MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Cystocele

(UMLS:C0010695)

Definition:: A HERNIA-like condition in which the weakened pelvic muscles cause the URINARY BLADDER to drop from its normal position. Fallen urinary bladder is more common in females with the bladder dropping into the VAGINA and less common in males with the bladder dropping into the SCROTUM.
UMLS ID:: C0010695
MeSH ID:: D052858

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.829.707

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.829.508

Classification 3:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.300.842.624.249

Synonym(s)

Cystocele

CYSTOCELE

Cystocele, NOS

Cystocoele

bladder cystocele

bladder hernia

cystocele

cystocele bladder

cystoceles

10.

cystocoele

11.

hernia bladder

12.

vesical hernia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Alendronate	FAERS: 55		OFFSIDES US FAERS
2	rofecoxib	FAERS: 15		OFFSIDES US FAERS
3	Teriparatide	FAERS: 7		US FAERS
4	NuvaRing	FAERS: 4		US FAERS
5	Estradiol	FAERS: 3		OFFSIDES US FAERS
6	Fingolimod Hydrochloride	FAERS: 3		US FAERS
7	Ondansetron	FAERS: 3		US FAERS
8	Tolterodine Tartrate	FAERS: 3		US FAERS
9	Citalopram	FAERS: 2		US FAERS
10	Insulin Glargine	FAERS: 2		US FAERS
11	Oxycodone	FAERS: 2		US FAERS
12	acetaminophen, aspirin, caffeine drug combination	FAERS: 2		US FAERS
13	4-hydroxybutyric acid	FAERS: 1		US FAERS
14	Dabigatran	FAERS: 1		US FAERS
15	Deferasirox	FAERS: 1		US FAERS
16	Estrogens, Conjugated (USP)	FAERS: 1		OFFSIDES US FAERS
17	Exenatide	FAERS: 1		US FAERS
18	Norgestrel	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
19	Pamidronate	FAERS: 1		US FAERS
20	Phentermine	FAERS: 1		US FAERS
21	Raloxifene Hydrochloride	FAERS: 1		US FAERS
22	Sitagliptin Phosphate	FAERS: 1		US FAERS
23	Terbutaline	FAERS: 1		US FAERS
24	apixaban	FAERS: 1		US FAERS
25	eletriptan	FAERS: 1		US FAERS
26	olaparib	FAERS: 1		US FAERS
27	palbociclib	FAERS: 1		US FAERS
28	paricalcitol	FAERS: 1		US FAERS
29	rotigotine	FAERS: 1		US FAERS
30	teriflunomide	FAERS: 1		US FAERS
31	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride			OFFSIDES
32	5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydron;chloride			OFFSIDES
33	Acebutolol			OFFSIDES
34	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination			OFFSIDES
35	Atorvastatin			OFFSIDES
36	Azithromycin			OFFSIDES
37	Betaxolol			OFFSIDES
38	Bimatoprost			OFFSIDES
39	Bupropion			OFFSIDES
40	Calcium Carbonate			OFFSIDES
41	Capecitabine			OFFSIDES
42	Carisoprodol			OFFSIDES
43	Cetirizine			OFFSIDES
44	Chlorhexidine			OFFSIDES
45	Cimetidine			OFFSIDES
46	Ciprofloxacin			OFFSIDES
47	Clindamycin			OFFSIDES
48	Clotrimazole			OFFSIDES
49	Dermazin			OFFSIDES
50	Dexamethasone			OFFSIDES
51	Diclofenac			OFFSIDES
52	Etodolac			OFFSIDES
53	Famciclovir			OFFSIDES
54	Fludrocortisone			OFFSIDES
55	Flurazepam			OFFSIDES
56	Fulvestrant			OFFSIDES
57	Furosemide			OFFSIDES
58	Gatifloxacin			OFFSIDES
59	Glipizide			OFFSIDES
60	Hydromorphone			OFFSIDES
61	Ibuprofen			OFFSIDES
62	Imipramine			OFFSIDES
63	Ipratropium			OFFSIDES
64	Ketoprofen			OFFSIDES
65	Lasofoxifene			SIDER
66	Letrozole			OFFSIDES
67	Meloxicam			OFFSIDES
68	Memantine			OFFSIDES
69	Methocarbamol			OFFSIDES
70	Metoclopramide			OFFSIDES
71	Mirtazapine			OFFSIDES
72	Mupirocin			OFFSIDES
73	Nitrofurantoin			OFFSIDES
74	Nitrous Oxide			OFFSIDES
75	Omeprazole			OFFSIDES
76	Orphenadrine			OFFSIDES
77	Penicillin V			OFFSIDES
78	Phenazopyridine		5410400	CTD OFFSIDES
79	Progesterone			OFFSIDES
80	Promethazine			OFFSIDES
81	Raloxifene Hydrochloride			OFFSIDES
82	Rosiglitazone			OFFSIDES
83	Salmeterol Xinafoate			OFFSIDES
84	Salmeterol Xinafoate			OFFSIDES
85	Sertraline			OFFSIDES
86	Solifenacin Succinate			OFFSIDES
87	Sotalol			OFFSIDES
88	Sulfate			OFFSIDES
89	Tadalafil			OFFSIDES
90	Tamoxifen			OFFSIDES
91	Thalidomide			OFFSIDES
92	Tretinoin			OFFSIDES
93	Venlafaxine Hydrochloride			OFFSIDES
94	Vinorelbine			OFFSIDES
95	Vitamin E			OFFSIDES
96	Zoledronic Acid	Canada Vigilance: 1		Canada Vigilance OFFSIDES
97	benazepril			OFFSIDES
98	benzonatate			OFFSIDES
99	candesartan cilexetil			OFFSIDES
100	cefprozil			OFFSIDES
101	darifenacin			OFFSIDES
102	exemestane			OFFSIDES
103	hydrocodone tartrate, ibuprofen drug combination			OFFSIDES
104	mecobalamin			OFFSIDES
105	norgestimate, ethinyl estradiol drug combination			OFFSIDES
106	tegaserod			OFFSIDES
107	tegaserod			OFFSIDES
108	terconazole			OFFSIDES
109	zafirlukast			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Cystitis	37.9%
2	Vesico-Ureteral Reflux	37.9%
3	Bladder neck obstruction	36%
4	Bladder Exstrophy	30.3%
5	Urinary Bladder Fistula	30.2%
6	Bladder Neoplasm	27.8%
7	Pyelocystitis	27.4%
8	Kidney Diseases	26%
9	Ureteral Diseases	26%
10	Urethral Diseases	26%
11	Urination Disorders	26%
12	Urolithiasis	26%
13	Anuria	24.3%
14	Ureterolithiasis	24.3%
15	Nephrolithiasis	24.3%
16	Uterine Prolapse	23.4%
17	Vaginal Prolapse	23.4%
18	Urinary tract infection	21.9%
19	Kidney Calculi	20.8%
20	Ureteral Calculi	20.8%
21	Rectal Prolapse	19.5%
22	Urinary Calculi	19.1%
23	Epispadias	17%
24	Hydronephrosis	17%
25	Hyperoxaluria	17%
26	Kidney Cortex Necrosis	17%
27	Kidney Papillary Necrosis	17%
28	Nephritis	17%
29	Nephrosclerosis	17%
30	Nephrosis	17%
31	Perinephritis	17%
32	Kidney Failure	17%
33	Uremia	17%
34	Ureteral obstruction	17%
35	Ureterocele	17%
36	Urethral Obstruction	17%
37	Urethritis	17%
38	Urinary Retention	17%
39	Oxalosis	17%
40	Renal Insufficiency	17%
41	Tuberculosis, Renal	16.9%
42	Vesicovaginal Fistula	16.9%
43	Hematuria	15.8%
44	Oliguria	15.8%
45	Polyuria	15.8%
46	Proteinuria	15.8%
47	Urinary Incontinence	15.2%
48	Pyelonephritis	14.9%
49	Kidney Neoplasm	14.7%
50	Ureteral Neoplasms	14.7%
51	Urethral Neoplasms	14.7%
52	Urogenital Abnormalities	14.5%
53	Diabetes Insipidus	14.4%
54	Hepatorenal Syndrome	14.4%
55	Multicystic Dysplastic Kidney	14.2%
56	Bacteriuria	14.2%
57	Diabetic Nephropathy	14.2%
58	Glycosuria	14.2%
59	Renal hypertension	14.2%
60	Pyuria	14.2%
61	Renal Artery Obstruction	14.2%
62	Renal Artery Stenosis	14.2%
63	Nephrocalcinosis	14.1%
64	Azotemia	13.4%
65	Glomerulonephritis	12.6%
66	Nephritis, Interstitial	12.6%
67	Lipoid nephrosis	12.6%
68	Nephrotic Syndrome	12.6%
69	Pyelitis	12.6%
70	Pyonephrosis	12.6%
71	Urethral Stenosis	12.6%
72	Nephrogenic Diabetes Insipidus	12.6%
73	Congenital Nephrogenic Diabetes Insipidus	12.6%
74	Acute kidney injury	12.6%
75	Urethral stricture	12.6%
76	Glycosuria, Renal	12.6%
77	Calculi	12.5%
78	Hernia	12.5%
79	Hypertrophy	12.5%
80	Nails, Malformed	12.5%
81	polyps	12.5%
82	Rupture, Spontaneous	12.5%
83	Enterocele	12.5%
84	Atheroma	12.5%
85	Stenosis	12.5%
86	Facial asymmetry	12.5%
87	Plaque, Amyloid	12.5%
88	Plaque, Atherosclerotic	12.5%
89	Enuresis	12.3%
90	Albuminuria	11.6%
91	Hemoglobinuria	11.6%
92	Vascular Remodeling	11.4%
93	Urge Incontinence	11.3%
94	AIDS-Associated Nephropathy	10.6%
95	Hypertension, Renovascular	10.5%
96	Balkan Nephropathy	10.5%
97	Focal glomerulosclerosis	10.5%
98	Kidney Failure, Chronic	10.5%
99	Cyst	10.4%
100	Leukoplakia	10.1%
101	Airway Remodeling	10.1%
102	Infertility	10%
103	Spermatocele	10%
104	Ventricular Remodeling	10%
105	Alopecia	9.9%
106	Androgenetic Alopecia	9.9%
107	Vaginal Fistula	9.8%
108	Mesoblastic Nephroma	9.7%
109	Renal Cell Carcinoma	9.6%
110	Papillary Renal Cell Carcinoma	9.6%
111	Polycystic Kidney Diseases	9.1%
112	Glomerulonephritis, Membranoproliferative	9.1%
113	Diurnal Enuresis	9%
114	Hypospadias	9%
115	Renal Aminoacidurias	9%
116	Fanconi Syndrome	9%
117	Pseudohypoaldosteronism	9%
118	Liddle Syndrome	9%
119	Hemolytic-Uremic Syndrome	9%
120	Genital Diseases, Male	8.6%
121	Renal Osteodystrophy	8.4%
122	Renal rickets	8.4%
123	Urologic Neoplasms	8.3%
124	Horseshoe Kidney	8.3%
125	Diverticulum	8.2%
126	Diverticulosis	8.2%
127	Nephroblastoma	8%
128	Incisional hernia	7.9%
129	Renal tubular acidosis	7.9%
130	Pregnancy Complications	7.8%
131	Signs and Symptoms	7.8%
132	Anti-Glomerular Basement Membrane Disease	7.6%
133	Lupus Nephritis	7.5%
134	Polycystic Kidney, Autosomal Dominant	7.5%
135	Cystinuria	7.4%
136	Atypical Hemolytic Uremic Syndrome	7.4%
137	Sexually Transmitted Diseases	7.4%
138	Endometriosis	7.4%
139	Diaphragmatic Hernia	7.4%
140	Intestinal Polyps	7.4%
141	Splenomegaly	7.4%
142	Uterine Diseases	7.4%
143	Vaginal Diseases	7.4%
144	Vulvar Diseases	7.4%
145	Endometrioma	7.4%
146	Hermaphroditism	7.2%
147	Disorders of Sex Development	7.2%
148	Genital Herpes	7.1%
149	Endometritis	6.8%
150	Polydipsia	6.8%
151	Genital Neoplasms, Male	6.7%
152	Zellweger Syndrome	6.5%
153	Uterine Neoplasms	6.5%
154	Vaginal Neoplasms	6.5%
155	Vulvar Neoplasms	6.5%
156	Uterine Cancer	6.5%
157	Denys-Drash Syndrome	6.4%
158	Hyperphosphaturia	6.3%
159	Respiratory Tract Fistula	6.2%
160	Muscular Atrophy	6%
161	Cardiomegaly	6%
162	Hepatomegaly	6%
163	Parovarian Cyst	6%
164	Oral Fistula	6%
165	Cutaneous Fistula	6%
166	Cardiac Hypertrophy	6%
167	Genital Neoplasms, Female	5.9%
168	Uterine hemorrhage	5.9%
169	Rectocele	5.9%
170	Uterine Inversion	5.9%
171	Salpingitis	5.8%
172	Vulvovaginitis	5.8%
173	Fallopian Tube Neoplasms	5.7%
174	Penile Neoplasms	5.6%
175	Prostatic Neoplasms	5.6%
176	Dyspareunia	5.5%
177	Fetal Death	5.3%
178	Perinatal death	5.3%
179	Menorrhagia	5.1%
180	Nasal Polyps	5.1%
181	Epididymitis	5%
182	Penile Diseases	5%
183	Prostatic Diseases	5%
184	Spermatic Cord Torsion	5%
185	Hemospermia	5%
186	Testicular Hydrocele	5%
187	Uterine Rupture	5%
188	Meningocele	4.9%
189	Encephalocele	4.9%
190	Colonic Polyps	4.9%
191	Endometrial Hyperplasia	4.9%
192	Pyometra	4.9%
193	Vaginitis	4.9%
194	Vulvitis	4.9%
195	Vaginal Discharge	4.9%
196	Vulvodynia	4.9%
197	Oophoritis	4.9%
198	Endometrial Neoplasms	4.8%
199	Cryptorchidism	4.8%
200	Gonadal Dysgenesis	4.7%
201	Adrenogenital Syndrome	4.7%
202	Ovotesticular Disorders of Sex Development	4.7%
203	Morning Sickness	4.6%
204	Hyperandrogenism	4.4%
205	Postpartum Hemorrhage	4.4%
206	ovarian neoplasm	4.3%
207	Carcinoma, Endometrioid	4.3%
208	Leukoplakia, Oral	4.2%
209	Uterine Cervical Incompetence	4.2%
210	Metrorrhagia	4.2%
211	Ascites	4.2%
212	Asthenia	4.2%
213	Body Temperature Changes	4.2%
214	Cyanosis	4.2%
215	Edema	4.2%
216	Failure to Thrive	4.2%
217	Fatigue	4.2%
218	Feminization	4.2%
219	Fetal Distress	4.2%
220	Fibrosis	4.2%
221	Gliosis	4.2%
222	Growth Disorders	4.2%
223	Hemorrhage	4.2%
224	Polyhydramnios	4.2%
225	Hyperbilirubinemia	4.2%
226	Hyperplasia	4.2%
227	Hypomenorrhea	4.2%
228	Inflammation	4.2%
229	Intraoperative Complications	4.2%
230	Ischemia	4.2%
231	Obstetric Labor Complications	4.2%
232	Lithiasis	4.2%
233	Malacoplakia	4.2%
234	Menstruation Disturbances	4.2%
235	Metaplasia	4.2%
236	Motion Sickness	4.2%
237	Nerve Degeneration	4.2%
238	Ochronosis	4.2%
239	Polymenorrhea	4.2%
240	Postoperative Complications	4.2%
241	Ectopic Pregnancy	4.2%
242	Pregnancy, Prolonged	4.2%
243	Puerperal Disorders	4.2%
244	Sclerosis	4.2%
245	Shock	4.2%
246	Signs and Symptoms, Digestive	4.2%
247	Signs and Symptoms, Respiratory	4.2%
248	Skin Manifestations	4.2%
249	Ulcer	4.2%
250	Oligohydramnios	4.2%
251	Chills	4.2%
252	Prenatal Injuries	4.2%
253	Lassitude	4.2%
254	Hyperammonemia	4.2%
255	Hyperamylasemia	4.2%
256	Teratogenesis	4.2%
257	Cardiac Death	4.2%
258	Hypovolemia	4.2%
259	Pseudophakia	4.2%
260	Hyperuricemia	4.2%
261	Urological Manifestations	4.2%
262	Leukoaraiosis	4.2%
263	Dysbacteriosis	4.2%
264	Mobility Limitation	4.2%
265	Delayed Graft Function	4.2%
266	Cirrhosis	4.2%
267	Somnolence	4.2%
268	Neointima	4.2%
269	Dysbiosis	4.2%
270	Prostatic Neoplasms, Castration-Resistant	4.2%
271	Testicular Diseases	4.1%
272	Varicocele	4.1%
273	Candidiasis, Vulvovaginal	4%
274	Sarcopenia	4%
275	Biliary Fistula	4%
276	Gastric Fistula	4%
277	Ovarian Diseases	4%
278	Congenital diaphragmatic hernia	4%
279	Abruptio Placentae	3.9%
280	Infarction	3.9%
281	Placenta Accreta	3.9%
282	Postoperative Hemorrhage	3.9%
283	Shock, Hemorrhagic	3.9%
284	Systemic Inflammatory Response Syndrome	3.9%
285	Embryo Loss	3.9%
286	jaundice	3.9%
287	Adnexitis	3.9%
288	Dental Fistula	3.9%
289	Oroantral Fistula	3.9%
290	Pruritus Vulvae	3.9%
291	Left Ventricular Hypertrophy	3.9%
292	Right Ventricular Hypertrophy	3.9%
293	Pelvic Inflammatory Disease	3.9%
294	Postoperative Nausea and Vomiting	3.8%
295	Chorioamnionitis	3.8%
296	Uterine Cervicitis	3.6%
297	Leukorrhea	3.6%
298	Parametritis	3.6%
299	Extravasation of Diagnostic and Therapeutic Materials	3.5%
300	Eye Manifestations	3.5%
301	Fetal Diseases	3.5%
302	Neoplastic Processes	3.5%
303	Neurologic Manifestations	3.5%
304	Pregnancy Complications, Cardiovascular	3.5%
305	Pregnancy Complications, Neoplastic	3.5%
306	Familial Hypophosphatemic Rickets	3.5%
307	Eye Hemorrhage	3.4%
308	Necrosis	3.4%
309	Pregnancy Complications, Hematologic	3.4%
310	Pregnancy Complications, Infectious	3.4%
311	Cardiac Output, High	3.4%
312	Myocardial Stunning	3.4%
313	Reticulocytosis	3.4%
314	Granulomatosis, Orofacial	3.4%
315	Pigmentation Disorders	3.4%
316	Low Cardiac Output Syndrome	3.4%
317	Respiratory Aspiration	3.4%
318	Bronchial Fistula	3.4%
319	Pancreatic Fistula	3.4%
320	Muscle Weakness	3.3%
321	Acantholysis	3.3%
322	Chromosome Aberrations	3.3%
323	Dehydration	3.3%
324	Fetal Growth Retardation	3.3%
325	Granuloma	3.3%
326	Hemoptysis	3.3%
327	Leukocytosis	3.3%
328	Pleocytosis	3.3%
329	Intestinal Fistula	3.3%
330	Gastroschisis	3.3%
331	Enterocutaneous Fistula	3.3%
332	Intermittent Claudication	3.3%
333	Ecchymosis	3.3%
334	Petechiae	3.3%
335	Puerperal Infection	3.3%
336	Purpura	3.3%
337	Renal Colic	3.3%
338	Balanitis	3.3%
339	Benign prostatic hypertrophy	3.3%
340	Phimosis	3.3%
341	Priapism	3.3%
342	prostatitis	3.3%
343	Salivary Gland Fistula	3.3%
344	Prostatic Adenoma	3.3%
345	Benign Prostatic Hyperplasia	3.3%
346	Prostatic Hypertrophy	3.3%
347	Prostatic Hyperplasia	3.3%
348	Abdominal Pain	3.3%
349	Fetal Resorption	3.3%
350	Pain, Postoperative	3.3%
351	Endometrial Stromal Sarcoma	3.1%
352	Chlamydia Infections	3%
353	Gonorrhea	3%
354	Turner Syndrome	3%
355	Umbilical hernia	3%
356	Bacterial Vaginosis	3%
357	granulosa cell tumor	3%
358	Carcinoma, Ovarian Epithelial	3%
359	Testicular Neoplasms	3%
360	Dysmenorrhea	2.9%
361	Hyperemesis Gravidarum	2.9%
362	Trichomonas Vaginitis	2.9%
363	Uterine Perforation	2.9%
364	Ovarian Hyperstimulation Syndrome	2.9%
365	Failed Back Surgery Syndrome	2.9%
366	Epistaxis	2.9%
367	Genomic Instability	2.9%
368	Chromosomal Instability	2.8%
369	Hypergammaglobulinemia	2.8%
370	Gestational Diabetes	2.8%
371	Eye pain	2.8%
372	Fetal Hypoxia	2.8%
373	Kallmann Syndrome	2.7%
374	Stillbirth	2.7%
375	Syphilis	2.7%
376	Premature Ejaculation	2.7%
377	Erectile dysfunction	2.7%
378	Orchitis	2.6%
379	Jaundice, Obstructive	2.6%
380	Sudden infant death syndrome	2.6%
381	Lymphogranuloma Venereum	2.5%
382	Corpus Luteum Cyst	2.5%
383	Ovarian Cysts	2.5%
384	Abortion, Habitual	2.5%
385	Acute Disease	2.5%
386	Acute-Phase Reaction	2.5%
387	Amenorrhea	2.5%
388	Anorexia	2.5%
389	Anoxia	2.5%
390	Chronic disease	2.5%
391	Constipation	2.5%
392	Critical Illness	2.5%
393	Sudden death	2.5%
394	Diarrhea	2.5%
395	Dyspepsia	2.5%
396	Dystocia	2.5%
397	Eclampsia	2.5%
398	Eructation	2.5%
399	Fat necrosis	2.5%
400	Fetal Membranes, Premature Rupture	2.5%
401	Fever	2.5%
402	Flatulence	2.5%
403	Flushing	2.5%
404	Gangrene	2.5%
405	Graft Occlusion, Vascular	2.5%
406	Granuloma, Plasma Cell	2.5%
407	Halitosis	2.5%
408	Heartburn	2.5%
409	Hematoma	2.5%
410	Hiccough	2.5%
411	Hypercalciuria	2.5%
412	Hypercapnia	2.5%
413	Hyperphagia	2.5%
414	Iatrogenic Disease	2.5%
415	Multiple Organ Failure	2.5%
416	Nausea	2.5%
417	Oligomenorrhea	2.5%
418	Pallor	2.5%
419	Placental Insufficiency	2.5%
420	Pre-Eclampsia	2.5%
421	Premenstrual syndrome	2.5%
422	Prenatal Exposure Delayed Effects	2.5%
423	Psychophysiologic Disorders	2.5%
424	Recurrence	2.5%
425	Retrograde Degeneration	2.5%
426	Retroperitoneal fibrosis	2.5%
427	Serositis	2.5%
428	Subcutaneous Emphysema	2.5%
429	Surgical Wound Dehiscence	2.5%
430	Syndrome	2.5%
431	Vomiting	2.5%
432	Wallerian Degeneration	2.5%
433	Hypocapnia	2.5%
434	Pyogenic granuloma	2.5%
435	HELLP Syndrome	2.5%
436	Exsanguination	2.5%
437	Dyschezia	2.5%
438	Hypoxia	2.5%
439	Disease Progression	2.5%
440	Placenta, Retained	2.5%
441	Hyperoxia	2.5%
442	Seroma	2.5%
443	Premenstrual Tension	2.5%
444	Delayed Emergence from Anesthesia	2.5%
445	Infant Death	2.5%
446	Lower Urinary Tract Symptoms	2.5%
447	Hypoxemia	2.5%
448	Anastomotic Leak	2.5%
449	Intraoperative Awareness	2.5%
450	Urinoma	2.5%
451	Anovulation	2.4%
452	Azoospermia	2.4%
453	Oligospermia	2.4%
454	Impotence, Vasculogenic	2.4%
455	Asthenozoospermia	2.4%
456	Teratozoospermia	2.4%
457	Aspermia	2.4%
458	Klinefelter Syndrome	2.4%
459	Premature Menopause	2.4%
460	Cardiotoxicity	2.4%
461	Abdomen, Acute	2.3%
462	Hematemesis	2.2%
463	Arteriovenous fistula	2.2%
464	Purpura Fulminans	2.2%
465	Rectal Fistula	2.1%
466	Anal Fistula	2.1%
467	Abortion, Veterinary	2.1%
468	Asphyxia	2.1%
469	Granuloma, Respiratory Tract	2.1%
470	Shock, Traumatic	2.1%
471	Pregnancy Complications, Parasitic	2.1%
472	Body Weight	2%
473	Polycystic Ovary Syndrome	2%
474	Phantom pain	2%
475	Phantom Limb Pain	2%
476	Apnea	2%
477	Cheyne-Stokes Respiration	2%
478	Decerebrate State	2%
479	Disease susceptibility	2%
480	Dyspnea	2%
481	Foreign-Body Reaction	2%
482	Gastrointestinal Hemorrhage	2%
483	Hemarthrosis	2%
484	Hemiparesis	2%
485	Hemoperitoneum	2%
486	Hemothorax	2%
487	Hyperventilation	2%
488	Meningism	2%
489	Mouth Breathing	2%
490	Neoplasm Invasiveness	2%
491	Neoplasm Metastasis	2%
492	Neoplasm Recurrence, Local	2%
493	Paresis	2%
494	Postpericardiotomy Syndrome	2%
495	Prosthesis Failure	2%
496	Pruritus	2%
497	Reperfusion Injury	2%
498	Seizures	2%
499	Sensation Disorders	2%
500	Sneezing	2%
501	Erythema	2%
502	Complex partial seizures	2%
503	Injection Site Reaction	2%
504	Necrolytic Migratory Erythema	2%
505	Tachypnea	2%
506	Monoparesis	2%
507	Retrobulbar Hemorrhage	2%
508	Aseptic Necrosis of Bone	2%
509	Peritoneal Fibrosis	2%
510	Carcinogenesis	2%
511	Neurogenic Inflammation	2%
512	Gait Disorders, Neurologic	2%
513	Neuromuscular Manifestations	2%
514	Infusion site reaction	2%
515	Nephrogenic Fibrosing Dermopathy	2%
516	Corneal Endothelial Cell Loss	2%
517	Encapsulating Peritoneal Sclerosis	2%
518	Vasoplegia	2%
519	Suppuration	2%
520	Nephrogenic Systemic Fibrosis	2%
521	Metastasis	2%
522	Sinus Arrhythmia	2%
523	Atrial Fibrillation	2%
524	Atrial Flutter	2%
525	Dental Pulp Necrosis	2%
526	Edema, Cardiac	2%
527	Mental Fatigue	2%
528	Granuloma, Foreign-Body	2%
529	Hirsutism	2%
530	Lactation Disorder	2%
531	Mastitis	2%
532	Mediastinal Emphysema	2%
533	Surgical Wound Infection	2%
534	Ventricular Fibrillation	2%
535	Ventricular Flutter	2%
536	Parasystole	2%
537	Depression, Postpartum	2%
538	Paroxysmal atrial fibrillation	2%
539	Facies	2%
540	Bradycardia	2%
541	Orthostatic intolerance	2%
542	Hypoventilation	2%
543	Afferent Loop Syndrome	2%
544	Sex Chromosome Aberrations	2%
545	Short Bowel Syndrome	2%
546	No-Reflow Phenomenon	2%
547	Body Weight Changes	2%
548	Endotoxic shock	1.9%
549	Septic Shock	1.9%
550	Toxic Shock Syndrome	1.9%
551	Chromosome Fragility	1.9%
552	Hoarseness	1.8%
553	Sleep Wake Disorders	1.8%
554	Pupil Disorders	1.7%
555	Neurobehavioral Manifestations	1.7%
556	Drowning	1.7%
557	Pleural Rub	1.7%
558	Rales	1.7%
559	Respiratory Sounds	1.7%
560	Rhonchi	1.7%
561	Stridor	1.7%
562	Trophoblastic Neoplasms	1.7%
563	Wheezing	1.7%
564	Asterixis	1.7%
565	Ballismus	1.7%
566	DNA Degradation, Necrotic	1.7%
567	Thrombocytopenic purpura	1.7%
568	Aneuploidy	1.7%
569	Embolism, Amniotic Fluid	1.7%
570	Polyploidy	1.7%
571	Vertigo	1.7%
572	Microsatellite Instability	1.7%
573	Fetal Alcohol Spectrum Disorders	1.7%
574	Heart Block	1.6%
575	Pain	1.6%
576	Tachycardia	1.6%
577	Tachyarrhythmia	1.6%
578	Livedo Reticularis	1.6%
579	Ache	1.6%
580	Cicatrix	1.6%
581	Hydrops Fetalis	1.6%
582	Granuloma Annulare	1.6%
583	Chromosome Breakage	1.6%
584	Brain Death	1.6%
585	Breech Presentation	1.6%
586	Shock, Cardiogenic	1.6%
587	Tissue Adhesions	1.6%
588	Back Pain	1.6%
589	Bulimia	1.6%
590	Neck Pain	1.6%
591	Chest Pain	1.6%
592	Dizziness	1.6%
593	Dysuria	1.6%
594	Facial Pain	1.6%
595	Fever of Unknown Origin	1.6%
596	Flank Pain	1.6%
597	Headache	1.6%
598	Nocturia	1.6%
599	Pain, Intractable	1.6%
600	Pelvic Pain	1.6%
601	Purpura, Hyperglobulinemic	1.6%
602	Snoring	1.6%
603	Chronic pain	1.6%
604	Premature Birth	1.6%
605	Lightheadedness	1.6%
606	Pain, Referred	1.6%
607	Prostatism	1.6%
608	Throbbing Headache	1.6%
609	Labor Pain	1.6%
610	Cancer Pain	1.6%
611	Hematoma, Epidural, Spinal	1.6%
612	Nociceptive Pain	1.6%
613	Gait Ataxia	1.6%
614	Sick Sinus Syndrome	1.6%
615	Trisomy	1.6%
616	Underweight	1.6%
617	Overweight	1.6%
618	Leydig Cell Tumor	1.6%
619	Voice Disorders	1.5%
620	Voice Disturbance	1.5%
621	Giant Cell Epulis	1.4%
622	Hematoma, Subdural	1.4%
623	Hematoma, Epidural, Cranial	1.4%
624	Gagging	1.4%
625	Akathisia	1.4%
626	Restlessness	1.4%
627	Psychomotor Agitation	1.4%
628	Long QT Syndrome	1.4%
629	Micronuclei, Chromosome-Defective	1.4%
630	Cross Infection	1.3%
631	Hyphema	1.3%
632	Retinal Neovascularization	1.3%
633	Septicemia	1.3%
634	Vitreous Hemorrhage	1.3%
635	Sepsis	1.3%
636	Gait Apraxia	1.3%
637	Abscess	1.3%
638	Anosmia	1.3%
639	Ataxia	1.3%
640	Athetosis	1.3%
641	Catalepsy	1.3%
642	Dystonia	1.3%
643	Empyema	1.3%
644	Femur Head Necrosis	1.3%
645	Hemiplegia	1.3%
646	Locked-In Syndrome	1.3%
647	Lymphatic Metastasis	1.3%
648	Muscle Hypertonia	1.3%
649	Muscle hypotonia	1.3%
650	Myoclonus	1.3%
651	Myotonia	1.3%
652	Neoplasms, Unknown Primary	1.3%
653	Neuralgia	1.3%
654	Paraplegia	1.3%
655	Peptic Ulcer Hemorrhage	1.3%
656	Pseudobulbar Palsy	1.3%
657	Quadriplegia	1.3%
658	Spasm	1.3%
659	Spastic Paraplegia	1.3%
660	Status Epilepticus	1.3%
661	Taste Disorders	1.3%
662	Tremor	1.3%
663	Sudden Cardiac Death	1.3%
664	Monoplegia	1.3%
665	Hypokinesia	1.3%
666	Gastroparesis	1.3%
667	Leukemic Infiltration	1.3%
668	Paraparesis	1.3%
669	Bradykinesia	1.3%
670	Waxy flexibility	1.3%
671	Action Tremor	1.3%
672	Resting Tremor	1.3%
673	Dysosmia	1.3%
674	Quadriparesis	1.3%
675	Premenstrual Dysphoric Disorder	1.3%
676	Olfaction Disorders	1.3%
677	Choroidal Neovascularization	1.3%
678	Myokymia	1.3%
679	Somatosensory Disorders	1.3%
680	Primary Graft Dysfunction	1.3%
681	Neoplasm Micrometastasis	1.3%
682	Neuropathic pain	1.3%
683	Hyperkinesia	1.3%
684	Intention tremor	1.3%
685	Dumping Syndrome	1.3%
686	Cicatrix, Hypertrophic	1.3%
687	Sinus Arrest, Cardiac	1.3%
688	Galactorrhea	1.3%
689	Weight Gain	1.3%
690	Meconium Aspiration Syndrome	1.3%
691	Subacute Combined Degeneration	1.3%
692	Jet Lag Syndrome	1.2%
693	Eosinophilic Granuloma	1.2%
694	Reflex, Abnormal	1.2%
695	Hyporeflexia	1.2%
696	Hyperreflexia	1.2%
697	Emaciation	1.2%
698	Low Back Pain	1.2%
699	Visceral Pain	1.2%
700	Hematoma, Subdural, Spinal	1.2%
701	Purpura, Thrombotic Thrombocytopenic	1.2%
702	Birth Weight	1.2%
703	Vision Disorders	1.1%
704	Metamorphopsia	1.1%
705	Visual Impairment	1.1%
706	Metatarsalgia	1.1%
707	Retinal Hemorrhage	1.1%
708	Kernicterus	1.1%
709	Anisocoria	1.1%
710	Choroid Hemorrhage	1.1%
711	Confusion	1.1%
712	Facial paralysis	1.1%
713	Lethargy	1.1%
714	Melena	1.1%
715	Memory Disorders	1.1%
716	Muscle Cramp	1.1%
717	Perceptual Disorders	1.1%
718	Psychomotor Disorders	1.1%
719	Tonic Pupil	1.1%
720	Anhedonia	1.1%
721	Disorientation	1.1%
722	Facial Paresis	1.1%
723	Memory Loss	1.1%
724	Hemisensory Neglect	1.1%
725	Dysacusis	1.1%
726	Dyspnea, Paroxysmal	1.1%
727	Mastodynia	1.1%
728	Respiratory Paralysis	1.1%
729	Chorea	1.1%
730	Gingival Hemorrhage	1.1%
731	Keloid	1.1%
732	Tetany	1.1%
733	Breakthrough Pain	1.1%
734	Monosomy	1.1%
735	Tetraploidy	1.1%
736	Adams-Stokes Syndrome	1.1%
737	Atrioventricular Block	1.1%
738	Bundle-Branch Block	1.1%
739	Atrial Premature Complexes	1.1%
740	Sinoatrial Block	1.1%
741	Tachycardia, Paroxysmal	1.1%
742	Supraventricular tachycardia	1.1%
743	Tachycardia, Ventricular	1.1%
744	Tachycardia, Reciprocating	1.1%
745	Subarachnoid Hemorrhage	1.1%
746	Cerebral Hemorrhage	1.1%
747	Waterhouse-Friderichsen Syndrome	1.1%
748	Alice in Wonderland Syndrome	1.1%
749	Hematoma, Subdural, Intracranial	1.1%
750	Hematoma, Subdural, Chronic	1.1%
751	Hematoma, Subdural, Acute	1.1%
752	Viremia	1%
753	Parasitemia	1%
754	Cachexia	1%
755	Alexia	1%
756	Dyslexia	1%
757	Toothache	1%
758	Autoimmune thrombocytopenia	1%
759	Immune thrombocytopenic purpura	1%
760	Fetal Weight	1%
761	Dysgeusia	1%
762	Formication	1%
763	Hyperalgesia	1%
764	Hyperesthesia	1%
765	Hypesthesia	1%
766	Language Disorders	1%
767	Numbness	1%
768	Paresthesia	1%
769	Paraparesis, Spastic	1%
770	Trismus	1%
771	Epilepsia Partialis Continua	1%
772	Hypogeusia	1%
773	Brown-Sequard Syndrome	1%
774	Lockjaw	1%
775	Allodynia	1%
776	Ageusia	1%
777	Consciousness Disorders	1%
778	Mental Retardation	1%
779	Depressed Level of Consciousness	1%
780	Mental deficiency	1%
781	Intellectual Disability	1%
782	Catatonia	0.9%
783	Cellulitis	0.9%
784	Musculoskeletal Pain	0.9%
785	Ophthalmoplegia	0.9%
786	External Ophthalmoplegia	0.9%
787	Aphonia	0.9%
788	Arthralgia	0.9%
789	Sleep Deprivation	0.9%
790	Polyarthralgia	0.9%
791	Dysphonia	0.9%
792	Cerebrospinal Fluid Otorrhea	0.9%
793	Cerebrospinal Fluid Rhinorrhea	0.9%
794	Choriocarcinoma	0.9%
795	Romano-Ward Syndrome	0.9%
796	Obesity	0.9%
797	Granuloma, Laryngeal	0.8%
798	Vocal Cord Paralysis	0.8%
799	Bacteremia	0.8%
800	Myocardial Reperfusion Injury	0.8%
801	Cell Transformation, Viral	0.8%
802	Diplopia	0.8%
803	Muscle Rigidity	0.8%
804	Muscle Spasticity	0.8%
805	Scotoma	0.8%
806	Photophobia	0.8%
807	Cogwheel Rigidity	0.8%
808	Hemifacial Spasm	0.8%
809	Amaurosis	0.8%
810	Blindness	0.8%
811	Nuchal Rigidity	0.8%
812	Angina Pectoris	0.8%
813	Fungemia	0.8%
814	Agnosia	0.8%
815	Apraxias	0.8%
816	Hallucinations	0.8%
817	Hemianopsia	0.8%
818	Hyperacusis	0.8%
819	Tinnitus	0.8%
820	Visual Agnosia	0.8%
821	Anosognosia	0.8%
822	Wernicke-Korsakoff Syndrome	0.8%
823	Phonophobia	0.8%
824	Hearing Loss	0.8%
825	Cerebellar Ataxia	0.8%
826	Torticollis	0.8%
827	Hydatidiform Mole	0.8%
828	Sciatica	0.8%
829	Tinea Pedis	0.8%
830	Tardive Dyskinesia	0.8%
831	Agraphia	0.8%
832	Anomia	0.8%
833	Cluttering	0.8%
834	Language Development Disorders	0.8%
835	Speech Disorders	0.8%
836	Syncope	0.8%
837	Stupor	0.8%
838	Dysgraphia	0.8%
839	Presyncope	0.8%
840	Dyslalia	0.8%
841	Tachycardia, Atrioventricular Nodal Reentry	0.8%
842	Tachycardia, Ectopic Atrial	0.8%
843	Tachycardia, Ectopic Junctional	0.8%
844	Sinus Tachycardia	0.8%
845	Torsades de Pointes	0.8%
846	Accelerated Idioventricular Rhythm	0.8%
847	Dyskinesia, Drug-Induced	0.7%
848	Alcohol Withdrawal Seizures	0.7%
849	Aphasia	0.7%
850	Articulation Disorders	0.7%
851	Echolalia	0.7%
852	Stuttering	0.7%
853	Dysphasia	0.7%
854	Philadelphia Chromosome	0.7%
855	Amblyopia	0.7%
856	Amnesia	0.7%
857	Delirium	0.7%
858	Horner Syndrome	0.7%
859	Dissociative Amnesia	0.7%
860	Color blindness	0.7%
861	Global Amnesia	0.7%
862	Shoulder Pain	0.7%
863	Pediatric Obesity	0.7%
864	Dysarthria	0.7%
865	Endotoxemia	0.7%
866	Amaurosis Fugax	0.7%
867	Blindness, Cortical	0.7%
868	Dyscalculia	0.7%
869	Angina, Unstable	0.7%
870	Deafness	0.7%
871	Hearing Loss, Sudden	0.7%
872	Gerstmann Syndrome	0.7%
873	Hearing Loss, Bilateral	0.7%
874	Hearing Loss, High-Frequency	0.7%
875	Hearing Loss, Mixed Conductive-Sensorineural	0.7%
876	Prosopagnosia	0.7%
877	Apraxia, Ideomotor	0.7%
878	Persistent Vegetative State	0.7%
879	Charles Bonnet Syndrome	0.7%
880	Hearing Loss, Unilateral	0.7%
881	Complete Hearing Loss	0.7%
882	Alien Hand Syndrome	0.7%
883	Deaf Mutism	0.7%
884	Akathisia, Drug-Induced	0.6%
885	Myalgia	0.6%
886	Mutism	0.6%
887	Selective Mutism	0.6%
888	Angina Pectoris, Variant	0.6%
889	Retrograde amnesia	0.6%
890	Amnesia, Anterograde	0.6%
891	Alexia, Pure	0.6%
892	Auditory Perceptual Disorders	0.5%
893	Basal Ganglia Hemorrhage	0.5%
894	Amnesia, Transient Global	0.5%
895	Candidemia	0.5%
896	Ophthalmoplegic Migraine	0.5%
897	Progressive supranuclear palsy	0.5%
898	Putaminal Hemorrhage	0.4%
899	Kearns-Sayre syndrome	0.3%

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