
109	Nephroblastoma	8.8%
110	Lupus Nephritis	8.8%
111	Sexually Transmitted Diseases	8.8%
112	Polycystic Kidney, Autosomal Dominant	8.7%
113	Cystinuria	8.7%
114	Atypical Hemolytic Uremic Syndrome	8.7%
115	Endometritis	8.5%
116	Hermaphroditism	8.5%
117	Disorders of Sex Development	8.5%
118	Genital Herpes	8.3%
119	Genital Neoplasms, Male	8.2%
120	Uterine Neoplasms	7.8%
121	Vaginal Neoplasms	7.8%
122	Vulvar Neoplasms	7.8%
123	Uterine Cancer	7.8%
124	Genital Neoplasms, Female	7.4%
125	Uterine Inversion	7.4%
126	Salpingitis	7.3%
127	Vulvovaginitis	7.3%
128	Zellweger Syndrome	7.1%
129	Hyperphosphaturia	7%
130	Denys-Drash Syndrome	6.9%
131	Fallopian Tube Neoplasms	6.8%
132	Epididymitis	6.7%
133	Penile Diseases	6.7%
134	Prostatic Diseases	6.7%
135	Spermatic Cord Torsion	6.7%
136	Hemospermia	6.7%
137	Testicular Hydrocele	6.7%
138	Dyspareunia	6.7%
139	Penile Neoplasms	6.6%
140	Prostatic Neoplasms	6.6%
141	Endometrial Hyperplasia	6.5%
142	Pyometra	6.5%
143	Vaginitis	6.5%
144	Vulvitis	6.5%
145	Vaginal Discharge	6.5%
146	Vulvodynia	6.5%
147	Uterine Rupture	6%
148	Oophoritis	5.8%
149	Endometrial Neoplasms	5.8%
150	Polyhydramnios	5.6%
151	Obstetric Labor Complications	5.6%
152	Ectopic Pregnancy	5.6%
153	Pregnancy, Prolonged	5.6%
154	Puerperal Disorders	5.6%
155	Oligohydramnios	5.6%
156	Prenatal Injuries	5.6%
157	Cryptorchidism	5.6%
158	Gonadal Dysgenesis	5.5%
159	Adrenogenital Syndrome	5.5%
160	Ovotesticular Disorders of Sex Development	5.5%
161	Uterine Cervical Incompetence	5.3%
162	Testicular Diseases	5.1%
163	Varicocele	5.1%
164	Spermatocele	5%
165	Ovarian Diseases	5%
166	ovarian neoplasm	5%
167	Abruptio Placentae	5%
168	Placenta Accreta	5%
169	Adnexitis	4.9%
170	Pruritus Vulvae	4.9%
171	Uterine hemorrhage	4.9%
172	Vaginal Fistula	4.9%
173	Pelvic Inflammatory Disease	4.9%
174	Uterine Prolapse	4.9%
175	Vaginal Prolapse	4.9%
176	Uterine Cervicitis	4.9%
177	Leukorrhea	4.9%
178	Parametritis	4.9%
179	Candidiasis, Vulvovaginal	4.9%
180	Prostatic Neoplasms, Castration-Resistant	4.9%
181	Hyperandrogenism	4.8%
182	Carcinoma, Endometrioid	4.8%
183	Chorioamnionitis	4.4%
184	Fetal Diseases	4.4%
185	Pregnancy Complications, Cardiovascular	4.4%
186	Pregnancy Complications, Neoplastic	4.4%
187	Balanitis	4.4%
188	Benign prostatic hypertrophy	4.4%
189	Phimosis	4.4%
190	Priapism	4.4%
191	prostatitis	4.4%
192	Prostatic Adenoma	4.4%
193	Benign Prostatic Hyperplasia	4.4%
194	Prostatic Hypertrophy	4.4%
195	Prostatic Hyperplasia	4.4%
196	Pregnancy Complications, Hematologic	4.3%
197	Pregnancy Complications, Infectious	4.3%
198	Fetal Death	4.2%
199	Perinatal death	4.2%
200	Morning Sickness	4.2%
201	Puerperal Infection	4%
202	Postpartum Hemorrhage	3.9%
203	Bacterial Vaginosis	3.7%
204	Familial Hypophosphatemic Rickets	3.7%
205	Trichomonas Vaginitis	3.7%
206	Uterine Perforation	3.7%
207	Ovarian Hyperstimulation Syndrome	3.7%
208	Metrorrhagia	3.6%
209	Endometrial Stromal Sarcoma	3.6%
210	Chlamydia Infections	3.5%
211	Gonorrhea	3.5%
212	Gestational Diabetes	3.4%
213	Premature Ejaculation	3.4%
214	Erectile dysfunction	3.4%
215	granulosa cell tumor	3.3%
216	Carcinoma, Ovarian Epithelial	3.3%
217	Testicular Neoplasms	3.3%
218	Orchitis	3.3%
219	Abortion, Habitual	3.3%
220	Dystocia	3.3%
221	Eclampsia	3.3%
222	Fetal Membranes, Premature Rupture	3.3%
223	Placental Insufficiency	3.3%
224	Pre-Eclampsia	3.3%
225	Prenatal Exposure Delayed Effects	3.3%
226	HELLP Syndrome	3.3%
227	Placenta, Retained	3.3%
228	Azoospermia	3.3%
229	Oligospermia	3.3%
230	Impotence, Vasculogenic	3.3%
231	Asthenozoospermia	3.3%
232	Teratozoospermia	3.3%
233	Aspermia	3.3%
234	Turner Syndrome	3.2%
235	Kallmann Syndrome	3.1%
236	Syphilis	3%
237	Corpus Luteum Cyst	3%
238	Ovarian Cysts	3%
239	Anovulation	2.9%
240	Menorrhagia	2.9%
241	Premature Menopause	2.9%
242	Lymphogranuloma Venereum	2.9%
243	Klinefelter Syndrome	2.7%
244	Abortion, Veterinary	2.6%
245	Pregnancy Complications, Parasitic	2.6%
246	Lactation Disorder	2.5%
247	Mastitis	2.5%
248	Depression, Postpartum	2.5%
249	Embryo Loss	2.5%
250	Fetal Resorption	2.5%
251	Hyperemesis Gravidarum	2.4%
252	Polycystic Ovary Syndrome	2.4%
253	Premature Birth	2.2%
254	Fetal Growth Retardation	2%
255	Trophoblastic Neoplasms	2%
256	Embolism, Amniotic Fluid	2%
257	Fetal Hypoxia	2%
258	Fetal Alcohol Spectrum Disorders	2%
259	Breech Presentation	2%
260	Stillbirth	2%
261	Leydig Cell Tumor	1.8%
262	Galactorrhea	1.6%
263	Meconium Aspiration Syndrome	1.5%
264	Choriocarcinoma	1.1%
265	Hydatidiform Mole	1%
266	Hydrops Fetalis	0.7%

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