propoxyphene napsylate
(VZPXFHVJUUSVLH-MYXGOWFTSA-N)
Structure
- SMILES
- OS(=O)(=O)c1ccc2c(c1)cccc2.CCC(=O)O[C@](c1ccccc1)([C@@H](CN(C)C)C)Cc1ccccc1
- Molecular Formula:
- C32H37NO5S
- Molecular Weight:
- 547.705
- Log P:
- 7.4428
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 1
- TPSA:
- 92.29
- CAS Number(s):
- 17140-78-2
Synonym(s)
1.
propoxyphene napsylate
2.
d-propoxyphene napsylate
3.
dextropropoxyphene napsylate
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Chest Pain | FAERS: 1 | US FAERS | |
| 2 | Dysuria | FAERS: 1 | US FAERS | |
| 3 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 4 | Pruritus | FAERS: 1 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 5 | Abdominal Pain | Canada Vigilance: 5 | Canada Vigilance OFFSIDES | |
| 6 | Abdominal discomfort | OFFSIDES | ||
| 7 | Accidental overdose | Canada Vigilance: 1 | Canada Vigilance | |
| 8 | Acidosis | OFFSIDES | ||
| 9 | Acne | Canada Vigilance: 1 | Canada Vigilance | |
| 10 | Acute respiratory failure | OFFSIDES | ||
| 11 | Adenitis | OFFSIDES | ||
| 12 | Adnexa uteri mass | OFFSIDES | ||
| 13 | Alcohol abuse | OFFSIDES | ||
| 14 | Amphetamines | OFFSIDES | ||
| 15 | Anhedonia | OFFSIDES | ||
| 16 | Anorexia | OFFSIDES | ||
| 17 | Anxiety | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 18 | Apathy | OFFSIDES | ||
| 19 | Arteriogram coronary abnormal | OFFSIDES | ||
| 20 | Asphyxia | Canada Vigilance: 1 | Canada Vigilance | |
| 21 | Asthenia | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 22 | Atelectasis | OFFSIDES | ||
| 23 | Bipolar Disorder | OFFSIDES | ||
| 24 | Blood alkaline phosphatase increased | Canada Vigilance: 1 | Canada Vigilance | |
| 25 | Blood cholesterol | OFFSIDES | ||
| 26 | Blood uric acid | OFFSIDES | ||
| 27 | Bone density decreased | OFFSIDES | ||
| 28 | Borderline Personality Disorder | OFFSIDES | ||
| 29 | Bowel movement irregularity | OFFSIDES | ||
| 30 | Bradycardia | OFFSIDES | ||
| 31 | Calcinosis | OFFSIDES | ||
| 32 | Cellulitis | OFFSIDES | ||
| 33 | Cerebellar infarction | OFFSIDES | ||
| 34 | Choking sensation | OFFSIDES | ||
| 35 | Cholecystitis infective | OFFSIDES | ||
| 36 | Chromaturia | Canada Vigilance: 1 | Canada Vigilance | |
| 37 | Chronic Obstructive Airway Disease | OFFSIDES | ||
| 38 | Chronic sinusitis | OFFSIDES | ||
| 39 | Completed Suicide | Canada Vigilance: 10 | Canada Vigilance | |
| 40 | Confabulation | OFFSIDES | ||
| 41 | Constipation | Canada Vigilance: 4 | Canada Vigilance | |
| 42 | Contact Dermatitis | OFFSIDES | ||
| 43 | Conversion disorder | Canada Vigilance: 1 | Canada Vigilance | |
| 44 | Dehydration | OFFSIDES | ||
| 45 | Demyelination | OFFSIDES | ||
| 46 | Denture wearer | OFFSIDES | ||
| 47 | Dependence | OFFSIDES | ||
| 48 | Dependent Personality Disorder | OFFSIDES | ||
| 49 | Dermatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 50 | Diarrhea | OFFSIDES | ||
| 51 | Diplopia | Canada Vigilance: 2 | Canada Vigilance OFFSIDES | |
| 52 | Disorientation | Canada Vigilance: 1 | Canada Vigilance | |
| 53 | Diverticulum | OFFSIDES | ||
| 54 | Dizziness | Canada Vigilance: 10 | Canada Vigilance | |
| 55 | Drug withdrawal convulsions | Canada Vigilance: 1 | Canada Vigilance | |
| 56 | Dysmenorrhea | OFFSIDES | ||
| 57 | Dyspepsia | Canada Vigilance: 1 | Canada Vigilance | |
| 58 | Dysphonia | OFFSIDES | ||
| 59 | Economic problem | OFFSIDES | ||
| 60 | Eczema | OFFSIDES | ||
| 61 | Embolic stroke | OFFSIDES | ||
| 62 | Embolism | OFFSIDES | ||
| 63 | Emotional distress | OFFSIDES | ||
| 64 | Endocarditis | OFFSIDES | ||
| 65 | Epistaxis | Canada Vigilance: 1 | Canada Vigilance | |
| 66 | Erythema Multiforme | Canada Vigilance: 1 | Canada Vigilance | |
| 67 | Erythema | Canada Vigilance: 3 | Canada Vigilance | |
| 68 | Eustachian tube disorder | OFFSIDES | ||
| 69 | Eye pain | OFFSIDES | ||
| 70 | Face Lift | OFFSIDES | ||
| 71 | Fatty Liver | OFFSIDES | ||
| 72 | Fixed eruption | Canada Vigilance: 1 | Canada Vigilance | |
| 73 | Gastritis | Canada Vigilance: 1 | Canada Vigilance | |
| 74 | Gingival Hyperplasia | OFFSIDES | ||
| 75 | Glossitis | Canada Vigilance: 1 | Canada Vigilance | |
| 76 | Goiter | OFFSIDES | ||
| 77 | Headache | Canada Vigilance: 3 | Canada Vigilance | |
| 78 | Hepatitis | Canada Vigilance: 3 | Canada Vigilance | |
| 79 | Hypophagia | OFFSIDES | ||
| 80 | Ileal ulcer | OFFSIDES | ||
| 81 | Impetigo | OFFSIDES | ||
| 82 | Inflammation | Canada Vigilance: 1 | Canada Vigilance | |
| 83 | Intellectual Disability | Canada Vigilance: 1 | Canada Vigilance | |
| 84 | Intention tremor | OFFSIDES | ||
| 85 | Joint injury | OFFSIDES | ||
| 86 | Keratitis sicca | OFFSIDES | ||
| 87 | Kidney Failure | OFFSIDES | ||
| 88 | Kidney Papillary Necrosis | 6126946 | CTD | |
| 89 | Life expectancy shortened | OFFSIDES | ||
| 90 | Malaise | Canada Vigilance: 2 | Canada Vigilance | |
| 91 | Medical device removal | OFFSIDES | ||
| 92 | Medication Error | Canada Vigilance: 1 | Canada Vigilance | |
| 93 | Metabolic acidosis | OFFSIDES | ||
| 94 | Multiple Myeloma | OFFSIDES | ||
| 95 | Multiple drug overdose | OFFSIDES | ||
| 96 | Musculoskeletal Pain | OFFSIDES | ||
| 97 | Nail Infection | OFFSIDES | ||
| 98 | Nausea | Canada Vigilance: 10 | Canada Vigilance OFFSIDES | |
| 99 | Nephrocalcinosis | 6126946 | CTD | |
| 100 | Nephrolithiasis | OFFSIDES | ||
| 101 | Nodule | OFFSIDES | ||
| 102 | Oropharyngeal pain | OFFSIDES | ||
| 103 | Oropharyngeal plaque | OFFSIDES | ||
| 104 | Osteolysis | OFFSIDES | ||
| 105 | Osteomyelitis | OFFSIDES | ||
| 106 | Osteopenia | OFFSIDES | ||
| 107 | Pain | OFFSIDES | ||
| 108 | Pallor | Canada Vigilance: 1 | Canada Vigilance | |
| 109 | Palpitations | Canada Vigilance: 1 | Canada Vigilance | |
| 110 | Pancreatitis | OFFSIDES | ||
| 111 | Parotitis | OFFSIDES | ||
| 112 | Physical disability | OFFSIDES | ||
| 113 | Pneumothorax | OFFSIDES | ||
| 114 | Pulmonary Hypertension | OFFSIDES | ||
| 115 | Rash erythematous | Canada Vigilance: 2 | Canada Vigilance | |
| 116 | Renal tubular necrosis | OFFSIDES | ||
| 117 | Respiratory Failure | OFFSIDES | ||
| 118 | Restrictive pulmonary disease | OFFSIDES | ||
| 119 | Retinal Vasculitis | OFFSIDES | ||
| 120 | Rhinitis | Canada Vigilance: 1 | Canada Vigilance | |
| 121 | Sarcoidosis | OFFSIDES | ||
| 122 | Septic Shock | OFFSIDES | ||
| 123 | Sinusitis | OFFSIDES | ||
| 124 | Sjogren's Syndrome | OFFSIDES | ||
| 125 | Somnolence | Canada Vigilance: 1 | Canada Vigilance | |
| 126 | Synovial Cyst | OFFSIDES | ||
| 127 | Thermal burn | Canada Vigilance: 1 | Canada Vigilance | |
| 128 | Tinnitus | Canada Vigilance: 2 | Canada Vigilance | |
| 129 | Tooth Extraction | OFFSIDES | ||
| 130 | Unresponsive to stimuli | OFFSIDES | ||
| 131 | Urticaria | Canada Vigilance: 9 | Canada Vigilance | |
| 132 | Uterine Polyp | OFFSIDES | ||
| 133 | Vertigo | Canada Vigilance: 2 | Canada Vigilance | |
| 134 | Visual Impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 135 | Vomiting | Canada Vigilance: 8 | Canada Vigilance | |
| 136 | Wound dehiscence | OFFSIDES | ||
| 137 | jaundice | Canada Vigilance: 1 | Canada Vigilance |
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