MetaADEDB 2.0 @ LMMD
Tazobactam
(LPQZKKCYTLCDGQ-WEDXCCLWSA-N)
Structure
SMILES
OC(=O)[C@@H]1N2C(=O)C[C@H]2S(=O)(=O)[C@@]1(C)Cn1ccnn1
Type(s)
Approved
ATC code(s)
J01CG02
Molecular Formula:
C10H12N4O5S
Molecular Weight:
300.291
Log P:
-0.5045
Hydrogen Bond Acceptor:
9
Hydrogen Bond Donor:
1
TPSA:
130.84
CAS Number(s):
89786-04-9
Synonym(s)
1.
Tazobactam
2.
Tazobactam Sodium
3.
YTR 830
4.
YTR 830H
5.
YTR-830
6.
YTR830
External Link(s)
MeSHD000078142
PubChem Compound123630
BindingDB50053173
ChEBI9421
CHEMBLCHEMBL404
DrugBankDB01606
DrugCentral2572
KEGGcpd:C07771
dr:D00660
Therapeutic Target DatabaseD0QQ7D
ZINC3787060
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1PruritusFAERS: 26US FAERS
2NeutropeniaFAERS: 24US FAERS
3ThrombocytopeniaFAERS: 24US FAERS
4HypersensitivityFAERS: 20US FAERS
5UrticariaFAERS: 17US FAERS
6White blood cell count decreasedFAERS: 16US FAERS
7Alanine Aminotransferase IncreasedFAERS: 14OFFSIDES
US FAERS
8LeukopeniaFAERS: 14US FAERS
9Toxic Epidermal NecrolysisFAERS: 14US FAERS
10Aspartate Aminotransferase IncreasedFAERS: 13US FAERS
11PancytopeniaFAERS: 13US FAERS
12ChillsFAERS: 12US FAERS
13NauseaFAERS: 12US FAERS
14VomitingFAERS: 12US FAERS
15ErythemaFAERS: 11OFFSIDES
US FAERS
16Medication ErrorFAERS: 10US FAERS
17AgranulocytosisFAERS: 9US FAERS
18Blood creatinine increasedFAERS: 9US FAERS
19RhabdomyolysisFAERS: 9US FAERS
20Stevens-Johnson SyndromeFAERS: 9OFFSIDES
US FAERS
21Disseminated Intravascular CoagulationFAERS: 8US FAERS
22PneumoniaFAERS: 8US FAERS
23Rash erythematousFAERS: 8US FAERS
24Drug ineffectiveFAERS: 7US FAERS
25Renal tubular necrosisFAERS: 7OFFSIDES
US FAERS
26SepsisFAERS: 7US FAERS
27Blood alkaline phosphatase increasedFAERS: 6OFFSIDES
US FAERS
28FlushingFAERS: 6US FAERS
29HeadacheFAERS: 6US FAERS
30HypotensionFAERS: 6US FAERS
31TachycardiaFAERS: 6US FAERS
32Acute kidney injuryFAERS: 5US FAERS
33Anaphylactoid ReactionFAERS: 5US FAERS
34Circumstance or information capable of leading to medication errorFAERS: 5US FAERS
35Clostridium difficile colitisFAERS: 5OFFSIDES
US FAERS
36HepatitisFAERS: 5OFFSIDES
US FAERS
37Infusion Site ExtravasationFAERS: 5US FAERS
38MalaiseFAERS: 5US FAERS
39MyalgiaFAERS: 5US FAERS
40Oropharyngeal painFAERS: 5US FAERS
41Respiratory FailureFAERS: 5US FAERS
42TremorFAERS: 5US FAERS
43Anaphylactic shockFAERS: 4US FAERS
44AstheniaFAERS: 4US FAERS
45Cardiac ArrestFAERS: 4US FAERS
46Documented hypersensitivity to administered drugFAERS: 4US FAERS
47ExtravasationFAERS: 4US FAERS
48Neutrophil count decreasedFAERS: 4US FAERS
49No adverse eventFAERS: 4US FAERS
50Pharmaceutical product complaintFAERS: 4US FAERS
51SwellingFAERS: 4US FAERS
52Abdominal discomfortFAERS: 3US FAERS
53Accidental exposure to productFAERS: 3US FAERS
54AlopeciaFAERS: 3US FAERS
55AnxietyFAERS: 3US FAERS
56Chest PainFAERS: 3US FAERS
57CholestasisFAERS: 3US FAERS
58Concomitant disease progressionFAERS: 3US FAERS
59Drug toxicityFAERS: 3US FAERS
60EosinophiliaFAERS: 3US FAERS
61False positive investigation resultFAERS: 3US FAERS
62Feeling abnormalFAERS: 3US FAERS
63Gamma-Glutamyltransferase IncreasedFAERS: 3OFFSIDES
US FAERS
64Histiocytosis haematophagicFAERS: 3OFFSIDES
US FAERS
65Injection site erythemaFAERS: 3US FAERS
66Injection site painFAERS: 3US FAERS
67LymphadenopathyFAERS: 3US FAERS
68Metabolic acidosisFAERS: 3OFFSIDES
US FAERS
69Oropharyngeal discomfortFAERS: 3US FAERS
70Product quality issueFAERS: 3US FAERS
71pseudomembranous colitisFAERS: 3US FAERS
72Abdominal PainFAERS: 2US FAERS
73Atrial FibrillationFAERS: 2US FAERS
74BradycardiaFAERS: 2US FAERS
75Catheter related infectionFAERS: 2US FAERS
76CholelithiasisFAERS: 2US FAERS
77DeliriumFAERS: 2US FAERS
78Depressed Level of ConsciousnessFAERS: 2US FAERS
79DermatitisFAERS: 2US FAERS
80DiscomfortFAERS: 2US FAERS
81DizzinessFAERS: 2US FAERS
82DysphoniaFAERS: 2US FAERS
83Eosinophils urine presentFAERS: 2US FAERS
84EpistaxisFAERS: 2US FAERS
85FatigueFAERS: 2US FAERS
86Febrile NeutropeniaFAERS: 2OFFSIDES
US FAERS
87Incorrect drug administration rateFAERS: 2US FAERS
88Incorrect route of drug administrationFAERS: 2US FAERS
89Injection site extravasationFAERS: 2US FAERS
90Joint swellingFAERS: 2US FAERS
91Leukocytoclastic vasculitisFAERS: 2US FAERS
92Mental status changesFAERS: 2US FAERS
93Nonspecific reactionFAERS: 2US FAERS
94Occupational exposure to productFAERS: 2US FAERS
95PainFAERS: 2US FAERS
96PallorFAERS: 2US FAERS
97PalpitationsFAERS: 2US FAERS
98PneumonitisFAERS: 2US FAERS
99Product use issueFAERS: 2US FAERS
100Pulmonary congestionFAERS: 2US FAERS
101Respiratory distressFAERS: 2US FAERS
102ShockFAERS: 2US FAERS
103Skin UlcerFAERS: 2US FAERS
104Unevaluable eventFAERS: 2US FAERS
105Unresponsive to stimuliFAERS: 2US FAERS
106Urinary tract infectionFAERS: 2US FAERS
107Ventricular FibrillationFAERS: 2US FAERS
108WheezingFAERS: 2US FAERS
109jaundiceFAERS: 2US FAERS
110Accidental exposureFAERS: 1US FAERS
111Accidental overdoseFAERS: 1OFFSIDES
US FAERS
112Administration site necrosisFAERS: 1US FAERS
113AgeusiaFAERS: 1US FAERS
114AgitationFAERS: 1US FAERS
115Alcohol withdrawal syndromeFAERS: 1US FAERS
116Allergic respiratory symptomFAERS: 1US FAERS
117Altered state of consciousnessFAERS: 1US FAERS
118Angina PectorisFAERS: 1US FAERS
119AngioedemaFAERS: 1OFFSIDES
US FAERS
120AnorexiaFAERS: 1US FAERS
121AnosmiaFAERS: 1US FAERS
122Anti factor V antibody positiveFAERS: 1US FAERS
123AnuriaFAERS: 1OFFSIDES
US FAERS
124Apparent deathFAERS: 1US FAERS
125AppendicitisFAERS: 1US FAERS
126ArthralgiaFAERS: 1US FAERS
127ArthritisFAERS: 1US FAERS
128AsphyxiaFAERS: 1US FAERS
129Atrial conduction time prolongationFAERS: 1US FAERS
130Autoimmune thrombocytopeniaFAERS: 1US FAERS
131Back PainFAERS: 1US FAERS
132BlindnessFAERS: 1US FAERS
133Blood creatine phosphokinase increasedFAERS: 1US FAERS
134Blood electrolytes abnormalFAERS: 1US FAERS
135Blood magnesium decreasedFAERS: 1US FAERS
136Blood potassium increasedFAERS: 1US FAERS
137Blood pressure fluctuationFAERS: 1US FAERS
138Blood pressure immeasurableFAERS: 1US FAERS
139Bone painFAERS: 1US FAERS
140Brain HypoxiaFAERS: 1US FAERS
141Catheter site rashFAERS: 1US FAERS
142CellulitisFAERS: 1US FAERS
143CheilitisFAERS: 1OFFSIDES
US FAERS
144Chest discomfortFAERS: 1US FAERS
145CholecystitisFAERS: 1OFFSIDES
US FAERS
146ChromaturiaFAERS: 1US FAERS
147Clostridium colitisFAERS: 1US FAERS
148Clostridium difficile infectionFAERS: 1US FAERS
149Clostridium test positiveFAERS: 1US FAERS
150Creatinine renal clearance decreasedFAERS: 1US FAERS
151DeafnessFAERS: 1US FAERS
152Deep Vein ThrombosisFAERS: 1US FAERS
153Device difficult to useFAERS: 1US FAERS
154Device infusion issueFAERS: 1US FAERS
155Diabetes MellitusFAERS: 1US FAERS
156Drug administration errorFAERS: 1US FAERS
157Drug dose omissionFAERS: 1US FAERS
158Drug prescribing errorFAERS: 1US FAERS
159Dry skinFAERS: 1US FAERS
160DystoniaFAERS: 1US FAERS
161Electrocardiogram abnormalFAERS: 1US FAERS
162Electromechanical dissociationFAERS: 1US FAERS
163Exposure during breast feedingFAERS: 1US FAERS
164Extra dose administeredFAERS: 1US FAERS
165Factor V inhibitionFAERS: 1US FAERS
166Fibrin D dimer increasedFAERS: 1US FAERS
167Fluid overloadFAERS: 1US FAERS
168Gastrointestinal PainFAERS: 1US FAERS
169General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
170Granulocyte count decreasedFAERS: 1US FAERS
171GranulocytosisFAERS: 1US FAERS
172HyperpyrexiaFAERS: 1US FAERS
173HypersomniaFAERS: 1US FAERS
174HypogeusiaFAERS: 1US FAERS
175HypoventilationFAERS: 1US FAERS
176HypoxiaFAERS: 1OFFSIDES
US FAERS
177Iatrogenic injuryFAERS: 1US FAERS
178Incorrect dose administeredFAERS: 1US FAERS
179Incorrect drug administration durationFAERS: 1US FAERS
180Infusion site erythemaFAERS: 1US FAERS
181Injection site inflammationFAERS: 1US FAERS
182Injection site pruritusFAERS: 1US FAERS
183Injection site pustuleFAERS: 1US FAERS
184Injury associated with deviceFAERS: 1US FAERS
185Intercepted drug administration errorFAERS: 1US FAERS
186Intestinal PerforationFAERS: 1US FAERS
187LacerationFAERS: 1US FAERS
188LethargyFAERS: 1US FAERS
189LeukocytosisFAERS: 1US FAERS
190Limb injuryFAERS: 1US FAERS
191Lip swellingFAERS: 1US FAERS
192Long QT SyndromeFAERS: 1US FAERS
193LymphadenitisFAERS: 1US FAERS
194Lymphomatoid PapulosisFAERS: 1US FAERS
195MalabsorptionFAERS: 1US FAERS
196Medical device complicationFAERS: 1US FAERS
197MeningiomaFAERS: 1US FAERS
198Murphy's sign positiveFAERS: 1US FAERS
199Myocardial InfarctionFAERS: 1US FAERS
200MyositisFAERS: 1US FAERS
201Neutrophil count abnormalFAERS: 1US FAERS
202Nodular rashFAERS: 1US FAERS
203OliguriaFAERS: 1OFFSIDES
US FAERS
204Oral fungal infectionFAERS: 1US FAERS
205OverdoseFAERS: 1OFFSIDES
US FAERS
206Pancreatic PseudocystFAERS: 1US FAERS
207PancreatitisFAERS: 1US FAERS
208Peripheral swellingFAERS: 1US FAERS
209Product barcode issueFAERS: 1US FAERS
210Product container issueFAERS: 1US FAERS
211Product depositFAERS: 1US FAERS
212Product label confusionFAERS: 1US FAERS
213Prothrombin time abnormalFAERS: 1US FAERS
214Pulmonary EosinophiliaFAERS: 1US FAERS
215Renal painFAERS: 1US FAERS
216Respiratory arrestFAERS: 1US FAERS
217ScabFAERS: 1US FAERS
218Septic ShockFAERS: 1OFFSIDES
US FAERS
219Serum SicknessFAERS: 1OFFSIDES
US FAERS
220Similar reaction on previous exposure to drugFAERS: 1US FAERS
221Sinus ArrhythmiaFAERS: 1US FAERS
222Skin irritationFAERS: 1US FAERS
223Skin reactionFAERS: 1US FAERS
224SomnolenceFAERS: 1US FAERS
225Stasis dermatitisFAERS: 1US FAERS
226Therapy changeFAERS: 1US FAERS
227Throat irritationFAERS: 1US FAERS
228ThrombosisFAERS: 1US FAERS
229TinnitusFAERS: 1US FAERS
230Tonic clonic movementsFAERS: 1OFFSIDES
US FAERS
231Transaminases increasedFAERS: 1OFFSIDES
US FAERS
232Urinary RetentionFAERS: 1US FAERS
233Vaginal mycosisFAERS: 1US FAERS
234Vitamin K DeficiencyFAERS: 1US FAERS
235Weight decreasedFAERS: 1US FAERS
236White blood cell count abnormalFAERS: 1US FAERS
237Abdominal adhesionsOFFSIDES
238Abdominal massOFFSIDES
239AbscessOFFSIDES
240Acid fast bacilli infectionOFFSIDES
241AcidosisOFFSIDES
242ActinomycosisOFFSIDES
243Acute respiratory failureOFFSIDES
244AdenitisOFFSIDES
245Alcoholic IntoxicationOFFSIDES
246Alternaria infectionOFFSIDES
247AlveolitisOFFSIDES
248AngiodysplasiaOFFSIDES
249Antibiotic level above therapeuticOFFSIDES
250Anticholinergic SyndromeOFFSIDES
251Anticoagulation drug level above therapeuticOFFSIDES
252Apolipoprotein increasedOFFSIDES
253AspergillosisOFFSIDES
254Aspiration PneumoniaOFFSIDES
255AuraOFFSIDES
256Bacterial test positiveOFFSIDES
257BicytopeniaOFFSIDES
258Biliary adenomaOFFSIDES
259Bilirubin conjugated increasedOFFSIDES
260BiopsyOFFSIDES
261Blast cell count increasedOFFSIDES
262Blood amylase increasedOFFSIDES
263Blood glucose decreasedOFFSIDES
264Blood phosphorus increasedOFFSIDES
265Blood sodium increasedOFFSIDES
266Bone marrow depressionOFFSIDES
267Bronchial ObstructionOFFSIDES
268Bronchoalveolar LavageOFFSIDES
269Candida sepsisOFFSIDES
270Cardioactive drug levelOFFSIDES
271Catheter site cellulitisOFFSIDES
272Catheter site inflammationOFFSIDES
273Cerebral atrophyOFFSIDES
274Chemotherapeutic drug level increasedOFFSIDES
275CholangiolitisOFFSIDES
276Coagulation factor V level decreasedOFFSIDES
277ColectomyOFFSIDES
278ColitisOFFSIDES
279ConfabulationOFFSIDES
280CyanosisOFFSIDES
281Cystitis escherichiaOFFSIDES
282Cytolytic hepatitisOFFSIDES
283Cytomegalovirus test positiveOFFSIDES
284Decreased insulin requirementOFFSIDES
285DemyelinationOFFSIDES
286Drug level below therapeuticOFFSIDES
287DyslaliaOFFSIDES
288Enamel anomalyOFFSIDES
289EncephalitisOFFSIDES
290Enterococcal infectionOFFSIDES
291Enterococcal sepsisOFFSIDES
292Epidermal necrosisOFFSIDES
293EpilepsyOFFSIDES
294Epstein-Barr virus antibody positiveOFFSIDES
295ErysipelasOFFSIDES
296Escherichia infectionOFFSIDES
297Escherichia sepsisOFFSIDES
298Escherichia urinary tract infectionOFFSIDES
299Esophageal StenosisOFFSIDES
300Exfoliative rashOFFSIDES
301Extremity contractureOFFSIDES
302Extremity necrosisOFFSIDES
303Factor V deficiencyOFFSIDES
304Failure to anastomoseOFFSIDES
305Fatty LiverOFFSIDES
306Febrile bone marrow aplasiaOFFSIDES
307GammopathyOFFSIDES
308GastroenteritisOFFSIDES
309Gastrointestinal obstructionOFFSIDES
310Granulocytes maturation arrestOFFSIDES
311HemiplegiaOFFSIDES
312Hepatic artery thrombosisOFFSIDES
313Hepatitis COFFSIDES
314HepatosplenomegalyOFFSIDES
315HepatotoxicityOFFSIDES
316HistologyOFFSIDES
317Human herpesvirus 8 infectionOFFSIDES
318HypercapniaOFFSIDES
319Immune reconstitution syndromeOFFSIDES
320Immunosuppressant drug level decreasedOFFSIDES
321InfectionOFFSIDES
322IntubationOFFSIDES
323Kidney FailureOFFSIDES
324LaparotomyOFFSIDES
325LeukoencephalopathyOFFSIDES
326Leukopenia neonatalOFFSIDES
327LeukoplakiaOFFSIDES
328Lip erosionOFFSIDES
329LipaseOFFSIDES
330Livedo ReticularisOFFSIDES
331Liver AbscessOFFSIDES
332Liver transplant rejectionOFFSIDES
333Loose toothOFFSIDES
334LymphedemaOFFSIDES
335LymphoceleOFFSIDES
336Lymphocytic dermatitisOFFSIDES
337Lymphocytic infiltrationOFFSIDES
338MegacolonOFFSIDES
339MeningorrhagiaOFFSIDES
340Mixed liver injuryOFFSIDES
341Mononucleosis syndromeOFFSIDES
342Motor retardationOFFSIDES
343MutismOFFSIDES
344Myeloid maturation arrestOFFSIDES
345Neurological decompensationOFFSIDES
346Oral mucosa atrophyOFFSIDES
347OsteolysisOFFSIDES
348OsteosclerosisOFFSIDES
349PO2 abnormalOFFSIDES
350PROTHROMBIN TIMEOFFSIDES
351Pancreatic enzymes increasedOFFSIDES
352Pelvic InfectionOFFSIDES
353Peptostreptococcus infectionOFFSIDES
354PericarditisOFFSIDES
355PeriodontitisOFFSIDES
356Peritoneal lavageOFFSIDES
357Peritonitis16369182CTD
OFFSIDES
358Perivascular dermatitisOFFSIDES
359PleurisyOFFSIDES
360PneumothoraxOFFSIDES
361Portal HypertensionOFFSIDES
362Portal Vein ThrombosisOFFSIDES
363Postoperative infectionOFFSIDES
364Primary Effusion LymphomaOFFSIDES
365Propofol Infusion SyndromeOFFSIDES
366Pseudomonal sepsisOFFSIDES
367Psychiatric decompensationOFFSIDES
368Puncture site infectionOFFSIDES
369PurulenceOFFSIDES
370ReticulocytosisOFFSIDES
371RetrocollisOFFSIDES
372Rotavirus test positiveOFFSIDES
373Salmonella sepsisOFFSIDES
374SeromaOFFSIDES
375Sinus bradycardiaOFFSIDES
376Skin necrosisOFFSIDES
377Soft Tissue InfectionOFFSIDES
378SplenectomyOFFSIDES
379Status EpilepticusOFFSIDES
380Stem cell transplantOFFSIDES
381Stenotrophomonas infectionOFFSIDES
382SubileusOFFSIDES
383Systemic mycosisOFFSIDES
384Tongue exfoliationOFFSIDES
385Tooth ResorptionOFFSIDES
386Ureteral necrosisOFFSIDES
387Ureterostomy site discomfortOFFSIDES
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