MetaADEDB 2.0 @ LMMD
Desoximetasone
(VWVSBHGCDBMOOT-IIEHVVJPSA-N)
Structure
SMILES
OCC(=O)[C@H]1[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F
Type(s)
Approved
ATC code(s)
D07AC03; D07XC02
Molecular Formula:
C22H29FO4
Molecular Weight:
376.462
Log P:
2.7808
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
74.6
CAS Number(s):
382-67-2
Synonym(s)
1.
Desoximetasone
2.
Deoxydexamethasone
3.
Desoxymethasone
4.
17-Desoxymethasone
5.
A-41304
6.
Desoxi
7.
Flubason
8.
Ibaril
9.
Stiedex
10.
Topicort
11.
Topicorte
12.
Topisolon
13.
17 Desoxymethasone
14.
A 41304
15.
A41304
External Link(s)
MeSHD003899
PubChem Compound5311067
BindingDB50103622
ChEBI691037
CHEMBLCHEMBL1766
DrugBankDB00547
DrugCentral819
IUPHAR/BPS Guide to PHARMACOLOGY7067
KEGGdr:D03697
Therapeutic Target DatabaseD0CZ1Q
ZINC4212854
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 13
Canada Vigilance: 9		Canada Vigilance
US FAERS
2Application site painFAERS: 6OFFSIDES
US FAERS
3Product quality issueFAERS: 4US FAERS
4Product substitution issueFAERS: 4US FAERS
5Accidental exposure to productFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
6AlopeciaFAERS: 3OFFSIDES
US FAERS
7Burning sensationFAERS: 3SIDER
US FAERS
8HypersensitivityFAERS: 3US FAERS
9PainFAERS: 3
Canada Vigilance: 1		18591846CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
10Application site burnFAERS: 2US FAERS
11Drug effect incompleteFAERS: 2US FAERS
12Drug ineffective for unapproved indicationFAERS: 2US FAERS
13ErythemaFAERS: 2OFFSIDES
SIDER
US FAERS
14Eye irritationFAERS: 2US FAERS
15Inappropriate schedule of drug administrationFAERS: 2US FAERS
16Medication ErrorFAERS: 2US FAERS
17PruritusFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
18Vulvovaginal discomfortFAERS: 2US FAERS
19Wrong drug administeredFAERS: 2US FAERS
20AbasiaFAERS: 1US FAERS
21Accidental exposure to product by childFAERS: 1US FAERS
22Accidental exposureFAERS: 1US FAERS
23Accidental overdoseFAERS: 1US FAERS
24Allergy test positiveFAERS: 1US FAERS
25Aphthous StomatitisFAERS: 1US FAERS
26Application site erythemaFAERS: 1OFFSIDES
US FAERS
27Application site irritationFAERS: 1SIDER
US FAERS
28Application site pruritusFAERS: 1SIDER
US FAERS
29Application site swellingFAERS: 1US FAERS
30Blood urine presentFAERS: 1US FAERS
31Drug dispensing errorFAERS: 1US FAERS
32Drug effect delayedFAERS: 1US FAERS
33Expired product administeredFAERS: 1US FAERS
34Exposure via direct contactFAERS: 1US FAERS
35Eye painFAERS: 1US FAERS
36Foreign body sensation in eyesFAERS: 1US FAERS
37Genital HerpesFAERS: 1US FAERS
38Head discomfortFAERS: 1US FAERS
39HeadacheFAERS: 1US FAERS
40Incorrect drug administration durationFAERS: 1US FAERS
41Incorrect route of drug administrationFAERS: 1US FAERS
42Intercepted drug dispensing errorFAERS: 1US FAERS
43Medical device implantationFAERS: 1US FAERS
44Muscle tightnessFAERS: 1US FAERS
45Nasal discomfortFAERS: 1US FAERS
46NasopharyngitisFAERS: 1US FAERS
47NervousnessFAERS: 1US FAERS
48Pain of skinFAERS: 1US FAERS
49Peripheral swellingFAERS: 1US FAERS
50Product administered at inappropriate siteFAERS: 1US FAERS
51PsoriasisFAERS: 1OFFSIDES
SIDER
US FAERS
52Reaction to drug excipientsFAERS: 1US FAERS
53Skin irritationFAERS: 1US FAERS
54Thermal burnFAERS: 1US FAERS
55Tinea PedisFAERS: 1US FAERS
56Unevaluable eventFAERS: 1US FAERS
57Urinary tract infectionFAERS: 1US FAERS
58VitiligoFAERS: 1US FAERS
59Abdominal PainOFFSIDES
60Abdominal discomfortOFFSIDES
61Acid refluxOFFSIDES
62AcneSIDER
63Acute myocardial infarctionOFFSIDES
64Adrenal massOFFSIDES
65AmnesiaOFFSIDES
66AnhidrosisOFFSIDES
67Ankle FractureOFFSIDES
68Anoxic EncephalopathyOFFSIDES
69AnxietyOFFSIDES
70Application site drynessSIDER
71Application site reactionOFFSIDES
72ArteriosclerosisOFFSIDES
73ArthritisOFFSIDES
74AstheniaOFFSIDES
75AsthmaOFFSIDES
76AtherosclerosisOFFSIDES
77Bacterial conjunctivitisOFFSIDES
78Basal cell carcinomaOFFSIDES
79Blood creatinine increasedOFFSIDES
80Blood sodiumOFFSIDES
81Bone painOFFSIDES
82BradycardiaCanada Vigilance: 1Canada Vigilance
83BronchitisOFFSIDES
84BruxismOFFSIDES
85BursitisOFFSIDES
86Cardiovascular insufficiencyOFFSIDES
87CataractOFFSIDES
88Catheter site related reactionOFFSIDES
89CellulitisOFFSIDES
90Chest PainOFFSIDES
91Chronic ulcerative colitisOFFSIDES
92ColitisOFFSIDES
93ComedoneSIDER
94Contact DermatitisOFFSIDES
95Corneal dystrophyOFFSIDES
96DebridementOFFSIDES
97Delayed sleep phaseOFFSIDES
98DemyelinationOFFSIDES
99Dermatitis acneiformSIDER
100DermatitisSIDER
101DiabetesOFFSIDES
102DiarrheaOFFSIDES
103DiverticulumOFFSIDES
104DizzinessOFFSIDES
105Drug addictOFFSIDES
106Drug exposure during pregnancyOFFSIDES
107Drug withdrawal headacheOFFSIDES
108DysmenorrheaOFFSIDES
109DysuriaOFFSIDES
110FatigueOFFSIDES
111Fatty Liver18591846CTD
OFFSIDES
112Febrile NeutropeniaOFFSIDES
113Fibroadenoma of breastOFFSIDES
114FolliculitisOFFSIDES
SIDER
115FormicationOFFSIDES
116GamblingOFFSIDES
117GastroenteritisOFFSIDES
118General physical health deteriorationOFFSIDES
119GlobulinuriaOFFSIDES
120GlycosuriaSIDER
121Graft infectionOFFSIDES
122Hepatic congestionOFFSIDES
123Hyperglycemia18591846CTD
124Hypertensive heart diseaseOFFSIDES
125HypertrichosisSIDER
126HypogonadismOFFSIDES
127InfectionSIDER
128InfertilityOFFSIDES
129IntertrigoOFFSIDES
130Kidney FailureOFFSIDES
131Left atrial dilatationOFFSIDES
132LeukodermaSIDER
133LymphedemaOFFSIDES
134MastectomyOFFSIDES
135MicroalbuminuriaOFFSIDES
136MicrocytosisOFFSIDES
137MiliariaSIDER
138MononeuritisOFFSIDES
139Multiple SclerosisOFFSIDES
140Muscle WeaknessOFFSIDES
141Musculoskeletal stiffnessOFFSIDES
142MyelodysplasiaOFFSIDES
143NeuralgiaOFFSIDES
144Nonspecific reactionOFFSIDES
145OsteolysisOFFSIDES
146OsteomyelitisOFFSIDES
147OsteopeniaOFFSIDES
148PeriodontitisOFFSIDES
149Periportal sinus dilatationOFFSIDES
150Pharyngeal lesionOFFSIDES
151PouchitisOFFSIDES
152Product complaintCanada Vigilance: 1Canada Vigilance
153Pulmonary InfarctionOFFSIDES
154Pyoderma GangrenosumOFFSIDES
155PyodermaSIDER
156SclerodermaOFFSIDES
157ScotomaOFFSIDES
158SeromaOFFSIDES
159Sick Sinus SyndromeOFFSIDES
160SinusitisOFFSIDES
161Skin lesionOFFSIDES
162Sputum culture positiveOFFSIDES
163StressOFFSIDES
164T-cell lymphoma stage IVOFFSIDES
165TendinitisOFFSIDES
166Terminal stateOFFSIDES
167Therapy non-responderOFFSIDES
168TonsillectomyOFFSIDES
169UlcerOFFSIDES
170Ulnar NeuritisOFFSIDES
171Wound infection pseudomonasOFFSIDES
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