MetaADEDB 2.0 @ LMMD
Etomidate
(NPUKDXXFDDZOKR-UHFFFAOYSA-N)
Structure
SMILES
CCOC(=O)c1cncn1C(c1ccccc1)C
Molecular Formula:
C14H16N2O2
Molecular Weight:
244.289
Log P:
2.6691
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
0
TPSA:
44.12
CAS Number(s):
15301-65-2; 33125-97-2
Synonym(s)
1.
Etomidate
2.
Ethomidate
3.
Hypnomidate
4.
R-26490
5.
Radenarkon
6.
R 26490
7.
R26490
External Link(s)
MeSHD005045
PubChem Compound36339
BindingDB238149
ChEBI91759
CHEMBLCHEMBL23731
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 9US FAERS
2Injection site phlebitisFAERS: 5OFFSIDES
US FAERS
3Product quality issueFAERS: 4US FAERS
4TremorFAERS: 43344940CTD
US FAERS
5Infusion site thrombosisFAERS: 3US FAERS
6Medication ErrorFAERS: 3US FAERS
7MyoclonusFAERS: 3

View details

526383
612112
1015219
1015239
2207824
3354919
3621016
3752481
3966657
4025853
4025859
4083468
6148025
6322557
6696228
7027723
8214699
9915320
10513376
12635389
12694150
14652121
14655236
15167427
15295244
16115978
16548978
16563323
16914464
16997421
16997680
17005362
17471876
17959958
18230263
19100933
20018300
20108006
24535067
 		CTD
SIDER
US FAERS
8PhlebitisFAERS: 36108669CTD
OFFSIDES
US FAERS
9AgitationFAERS: 2US FAERS
10BruxismFAERS: 2OFFSIDES
US FAERS
11Cardiac ArrestFAERS: 2US FAERS
12Eye painFAERS: 2US FAERS
13HypotensionFAERS: 2
Canada Vigilance: 1

View details

2207824
9796607
10698137
15295727
15496697
 		CTD
SIDER
Canada Vigilance
US FAERS
14HypoxiaFAERS: 2OFFSIDES
SIDER
US FAERS
15Incorrect route of drug administrationFAERS: 2US FAERS
16Intubation complicationFAERS: 2US FAERS
17Retinal Artery OcclusionFAERS: 2US FAERS
18ScreamingFAERS: 2US FAERS
19ThrombophlebitisFAERS: 2

View details

2178488
2278365
2675669
6108669
6691878
 		CTD
US FAERS
20Tonic clonic movementsFAERS: 2OFFSIDES
US FAERS
21nervous system disorderFAERS: 2US FAERS
22AmnesiaFAERS: 1US FAERS
23Atrial FibrillationFAERS: 1US FAERS
24BlepharospasmFAERS: 1US FAERS
25BradycardiaFAERS: 12892519
3919609		CTD
OFFSIDES
SIDER
US FAERS
26Brain scan abnormalFAERS: 1US FAERS
27Cerebral InfarctionFAERS: 1US FAERS
28Cerebrovascular accidentFAERS: 1US FAERS
29Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
30Completed SuicideFAERS: 1US FAERS
31Device FailureFAERS: 1US FAERS
32DystoniaFAERS: 1US FAERS
33ErythemaFAERS: 11015219
6743462		CTD
US FAERS
34HypoperfusionFAERS: 1US FAERS
35Infusion Site ExtravasationFAERS: 1US FAERS
36Injection site cellulitisFAERS: 1US FAERS
37Injection site erythemaFAERS: 1US FAERS
38Injection site extravasationFAERS: 1US FAERS
39Injection site painFAERS: 1US FAERS
40Intentional misuseFAERS: 1US FAERS
41Intercepted drug dispensing errorFAERS: 1US FAERS
42LymphangitisFAERS: 1US FAERS
43Metabolic acidosisFAERS: 1US FAERS
44Myoclonic EpilepsyFAERS: 1US FAERS
45Needle issueFAERS: 1US FAERS
46OverdoseFAERS: 1OFFSIDES
US FAERS
47Pacemaker complicationFAERS: 1US FAERS
48Pacemaker generated arrhythmiaFAERS: 1US FAERS
49PainFAERS: 1

View details

339773
526382
526383
612112
1015218
1015219
1015239
2178488
2278365
4025853
6148025
6322557
6650800
6691878
6743462
7457821
10655920
16997680
21056806
 		CTD
OFFSIDES
SIDER
US FAERS
50Pharmaceutical product complaintFAERS: 1US FAERS
51Post procedural complicationFAERS: 1OFFSIDES
US FAERS
52Product label issueFAERS: 1US FAERS
53Product storage errorFAERS: 1US FAERS
54PruritusFAERS: 1US FAERS
55TachycardiaFAERS: 1SIDER
US FAERS
56Therapy cessationFAERS: 1US FAERS
57Toxic Epidermal NecrolysisFAERS: 1US FAERS
58Ventricular FibrillationFAERS: 118334037CTD
OFFSIDES
US FAERS
59Victim of homicideFAERS: 1US FAERS
60Visual ImpairmentFAERS: 1US FAERS
61Abdominal PainOFFSIDES
62Abdominal discomfortOFFSIDES
63AbscessOFFSIDES
64Acidosis7477798
9322462		CTD
OFFSIDES
65Acute respiratory failureOFFSIDES
66Adnexa uteri massOFFSIDES
67AkinesiaOFFSIDES
68Alanine Aminotransferase IncreasedOFFSIDES
69AlopeciaOFFSIDES
70AlveolitisOFFSIDES
71Ammonia increasedOFFSIDES
72AneurysmOFFSIDES
73AngioedemaCanada Vigilance: 13578739CTD
Canada Vigilance
74AnhedoniaOFFSIDES
75Antipsychotic drug level below therapeuticOFFSIDES
76AnxietyOFFSIDES
77Apnea20912
3344940
4025853		CTD
78Aspiration PneumoniaOFFSIDES
79AstheniaOFFSIDES
80AtelectasisOFFSIDES
81Atrial thrombosisOFFSIDES
82Atrioventricular Block18210663CTD
83BelligerenceOFFSIDES
84Bifascicular blockOFFSIDES
85Blood GlucoseOFFSIDES
86Blood chloride decreasedOFFSIDES
87Blood glucose decreasedOFFSIDES
88Blood pH decreasedOFFSIDES
89Blood phosphorus decreasedOFFSIDES
90Blood sodiumOFFSIDES
91Brain Edema7477798CTD
92Brain Ischemia8559304CTD
93Bronchial ObstructionOFFSIDES
94BronchopneumoniaOFFSIDES
95Cardiovascular Abnormalities2742101CTD
96Cardiovascular insufficiencyOFFSIDES
97Catatonia9856742CTD
98Cervicobrachial syndromeOFFSIDES
99Chest PainOFFSIDES
100Choking sensationOFFSIDES
101ClonusOFFSIDES
102DemyelinationOFFSIDES
103Dental abscessOFFSIDES
104Dental cariesOFFSIDES
105DermatomyositisOFFSIDES
106Disseminated Intravascular CoagulationOFFSIDES
107DiverticulosisOFFSIDES
108Drug exposure during pregnancyOFFSIDES
109Drug screen positiveOFFSIDES
110DysphoniaOFFSIDES
111DysuriaOFFSIDES
112Ejection Fraction DecreasedOFFSIDES
113Electromechanical dissociationOFFSIDES
114Emotional distressOFFSIDES
115EndocarditisOFFSIDES
116Enterococcal sepsisOFFSIDES
117Erectile dysfunctionOFFSIDES
118ExcoriationOFFSIDES
119FatigueOFFSIDES
120Feeling ColdOFFSIDES
121FormicationOFFSIDES
122Gamma-Glutamyltransferase IncreasedOFFSIDES
123Gas GangreneOFFSIDES
124Genital erosionOFFSIDES
125Gingival erythemaOFFSIDES
126GlobulinuriaOFFSIDES
127GranulocytosisOFFSIDES
128HaemoconcentrationOFFSIDES
129Hemoglobinuria7898032
8563446		CTD
130Heparin-induced thrombocytopeniaOFFSIDES
131Hepatitis B positiveOFFSIDES
132HepatotoxicityOFFSIDES
133HydrocephalusOFFSIDES
134HydronephrosisOFFSIDES
135Hyperosmolar stateOFFSIDES
136HyperventilationSIDER
137HypoventilationSIDER
138HysterectomyOFFSIDES
139Iliac artery occlusionOFFSIDES
140InfectionOFFSIDES
141Intervertebral Disc DegenerationOFFSIDES
142Intracranial Hypertension7477798CTD
143IntubationOFFSIDES
144Joint sprainOFFSIDES
145Kidney FailureOFFSIDES
146Large intestine perforationOFFSIDES
147LaryngospasmSIDER
148LeukoencephalopathyOFFSIDES
149Live BirthOFFSIDES
150Livedo ReticularisOFFSIDES
151Lung infection pseudomonalOFFSIDES
152LymphoceleOFFSIDES
153Malignant neoplasm progressionOFFSIDES
154Memory Disorders16597725CTD
155Mental status changesOFFSIDES
156MonoplegiaOFFSIDES
157Mucosal erosionOFFSIDES
158Muscle Rigidity3919609CTD
159Muscle WeaknessOFFSIDES
160Musculoskeletal PainOFFSIDES
161Myocardial Ischemia6362477CTD
162Myocardial ruptureOFFSIDES
163NasopharyngitisOFFSIDES
164Nausea7457821CTD
OFFSIDES
165NoduleOFFSIDES
166Nutritional condition abnormalOFFSIDES
167Oral Cavity FistulaOFFSIDES
168OsteolysisOFFSIDES
169PO2 decreasedOFFSIDES
170PityriasisOFFSIDES
171PneumopericardiumOFFSIDES
172PneumothoraxOFFSIDES
173Poor weight gain neonatalOFFSIDES
174Postoperative Nausea and Vomiting3919609
4025853		CTD
175Procedural complicationOFFSIDES
176Procedural nauseaSIDER
177Prostate cancer recurrentOFFSIDES
178Psychomotor Agitation7546752CTD
179Psychotic Disorders7457821CTD
180Pulmonary HypertensionOFFSIDES
181Pulmonary artery thrombosisOFFSIDES
182Purulent dischargeOFFSIDES
183RalesOFFSIDES
184Renal Insufficiency7477798CTD
185Renal artery occlusionOFFSIDES
186Respiratory FailureOFFSIDES
SIDER
187Respiratory Tract Diseases7457821CTD
188Seizures

View details

2978064
3177871
4083468
6136664
11116789
17804993
 		CTD
189Septic ShockOFFSIDES
190Sinus rhythmOFFSIDES
191Skin lacerationOFFSIDES
192Skin necrosisOFFSIDES
193SnoringSIDER
194Spinal column stenosisOFFSIDES
195SpondylolisthesisOFFSIDES
196Status Epilepticus2745868CTD
197Superinfection lungOFFSIDES
198Synovial CystOFFSIDES
199Tachycardia, Ventricular17457141
18334037		CTD
200Thrombosis2278365
6108669		CTD
201Tooth ExtractionOFFSIDES
202Unresponsive to stimuliOFFSIDES
203Upper airway obstructionSIDER
204Urine flow decreasedOFFSIDES
205Urticaria2675669CTD
206Vascular Diseases10655920CTD
207Vascular bypass graftOFFSIDES
208Vascular insufficiencyOFFSIDES
209Vascular painSIDER
210Vein painSIDER
211Vomiting7457821
7546752		CTD
SIDER
212Wound necrosisOFFSIDES
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