MetaADEDB 2.0 @ LMMD
Melphalan
(SGDBTWWWUNNDEQ-LBPRGKRZSA-N)
Structure
SMILES
ClCCN(c1ccc(cc1)C[C@@H](C(=O)O)N)CCCl
Type(s)
Approved
ATC code(s)
L01AA03
Molecular Formula:
C13H18Cl2N2O2
Molecular Weight:
305.200
Log P:
2.6253
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
66.56
CAS Number(s):
148-82-3; 8057-25-8
Synonym(s)
1.
Melphalan
2.
Medphalan
3.
Merphalan
4.
Phenylalanine Mustard
5.
Sarcolysine
6.
Sarkolysin
7.
4-(Bis(2-chloroethyl)amino)phenylalanine
8.
Alkeran
9.
L-PAM
10.
Mustard, Phenylalanine
External Link(s)
MeSHD008558
PubChem Compound460612
6918992
BindingDB50025837
ChEBI28876
CHEMBLCHEMBL852
DrugBankDB01042
DrugCentral1678
IUPHAR/BPS Guide to PHARMACOLOGY7620
KEGGcpd:C07122
dr:D00369
Therapeutic Target DatabaseD00FGO
ZINC1673
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Febrile NeutropeniaFAERS: 41OFFSIDES
SIDER
US FAERS
2Chorioretinal atrophyFAERS: 35US FAERS
3NauseaFAERS: 24

View details

2849690
8759893
10379864
10656432
 		CTD
OFFSIDES
SIDER
US FAERS
4VomitingFAERS: 248759893
10656432
10971385		CTD
SIDER
US FAERS
5NeutropeniaFAERS: 19

View details

9676843
10656432
11846301
18463870
 		CTD
SIDER
US FAERS
6SepsisFAERS: 193597002
10656432		CTD
US FAERS
7PancytopeniaFAERS: 18
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
8PneumoniaFAERS: 17US FAERS
9ThrombocytopeniaFAERS: 17
Canada Vigilance: 1

View details

1730428
7060036
10656432
11846301
18463870
 		CTD
SIDER
Canada Vigilance
US FAERS
10Atrial FibrillationFAERS: 169632280
9676843
10373065		CTD
SIDER
US FAERS
11HypotensionFAERS: 1310379864CTD
SIDER
US FAERS
12Stem cell transplantFAERS: 13OFFSIDES
US FAERS
13CataractFAERS: 12OFFSIDES
US FAERS
14Retinal DetachmentFAERS: 12US FAERS
15Retinogram abnormalFAERS: 12US FAERS
16Ocular ToxicityFAERS: 11US FAERS
17Retinal VasculitisFAERS: 10US FAERS
18White blood cell count decreasedFAERS: 9US FAERS
19FatigueFAERS: 88759893CTD
OFFSIDES
SIDER
US FAERS
20Retinal pigment epitheliopathyFAERS: 8US FAERS
21DehydrationFAERS: 7OFFSIDES
US FAERS
22Hepatitis BFAERS: 7US FAERS
23Retinal Artery OcclusionFAERS: 7US FAERS
24Septic ShockFAERS: 7OFFSIDES
US FAERS
25StomatitisFAERS: 7SIDER
US FAERS
26Abdominal PainFAERS: 6OFFSIDES
US FAERS
27Back PainFAERS: 6US FAERS
28DizzinessFAERS: 6US FAERS
29Gastrointestinal toxicityFAERS: 6US FAERS
30HeadacheFAERS: 6US FAERS
31Respiratory FailureFAERS: 6OFFSIDES
US FAERS
32Retinal DegenerationFAERS: 6US FAERS
33Toxicity to various agentsFAERS: 6US FAERS
34Adverse eventFAERS: 5US FAERS
35AgranulocytosisFAERS: 51730428CTD
US FAERS
36AnorexiaFAERS: 58759893CTD
OFFSIDES
SIDER
US FAERS
37AstheniaFAERS: 5OFFSIDES
SIDER
US FAERS
38AsthmaFAERS: 5US FAERS
39Blood creatinine increasedFAERS: 5US FAERS
40Failure to ThriveFAERS: 5US FAERS
41HypoxiaFAERS: 5OFFSIDES
US FAERS
42InfectionFAERS: 57802575CTD
OFFSIDES
SIDER
US FAERS
43Neutrophil count decreasedFAERS: 5US FAERS
44Optic AtrophyFAERS: 5US FAERS
45OverdoseFAERS: 5US FAERS
46Pulmonary FibrosisFAERS: 52849690
21129433
22776411		CTD
SIDER
US FAERS
47ArthralgiaFAERS: 4US FAERS
48Depressed Level of ConsciousnessFAERS: 4US FAERS
49Drug administration errorFAERS: 4US FAERS
50ErythemaFAERS: 4OFFSIDES
US FAERS
51General physical health deteriorationFAERS: 4OFFSIDES
US FAERS
52Multiple MyelomaFAERS: 4

View details

183029
194338
206105
1803051
1806033
2372790
3039073
3597002
3838922
7060036
7534716
7894029
9304704
9436936
10373065
10459345
10578165
10618687
10713631
10955873
12368962
12481892
12791655
15193449
16019253
16506632
16611307
16860177
17355553
17895401
18463870
18726593
19101782
19259673
19602793
20038224
20807892
20864405
20874823
 		CTD
OFFSIDES
US FAERS
53Neuralgic AmyotrophyFAERS: 4US FAERS
54Productive CoughFAERS: 4OFFSIDES
US FAERS
55Retinal depigmentationFAERS: 4US FAERS
56Retinal toxicityFAERS: 4US FAERS
57RhabdomyosarcomaFAERS: 48062269
11846301		CTD
US FAERS
58StrongyloidiasisFAERS: 4US FAERS
59SyncopeFAERS: 4US FAERS
60TremorFAERS: 4US FAERS
61Urinary tract infectionFAERS: 4US FAERS
62Vascular occlusionFAERS: 4US FAERS
63Weight decreasedFAERS: 4US FAERS
64Acute respiratory failureFAERS: 3US FAERS
65AmputationFAERS: 3OFFSIDES
US FAERS
66AtelectasisFAERS: 3OFFSIDES
US FAERS
67Blood amylase increasedFAERS: 3US FAERS
68Bone SarcomaFAERS: 3OFFSIDES
US FAERS
69Cardiac ArrestFAERS: 3SIDER
US FAERS
70Disease ProgressionFAERS: 3OFFSIDES
US FAERS
71Drug prescribing errorFAERS: 3US FAERS
72Hilar lymphadenopathyFAERS: 3US FAERS
73Idiopathic pneumonia syndromeFAERS: 3US FAERS
74LeukopeniaFAERS: 33597002
7060036		CTD
SIDER
US FAERS
75ShockFAERS: 3US FAERS
76Soft tissue massFAERS: 3US FAERS
77SomnolenceFAERS: 3US FAERS
78Venoocclusive diseaseFAERS: 3OFFSIDES
SIDER
US FAERS
79effusionFAERS: 3US FAERS
80Accidental exposureFAERS: 2US FAERS
81Alanine Aminotransferase IncreasedFAERS: 2US FAERS
82AlopeciaFAERS: 2OFFSIDES
SIDER
US FAERS
83Anaplastic large cell lymphoma T- and null-cell typesFAERS: 2US FAERS
84Angina PectorisFAERS: 2US FAERS
85Ankle FractureFAERS: 2OFFSIDES
US FAERS
86AscitesFAERS: 2US FAERS
87Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
88AsphyxiaFAERS: 2US FAERS
89AzoospermiaFAERS: 2US FAERS
90BronchitisFAERS: 2OFFSIDES
US FAERS
91CardiomegalyFAERS: 2US FAERS
92Central line infectionFAERS: 2US FAERS
93Cerebral InfarctionFAERS: 2US FAERS
94Chest PainFAERS: 2SIDER
US FAERS
95ChillsFAERS: 28759893CTD
US FAERS
96Clostridium colitisFAERS: 2US FAERS
97Clostridium difficile colitisFAERS: 2US FAERS
98Cytokine stormFAERS: 2US FAERS
99Deep Vein ThrombosisFAERS: 2US FAERS
100Drug dispensing errorFAERS: 2US FAERS
101Drug ineffectiveFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
102DyspepsiaFAERS: 2SIDER
US FAERS
103DysuriaFAERS: 2OFFSIDES
US FAERS
104Enterococcal infectionFAERS: 2US FAERS
105EpilepsyFAERS: 2US FAERS
106EpistaxisFAERS: 2US FAERS
107Hospice CareFAERS: 2US FAERS
108HyperferritinaemiaFAERS: 2US FAERS
109HypersensitivityFAERS: 2SIDER
US FAERS
110IleusFAERS: 2US FAERS
111InfluenzaFAERS: 2US FAERS
112Intervertebral disc disorderFAERS: 2OFFSIDES
US FAERS
113MYELODYSPLASTIC SYNDROMEFAERS: 2US FAERS
114MalaiseFAERS: 2US FAERS
115Mental status changesFAERS: 2OFFSIDES
US FAERS
116NecrosisFAERS: 2US FAERS
117Neutropenic sepsisFAERS: 2US FAERS
118PainFAERS: 27802575
8759893		CTD
OFFSIDES
SIDER
US FAERS
119PancreatitisFAERS: 2US FAERS
120ParotitisFAERS: 2OFFSIDES
US FAERS
121PetechiaeFAERS: 2US FAERS
122Post procedural complicationFAERS: 2US FAERS
123Primary hypogonadismFAERS: 2US FAERS
124Product depositFAERS: 2US FAERS
125Product substitution issueFAERS: 2US FAERS
126PruritusFAERS: 2SIDER
US FAERS
127Renal tubular disorderFAERS: 2OFFSIDES
US FAERS
128Respiratory arrestFAERS: 2US FAERS
129Respiratory distressFAERS: 2SIDER
US FAERS
130Septic embolusFAERS: 2US FAERS
131Skin lesionFAERS: 2OFFSIDES
US FAERS
132TachycardiaFAERS: 210379864CTD
SIDER
US FAERS
133ThrombosisFAERS: 2US FAERS
134Transaminases increasedFAERS: 2SIDER
US FAERS
135Varicella Zoster Virus InfectionFAERS: 2US FAERS
136Vascular calcificationFAERS: 2US FAERS
137Ventricular arrhythmiaFAERS: 2US FAERS
138Acute kidney injuryFAERS: 12849690
15696449		CTD
US FAERS
139Acute myocardial infarctionFAERS: 1US FAERS
140AmnesiaFAERS: 1OFFSIDES
US FAERS
141AmyloidosisFAERS: 110578165
17130952
18641023		CTD
US FAERS
142AnuriaFAERS: 1US FAERS
143ApathyFAERS: 1US FAERS
144AphasiaFAERS: 1US FAERS
145ArthritisFAERS: 1OFFSIDES
US FAERS
146Bacterial sepsisFAERS: 1OFFSIDES
US FAERS
147Blast cells presentFAERS: 1US FAERS
148BlindnessFAERS: 1US FAERS
149Blood glucose increasedFAERS: 1US FAERS
150Blood sodium decreasedFAERS: 1US FAERS
151Blood urea increasedFAERS: 1US FAERS
152BradycardiaFAERS: 1US FAERS
153BronchiolitisFAERS: 1US FAERS
154BronchopneumoniaFAERS: 1US FAERS
155Bronchopulmonary AspergillosisFAERS: 1US FAERS
156Bronchoscopy abnormalFAERS: 1US FAERS
157CandidiasisFAERS: 1US FAERS
158Cardiac TamponadeFAERS: 1US FAERS
159CardiotoxicityFAERS: 1US FAERS
160Cardiovascular insufficiencyFAERS: 1US FAERS
161Catheter related infectionFAERS: 1US FAERS
162Catheter site cellulitisFAERS: 1US FAERS
163Cerebrovascular accidentFAERS: 1US FAERS
164Cervical cord compressionFAERS: 1US FAERS
165ChokingFAERS: 1US FAERS
166CholelithiasisFAERS: 1US FAERS
167Clostridium difficile infectionFAERS: 1US FAERS
168Colitis erosiveFAERS: 1US FAERS
169ColitisFAERS: 1US FAERS
170Conjunctival blebFAERS: 1US FAERS
171Conjunctival ulcerFAERS: 1US FAERS
172Coombs test negativeFAERS: 1US FAERS
173Corynebacterium sepsisFAERS: 1US FAERS
174CyanosisFAERS: 1US FAERS
175CystitisFAERS: 1SIDER
US FAERS
176Cytomegalovirus antigen positiveFAERS: 1US FAERS
177Cytomegalovirus testFAERS: 1US FAERS
178CytopeniaFAERS: 1US FAERS
179DeafnessFAERS: 1US FAERS
180DementiaFAERS: 1US FAERS
181Device related infectionFAERS: 1US FAERS
182Diffuse Large B-Cell LymphomaFAERS: 1US FAERS
183DiplopiaFAERS: 1OFFSIDES
US FAERS
184DiverticulumFAERS: 1OFFSIDES
US FAERS
185Drug toxicityFAERS: 1OFFSIDES
US FAERS
186DuodenitisFAERS: 1US FAERS
187DwarfismFAERS: 1US FAERS
188DysarthriaFAERS: 1US FAERS
189Emergency care examinationFAERS: 1US FAERS
190Empty Sella SyndromeFAERS: 1US FAERS
191EmpyemaFAERS: 1US FAERS
192EnteritisFAERS: 1US FAERS
193EnterocolitisFAERS: 1OFFSIDES
US FAERS
194Enterovirus test positiveFAERS: 1US FAERS
195EosinophiliaFAERS: 1US FAERS
196EructationFAERS: 1US FAERS
197Erythema MultiformeFAERS: 1US FAERS
198ExophthalmosFAERS: 1US FAERS
199Extra dose administeredFAERS: 1US FAERS
200Eye excisionFAERS: 1US FAERS
201FibromyalgiaFAERS: 1US FAERS
202FibrosarcomaFAERS: 1US FAERS
203Fluid intake restrictionFAERS: 1US FAERS
204Fluid overloadFAERS: 1OFFSIDES
US FAERS
205GastritisFAERS: 1US FAERS
206GlaucomaFAERS: 1US FAERS
207GoutFAERS: 1US FAERS
208Haptoglobin DecreasedFAERS: 1OFFSIDES
US FAERS
209HemiplegiaFAERS: 1US FAERS
210HepatitisFAERS: 1SIDER
US FAERS
211HepatotoxicityFAERS: 1OFFSIDES
US FAERS
212Human rhinovirus test positiveFAERS: 1US FAERS
213HyperinsulinismFAERS: 1US FAERS
214HypersomniaFAERS: 1US FAERS
215HypothyroidismFAERS: 1US FAERS
216Impaired gastric emptyingFAERS: 1US FAERS
217Incorrect dose administeredFAERS: 1US FAERS
218Incorrect product storageFAERS: 1US FAERS
219Incorrect storage of drugFAERS: 1US FAERS
220Injection site joint inflammationFAERS: 1US FAERS
221Injection site painFAERS: 1US FAERS
222Irritable Bowel SyndromeFAERS: 1US FAERS
223KeratopathyFAERS: 1US FAERS
224LethargyFAERS: 1US FAERS
225LeukoencephalopathyFAERS: 1OFFSIDES
US FAERS
226Lobar PneumoniaFAERS: 1US FAERS
227Lyme DiseaseFAERS: 1US FAERS
228Lymphocytic infiltrationFAERS: 1OFFSIDES
US FAERS
229Lymphomatoid PapulosisFAERS: 1US FAERS
230LymphomaFAERS: 1SIDER
US FAERS
231Malignant transformationFAERS: 1US FAERS
232Medication ErrorFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
233Musculoskeletal PainFAERS: 1US FAERS
234Myocardial InfarctionFAERS: 13597002CTD
US FAERS
235Myoclonic EpilepsyFAERS: 1US FAERS
236MyoclonusFAERS: 1US FAERS
237MyopathyFAERS: 1US FAERS
238Ocular vascular disorderFAERS: 1US FAERS
239OliguriaFAERS: 1US FAERS
240OtotoxicityFAERS: 1US FAERS
241Ovarian failureFAERS: 1US FAERS
242PachymeningitisFAERS: 1US FAERS
243PallorFAERS: 1US FAERS
244Pancreatic enzymes increasedFAERS: 1US FAERS
245Pericardial effusionFAERS: 1US FAERS
246PericarditisFAERS: 1US FAERS
247Peripheral embolismFAERS: 1US FAERS
248Personality ChangeFAERS: 1OFFSIDES
US FAERS
249Pharmaceutical product complaintFAERS: 1US FAERS
250PhotophobiaFAERS: 1US FAERS
251PityriasisFAERS: 1US FAERS
252Platelet TransfusionFAERS: 1OFFSIDES
US FAERS
253Pneumocystis jiroveci pneumoniaFAERS: 1US FAERS
254PneumonitisFAERS: 1US FAERS
255PneumothoraxFAERS: 1OFFSIDES
US FAERS
256Posterior reversible encephalopathy syndromeFAERS: 1US FAERS
257Primary HypothyroidismFAERS: 1US FAERS
258Procedural complicationFAERS: 1US FAERS
259Product quality issueFAERS: 1US FAERS
260Protein total increasedFAERS: 1OFFSIDES
US FAERS
261Pseudomonas test positiveFAERS: 1US FAERS
262Pulmonary HypertensionFAERS: 1US FAERS
263Pulmonary function test decreasedFAERS: 1US FAERS
264Pulmonary thrombosisFAERS: 1US FAERS
265Pulmonary toxicityFAERS: 1SIDER
US FAERS
266Punctate keratitisFAERS: 1US FAERS
267Refractory cytopenia with multilineage dysplasiaFAERS: 1US FAERS
268Respiratory syncytial virus test positiveFAERS: 1US FAERS
269Respiratory tract congestionFAERS: 1US FAERS
270Retinal Vascular DisorderFAERS: 1US FAERS
271Retinal infarctionFAERS: 1OFFSIDES
US FAERS
272Retinal infiltratesFAERS: 1US FAERS
273Retinal pigmentationFAERS: 1US FAERS
274RhabdomyolysisFAERS: 1SIDER
US FAERS
275Salivary gland painFAERS: 1US FAERS
276StrabismusFAERS: 1US FAERS
277SwellingFAERS: 1US FAERS
278Systemic Inflammatory Response SyndromeFAERS: 1US FAERS
279Thoracic vertebral fractureFAERS: 1US FAERS
280Toxic Epidermal NecrolysisFAERS: 1US FAERS
281Toxic anterior segment syndromeFAERS: 1US FAERS
282Trigeminal Nerve DisorderFAERS: 1US FAERS
283Unevaluable eventFAERS: 1US FAERS
284Unresponsive to stimuliFAERS: 1OFFSIDES
US FAERS
285VertigoFAERS: 1US FAERS
286Visual disturbanceFAERS: 1US FAERS
287Walking aid userFAERS: 1OFFSIDES
US FAERS
288treatment failureFAERS: 1US FAERS
289Abdominal discomfortOFFSIDES
290Abdominal symptomOFFSIDES
291Abdominal tendernessOFFSIDES
292Abnormal visionOFFSIDES
293AbscessOFFSIDES
294AbuseOFFSIDES
295Accidental overdoseCanada Vigilance: 2Canada Vigilance
296Acid refluxOFFSIDES
297ActinomycosisOFFSIDES
298Activities of daily living impairedOFFSIDES
299Acute graft versus host disease in intestineOFFSIDES
300Acute graft versus host disease in liverOFFSIDES
301Acute sinusitisOFFSIDES
302Adenocarcinoma10656432CTD
303AgeusiaOFFSIDES
304AlkalosisOFFSIDES
305AlveoloplastyOFFSIDES
306AmphetaminesOFFSIDES
307Anaphylactic shockSIDER
308Anemia11846301
18463870		CTD
309Aneuploidy22025197CTD
310AnhedoniaOFFSIDES
311AnhidrosisOFFSIDES
312AnxietyOFFSIDES
313Aortic AneurysmOFFSIDES
314ApoptosisOFFSIDES
315Arachnoiditis8043096CTD
316Arterial thrombosisSIDER
317ArthropathyOFFSIDES
318AspergillosisOFFSIDES
319AtaxiaOFFSIDES
320Atrial tachycardiaOFFSIDES
321AuraOFFSIDES
322Back disorderOFFSIDES
323Bacterial test positiveOFFSIDES
324Beta 2 microglobulin decreasedOFFSIDES
325Beta 2 microglobulin increasedOFFSIDES
326Bile Duct Diseases12606622CTD
327Biopsy bone abnormalOFFSIDES
328Biopsy site unspecified abnormalOFFSIDES
329BiopsyOFFSIDES
330Bladder painSIDER
331Bladder prolapseOFFSIDES
332BlepharitisOFFSIDES
333Blood GlucoseOFFSIDES
334Blood and lymphatic system disordersSIDER
335Blood bilirubin unconjugated increasedOFFSIDES
336Blood cholesterolOFFSIDES
337Blood creatine phosphokinase increasedOFFSIDES
SIDER
338Blood fibrinogenOFFSIDES
339Blood immunoglobulin A increasedOFFSIDES
340Blood immunoglobulin G increasedOFFSIDES
341Blood lactate dehydrogenase increasedOFFSIDES
342Blood potassium decreasedOFFSIDES
343Blood product transfusion dependentOFFSIDES
344Blood sodium increasedOFFSIDES
345Blood uric acid decreasedOFFSIDES
346Bone Marrow Diseases2849690CTD
347Bone density decreasedOFFSIDES
348Bone erosionOFFSIDES
349Bone fissureOFFSIDES
350Bone fragmentationOFFSIDES
351Bone lesionOFFSIDES
352Bone marrow depressionSIDER
353Bone painOFFSIDES
354Bone swellingOFFSIDES
355Bone trimmingOFFSIDES
356Brain natriuretic peptide increasedOFFSIDES
357Bronchial Hyperreactivity22776411CTD
358Bronchoalveolar LavageOFFSIDES
359BronchospasmSIDER
360BruxismOFFSIDES
361BunionOFFSIDES
362Burkitt Lymphoma3965085CTD
363Burning Mouth SyndromeOFFSIDES
364Burning sensationOFFSIDES
365BursitisOFFSIDES
366CYTOMEGALOVIRUS ANTIGENOFFSIDES
367Candida sepsisOFFSIDES
368Carcinoma9404925CTD
369Cardiac asthmaOFFSIDES
370Cardiomyopathies6940649CTD
371Cataract operationOFFSIDES
372Catatonia2742733CTD
373CellulitisOFFSIDES
374Cerebral Hemorrhage9404925CTD
375Charles Bonnet SyndromeOFFSIDES
376Chemical and Drug Induced Liver Injury9676843
14595385		CTD
377Choking sensationOFFSIDES
378Circumstance or information capable of leading to medication errorCanada Vigilance: 1Canada Vigilance
379Coagulation test abnormalOFFSIDES
380ColectomyOFFSIDES
381Colon adenomaOFFSIDES
382Complications of bone marrow transplantOFFSIDES
383Compression fractureOFFSIDES
384Compression stockings applicationOFFSIDES
385Cord blood transplant therapyOFFSIDES
386Coronary angioplastyOFFSIDES
387Culture wound positiveOFFSIDES
388Cutaneous hypersensitivitySIDER
389CystOFFSIDES
390Cytomegalovirus gastroenteritisOFFSIDES
391Deafness NeurosensoryOFFSIDES
392DebridementOFFSIDES
393Demyelinating Diseases8043096CTD
394DemyelinationOFFSIDES
395Dental FistulaOFFSIDES
396Dental abscessOFFSIDES
397Dental cariesOFFSIDES
398Denture wearerOFFSIDES
399DermatitisSIDER
400Device breakageOFFSIDES
401Device malfunctionOFFSIDES
402Diarrhea3153241
10971385		CTD
OFFSIDES
403Drug screen positiveOFFSIDES
404Drug withdrawal headacheOFFSIDES
405DysphoniaOFFSIDES
406Early satietyOFFSIDES
407EczemaOFFSIDES
408Ejection Fraction DecreasedOFFSIDES
409Emotional distressOFFSIDES
410Endodontic procedureOFFSIDES
411Endotracheal intubation complicationOFFSIDES
412Engraft failureOFFSIDES
413Engraftment syndromeOFFSIDES
414Enterocutaneous FistulaOFFSIDES
415Epstein-Barr virus associated lymphoproliferative disorderOFFSIDES
416Esophageal Stenosis9404925CTD
417Eustachian tube disorderOFFSIDES
418ExcoriationOFFSIDES
419Exploratory operationOFFSIDES
420ExtravasationSIDER
421FasciotomyOFFSIDES
422Fever

View details

8759893
9436936
9676843
10379864
 		CTD
423Fibromatosis, Aggressive19944662CTD
424Fibrosis7802575CTD
425Fistula repairOFFSIDES
426FlushingSIDER
427Gastrointestinal Diseases6403413
10955873		CTD
428Gastrointestinal arteriovenous malformationOFFSIDES
429Gastrointestinal motility disorderOFFSIDES
430Gingival HypertrophyOFFSIDES
431Gingival graftOFFSIDES
432Glioblastoma18584351CTD
433Glioma8062269CTD
434Grip strengthOFFSIDES
435HaematotoxicityCanada Vigilance: 6Canada Vigilance
OFFSIDES
436Hematemesis9404925CTD
437Hepaplastin decreasedOFFSIDES
438Hepatic Veno-Occlusive Disease

View details

2314142
10534061
14595385
18022574
19767780
 		CTD
439Hepatitis C RNAOFFSIDES
440Hepatitis C antibody positiveOFFSIDES
441HepatosplenomegalyOFFSIDES
442Hip surgeryOFFSIDES
443Histiocytosis haematophagicOFFSIDES
444HistologyOFFSIDES
445Hodgkin Disease10955873CTD
446Hyperbilirubinemia10379864CTD
447HyperkeratosisOFFSIDES
448HyperkinesiaCanada Vigilance: 1Canada Vigilance
449Hypoaesthesia facialOFFSIDES
450Hyponatremia3153241
3965085		CTD
451HypophagiaOFFSIDES
452Immunodeficiency congenitalOFFSIDES
453ImmunosuppressionOFFSIDES
454InfertilitySIDER
455Injection Site ReactionSIDER
456Intervertebral Disc DegenerationOFFSIDES
457Intracranial AneurysmOFFSIDES
458IntubationOFFSIDES
459Keratitis siccaOFFSIDES
460Kidney Diseases10955873CTD
461Kidney Failure, Chronic4571885CTD
462Kidney FailureOFFSIDES
463Klebsiella sepsisOFFSIDES
464Left Ventricular HypertrophyOFFSIDES
465Leukemia, Plasma Cell4571885
9404934		CTD
466Leukopenia neonatalOFFSIDES
467Life expectancy shortenedOFFSIDES
468Liver diseases10955873
12606622		CTD
469Liver neoplasms12606622CTD
470Local reactionSIDER
471Locked-In SyndromeOFFSIDES
472Loose toothOFFSIDES
473Lumbar radiculopathyOFFSIDES
474Lung Diseases, Interstitial9404925CTD
475Lung infection pseudomonalOFFSIDES
476Lymphedema7802575CTD
477Lymphocyte count decreasedOFFSIDES
478Lymphoma, Non-Hodgkin10955873
19767780		CTD
479MacroglossiaOFFSIDES
480Malignant neoplasm progressionOFFSIDES
481Mastication disorderOFFSIDES
482Mechanical ventilationOFFSIDES
483Medulloblastoma8043096CTD
484Melanoma, Experimental24287558CTD
485Meningeal Carcinomatosis8043096
8062269		CTD
486MetaplasiaOFFSIDES
487Micronuclei, Chromosome-Defective22025197
22923490		CTD
488Microsporum infectionOFFSIDES
489Mitral Valve Insufficiency18548196CTD
490Monoclonal immunoglobulin presentOFFSIDES
491MononeuritisOFFSIDES
492Mouth plaqueOFFSIDES
493Multi-centric Castleman's Disease17915620CTD
494Muscle WeaknessOFFSIDES
495Muscle damageSIDER
496Muscle fibrosisSIDER
497Muscle necrosisSIDER
498Muscle strainOFFSIDES
499Muscular Atrophy7802575CTD
500Musculoskeletal chest painOFFSIDES
501Musculoskeletal discomfortOFFSIDES
SIDER
502MyalgiaSIDER
503MyelosuppressionSIDER
504Nail Diseases2849690CTD
505Neoplasm Metastasis9676843CTD
506Neoplasms, Unknown Primary10656432CTD
507Neoplasms8971371CTD
508NeuralgiaOFFSIDES
509Neuroblastoma2327660
14595385
18353067		CTD
510NeuropathySIDER
511Neutropenic infectionOFFSIDES
512Neutrophil Chemotactic Response, Abnormal22776411CTD
513Neutrophil count abnormalOFFSIDES
514Nodular regenerative hyperplasiaOFFSIDES
515Nodule on extremityOFFSIDES
516Nuclear magnetic resonance imaging brainOFFSIDES
517Ocular HypertensionOFFSIDES
518Open reduction of fractureOFFSIDES
519Optic NeuritisOFFSIDES
520Oral Cavity FistulaOFFSIDES
521Oral infectionOFFSIDES
522Oral mucosa atrophyOFFSIDES
523OrchitisOFFSIDES
524Oropharyngeal painOFFSIDES
525OsteolysisOFFSIDES
526OsteomyelitisOFFSIDES
527OsteopeniaOFFSIDES
528OsteoporosisOFFSIDES
529Osteosarcoma6940649CTD
530Osteosclerosis3039073CTD
OFFSIDES
531Pain managementOFFSIDES
532PeriodontitisOFFSIDES
533Peripheral Nervous System Diseases20807892
20874823		CTD
534Peritoneal DialysisOFFSIDES
535Pharyngolaryngeal PainOFFSIDES
536PhlebitisOFFSIDES
537Physical disabilityOFFSIDES
538Pilonidal CystOFFSIDES
539PlasmacytomaOFFSIDES
SIDER
540PlasmacytosisOFFSIDES
541PolyuriaOFFSIDES
542Portal HypertensionOFFSIDES
543Postmenopausal bleedingOFFSIDES
544Postrenal failureOFFSIDES
545PovertyOFFSIDES
546Prescription drug used without a prescriptionCanada Vigilance: 1Canada Vigilance
547Primary Myelofibrosis1803051CTD
548Primary sequestrumOFFSIDES
549Prostatic Neoplasms15749863CTD
550ProteinuriaCanada Vigilance: 1Canada Vigilance
551Pseudomonal sepsisOFFSIDES
552PsoriasisOFFSIDES
553PurulenceOFFSIDES
554Purulent dischargeOFFSIDES
555Radiation skin injuryOFFSIDES
556RalesOFFSIDES
SIDER
557Rebound effectOFFSIDES
558Renal Insufficiency3597002
9404925		CTD
559Reticulocyte count increasedOFFSIDES
560RetinitisOFFSIDES
561RhinitisOFFSIDES
562RhinorrheaOFFSIDES
563Risus sardonicusOFFSIDES
564Sarcoma, Experimental3698174CTD
565Sarcoma, Myeloid11099330CTD
566Sensation of warmthSIDER
567SequestrectomyOFFSIDES
568Serum SicknessOFFSIDES
569Sick Sinus SyndromeOFFSIDES
570Sinus operationOFFSIDES
571Sinus rhythmOFFSIDES
572SinusitisOFFSIDES
573Skeletal survey abnormalOFFSIDES
574Skin Neoplasms14993021CTD
575Skin UlcerSIDER
576Skin lacerationOFFSIDES
577Skin necrosisSIDER
578Skin neoplasm excisionOFFSIDES
579Soft Tissue InfectionOFFSIDES
580Soft tissue inflammationOFFSIDES
581Spinal column stenosisOFFSIDES
582SpondylitisOFFSIDES
583SpondylolisthesisOFFSIDES
584Staphylococcal Scalded Skin SyndromeOFFSIDES
585Stenotrophomonas infectionOFFSIDES
586Stevens-Johnson SyndromeOFFSIDES
587Subcutaneous noduleOFFSIDES
588Synovial CystOFFSIDES
589ThoracotomyOFFSIDES
590Thrombocythemia, Essential11099330CTD
591ThyroiditisOFFSIDES
592Tobacco userOFFSIDES
593Tooth ExtractionOFFSIDES
594Tooth InfectionOFFSIDES
595Tooth LossOFFSIDES
596Tooth ResorptionOFFSIDES
597Treatment related secondary malignancyOFFSIDES
598Tumor Lysis Syndrome18463870CTD
599UlcerSIDER
600UrticariaSIDER
601VIIth nerve paralysisOFFSIDES
602Vasculitis713003CTD
SIDER
603Vena cava filter insertionOFFSIDES
604Venous InsufficiencyOFFSIDES
605Ventricular Dysfunction, Left11498753
18548196		CTD
606VertebroplastyOFFSIDES
607Viral DNA test positiveOFFSIDES
608Viral upper respiratory tract infectionOFFSIDES
609Wound ComplicationOFFSIDES
610Wound DebridementOFFSIDES
611Wound dehiscenceOFFSIDES
612colonoscopyOFFSIDES
613fibromaOFFSIDES
614jaundiceSIDER
615kyphosisOFFSIDES
616melanoma

View details

7802575
7995421
9843018
10379864
14993021
18388930
 		CTD
617muscle injurySIDER
618prostatitisOFFSIDES
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