MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Breech Presentation

(UMLS:C0006157)

Definition:: A malpresentation of the FETUS at near term or during OBSTETRIC LABOR with the fetal cephalic pole in the fundus of the UTERUS. There are three types of breech: the complete breech with flexed hips and knees; the incomplete breech with one or both hips partially or fully extended; the frank breech with flexed hips and extended knees.
UMLS ID:: C0006157
MeSH ID:: D001946

Classification 1:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.703.420.183

Classification 2:

Name:

Reproductive and Urinary Physiological Phenomena
MeSH Tree Number(s):: G08.686.520.150|G08.686.784.769.326.520.150

Synonym(s)

Breech Presentation

Breech presentation

Breech presentation at birth

FETAL PRESENTATION BREECH

Feet or buttocks of fetus positioned near opening of uterus

Malposition of fetus in breech presentation

Positions of breech presentation

a buttocks presentation was observed

breech presentation

10.

breech presentation of fetus

11.

breech presentations

12.

breech; presentation

13.

buttocks presentation

14.

presentation; breech

Associated Drug(s)

	Name	Number of Reports	Data Source
1	17 alpha-Hydroxyprogesterone Caproate	FAERS: 39	US FAERS
2	Norgestrel	FAERS: 14	US FAERS
3	Aripiprazole	FAERS: 11	OFFSIDES US FAERS
4	Fluoxetine	FAERS: 11	US FAERS
5	Isotretinoin	FAERS: 11	US FAERS
6	Dimethyl Fumarate	FAERS: 10	US FAERS
7	Levetiracetam	FAERS: 8	US FAERS
8	Fingolimod Hydrochloride	FAERS: 7	US FAERS
9	NuvaRing	FAERS: 6	OFFSIDES US FAERS
10	Sertraline	FAERS: 6	US FAERS
11	Imatinib Mesylate	FAERS: 5	US FAERS
12	Carbamazepine	FAERS: 4	US FAERS
13	Methyldopa	FAERS: 4	OFFSIDES US FAERS
14	Thyroxine	FAERS: 4	US FAERS
15	Valsartan	FAERS: 4	US FAERS
16	Clomiphene	FAERS: 3	US FAERS
17	Letrozole	FAERS: 3	OFFSIDES US FAERS
18	Lopinavir	FAERS: 3 Canada Vigilance: 1	Canada Vigilance US FAERS
19	Prednisolone	FAERS: 3	US FAERS
20	Venlafaxine Hydrochloride	FAERS: 3	US FAERS
21	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride	FAERS: 2	US FAERS
22	Citalopram	FAERS: 2	US FAERS
23	Cyclosporine	FAERS: 2	US FAERS
24	Lamotrigine	FAERS: 2	US FAERS
25	Lisinopril	FAERS: 2	US FAERS
26	Metformin	FAERS: 2	US FAERS
27	Modafinil	FAERS: 2	US FAERS
28	Qlaira	FAERS: 2	US FAERS
29	Tacrolimus	FAERS: 2	US FAERS
30	Thyroxine	FAERS: 2	US FAERS
31	Valproic Acid	FAERS: 2	US FAERS
32	4-hydroxybutyric acid	FAERS: 1	US FAERS
33	Acitretin	FAERS: 1	US FAERS
34	Albuterol	FAERS: 1	US FAERS
35	Butorphanol	FAERS: 1	US FAERS
36	Cefdinir	FAERS: 1	US FAERS
37	Citalopram	FAERS: 1	US FAERS
38	Colestipol	FAERS: 1	US FAERS
39	Deferiprone	FAERS: 1	US FAERS
40	Finasteride	FAERS: 1	US FAERS
41	Fluoxetine	FAERS: 1	US FAERS
42	Glatiramer Acetate	FAERS: 1	US FAERS
43	Imatinib Mesylate	FAERS: 1	US FAERS
44	Imiquimod	FAERS: 1	US FAERS
45	Ketamine	FAERS: 1	OFFSIDES US FAERS
46	Lansoprazole	FAERS: 1	US FAERS
47	Lurasidone Hydrochloride	FAERS: 1	US FAERS
48	Medroxyprogesterone Acetate	FAERS: 1	US FAERS
49	Mesalamine	FAERS: 1	US FAERS
50	Metronidazole	FAERS: 1	US FAERS
51	Nicotine	FAERS: 1	US FAERS
52	Nortriptyline	FAERS: 1	US FAERS
53	Omeprazole	FAERS: 1	US FAERS
54	Ondansetron	FAERS: 1	US FAERS
55	Oxcarbazepine	FAERS: 1	US FAERS
56	Succinylcholine	FAERS: 1	US FAERS
57	Sumatriptan	FAERS: 1	US FAERS
58	Ursodeoxycholic Acid	FAERS: 1	US FAERS
59	Valacyclovir	FAERS: 1	US FAERS
60	Valproic Acid	FAERS: 1	US FAERS
61	Venlafaxine Hydrochloride	FAERS: 1	US FAERS
62	Warfarin	FAERS: 1	US FAERS
63	etonogestrel	FAERS: 1	US FAERS
64	reviparin	FAERS: 1	US FAERS
65	rotigotine	FAERS: 1	US FAERS
66	ulipristal acetate	FAERS: 1	US FAERS
67	Ampicillin		OFFSIDES
68	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination		OFFSIDES
69	Azathioprine		OFFSIDES
70	Bromocriptine		OFFSIDES
71	Bupropion		OFFSIDES
72	Calcium Citrate		OFFSIDES
73	Cefadroxil		OFFSIDES
74	Clozapine		OFFSIDES
75	Erythromycin		OFFSIDES
76	Fentanyl		OFFSIDES
77	Imipramine		OFFSIDES
78	Leflunomide		OFFSIDES
79	Meperidine		OFFSIDES
80	Methylphenidate		OFFSIDES
81	Misoprostol		OFFSIDES
82	Nevirapine		OFFSIDES
83	Nitrofurantoin		OFFSIDES
84	Piperacillin, Tazobactam Drug Combination		OFFSIDES
85	Potassium Iodide		OFFSIDES
86	Prazepam		OFFSIDES
87	Propylthiouracil		OFFSIDES
88	Salmeterol Xinafoate		OFFSIDES
89	Tenofovir		OFFSIDES
90	Tretinoin		OFFSIDES
91	abacavir, lamivudine drug combination		OFFSIDES
92	efavirenz		OFFSIDES
93	ferrous gluconate		OFFSIDES
94	norgestimate, ethinyl estradiol drug combination		OFFSIDES
95	rizatriptan		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Multiple Pregnancy	38.8%
2	Puberty	33.1%
3	Abruptio Placentae	26.4%
4	Placenta Accreta	26.4%
5	Dystocia	23%
6	Fetal Membranes, Premature Rupture	23%
7	Fertilization	22.8%
8	Unwanted pregnancy	22.6%
9	Postpartum Hemorrhage	21.9%
10	Chorioamnionitis	21.4%
11	Menarche	20.6%
12	Menopause	20.6%
13	Andropause	20.6%
14	Uterine Inversion	20.3%
15	Uterine Rupture	17.2%
16	Premature Birth	17.1%
17	Stillbirth	16.7%
18	Live Birth	15.2%
19	Polyhydramnios	15%
20	Ectopic Pregnancy	15%
21	Pregnancy, Prolonged	15%
22	Puerperal Disorders	15%
23	Oligohydramnios	15%
24	Prenatal Injuries	15%
25	Postmenopause	14.6%
26	Premature Menopause	13.5%
27	Puerperal Infection	13.2%
28	Fetal Diseases	12.5%
29	Pregnancy Complications, Cardiovascular	12.5%
30	Pregnancy Complications, Neoplastic	12.5%
31	Bisexuality	12.3%
32	Homosexuality	12.3%
33	Pregnancy Complications, Hematologic	12.2%
34	Pregnancy Complications, Infectious	12.2%
35	Fetal Death	12%
36	Perinatal death	12%
37	Morning Sickness	11.9%
38	Anovulation	11%
39	Gestational Diabetes	10.1%
40	Fetal Weight	10%
41	Abortion, Habitual	9.9%
42	Eclampsia	9.9%
43	Placental Insufficiency	9.9%
44	Pre-Eclampsia	9.9%
45	Pregnancy	9.9%
46	Prenatal Exposure Delayed Effects	9.9%
47	HELLP Syndrome	9.9%
48	Placenta, Retained	9.9%
49	Superovulation	9.6%
50	Female Urogenital Diseases	8.6%
51	Diuresis	8.6%
52	Abortion, Veterinary	8.2%
53	Pregnancy Complications, Parasitic	8.2%
54	Lactation Disorder	7.9%
55	Mastitis	7.9%
56	Depression, Postpartum	7.9%
57	Embryo Loss	7.9%
58	Fetal Resorption	7.9%
59	Hyperemesis Gravidarum	7.8%
60	Uterine Cervical Incompetence	7.5%
61	Breech Presentation	7.4%
62	Glomerular Filtration Rate	6.8%
63	Fetal Growth Retardation	6.7%
64	Trophoblastic Neoplasms	6.7%
65	Embolism, Amniotic Fluid	6.6%
66	Fetal Hypoxia	6.6%
67	Fetal Alcohol Spectrum Disorders	6.6%
68	Galactorrhea	5.9%
69	Meconium Aspiration Syndrome	5.1%
70	Choriocarcinoma	4.2%
71	Urologic Diseases	4.2%
72	Hydatidiform Mole	4%
73	Endometritis	3.6%
74	Urogenital Abnormalities	3.5%
75	Endometriosis	3.3%
76	Uterine Diseases	3.3%
77	Vaginal Diseases	3.3%
78	Vulvar Diseases	3.3%
79	Endometrioma	3.3%
80	Uterine Neoplasms	3.2%
81	Vaginal Neoplasms	3.2%
82	Vulvar Neoplasms	3.2%
83	Uterine Cancer	3.2%
84	Salpingitis	3.2%
85	Vulvovaginitis	3.2%
86	Vesicovaginal Fistula	3%
87	Fallopian Tube Neoplasms	3%
88	Hydrops Fetalis	3%
89	Bladder Exstrophy	2.9%
90	Epispadias	2.9%
91	Tuberculosis, Renal	2.9%
92	Anuria	2.8%
93	Ureterolithiasis	2.8%
94	Nephrolithiasis	2.8%
95	Oophoritis	2.7%
96	Endometrial Neoplasms	2.7%
97	Multicystic Dysplastic Kidney	2.7%
98	Urinary Bladder Diseases	2.7%
99	Infertility	2.7%
100	Kidney Diseases	2.7%
101	Ureteral Diseases	2.7%
102	Urethral Diseases	2.7%
103	Urination Disorders	2.7%
104	Urolithiasis	2.7%
105	Genital Neoplasms, Female	2.6%
106	Bladder neck obstruction	2.6%
107	Carcinoma, Endometrioid	2.5%
108	Urinary Bladder Fistula	2.5%
109	Bladder Neoplasm	2.5%
110	Kidney Neoplasm	2.5%
111	Ureteral Neoplasms	2.5%
112	Urethral Neoplasms	2.5%
113	Endometrial Hyperplasia	2.4%
114	Pyometra	2.4%
115	Vaginitis	2.4%
116	Vulvitis	2.4%
117	Vaginal Discharge	2.4%
118	Vulvodynia	2.4%
119	Candidiasis, Vulvovaginal	2.4%
120	Kidney Calculi	2.4%
121	Ureteral Calculi	2.4%
122	ovarian neoplasm	2.3%
123	Urinary tract infection	2.3%
124	Urologic Neoplasms	2.2%
125	Horseshoe Kidney	2.2%
126	Pyelocystitis	2.2%
127	Pyelonephritis	2.1%
128	Uterine Cervicitis	2%
129	Leukorrhea	2%
130	Parametritis	2%
131	Ovarian Diseases	2%
132	Sexually Transmitted Diseases	2%
133	Adnexitis	2%
134	Cystitis	2%
135	Hydronephrosis	2%
136	Hyperoxaluria	2%
137	Kidney Cortex Necrosis	2%
138	Kidney Papillary Necrosis	2%
139	Nephritis	2%
140	Nephrosclerosis	2%
141	Nephrosis	2%
142	Perinephritis	2%
143	Pruritus Vulvae	2%
144	Kidney Failure	2%
145	Uremia	2%
146	Ureteral obstruction	2%
147	Ureterocele	2%
148	Urethral Obstruction	2%
149	Urethritis	2%
150	Uterine hemorrhage	2%
151	Vaginal Fistula	2%
152	Vesico-Ureteral Reflux	2%
153	Urinary Retention	2%
154	Pelvic Inflammatory Disease	2%
155	Oxalosis	2%
156	Renal Insufficiency	2%
157	Endometrial Stromal Sarcoma	2%
158	Uterine Prolapse	2%
159	Vaginal Prolapse	2%
160	Hermaphroditism	1.9%
161	Disorders of Sex Development	1.9%
162	Hypospadias	1.9%
163	Genital Herpes	1.9%
164	Mesoblastic Nephroma	1.8%
165	Renal Cell Carcinoma	1.8%
166	Papillary Renal Cell Carcinoma	1.8%
167	granulosa cell tumor	1.7%
168	Carcinoma, Ovarian Epithelial	1.7%
169	Diabetes Insipidus	1.7%
170	Hepatorenal Syndrome	1.7%
171	Dyspareunia	1.7%
172	Bacterial Vaginosis	1.7%
173	Bacteriuria	1.6%
174	Diabetic Nephropathy	1.6%
175	Glycosuria	1.6%
176	Hematuria	1.6%
177	Renal hypertension	1.6%
178	Oliguria	1.6%
179	Polyuria	1.6%
180	Proteinuria	1.6%
181	Pyuria	1.6%
182	Renal Artery Obstruction	1.6%
183	Renal Artery Stenosis	1.6%
184	Urinary Calculi	1.6%
185	Cystocele	1.6%
186	Nephrocalcinosis	1.6%
187	Urinary Incontinence	1.6%
188	Trichomonas Vaginitis	1.6%
189	Uterine Perforation	1.6%
190	Ovarian Hyperstimulation Syndrome	1.6%
191	Glomerulonephritis	1.6%
192	Metrorrhagia	1.6%
193	Nephritis, Interstitial	1.6%
194	Lipoid nephrosis	1.6%
195	Nephrotic Syndrome	1.6%
196	Pyelitis	1.6%
197	Pyonephrosis	1.6%
198	Urethral Stenosis	1.6%
199	Nephrogenic Diabetes Insipidus	1.6%
200	Congenital Nephrogenic Diabetes Insipidus	1.6%
201	Acute kidney injury	1.6%
202	Urethral stricture	1.6%
203	Glycosuria, Renal	1.6%
204	Denys-Drash Syndrome	1.5%
205	Nephroblastoma	1.5%
206	Hyperandrogenism	1.5%
207	Balkan Nephropathy	1.5%
208	Focal glomerulosclerosis	1.5%
209	Kidney Failure, Chronic	1.5%
210	Enuresis	1.4%
211	Gonadal Dysgenesis	1.4%
212	Adrenogenital Syndrome	1.4%
213	Ovotesticular Disorders of Sex Development	1.4%
214	Corpus Luteum Cyst	1.4%
215	Ovarian Cysts	1.4%
216	Azotemia	1.4%
217	Menorrhagia	1.4%
218	Albuminuria	1.3%
219	Hemoglobinuria	1.3%
220	Hypertension, Renovascular	1.3%
221	Urge Incontinence	1.3%
222	Glomerulonephritis, Membranoproliferative	1.3%
223	AIDS-Associated Nephropathy	1.2%
224	Polycystic Ovary Syndrome	1.2%
225	Polycystic Kidney Diseases	1.2%
226	Diurnal Enuresis	1.2%
227	Renal Aminoacidurias	1.2%
228	Fanconi Syndrome	1.2%
229	Pseudohypoaldosteronism	1.2%
230	Liddle Syndrome	1.2%
231	Hemolytic-Uremic Syndrome	1.2%
232	Anti-Glomerular Basement Membrane Disease	1.1%
233	Lupus Nephritis	1%
234	Polycystic Kidney, Autosomal Dominant	1%
235	Cystinuria	1%
236	Atypical Hemolytic Uremic Syndrome	1%
237	Chlamydia Infections	1%
238	Gonorrhea	1%
239	Renal tubular acidosis	1%
240	Turner Syndrome	1%
241	Renal Osteodystrophy	1%
242	Renal rickets	1%
243	Kallmann Syndrome	0.9%
244	Lymphogranuloma Venereum	0.9%
245	Syphilis	0.9%
246	Hyperphosphaturia	0.8%
247	Klinefelter Syndrome	0.8%
248	Zellweger Syndrome	0.8%
249	Familial Hypophosphatemic Rickets	0.5%

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