MetaADEDB 2.0 @ LMMD
Fluvastatin
(FJLGEFLZQAZZCD-MCBHFWOFSA-N)
Structure
SMILES
OC(=O)C[C@@H](C[C@@H](/C=C/c1c(c2ccc(cc2)F)c2c(n1C(C)C)cccc2)O)O
Molecular Formula:
C24H26FNO4
Molecular Weight:
411.466
Log P:
4.6281
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
3
TPSA:
82.69
CAS Number(s):
93957-54-1
Synonym(s)
1.
Fluvastatin
2.
7-(3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoate
3.
Fluindostatin
4.
Fluvastatin Sodium
5.
Fluvastatin Sodium Salt
6.
Lescol
7.
XU 62-320
8.
XU 62320
9.
XU-62320
10.
XU 62 320
11.
XU62320
External Link(s)
MeSHD000077340
PubChem Compound446155
BindingDB86704
ChEBI38565
93160
IUPHAR/BPS Guide to PHARMACOLOGY2951
Therapeutic Target DatabaseD08GHB
ZINC1886617
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1MyalgiaFAERS: 27SIDER
US FAERS
2Blood creatine phosphokinase increasedFAERS: 11OFFSIDES
SIDER
US FAERS
3Blood cholesterol increasedFAERS: 7US FAERS
4ArthralgiaFAERS: 5SIDER
US FAERS
5AstheniaFAERS: 5OFFSIDES
SIDER
US FAERS
6Abdominal PainFAERS: 424451297CTD
OFFSIDES
SIDER
US FAERS
7Alanine Aminotransferase IncreasedFAERS: 4OFFSIDES
US FAERS
8Aspartate Aminotransferase IncreasedFAERS: 4US FAERS
9MalaiseFAERS: 4SIDER
US FAERS
10RhabdomyolysisFAERS: 4OFFSIDES
SIDER
US FAERS
11Aortic valve calcificationFAERS: 3US FAERS
12Autoimmune hepatitisFAERS: 3US FAERS
13Cerebrovascular accidentFAERS: 3US FAERS
14CholestasisFAERS: 3US FAERS
15Drug dose omissionFAERS: 3US FAERS
16FatigueFAERS: 3OFFSIDES
SIDER
US FAERS
17Gamma-Glutamyltransferase IncreasedFAERS: 3OFFSIDES
US FAERS
18HypersensitivityFAERS: 3SIDER
US FAERS
19MyopathyFAERS: 3SIDER
US FAERS
20MyositisFAERS: 3SIDER
US FAERS
21PainFAERS: 316433891CTD
OFFSIDES
SIDER
US FAERS
22VomitingFAERS: 3SIDER
US FAERS
23Blood alkaline phosphatase increasedFAERS: 2US FAERS
24Cell DeathFAERS: 2OFFSIDES
US FAERS
25Drug ineffectiveFAERS: 2US FAERS
26Eosinophilic PneumoniaFAERS: 2US FAERS
27ErythemaFAERS: 2OFFSIDES
SIDER
US FAERS
28InflammationFAERS: 2US FAERS
29NauseaFAERS: 224451297CTD
OFFSIDES
SIDER
US FAERS
30Trigeminal NeuralgiaFAERS: 2US FAERS
31AbasiaFAERS: 1US FAERS
32Activities of daily living impairedFAERS: 1US FAERS
33Acute kidney injuryFAERS: 1US FAERS
34AgitationFAERS: 1US FAERS
35Alanine aminotransferase abnormalFAERS: 1US FAERS
36Anti-thyroid antibody positiveFAERS: 1US FAERS
37AnxietyFAERS: 1OFFSIDES
SIDER
US FAERS
38AphoniaFAERS: 1US FAERS
39Aspartate aminotransferase abnormalFAERS: 1US FAERS
40AsthmaFAERS: 1OFFSIDES
US FAERS
41Blood creatine phosphokinase MB increasedFAERS: 1US FAERS
42Burning sensationFAERS: 1OFFSIDES
US FAERS
43CellulitisFAERS: 1OFFSIDES
US FAERS
44Chest PainFAERS: 1OFFSIDES
SIDER
US FAERS
45Cholestatic liver injuryFAERS: 1US FAERS
46DehydrationFAERS: 1OFFSIDES
US FAERS
47DiplopiaFAERS: 1OFFSIDES
US FAERS
48DisorientationFAERS: 1US FAERS
49DizzinessFAERS: 1SIDER
US FAERS
50DyspepsiaFAERS: 18017468CTD
SIDER
US FAERS
51DysuriaFAERS: 1US FAERS
52Eosinophilic FasciitisFAERS: 1US FAERS
53FasciitisFAERS: 1US FAERS
54Gamma-glutamyltransferase abnormalFAERS: 1US FAERS
55General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
56HLA marker studyFAERS: 1US FAERS
57Hepatitis B virus test positiveFAERS: 1US FAERS
58Hepatitis C virus test positiveFAERS: 1US FAERS
59HypokinesiaFAERS: 1US FAERS
60Inappropriate schedule of product administrationFAERS: 1US FAERS
61Intermittent ClaudicationFAERS: 1OFFSIDES
SIDER
US FAERS
62Low density lipoprotein increasedFAERS: 1US FAERS
63Macular degenerationFAERS: 1US FAERS
64Mixed liver injuryFAERS: 1US FAERS
65Myocardial InfarctionFAERS: 118384769CTD
US FAERS
66MyosclerosisFAERS: 1US FAERS
67OsteolysisFAERS: 1US FAERS
68PalpitationsFAERS: 1US FAERS
69Peripheral swellingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
70Perivascular dermatitisFAERS: 1US FAERS
71PneumoniaFAERS: 1US FAERS
72Post procedural strokeFAERS: 1US FAERS
73Product physical issueFAERS: 1US FAERS
74Product quality issueFAERS: 1US FAERS
75Product taste abnormalFAERS: 1US FAERS
76SclerodermaFAERS: 1US FAERS
77SepsisFAERS: 1US FAERS
78SomnolenceFAERS: 1US FAERS
79SwellingFAERS: 1US FAERS
80Transaminases increasedFAERS: 1OFFSIDES
SIDER
US FAERS
81Abdominal discomfortOFFSIDES
82Abnormal visionSIDER
83AcidosisOFFSIDES
84Actinic keratosisOFFSIDES
85Acute Coronary SyndromeOFFSIDES
86Acute bronchitisOFFSIDES
87Acute sinusitisOFFSIDES
88AdenocarcinomaOFFSIDES
89AdenomaOFFSIDES
90AgraphiaOFFSIDES
91Aldolase increasedOFFSIDES
92AlopeciaSIDER
93AlveoloplastyOFFSIDES
94AmnesiaSIDER
95AmyloidosisOFFSIDES
96Anal FissureOFFSIDES
97Anal polypOFFSIDES
98Anaphylactic shockSIDER
99Angina Pectoris8017468CTD
100AngioedemaSIDER
101AnhedoniaOFFSIDES
102Ankle FractureOFFSIDES
103Anorexia24451297CTD
OFFSIDES
SIDER
104Aortic valve sclerosisOFFSIDES
105ApathyOFFSIDES
106AppendicitisOFFSIDES
107ArthritisSIDER
108ArthropathyOFFSIDES
SIDER
109Atherosclerosis9818470
20298932		CTD
110Atrial FibrillationSIDER
111AuraOFFSIDES
112Back PainSIDER
113Bacterial Infections12669766CTD
114Band neutrophil percentage decreasedOFFSIDES
115Band neutrophil percentage increasedOFFSIDES
116Biopsy muscle abnormalOFFSIDES
117Bipolar DisorderOFFSIDES
118Blast cell count increasedOFFSIDES
119Blood GlucoseOFFSIDES
120Blood albumin decreasedOFFSIDES
121Blood and lymphatic system disordersSIDER
122Blood beta-D-glucan increasedOFFSIDES
123Blood chloride decreasedOFFSIDES
124Blood cholesterolOFFSIDES
125Blood creatine phosphokinase decreasedOFFSIDES
126Blood creatinine increasedOFFSIDES
127Blood glucose decreasedOFFSIDES
128Blood immunoglobulin A increasedOFFSIDES
129Blood lactate dehydrogenase increasedOFFSIDES
130Blood pH decreasedOFFSIDES
131Blood sodiumOFFSIDES
132Blood urine presentOFFSIDES
133Bone lesionOFFSIDES
134Bone painOFFSIDES
135Borderline Personality DisorderOFFSIDES
136BradycardiaOFFSIDES
137Brain scan abnormalOFFSIDES
138Breast MicrocalcificationOFFSIDES
139BronchitisSIDER
140BronchopneumoniaOFFSIDES
141Cardiac FlutterOFFSIDES
142Cardiomyopathies19147586CTD
143Cardiovascular Diseases10402106CTD
144Cataract operationOFFSIDES
145CataractOFFSIDES
SIDER
146Cerebellar infarctionOFFSIDES
147Cerebral atrophyOFFSIDES
148Chemical and Drug Induced Liver Injury24451297CTD
149ChillsSIDER
150Chronic sinusitisOFFSIDES
151Compression fractureOFFSIDES
152ConfabulationOFFSIDES
153ConjunctivitisSIDER
154ConstipationSIDER
155Coronary artery insufficiencyOFFSIDES
156DemyelinationOFFSIDES
157Depressed Level of ConsciousnessOFFSIDES
158DermatitisSIDER
159Dermatomyositis16446645CTD
OFFSIDES
160Device malfunctionOFFSIDES
161DiabetesOFFSIDES
162Diabetic Neuropathies16696316CTD
163Diabetic RetinopathyOFFSIDES
164DiarrheaOFFSIDES
165DiscomfortSIDER
166Disease ProgressionOFFSIDES
167DiverticulitisOFFSIDES
168Drug withdrawal headacheOFFSIDES
169Dry skinOFFSIDES
170DysgeusiaSIDER
171Dyslipidemias16446645CTD
172DysmenorrheaOFFSIDES
173DysphoniaOFFSIDES
174EczemaSIDER
175Electrocardiogram repolarisation abnormalityOFFSIDES
176Electromechanical dissociationOFFSIDES
177EncephalomalaciaOFFSIDES
178Endoscopic Retrograde CholangiopancreatographyOFFSIDES
179EosinophiliaSIDER
180Erectile dysfunctionSIDER
181EructationSIDER
182Erythema MultiformeSIDER
183ExcoriationOFFSIDES
184Exploratory operationOFFSIDES
185Facial NeuralgiaOFFSIDES
186Facial ParesisSIDER
187Fatty LiverOFFSIDES
188Feeling abnormalSIDER
189FlatulenceOFFSIDES
SIDER
190Fluid overloadOFFSIDES
191FlushingSIDER
192Focal glomerulosclerosisOFFSIDES
193GamblingOFFSIDES
194GastritisSIDER
195Gastrointestinal PainSIDER
196Gingival erythemaOFFSIDES
197GliosisOFFSIDES
198GlobulinuriaOFFSIDES
199GlossoptosisOFFSIDES
200Granulocyte count decreasedOFFSIDES
201Hay feverOFFSIDES
202Headache8017468CTD
SIDER
203Heart failure18384769CTD
204HeartburnSIDER
205Hepatic necrosisSIDER
206Hepatitis B positiveOFFSIDES
207Hepatitis C17420205CTD
208HepatitisSIDER
209Hepatomegaly27369808CTD
210HepatotoxicityOFFSIDES
211HydrocephalusOFFSIDES
212Hypercholesterolemia

View details

8017468
8593127
10027656
10780315
12072574
16618834
 		CTD
213HyperreflexiaOFFSIDES
214Hypersensitive syndromeSIDER
215Hypertriglyceridemia10780315CTD
216Hypotension, Orthostatic9518913CTD
217Ileal ulcerOFFSIDES
218Impaired driving abilityOFFSIDES
219Incisional herniaOFFSIDES
220InfectionSIDER
221InfestationSIDER
222Influenza-like symptomsSIDER
223InfluenzaSIDER
224Infusion site mobility decreasedOFFSIDES
225Intervertebral Disc DegenerationOFFSIDES
226Intervertebral disc disorderOFFSIDES
227Intestinal hypomotilityOFFSIDES
228IntussusceptionOFFSIDES
229Joint Range of Motion DecreasedOFFSIDES
230Leukopenia neonatalOFFSIDES
231LeukopeniaSIDER
232Limb discomfortOFFSIDES
233Limb operationOFFSIDES
234Lip erosionOFFSIDES
235Lupus ErythematosusSIDER
236Memory LossSIDER
237Memory impairmentSIDER
238Middle insomniaOFFSIDES
239Mouth BreathingOFFSIDES
240Mucosal erosionOFFSIDES
241Multiple Myeloma16996129CTD
OFFSIDES
242Muscle FatigueOFFSIDES
243Muscle WeaknessOFFSIDES
244Muscle tightnessOFFSIDES
245Musculoskeletal discomfortSIDER
246Musculoskeletal stiffnessOFFSIDES
247Mycosis FungoidesOFFSIDES
248Myocardial Reperfusion Injury28951255CTD
249Myoglobin blood increasedOFFSIDES
250Myoglobin urine presentSIDER
251MyoglobinuriaSIDER
252MyopiaOFFSIDES
253NasopharyngitisSIDER
254Necrosis20668001CTD
255Neoplasm Invasiveness24964743CTD
256Nephrogenic Fibrosing DermopathyOFFSIDES
257Neuroleptic Malignant SyndromeOFFSIDES
258NoduleSIDER
259Non-cardiac chest painOFFSIDES
260OphthalmoplegiaSIDER
261Optic Disc EdemaOFFSIDES
262Optic NeuritisOFFSIDES
263Oropharyngeal painOFFSIDES
264OsteopeniaOFFSIDES
265OverdoseOFFSIDES
266PancreatitisSIDER
267ParotitisOFFSIDES
268PeriodontitisOFFSIDES
269Peripheral arterial occlusive diseaseOFFSIDES
270Peripheral nerve palsySIDER
271PeritonitisOFFSIDES
272Phantom painOFFSIDES
273PharyngitisSIDER
274Pharyngolaryngeal PainOFFSIDES
275PhlebitisOFFSIDES
276PleurodesisOFFSIDES
277Pneumocystis jiroveci pneumoniaOFFSIDES
278PneumothoraxOFFSIDES
279Polymyalgia RheumaticaSIDER
280Productive CoughOFFSIDES
281Proteinuria16452496CTD
282PruritusSIDER
283Pulmonary HypertensionOFFSIDES
284PurpuraSIDER
285Pustular psoriasisOFFSIDES
286Pyloric StenosisOFFSIDES
287Radical prostatectomyOFFSIDES
288Renal artery stent placementOFFSIDES
289Reticulocyte count decreasedOFFSIDES
290RhinitisSIDER
291Seizures16111706CTD
292Septic ShockOFFSIDES
293SequestrectomyOFFSIDES
294ShockSIDER
295Sick Sinus SyndromeOFFSIDES
296Sinus bradycardiaOFFSIDES
297SinusitisSIDER
298Sjogren's SyndromeOFFSIDES
299Skeletal survey abnormalOFFSIDES
300Skin IndurationOFFSIDES
301Skin tightnessOFFSIDES
302Spinal column stenosisOFFSIDES
303SpondylitisOFFSIDES
304Stevens-Johnson Syndrome25811541CTD
SIDER
305SweatingSIDER
306SyncopeSIDER
307Synovial CystOFFSIDES
308Therapeutic response unexpectedOFFSIDES
309ThrombocytopeniaSIDER
310Tinea PedisOFFSIDES
311Tooth ExtractionOFFSIDES
312Toxic Epidermal NecrolysisSIDER
313TracheobronchitisOFFSIDES
314TraumaSIDER
315TremorSIDER
316Troponin I increasedOFFSIDES
317Urinary tract infectionSIDER
318UrticariaSIDER
319VIIth nerve paralysisSIDER
320Vascular purpuraSIDER
321VasculitisSIDER
322VertebroplastyOFFSIDES
323VertigoSIDER
324Visual ImpairmentSIDER
325Vitamin A DeficiencyOFFSIDES
326Walking aid userOFFSIDES
327Weight Gain27369808CTD
OFFSIDES
328kyphosisOFFSIDES
329nervous system disorderSIDER
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