cefprozil
(WDLWHQDACQUCJR-ZAMMOSSLSA-N)
Structure
- SMILES
- C/C=C/C1=C(C(=O)O)N2[C@H](SC1)[C@@H](C2=O)NC(=O)[C@@H](c1ccc(cc1)O)N
- Type(s)
- Approved
- ATC code(s)
- J01DC10
- Molecular Formula:
- C18H19N3O5S
- Molecular Weight:
- 389.426
- Log P:
- 1.7358
- Hydrogen Bond Acceptor:
- 9
- Hydrogen Bond Donor:
- 4
- TPSA:
- 158.26
- CAS Number(s):
- 92665-29-7; 92676-86-3
Synonym(s)
1.
cefprozil
2.
7-(2-amino-2-(4-hydroxyphenyl)acetamido)-3-(propenyl)-3-cephem-4-carboxylic acid monohydrate
3.
7-(2-amino-2-(p-hydroxyphenyl)acetamido)-8-oxo-3-(1-propenyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
4.
Arzimol
5.
BMY 28100
6.
BMY-28100
7.
Brisoral
8.
Cefzil
9.
Procef
10.
cefprozil monohydrate
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Vomiting | FAERS: 21 Canada Vigilance: 4 | 17111287 | CTD SIDER Canada Vigilance US FAERS |
| 2 | Drug ineffective | FAERS: 11 | US FAERS | |
| 3 | Erythema | FAERS: 11 Canada Vigilance: 1 | Canada Vigilance OFFSIDES SIDER US FAERS | |
| 4 | Urticaria | FAERS: 9 Canada Vigilance: 3 | Canada Vigilance SIDER US FAERS | |
| 5 | Nausea | FAERS: 8 | OFFSIDES SIDER US FAERS | |
| 6 | Pruritus | FAERS: 6 Canada Vigilance: 4 | Canada Vigilance SIDER US FAERS | |
| 7 | Dysgeusia | FAERS: 5 | US FAERS | |
| 8 | Hypersensitivity | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 9 | Serum Sickness | FAERS: 5 | OFFSIDES SIDER US FAERS | |
| 10 | Abdominal discomfort | FAERS: 4 | OFFSIDES US FAERS | |
| 11 | Arthralgia | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Chromaturia | FAERS: 4 | OFFSIDES US FAERS | |
| 13 | Dizziness | FAERS: 4 | OFFSIDES SIDER US FAERS | |
| 14 | Fatigue | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 15 | Back Pain | FAERS: 3 | US FAERS | |
| 16 | Dehydration | FAERS: 3 | OFFSIDES US FAERS | |
| 17 | Drug resistance | FAERS: 3 | US FAERS | |
| 18 | Lethargy | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 19 | Medication Error | FAERS: 3 | US FAERS | |
| 20 | Myocarditis | FAERS: 3 | 17111287 | CTD US FAERS |
| 21 | Wheezing | FAERS: 3 | US FAERS | |
| 22 | Colitis | FAERS: 2 | SIDER US FAERS | |
| 23 | Erythema Multiforme | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 24 | Headache | FAERS: 2 | SIDER US FAERS | |
| 25 | Hypotension | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 26 | Liver Abscess | FAERS: 2 | OFFSIDES US FAERS | |
| 27 | Mastoiditis | FAERS: 2 | US FAERS | |
| 28 | Mental status changes | FAERS: 2 | OFFSIDES US FAERS | |
| 29 | Myocardial Infarction | FAERS: 2 | US FAERS | |
| 30 | Product storage error | FAERS: 2 | US FAERS | |
| 31 | Swelling | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 32 | Syncope | FAERS: 2 | 17111287 | CTD US FAERS |
| 33 | Toxic Epidermal Necrolysis | FAERS: 2 | SIDER US FAERS | |
| 34 | Urinary tract infection | FAERS: 2 | US FAERS | |
| 35 | Abasia | FAERS: 1 | US FAERS | |
| 36 | Accidental drug intake by child | FAERS: 1 | US FAERS | |
| 37 | Acute respiratory failure | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance OFFSIDES US FAERS | |
| 38 | Adverse event | FAERS: 1 | US FAERS | |
| 39 | Anxiety | FAERS: 1 | OFFSIDES US FAERS | |
| 40 | Asthenia | FAERS: 1 | US FAERS | |
| 41 | Blood urine present | FAERS: 1 | US FAERS | |
| 42 | Cardiomegaly | FAERS: 1 | US FAERS | |
| 43 | Chest Pain | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 44 | Chills | FAERS: 1 | US FAERS | |
| 45 | Circumstance or information capable of leading to medication error | FAERS: 1 | OFFSIDES US FAERS | |
| 46 | Clostridium difficile infection | FAERS: 1 | US FAERS | |
| 47 | Crying | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 48 | Depressed mood | FAERS: 1 | US FAERS | |
| 49 | Drug dose omission | FAERS: 1 | US FAERS | |
| 50 | Ear discomfort | FAERS: 1 | US FAERS | |
| 51 | Ejection Fraction Decreased | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance OFFSIDES US FAERS | |
| 52 | Epistaxis | FAERS: 1 | OFFSIDES US FAERS | |
| 53 | Eye Infection | FAERS: 1 | US FAERS | |
| 54 | Facial Pain | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 55 | Flat affect | FAERS: 1 | US FAERS | |
| 56 | Hepatitis | FAERS: 1 | US FAERS | |
| 57 | Hypophagia | FAERS: 1 | US FAERS | |
| 58 | Impaired driving ability | FAERS: 1 | US FAERS | |
| 59 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 60 | Joint swelling | FAERS: 1 | US FAERS | |
| 61 | Lip swelling | FAERS: 1 | US FAERS | |
| 62 | Malaise | FAERS: 1 | US FAERS | |
| 63 | Middle insomnia | FAERS: 1 | US FAERS | |
| 64 | Mydriasis | FAERS: 1 | US FAERS | |
| 65 | Neuropathy | FAERS: 1 | US FAERS | |
| 66 | No adverse event | FAERS: 1 | US FAERS | |
| 67 | Otitis Media | FAERS: 1 | US FAERS | |
| 68 | Overdose | FAERS: 1 | US FAERS | |
| 69 | Pain | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance OFFSIDES SIDER US FAERS | |
| 70 | Penile exfoliation | FAERS: 1 | US FAERS | |
| 71 | Pharmaceutical product complaint | FAERS: 1 | US FAERS | |
| 72 | Pharmaceutical product counterfeit | FAERS: 1 | US FAERS | |
| 73 | Physical product label issue | FAERS: 1 | US FAERS | |
| 74 | Poor quality drug administered | FAERS: 1 | US FAERS | |
| 75 | Product formulation issue | FAERS: 1 | US FAERS | |
| 76 | Product packaging quantity issue | FAERS: 1 | US FAERS | |
| 77 | Purpura | FAERS: 1 | US FAERS | |
| 78 | Rash erythematous | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 79 | Restlessness | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 80 | Rosacea | FAERS: 1 | US FAERS | |
| 81 | Screaming | FAERS: 1 | OFFSIDES US FAERS | |
| 82 | Sepsis | FAERS: 1 | US FAERS | |
| 83 | Somnolence | FAERS: 1 | SIDER US FAERS | |
| 84 | Stevens-Johnson Syndrome | FAERS: 1 Canada Vigilance: 1 | 25811541 | CTD SIDER Canada Vigilance US FAERS |
| 85 | Stomatitis | FAERS: 1 | US FAERS | |
| 86 | Systemic Inflammatory Response Syndrome | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 87 | Tachycardia | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 88 | Tremor | FAERS: 1 | US FAERS | |
| 89 | Urine output increased | FAERS: 1 | OFFSIDES US FAERS | |
| 90 | Weight decreased | FAERS: 1 | US FAERS | |
| 91 | jaundice | FAERS: 1 | US FAERS | |
| 92 | Abdominal Pain | OFFSIDES SIDER | ||
| 93 | Abdominal tenderness | OFFSIDES | ||
| 94 | Abnormal vision | OFFSIDES | ||
| 95 | Acanthosis | Canada Vigilance: 2 | Canada Vigilance | |
| 96 | Accidental overdose | OFFSIDES | ||
| 97 | Acid reflux | OFFSIDES | ||
| 98 | Acidosis | OFFSIDES | ||
| 99 | Actinomycosis | OFFSIDES | ||
| 100 | Acute Lung Injury | Canada Vigilance: 2 | Canada Vigilance | |
| 101 | Acute prerenal failure | OFFSIDES | ||
| 102 | Acute sinusitis | OFFSIDES SIDER | ||
| 103 | Adenocarcinoma | OFFSIDES | ||
| 104 | Adenoma | OFFSIDES | ||
| 105 | Agitation | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 106 | Agranulocytosis | SIDER | ||
| 107 | Amnesia | OFFSIDES | ||
| 108 | Amphetamines | OFFSIDES | ||
| 109 | Anaphylactic shock | SIDER | ||
| 110 | Angioedema | SIDER | ||
| 111 | Anhedonia | OFFSIDES | ||
| 112 | Anhidrosis | OFFSIDES | ||
| 113 | Aortic valve sclerosis | OFFSIDES | ||
| 114 | Arteriosclerosis | OFFSIDES | ||
| 115 | Atelectasis | OFFSIDES | ||
| 116 | Atrial Flutter | OFFSIDES | ||
| 117 | Atrial tachycardia | OFFSIDES | ||
| 118 | Atrial thrombosis | OFFSIDES | ||
| 119 | Benign Prostatic Hyperplasia | OFFSIDES | ||
| 120 | Biliary Dyskinesia | OFFSIDES | ||
| 121 | Biopsy | OFFSIDES | ||
| 122 | Blood Glucose | OFFSIDES | ||
| 123 | Blood immunoglobulin M decreased | OFFSIDES | ||
| 124 | Blood lactate dehydrogenase increased | SIDER | ||
| 125 | Blood urea increased | OFFSIDES SIDER | ||
| 126 | Bone erosion | OFFSIDES | ||
| 127 | Bone fistula | OFFSIDES | ||
| 128 | Bone fragmentation | OFFSIDES | ||
| 129 | Bradycardia | OFFSIDES | ||
| 130 | Breast Cyst | OFFSIDES | ||
| 131 | Chemical and Drug Induced Liver Injury | 17366046 | CTD | |
| 132 | Choking sensation | OFFSIDES | ||
| 133 | Chondromalacia | OFFSIDES | ||
| 134 | Confabulation | OFFSIDES | ||
| 135 | Congenital diaphragmatic hernia | OFFSIDES | ||
| 136 | Congenital heart disease | OFFSIDES | ||
| 137 | Congenital tricuspid valve incompetence | OFFSIDES | ||
| 138 | Croup infectious | OFFSIDES | ||
| 139 | Cryptorchidism | OFFSIDES | ||
| 140 | Cystocele | OFFSIDES | ||
| 141 | Dacryostenosis acquired | OFFSIDES | ||
| 142 | Debridement | OFFSIDES | ||
| 143 | Demyelination | OFFSIDES | ||
| 144 | Dental Fistula | OFFSIDES | ||
| 145 | Dental abscess | OFFSIDES | ||
| 146 | Dermatitis | SIDER | ||
| 147 | Diabetic Retinopathy | OFFSIDES | ||
| 148 | Diarrhea | OFFSIDES | ||
| 149 | Disease recurrence | OFFSIDES | ||
| 150 | Diverticulitis | OFFSIDES | ||
| 151 | Drowsiness | SIDER | ||
| 152 | Drug exposure during pregnancy | OFFSIDES | ||
| 153 | Drug toxicity | OFFSIDES | ||
| 154 | Dry skin | Canada Vigilance: 1 | Canada Vigilance | |
| 155 | Duodenitis | OFFSIDES | ||
| 156 | Dysmenorrhea | OFFSIDES | ||
| 157 | Dyspepsia | OFFSIDES | ||
| 158 | Dysphonia | OFFSIDES | ||
| 159 | Ear congestion | OFFSIDES | ||
| 160 | Ecchymosis | Canada Vigilance: 1 | Canada Vigilance | |
| 161 | Eosinophilia | SIDER | ||
| 162 | Eosinophilic myocarditis | OFFSIDES | ||
| 163 | Erosive gastritis | OFFSIDES | ||
| 164 | Escherichia infection | OFFSIDES | ||
| 165 | Escherichia urinary tract infection | OFFSIDES | ||
| 166 | Excoriation | OFFSIDES | ||
| 167 | Exposure to toxic agent | OFFSIDES | ||
| 168 | Extremity necrosis | OFFSIDES | ||
| 169 | Fear of falling | OFFSIDES | ||
| 170 | Feeding disorder neonatal | OFFSIDES | ||
| 171 | Feeling Cold | OFFSIDES | ||
| 172 | Feeling abnormal | SIDER | ||
| 173 | Food aversion | OFFSIDES | ||
| 174 | Forceps delivery | OFFSIDES | ||
| 175 | Formication | OFFSIDES | ||
| 176 | Gastric ulcer | OFFSIDES | ||
| 177 | Gastrointestinal Pain | SIDER | ||
| 178 | Gastrointestinal inflammation | OFFSIDES | ||
| 179 | Globulinuria | OFFSIDES | ||
| 180 | Granuloma | OFFSIDES | ||
| 181 | Hepatitis C | OFFSIDES | ||
| 182 | Herpangina | OFFSIDES | ||
| 183 | Hyperkinesia | SIDER | ||
| 184 | Hypoaesthesia facial | OFFSIDES | ||
| 185 | Incoherent | OFFSIDES | ||
| 186 | Infection | OFFSIDES | ||
| 187 | Intentional drug misuse | OFFSIDES | ||
| 188 | Intestinal Obstruction | OFFSIDES | ||
| 189 | Intestinal Perforation | OFFSIDES | ||
| 190 | Intestinal resection | OFFSIDES | ||
| 191 | Joint sprain | OFFSIDES | ||
| 192 | Kidney Failure | OFFSIDES | ||
| 193 | Lactic dehydrogenase activity increased | SIDER | ||
| 194 | Left Ventricular Hypertrophy | OFFSIDES | ||
| 195 | Leukocytosis | Canada Vigilance: 2 | Canada Vigilance | |
| 196 | Loose tooth | OFFSIDES | ||
| 197 | Megacolon | OFFSIDES | ||
| 198 | Monoclonal immunoglobulin present | OFFSIDES | ||
| 199 | Multiple Myeloma | OFFSIDES | ||
| 200 | Neck Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 201 | Nervous tension | OFFSIDES | ||
| 202 | Nervousness | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 203 | Neutropenia | SIDER | ||
| 204 | Onychalgia | OFFSIDES | ||
| 205 | Osteolysis | OFFSIDES | ||
| 206 | Osteomyelitis | OFFSIDES | ||
| 207 | Pancreatitis | OFFSIDES | ||
| 208 | Pancytopenia | SIDER | ||
| 209 | Patellofemoral Pain Syndrome | OFFSIDES | ||
| 210 | Pericardial effusion | OFFSIDES | ||
| 211 | Pharyngeal lesion | OFFSIDES | ||
| 212 | Pharyngitis | SIDER | ||
| 213 | Phimosis | OFFSIDES | ||
| 214 | Poor peripheral circulation | OFFSIDES | ||
| 215 | Prescribed overdose | OFFSIDES | ||
| 216 | Pressure of speech | OFFSIDES | ||
| 217 | Psychomotor skills impaired | OFFSIDES | ||
| 218 | Pulmonary malformation | OFFSIDES | ||
| 219 | Purulent discharge | OFFSIDES | ||
| 220 | Red blood cell spherocytes present | OFFSIDES | ||
| 221 | Renal Artery Stenosis | OFFSIDES | ||
| 222 | Renal tubular necrosis | OFFSIDES | ||
| 223 | Respiratory Failure | OFFSIDES | ||
| 224 | Rhabdomyolysis | OFFSIDES | ||
| 225 | Seizures | 17111287 | CTD | |
| 226 | Septic Shock | OFFSIDES | ||
| 227 | Sick Sinus Syndrome | OFFSIDES | ||
| 228 | Sinusitis | OFFSIDES | ||
| 229 | Skin lesion | Canada Vigilance: 2 | Canada Vigilance | |
| 230 | Skin necrosis | OFFSIDES | ||
| 231 | Snoring | OFFSIDES | ||
| 232 | Stridor | OFFSIDES | ||
| 233 | Stupor | Canada Vigilance: 1 | Canada Vigilance | |
| 234 | Superinfection | SIDER | ||
| 235 | Tendinitis | OFFSIDES | ||
| 236 | Tension | SIDER | ||
| 237 | Thrombocytopenia | SIDER | ||
| 238 | Tongue erythema | Canada Vigilance: 2 | Canada Vigilance | |
| 239 | Tonsillitis | SIDER | ||
| 240 | Tooth Extraction | OFFSIDES | ||
| 241 | Tooth Infection | OFFSIDES | ||
| 242 | Transaminases increased | OFFSIDES | ||
| 243 | Transferrin decreased | OFFSIDES | ||
| 244 | Ulcer | OFFSIDES | ||
| 245 | Urine calcium increased | OFFSIDES | ||
| 246 | Ventricular hypokinesia | Canada Vigilance: 2 | Canada Vigilance | |
| 247 | Viral pharyngitis | OFFSIDES | ||
| 248 | Visual disturbance | OFFSIDES | ||
| 249 | Wound dehiscence | OFFSIDES | ||
| 250 | pseudomembranous colitis | SIDER |
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