Cefoxitin
(WZOZEZRFJCJXNZ-ZBFHGGJFSA-N)
Structure
- SMILES
- CO[C@@]1(NC(=O)Cc2cccs2)C(=O)N2[C@@H]1SCC(=C2C(=O)O)COC(=O)N
- Type(s)
- Approved
- ATC code(s)
- J01DC01
- Molecular Formula:
- C16H17N3O7S2
- Molecular Weight:
- 427.452
- Log P:
- 1.1277
- Hydrogen Bond Acceptor:
- 12
- Hydrogen Bond Donor:
- 3
- TPSA:
- 201.8
- CAS Number(s):
- 35607-66-0
Synonym(s)
1.
Cefoxitin
2.
Cefoxitin Sodium
3.
MK-306
4.
Mefoxin
5.
Mefoxitin
6.
Méfoxin
7.
MK 306
8.
MK306
9.
Sodium, Cefoxitin
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Hypotension | FAERS: 4 Canada Vigilance: 2 | 6486149 | CTD SIDER Canada Vigilance US FAERS |
| 2 | Megacolon | FAERS: 3 | OFFSIDES US FAERS | |
| 3 | Sepsis | FAERS: 3 | US FAERS | |
| 4 | Acidosis | FAERS: 2 | OFFSIDES US FAERS | |
| 5 | Blood creatine increased | FAERS: 2 | OFFSIDES US FAERS | |
| 6 | Clostridium colitis | FAERS: 2 | OFFSIDES US FAERS | |
| 7 | Clostridium difficile colitis | FAERS: 2 | OFFSIDES US FAERS | |
| 8 | Deep Vein Thrombosis | FAERS: 2 | US FAERS | |
| 9 | Erythema | FAERS: 2 Canada Vigilance: 5 | Canada Vigilance SIDER US FAERS | |
| 10 | Hypersensitivity | FAERS: 2 | SIDER US FAERS | |
| 11 | Hypoxia | FAERS: 2 | US FAERS | |
| 12 | Ileitis | FAERS: 2 | OFFSIDES US FAERS | |
| 13 | Peritonitis | FAERS: 2 | US FAERS | |
| 14 | Pneumonia | FAERS: 2 | US FAERS | |
| 15 | Post procedural complication | FAERS: 2 | OFFSIDES US FAERS | |
| 16 | Pruritus | FAERS: 2 Canada Vigilance: 7 | Canada Vigilance SIDER US FAERS | |
| 17 | Respiratory Failure | FAERS: 2 | US FAERS | |
| 18 | Septic Shock | FAERS: 2 | OFFSIDES US FAERS | |
| 19 | Urinary tract infection | FAERS: 2 | US FAERS | |
| 20 | pseudomembranous colitis | FAERS: 2 | SIDER US FAERS | |
| 21 | Anxiety | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 22 | Blood creatine phosphokinase MB abnormal | FAERS: 1 | US FAERS | |
| 23 | Blood urea increased | FAERS: 1 | US FAERS | |
| 24 | Bradycardia | FAERS: 1 | OFFSIDES US FAERS | |
| 25 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 26 | Catatonia | FAERS: 1 | US FAERS | |
| 27 | Chest discomfort | FAERS: 1 | US FAERS | |
| 28 | Clostridium difficile infection | FAERS: 1 | US FAERS | |
| 29 | Dermatitis | FAERS: 1 | SIDER US FAERS | |
| 30 | Drug prescribing error | FAERS: 1 | US FAERS | |
| 31 | Epistaxis | FAERS: 1 | US FAERS | |
| 32 | Intercepted medication error | FAERS: 1 | US FAERS | |
| 33 | Lethargy | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 34 | Mental status changes | FAERS: 1 | US FAERS | |
| 35 | Myocardial Infarction | FAERS: 1 | 15881565 | CTD US FAERS |
| 36 | Myoclonus | FAERS: 1 | US FAERS | |
| 37 | Neutropenia | FAERS: 1 | SIDER US FAERS | |
| 38 | Pancytopenia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 39 | Phlebitis | FAERS: 1 Canada Vigilance: 6 | Canada Vigilance SIDER US FAERS | |
| 40 | Procedural complication | FAERS: 1 | OFFSIDES US FAERS | |
| 41 | Product contamination physical | FAERS: 1 | US FAERS | |
| 42 | Product label confusion | FAERS: 1 | US FAERS | |
| 43 | Tachycardia | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 44 | Tremor | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 45 | Troponin I increased | FAERS: 1 | US FAERS | |
| 46 | White blood cell count decreased | FAERS: 1 | US FAERS | |
| 47 | Abdominal Pain | OFFSIDES SIDER | ||
| 48 | Abdominal discomfort | OFFSIDES | ||
| 49 | Acid reflux | OFFSIDES | ||
| 50 | Acute prerenal failure | SIDER | ||
| 51 | Adnexitis | OFFSIDES | ||
| 52 | Agranulocytosis | 6641504 | CTD SIDER | |
| 53 | Alveolitis | OFFSIDES | ||
| 54 | Anal Fissure | OFFSIDES | ||
| 55 | Anaphylactic shock | SIDER | ||
| 56 | Anaphylactoid Reaction | Canada Vigilance: 2 | Canada Vigilance | |
| 57 | Anemia, Hemolytic | 6641504 10204595 17381629 | CTD | |
| 58 | Anger | OFFSIDES | ||
| 59 | Angioedema | SIDER | ||
| 60 | Appendectomy | OFFSIDES | ||
| 61 | Appendicitis | OFFSIDES | ||
| 62 | Asthenia | OFFSIDES | ||
| 63 | Asthma | OFFSIDES | ||
| 64 | Atelectasis | OFFSIDES | ||
| 65 | Atrial Fibrillation | 6486149 | CTD | |
| 66 | Blood Glucose | OFFSIDES | ||
| 67 | Blood phosphorus decreased | OFFSIDES | ||
| 68 | Bone erosion | OFFSIDES | ||
| 69 | Bone fragmentation | OFFSIDES | ||
| 70 | Bone marrow depression | OFFSIDES SIDER | ||
| 71 | Bone pain | OFFSIDES | ||
| 72 | Bronchopneumonia | OFFSIDES | ||
| 73 | Bronchospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 74 | Bruxism | OFFSIDES | ||
| 75 | Bursitis | OFFSIDES | ||
| 76 | CREST Syndrome | OFFSIDES | ||
| 77 | Cellulitis | OFFSIDES | ||
| 78 | Chills | Canada Vigilance: 1 | Canada Vigilance | |
| 79 | Cholestasis | SIDER | ||
| 80 | Chronic ulcerative colitis | OFFSIDES | ||
| 81 | Colitis | SIDER | ||
| 82 | Congenital tricuspid valve incompetence | OFFSIDES | ||
| 83 | Cytolytic hepatitis | OFFSIDES | ||
| 84 | Dental abscess | OFFSIDES | ||
| 85 | Dental caries | OFFSIDES | ||
| 86 | Device Failure | OFFSIDES | ||
| 87 | Diabetes | OFFSIDES | ||
| 88 | Diarrhea | 531523 | CTD OFFSIDES | |
| 89 | Diffuse Large B-Cell Lymphoma | OFFSIDES | ||
| 90 | Disseminated Intravascular Coagulation | 6486149 | CTD | |
| 91 | Diverticular perforation | OFFSIDES | ||
| 92 | Diverticulitis | OFFSIDES | ||
| 93 | Diverticulum | OFFSIDES | ||
| 94 | Dizziness | Canada Vigilance: 1 | Canada Vigilance | |
| 95 | Drug Eruptions | 6486149 | CTD | |
| 96 | Dyspepsia | OFFSIDES | ||
| 97 | Eczema weeping | OFFSIDES | ||
| 98 | Embolism | OFFSIDES | ||
| 99 | Endocarditis | OFFSIDES | ||
| 100 | Endodontic procedure | OFFSIDES | ||
| 101 | Enteritis | OFFSIDES | ||
| 102 | Enterococcal infection | OFFSIDES | ||
| 103 | Eosinophilia | SIDER | ||
| 104 | Epstein-Barr virus test positive | OFFSIDES | ||
| 105 | Erythema Multiforme | OFFSIDES SIDER | ||
| 106 | Escherichia infection | OFFSIDES | ||
| 107 | Eye laser surgery | OFFSIDES | ||
| 108 | Facial Neuralgia | OFFSIDES | ||
| 109 | Fatigue | OFFSIDES | ||
| 110 | Flushing | SIDER | ||
| 111 | Gastroduodenitis | OFFSIDES | ||
| 112 | Gastrointestinal Pain | SIDER | ||
| 113 | General physical health deterioration | OFFSIDES | ||
| 114 | Globulinuria | OFFSIDES | ||
| 115 | Gonorrhea | 6228024 | CTD | |
| 116 | Granulocytosis | OFFSIDES | ||
| 117 | Granuloma | OFFSIDES | ||
| 118 | Headache | Canada Vigilance: 1 | Canada Vigilance | |
| 119 | Hepatosplenomegaly | OFFSIDES | ||
| 120 | Immune Complex Diseases | 10204595 | CTD | |
| 121 | Incorrect dose administered | OFFSIDES | ||
| 122 | Induration | SIDER | ||
| 123 | Infection | 3536491 | CTD | |
| 124 | Inguinal mass | OFFSIDES | ||
| 125 | Injection Site Reaction | Canada Vigilance: 6 | Canada Vigilance | |
| 126 | Intestinal infarction | OFFSIDES | ||
| 127 | Joint sprain | OFFSIDES | ||
| 128 | Kidney Failure | OFFSIDES | ||
| 129 | Leukopenia | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 130 | Local reaction | SIDER | ||
| 131 | Lymphocele | OFFSIDES | ||
| 132 | Malocclusion | OFFSIDES | ||
| 133 | Metabolic acidosis | OFFSIDES | ||
| 134 | Metastatic Neoplasm | OFFSIDES | ||
| 135 | Mixed Connective Tissue Disease | OFFSIDES | ||
| 136 | Myasthenia Gravis | SIDER | ||
| 137 | Nausea | Canada Vigilance: 3 | Canada Vigilance OFFSIDES SIDER | |
| 138 | Nephritis, Interstitial | 7283579 | CTD | |
| 139 | Oliguria | OFFSIDES | ||
| 140 | Osteitis Deformans | OFFSIDES | ||
| 141 | Osteolysis | OFFSIDES | ||
| 142 | Osteomyelitis | OFFSIDES | ||
| 143 | Osteopenia | OFFSIDES | ||
| 144 | Osteoporosis | OFFSIDES | ||
| 145 | Pain | Canada Vigilance: 1 | Canada Vigilance OFFSIDES SIDER | |
| 146 | Pallor | Canada Vigilance: 1 | Canada Vigilance | |
| 147 | Pericardial effusion | OFFSIDES | ||
| 148 | Periodontitis | OFFSIDES | ||
| 149 | Petechiae | Canada Vigilance: 1 | Canada Vigilance | |
| 150 | Poor dental condition | OFFSIDES | ||
| 151 | Pulmonary Edema | 6486149 | CTD | |
| 152 | Pulmonary Embolism | Canada Vigilance: 1 | Canada Vigilance | |
| 153 | Purpura | 2309515 | CTD | |
| 154 | Rales | OFFSIDES | ||
| 155 | Rash erythematous | Canada Vigilance: 6 | Canada Vigilance | |
| 156 | Renal tubular disorder | OFFSIDES | ||
| 157 | Renal tubular necrosis | OFFSIDES | ||
| 158 | Respiratory Sounds | 6486149 | CTD | |
| 159 | Sacroiliitis | OFFSIDES | ||
| 160 | Scab | OFFSIDES | ||
| 161 | Scan bone marrow abnormal | OFFSIDES | ||
| 162 | Scleroderma | OFFSIDES | ||
| 163 | Seroma | OFFSIDES | ||
| 164 | Serum Sickness | SIDER | ||
| 165 | Sinusitis | OFFSIDES | ||
| 166 | Sjogren's Syndrome | OFFSIDES | ||
| 167 | Somnolence | Canada Vigilance: 1 | Canada Vigilance | |
| 168 | Status Epilepticus | OFFSIDES | ||
| 169 | Stevens-Johnson Syndrome | 25811541 | CTD SIDER | |
| 170 | Superficial Thrombophlebitis | OFFSIDES | ||
| 171 | Superinfection | SIDER | ||
| 172 | Tetany | OFFSIDES | ||
| 173 | Thrombocytopenia | 6641504 | CTD SIDER | |
| 174 | Thrombophlebitis | 531523 | CTD SIDER | |
| 175 | Tooth Extraction | OFFSIDES | ||
| 176 | Toxic Epidermal Necrolysis | SIDER | ||
| 177 | Urticaria | Canada Vigilance: 9 | 6486149 | CTD SIDER Canada Vigilance |
| 178 | Ventricular hypokinesia | OFFSIDES | ||
| 179 | Visual disturbance | OFFSIDES | ||
| 180 | Vitreous Detachment | OFFSIDES | ||
| 181 | Vomiting | SIDER | ||
| 182 | Vulvovaginal mycotic infection | SIDER | ||
| 183 | Wound dehiscence | OFFSIDES | ||
| 184 | Wound infection staphylococcal | OFFSIDES | ||
| 185 | anaphylaxis | 6486149 10204595 15881565 | CTD | |
| 186 | jaundice | 6641504 | CTD SIDER |
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